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T10851 |
CMP-Sialic acid sodium salt
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CMP-Neu5Ac sodium salt |
Endogenous Metabolite
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CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is a variant inhibitor of UDP-GlcNAc 2-epimerase, the activated form of sialic acid, which is widely found in animals and is involved in the metabolism of organisms. |
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T10850 |
CMP-5
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Antiviral
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Histone Methyltransferase
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CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection. |
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T10850L |
CMP-5 2HCl
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Others
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CMP-5 2HCl is a anthelmintic agent. CMP-5 2HCl shows EC100 of 5μM against H. contortus in vitro. |
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T19243 |
CMP-5 hydrochloride
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Others
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CMP-5 hydrochloride is a potent and selective PRMT5 inhibitor, while displays no activity against PRMT1/4/7 enzymes. It selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. |
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T83629 |
Smurf-1 modulator CMP Example 20
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Smurf-1-IN-20 |
Others
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Smurf-1 modulator CMP Example 20 (Smurf-1-IN-20) is a potent Smurf-1 modulator. |
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T14987 |
CMP8
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Estrogen Receptor/ERR
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Estrogen/progestogen Receptor
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CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, res... |
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T27606 |
Indantadol HCl
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CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol |
MAO
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NMDAR
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Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor. |
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T3080 |
Pyridone 6
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Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I |
Tyrosine Kinases
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JAK
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Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM... |
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T73747 |
CMP-Sialic acid
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Others
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CMP-Sialic acid (CMP-Neu5Ac) serves as an allosteric inhibitor of UDP-GlcNAc 2-epimerase, a substrate for Golgi sialyltransferases, and is crucial for the biosynthesis of sialic acid and its conjugates [1]. |
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T27052 |
CMP3a
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CMP-3a,CMP 3a |
Others
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CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destab... |
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T84932 |
Cytarabine 5′-monophosphate
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ara-CMP |
Others
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Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibi... |
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T85002 |
Cytidine 3'-monophosphate
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3'-CMP |
Others
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Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2’,3’-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated... |
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T39750 |
CMP98
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PROTACs
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CMP98, a proteolysis targeting chimera (PROTAC), exhibits a lack of VHL degradation efficacy. It can function as a negative control compound in comparison to CM11. CMP98 comprises two von Hippel-Lindau ligands operating ... |
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T68490 |
CMPF
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Microtubule Associated
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CMPF is a microtubule protein inhibitor that can be used to study tumors. |
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T14989 |
CMPD101
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ROCK
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GRK
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PKC
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CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I... |
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T14988 |
CMPD1
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MAPK
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CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM). |
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TQ0114 |
CMPDA
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GluR
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CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor). |
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T25267 |
Cmpd 339509
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Cmpd339509,Cmpd-339509 |
Others
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Cmpd 339509 is a DprE1 inhibitor. DprE1 is an epimerase required for cell wall biosynthesis. |
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T70628 |
Cmpd-A
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Others
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Cmpd-A is a time-dependent CENP-E inhibitor with potent antitumor activity. Cmpd-A inhibits the ATPase activity of the CENP-E motor domain, acting as a time-dependent inhibitor with an ATP-competitive-like behavior. Cmpd... |
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T82702 |
CMPD167
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MRK-1 |
CCR
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CMPD167 (MRK-1) is a potent, orally active inhibitor of CCR5 with significant in vitro antiviral efficacy [1]. |
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T37293 |
CMPI hydrochloride
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Others
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Potent positive allosteric modulator of α4β2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for hα4β2 over hα3β2, hα3β4 and hα7. Inhibits (α4)2(β2)3, muscle-type and Torpedo nAChRs (IC50... |
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T74481 |
M7GpppCmpG
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Others
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m7GpppCmpG, a trinucleotide cap analogue and oligonucleotide, serves as a chemical tool for the production of RNA with either cap 0 or cap 1 structures, facilitating research and manufacturing processes involving these R... |
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T39771 |
NAChR agonist CMPI hydrochloride
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Others
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CMPI hydrochloride, a potent and selective nAChR agonist, functions as a positive allosteric modulator (PAM) specifically targeting the α4:α4 subunit interface of the nAChR. It enhances the response of the (α4)3(β2)2 nAC... |
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T8735 |
Sulbactum Sodium
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5'-CDP,Cytidine-5′-diphosphate |
Others
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Sulbactum Sodium (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK) |
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T83296 |
5-Azacytidine 5′-triphosphate
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Others
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5-Azacytidine 5′-triphosphate (5-aza-CMP), a cytidine analog, selectively inhibits the incorporation of [^3H]CTP into RNA during the DNA-dependent RNA polymerase reaction, while not affecting the incorporation of [^3H]UT... |
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T75395 |
Alpha-2-3,6-sialidase (BiNanH2)
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Others
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Alpha-2-3,6-sialidase (BiNanH2), a sialyltransferase commonly utilized in biochemical research, catalyzes the transfer of α-2,3/2,6-sialyl from CMP-Neu5Ac to galactoside acceptors [1]. |
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T74706 |
Vidutolimod
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Others
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Vidutolimod (CMP-001), a CpG-A oligodeoxynucleotide and Toll-like receptor 9 (TLR9) agonist, activates plasmacytoid dendritic cells (pDCs) and induces the release of interferon alpha (IFNα), initiating a series of anti-t... |
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T36300 |
Uridine-5’-monophosphate (sodium salt hydrate)
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Others
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Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during n... |
