|
T8708 |
Paroxetine
|
|
Serotonin Transporter
|
|
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. |
|
T22453 |
Venlafaxine
|
Wy 45030 |
Serotonin Transporter
|
|
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia. |
|
T0472 |
Venlafaxine hydrochloride
|
Venlafaxine HCl,Wy 45030 hydrochloride |
5-HT Receptor
,
Serotonin Transporter
|
|
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT. |
|
T21029 |
Norfluoxetine Hydrochloride
|
Norfluoxetine HCl |
Others
|
|
Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. |
|
T6493 |
Escitalopram Oxalate
|
Cipralex,(S)-(+)Citalopram oxalate |
Others
,
5-HT Receptor
,
Serotonin Transporter
|
|
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM. |
|
T21013 |
Clomipramine
|
Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina |
5-HT Receptor
|
|
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su... |
|
T0255 |
Clomipramine hydrochloride
|
Clomipramine HCl,Anafranil |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
,
GST
|
|
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth... |
|
T6461 |
Dapoxetine hydrochloride
|
LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy |
5-HT Receptor
,
Serotonin Transporter
|
|
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation. |
|
T3275 |
Nefazodone hydrochloride
|
Dutonin,MJ-13754-1,Serzone,BMY-13754-1,BMY-13754 |
5-HT Receptor
,
Adrenergic Receptor
|
|
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder. |
|
T1483 |
Citalopram hydrobromide
|
Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr |
5-HT Receptor
,
Serotonin Transporter
,
Autophagy
|
|
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system... |
|
T0039 |
Dapoxetine
|
Dapoxetina,Dapoxetinum |
Others
,
5-HT Receptor
|
|
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. |
|
T7061 |
Duloxetine
|
|
Serotonin Transporter
|
|
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder. |
|
T6963 |
Reboxetine mesylate
|
FCE20124 mesylate,Edronax,PNU155950E mesylate,PNU 155950E |
Adrenergic Receptor
,
Norepinephrine
|
|
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM). |
|
T28380 |
PF-184298
|
PF184298,PF 184298 |
Dopamine Receptor
,
5-HT Receptor
|
|
PF-184298 is a serotonin and norepinephrine monoamine reuptake inhibitor (SNRI) that inhibits dopamine reuptake. |
|
T7308 |
Nomifensine
|
NOMIFENSINE MALEATE,(±)-Nomifensin |
Dopamine Receptor
|
|
Nomifensine ((±)-Nomifensin) is a norepinephrine-dopamine reuptake inhibitor that prevents dopamine reuptake into synaptosomes. |
|
T2092 |
Amitifadine hydrochloride
|
DOV-21947 hydrochloride,EB-1010 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). |
|
T24661 |
Pridefine
|
Pridefina |
|
|
Pridefine is an antidepressant drug. It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine. It also has some weak releasing activity. |
|
T24444 |
Medifoxamine
|
LG 152,Medifoxamina,LG-152,LG152 |
Dopamine Receptor
,
Monoamine Oxidase
|
|
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine preferentially inhibits dopamine reuptake. |
|
T32737 |
Liafensine
|
BMS820836,BMS 820836,DB104,BMS-820836 |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and centra... |
|
T8443 |
MCI-225
|
|
Norepinephrine
|
|
MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism. |
|
T68040 |
Cericlamine
|
|
5-HT Receptor
|
|
Cericlamine is a selective 5-hydroxytryptamine (5-HT) reuptake blocker with antidepressant activity. |
|
T7940 |
Milnacipran ((1S-cis) hydrochloride)
|
Levomilnacipran Hydrochloride |
Serotonin Transporter
|
|
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia. |
|
T26126 |
Roxindole
|
|
|
|
Roxindole is an effective autoreceptor-selective dopamine agonist with additional properties as a serotonin reuptake inhibitor and 5-HT1A agonist. It was originally developed for the therapy of schizophrenic syndromes. |
|
T34795 |
Tedatioxetine
|
Lu AA 24530,Lu AA-24530,Lu AA24530 |
Dopamine Receptor
,
Serotonin Transporter
|
|
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substrate. |
|
T7118 |
Dimethocaine
|
Larocaine |
Others
,
Dopamine Receptor
|
|
Dimethocaine (Larocaine) is a local anesthetic which also effects on the central nervous system acting as dopamine-reuptake-inhibitor. |
|
T60330 |
Metapramine
|
|
|
|
Metapramine (19560 RP) is a tricyclic antidepressant[1]. Metapramine inhibits norepinephrine reuptake without affecting the reuptake of serotonin or dopamine [1] [2] [3]. Metapramine is a low-affinity antagonist of the N... |
|
T20828 |
Citalopram
|
Cipram,Lu 10-171,Lu-10-171 Lu10-171 |
5-HT Receptor
|
|
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enant... |
|
T4262 |
BisfluoroModafinil
|
|
Dopamine Receptor
|
|
CRL-40940 is a selective dopaminergic reuptake inhibitor |
|
T1636L |
Paroxetine hydrochloride hemihydrate
|
Paroxetine Hydrochloride,Paxil,Paroxetine HCl,Seroxat |
5-HT Receptor
|
|
Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI). |
|
T32633 |
Lensiprazine
|
SLV314,SLV-314,SLV 314 |
Dopamine Receptor
,
5-HT Receptor
|
|
Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and schizophrenia. |
|
T13110 |
Tedatioxetine hydrobromide
|
Lu AA 24530 hydrobromide |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) is a serotonin-norepinephrine-dopamine reuptake inhibitor and an antagonist of 5-HT2A, 5-HT2C, 5-HT3, and α1A-adrenergic receptors, which can be used to treat depress... |
|
T31750 |
Faxeladol
|
EM906,GCR 9905,EM 906,GCR-9905,EM-906,GCR9905 |
5-HT Receptor
,
Opioid Receptor
,
Adrenergic Receptor
|
|
Faxeladol, a potent adrenergic absorption inhibitor and serotonin reuptake inhibitor, is a small-molecule Opioid receptor agonist that can be used to study neurological disorders. |
|
T0450 |
Fluoxetine
|
LY-110140 |
5-HT Receptor
,
Serotonin Transporter
,
MRP
,
Autophagy
|
|
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity. |
|
T6232 |
Vilazodone Hydrochloride
|
SB659746A,EMD 68843,Vilazodone HCl |
Others
,
5-HT Receptor
,
Serotonin Transporter
|
|
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder. |
|
T1279 |
Vilazodone
|
SB659746A,EMD 68843 |
5-HT Receptor
,
Serotonin Transporter
|
|
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from... |
|
T69096 |
Femoxetine hydrochloride
|
|
5-HT Receptor
|
|
Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders. |
|
T28809 |
SLV-310
|
SLV 310,SLV310 |
Dopamine Receptor
,
5-HT Receptor
|
|
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia. |
|
T2402 |
Tianeptine sodium salt
|
Tianeptine sodium |
5-HT Receptor
|
|
Tianeptine sodium salt is a selective serotonin reuptake enhancer (SSRE), used to treat major depressive episodes. |
|
T5380 |
Ansofaxine hydrochloride
|
LPM570065,LY03005 |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively). |
|
T2594 |
Dextromilnacipran
|
Levomilnacipran |
Serotonin Transporter
,
Norepinephrine
|
|
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor. |
|
T22420 |
(S)-Viloxazine Hydrochloride
|
(S)-Viloxazine HCl |
Norepinephrine
|
|
(S)-Viloxazine Hydrochloride, the S-isomer of Viloxazine. Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. |
|
T1077 |
Fluvoxamine maleate
|
MK-264,DU-23000 (maleate) |
5-HT Receptor
,
Serotonin Transporter
|
|
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders. |
|
T22413 |
(R)-Viloxazine Hydrochloride
|
|
Others
|
|
(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine. Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) and can be used as an antidepressant. |
|
T3648 |
Hypidone hydrochloride
|
YL0919 |
5-HT Receptor
|
|
Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor. |
|
T8633 |
9-FLUORENOL
|
|
Dopamine Receptor
|
|
9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 µM, and a major metabolite of a compound developed as a wakefulness-promoting agent. |
|
T7000 |
Tiagabine hydrochloride
|
NO328 hydrochloride,NO050328 hydrochloride,TGB hydrochloride,Gabitril,Gabitril hydrochloride |
GABA Receptor
|
|
Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
|
T12232 |
Nitroxazepine
|
CIBA 2330Go |
Serotonin Transporter
|
|
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression |
|
T3526 |
Dasotraline hydrochloride
|
SEP-225289 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe... |
|
T0059 |
Diphenylpyraline hydrochloride
|
4-Diphenylmethoxy-1-methylpiperidine hydrochloride |
Histamine Receptor
|
|
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... |
|
T11087 |
DOV-216,303 Free Base
|
DOV-216303 |
Dopamine Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
|
