|
T2455 |
PFK-015
|
PFK15,PFK 015 |
Glucokinase
,
Autophagy
|
|
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). |
|
T0786 |
Clidinium bromide
|
Ro 2-3773 |
AChR
|
|
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... |
|
T1575 |
Nizatidine
|
Axid,Acinon,Zanizal |
AChE
,
Histamine Receptor
|
|
Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity. |
|
T0424 |
Bismuth Subsalicylate
|
Bismuth subsalicylat,Bismuth(III) salicylate basic,Bismuth oxysalicylate |
COX
,
PGE Synthase
|
|
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts ... |
|
T6415 |
Bismuth Subcitrate Potassium
|
|
Others
,
Antibacterial
,
Antibiotic
|
|
Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection. |
|
TP2030L1 |
Gastrin I (human) acetate
|
Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate |
cholecystokinin
|
|
Gastrin I (human) acetate (Gastrin-17 acetate) is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. |
|
TP2030 |
Gastrin I, human
|
Gastrin I (human) |
cholecystokinin
|
|
Gastrin I, human (Gastrin I (human)) is an endogenous peptide produced in the stomach that increases pepsinogen and acid secretion via the CCK2 receptor in the rat. |
|
T0594 |
Diphenmanil methylsulfate
|
Diphemanil mesylate,Diphemanil Methylsulfate |
AChR
|
|
Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acids, sweat, and saliva. |
|
T0865 |
Ranitidine Hydrochloride
|
AH19065 |
P450
,
Antibacterial
,
Histamine Receptor
|
|
Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enteroc... |
|
T72107 |
Werner syndrome RecQ helicase-IN-1
|
|
DNA/RNA Synthesis
|
|
Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer. |
|
T6710 |
Troxipide
|
Aplace |
Others
|
|
Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum. |
|
T3937 |
Methyl L-histidinate dihydrochloride
|
L-Histidine methyl ester dihydrochloride |
HDAC
|
|
The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production with activty valu... |
|
T0992 |
Carbenoxolone disodium
|
Biogastrone,Duogastrone,Bioral |
Gap Junction Protein
|
|
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... |
|
T0674 |
Lansoprazole
|
A-65006,AG-1749 |
Proton pump
,
Phospholipase
,
Antibacterial
|
|
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo... |
|
T1651 |
Rabeprazole sodium
|
Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium |
Apoptosis
,
Proton pump
|
|
Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch... |
|
TP1325L |
Gastrin-Releasing Peptide, human(TFA)
|
|
Others
|
|
Gastrin-Releasing Peptide, human(TFA) is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innerva... |
|
T4616 |
Metoclopramide
|
5-Chloro-2-methoxyprocainamide |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ... |
|
T31743 |
Famotine hydrochloride
|
Famotine HCl,UK-2054 |
|
|
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease. |
|
T32599 |
Lauroylglycyrrhetinic acid
|
BX 24,BX24,BX-24 |
|
|
Lauroylglycyrrhetinic acid, an analog of carbenoxolone, can be used in the treatment of stomach ulcer. |
|
T20775 |
Ranitidine-N-oxide
|
|
|
|
Ranitidine-N-oxide is a metabolite of Ranitidine. Ranitidine is a antagonist of histamine H2-receptor, it inhibits the normal and meal-stimulated secretion of stomach acid. Ranitidine is a medication decreaseing stomach ... |
|
T34566 |
Sch 12223
|
Sch12223,Sch-12223 |
|
|
SCH 12223 is a unique drug that protects the stomach and intestinal epithelium from harmful irritation. |
|
T28331 |
PD 136450
|
Cam1189,PD136450,Cam-1189,PD-136450,Cam 1189 |
|
|
Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to... |
|
T18310 |
AZ1508
|
MC-Lys-MMETA |
Others
|
|
AZ1508, a tubulin inhibitor[1], serves as a drug-linker conjugate for antibody-drug conjugates (ADC) targeting breast and stomach cancer treatment. |
|
T11816 |
Lansoprazole-d4
|
AG-1749 D4,Lansoprazole D4 |
Proton pump
|
|
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid. |
|
T70127 |
Famotine
|
|
|
|
Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T37642 |
Pravastatin lactone
|
|
|
|
Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin ... |
|
T71049 |
Famotidine disulfide
|
|
|
|
Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T71485 |
Famotidine propionic acid
|
|
|
|
Famotidine propionic acid is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T71509 |
Famotidine sulfamoyl propanamide
|
|
|
|
Famotidine sulfamoyl propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T68725 |
Famotidine propanamide
|
|
|
|
Famotidine propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T70090 |
Nizatidine amide
|
|
|
|
Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T33314 |
Methantheline Bromide
|
Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide |
|
|
Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre... |
|
TP1325 |
Gastrin-Releasing Peptide, human
|
|
|
|
Gastrin-Releasing Peptide, human is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate th... |
|
T61453 |
Propantheline
|
|
|
|
Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intes... |
|
T40850 |
[D-Trp11]-Neurotensin
|
[D-Trp11]-Neurotensin |
|
|
[D-Trp11]-Neurotensin is a compound that functions as a selective antagonist of Neurotensin (NT) in perfused rat hearts, while exhibiting full agonist properties in guinea pig atria and rat stomach strips. Additionally, ... |
|
T37588 |
GIP (1-30) amide, porcine
|
|
|
|
This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic a... |
|
T28612 |
RP-72540
|
RPR 102681,RPR-102681,RPR102681 |
|
|
RP-72540 is a cholecystokinin B receptor antagonist. RP 72540 showed selectivity factors in express of 200 for CCKA versus CCKB receptors and also had high affinity for gastrin binding sites in the stomach. Administratio... |
|
T81224 |
SALMF amide 2
|
|
|
|
SALMFamide 2, a neuropeptide S2 derived from the starfish Asterias rubens, plays a regulatory role in the eversion of the cardiac stomach in starfish [1]. |
|
T36148 |
13,14-dihydro-15-keto Prostaglandin F1α
|
13,14-dihydro-15-keto Prostaglandin F1α |
|
|
13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in v... |
|
TP1976 |
Oxyntomodulin
|
Oxyntomodulin (porcine, bovine) |
|
|
GLP-1 receptor agonist. Endogenous preproglucagon-derived neuropeptide that modulates feeding and metabolism. Also secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stom... |
|
T71980 |
Omeprazole acid
|
|
|
|
Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are... |
|
TP1232 |
Amylin, amide, rat
|
Amylin (rat) |
|
|
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con... |
|
T20914 |
Simethicone
|
Disflatyl,Simeticone,Phazyme |
Others
|
|
Simethicone (Disflatyl), an oral anti-foaming agent, can be used to reduce bloating, pain and discomfort caused by excess gas in the stomach or intestinal tract. |
|
T76107 |
Urease
|
|
|
|
Urease is produced by many types of bacteria and is an effective virulence factor for some pathogenic bacteria. Urease is also central to the metabolism and virulence of Helicobacter pylori, helping it colonize the stoma... |
|
T60493 |
Guaiacol Carbonate
|
|
|
|
Guaiacol Carbonate is an expectorant that acts via virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centers, then via peripherally again to the respiratory tract[1]. |
|
T75993 |
Pepsin A
|
|
|
|
Pepsin A, a primary gastric protease in both pigs and humans, functions similarly to minor gastric proteolytic enzymes. It plays a crucial role in the proteolysis of food proteins within the vertebrate stomach [1] [2]. |
|
T75992 |
Buforin II
|
|
|
|
Buforin II, a powerful antimicrobial peptide originating from Buforin I (a protein extracted from the Asian toad Bufo bufo gargarizans's stomach), exhibits broad-spectrum antimicrobial properties against both Gram-positi... |
|
T71055 |
Albendazole-d7
|
|
|
|
Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helmi... |
|
T36208 |
15(R)-Pinane Thromboxane A2
|
15(R)-Pinane Thromboxane A2 |
|
|
15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 . 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM). It does not affect gastric tone in isolated rat gastric fun... |
|
T62039 |
L-365260 hemihydrate
|
|
|
|
L-365260 hemihydrate is a selective, orally active non-peptide gastrin and brain cholecystokinin receptor (CCK-B) antagonist, demonstrating competitive interaction with guinea pig stomach gastrin and brain CCK receptors ... |
