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Search Results for " FC-1 "

ターゲット

阻害剤

天然化合物

1752

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T22508	3-CPMT	Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1	Dopamine Receptor
	3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.		Dopamine Receptor
T9543	Syk Inhibitor II hydrochloride		Others
	The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...		Others
T83063	Anti-IgG-Fc (Human)
	Anti-IgG-Fc (Human) is an antibody targeting the Fc region of human immunoglobulin G1 (IgG1) [1].
T80598	Davoceticept	CD80 vIgD-Fc,ALPN-202
	Davoceticept (ALPN-202; CD80 vIgD-Fc), a monoclonal antibody that targets CTLA-4, is comprised of the (1-107) fragment of CD80 fused to the IGHG1 Fc domain through a peptidyl linker. It is commonly produced in CHO (Chine...
T76936	Budigalimab
	Budigalimab (ABBV 181; PR 1648817), a humanized IgG1 monoclonal antibody, specifically targets the programmed cell death 1 (PD-1) receptor. It features an Fc mutation to decrease interactions with the Fc receptor, thereb...
T68225	Fc 11a-2
	Fc 11a-2, a benzimidazole compound, functions as an orally active, potent inhibitor of the NLRP3 inflammasome. It effectively hinders the NLRP3 inflammasome formation by blocking caspase-1 activation and consequently the...
T77182	Rimteravimab
	Rimteravimab (XVR011) is a bivalent VHH-Fc antibody that exhibits potent neutralizing activity, high stability, broad coverage, and has its Fc effector functions silenced, targeting the disease caused by SARS-CoV-2 [1].
T82502	Efaprinermin alfa	OMP-336B11
	Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].
T77133	Prolgolimab
	Prolgolimab (BCD-100), a human IgG1 anti-PD-1 monoclonal antibody featuring the Fc-silencing 'LALA' mutation, is utilized in advanced melanoma research [1].
T77039	Ipafricept
	Ipafricept (OMP-54F28; FZD8-Fc), a pioneering recombinant fusion protein, incorporates the extracellular segment of the human frizzled-8 receptor and the Fc fragment of human IgG1, targeting the Wnt ligand. It exhibits a...
T77175	Efruxifermin
	Efruxifermin, an Fc-FGF21 fusion protein consisting of a human IgG1 Fc domain linked to modified human FGF21, exhibits a prolonged half-life and enhanced receptor affinity compared to its native counterpart. It is utiliz...
T82499	Efmoroctocog alfa
	Efmoroctocog alfa, a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc), serves as a therapeutic agent for Hemophilia A research [1].
T63715	HIgG–hFc receptor-IN-1
	hIgG-hFc receptor-IN-1 is a human immunoglobulin G - human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor (IC50: 2 μM).
T77055	Lenercept
	Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].
T81624	Obexelimab	XmAb5871
	Obexelimab (XmAb5871) is a humanized Fc-engineered anti-CD19 antibody with enhanced affinity for FcγRIIb, utilized in the study of autoimmune diseases [1].
T82498	Eftansomatropin alfa
	Eftansomatropin alfa, an antibody that targets the growth hormone receptor (GSH), is a fusion protein comprising GH1 and the Fc region of IGHG4 [1].
T76839	Visilizumab
	Visilizumab, a humanized IgG2 monoclonal antibody with low Fc receptor binding affinity, targets the CD3 epsilon (CD3ε) subunit. It is utilized in research related to ulcerative colitis and Crohn's disease [1].
T76821	Ocaratuzumab
	Ocaratuzumab (AME 133v), an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, demonstrates enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) [1] [2] with a dissociation constant (Kd) of approximatel...
T78309	Telitacicept	RC18
	Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand), effectively impeding B lymphocyte proliferation. This com...
T81059	SWELYYPLRANL-NH2
	SWELYYPLRANL-NH2 is a dual antagonist of E-cadherin and N-cadherin, effectively inhibiting the binding of phage clones to both E-cad/Fc and N-cad/Fc chimeric proteins with IC50 values of 0.7 μM and 0.09 μM, respectively....
T82501	Efavaleukin alfa	AMG592
	Efavaleukin alfa (AMG592) is a human monoclonal antibody comprising the IGHG1 Fc fragment fused to interleukin-2 (IL-2). It is typically expressed in Chinese Hamster Ovary (CHO) cells [1].
T76925	Benufutamab
	Benufutamab (GEN1029), a death receptor 5 (DR5)-specific agonistic antibody, comprises a blend of two non-competing DR5-specific IgG1 antibodies with an E430G mutation in the Fc domain. This compound exhibits antitumor e...
T76689	Margetuximab
	Margetuximab (MGAH22) is a chimeric anti-HER2 monoclonal antibody with an optimized Fc domain, exhibiting an EC50 value of 39.33 ng/mL. It is utilized in the research of metastatic HER2-positive breast cancer [1].
T81605	Ontorpacept	TTI-621
	Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRPα fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor...
T76984	Tecaginlimab
	Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, is designed for the dual targeting and conditional activation of CD40 and 4-1BB, aiming to improve the priming and reactivation of tumor-specific immunity [1].
T77061	Letolizumab
	Letolizumab (BMS-986004), a monoclonal antibody directed at CD40L, is engineered to express a mutant IgG1 devoid of effector functions, such as Fc binding and complement fixation. It effectively reduces rejection and thr...
T78328	Efbemalenograstim alfa	F 627,Bineuta,Benegrastim
	Efbemalenograstim alfa (F 627) is a recombinant fusion protein comprising a long-acting dimeric granulocyte colony-stimulating factor (G-CSF) with two human G-CSF molecules connected via a peptide linker to a human immun...
T78249	Nipocalimab	M281
	Nipocalimab (M281), a fully human, recombinant, aglycosylated IgG1 monoclonal antibody, exhibits high-affinity binding to the Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6, characterized by its pic...
T80595	Conbercept	KH902	VEGFR
	Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR, linked to the Fc fragment of IGHG1. This monoclonal antibod...		VEGFR
T77906	Briobacept	BR 3FC
	Briobacept (BR 3FC), a selective human monoclonal antibody, targets BLyS (BAFF) to induce B-cell apoptosis and is a recombinant glycoprotein comprising two BLyS receptor (BR3) molecules fused to the Fc domain of human Ig...
T76715	Envafolimab
	Envafolimab (ASC 22; KN 035), a recombinant humanized single-domain anti-PD-L1 antibody, integrates the anti-PD-L1 domain with the Fc fragment of the human IgG1 antibody. It inhibits the PD-L1 and PD-1 interaction with a...
T78307	Catumaxomab
	Catumaxomab, a trifunctional IgG2 antibody with mouse and rat heavy and light chain components, targets human EpCAM and CD3 receptors. Its Fc region exhibits affinity for FcγRI (CD64), FcγRIIA (CD32a), and FcγRIII (CD16)...
T77034	Inbakicept	N-803
	Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). ...
T77139	Pavurutamab
	Pavurutamab (AMG-701) is a bispecific T-cell engager that targets CD3 and B-cell maturation antigens (BCMA), based on the extended half-life derived from Pacanalotamab. Its Fc region is engineered for improved pharmacoki...
T80762	XmAb 5592
	XmAb 5592 is a humanized, Fc-engineered antibody targeting HM1.24 with improved affinity for both FcγRIIIa and FcγRIIa receptors. It enhances lysis of HM1.24-specific multiple myeloma (MM) cells through both antibody-dep...
T77151	Cosibelimab
	Cosibelimab (CK-301; TG-1501) is a fully human, high-affinity monoclonal antibody that inhibits PD-L1 by preventing its interaction with PD-1. This compound, featuring a functional Fc domain, is effective in inducing ant...
T77110	Amivantamab
	Amivantamab (JNJ-61186372) is a bispecific antibody targeting EGFR-MET with immune anticancer properties. It prevents ligand binding, enhances receptor-antibody complex endocytosis and degradation, and triggers Fc-mediat...
T76911	Asunercept
	Asunercept (APG101; CAN008), a soluble CD95-Fc fusion protein, selectively targets and binds to CD95L, effectively disrupting CD95/CD95L signaling. It is utilized in research for treating glioblastoma multiforme (GBM), m...
T78302	Atacicept	TACI-Ig,TACI-Fc 5
	Atacicept (TACI-Ig), a recombinant fusion protein, comprises the extracellular, ligand-binding segment of the TACI receptor fused with the Fc portion of human IgG. It functions by inhibiting B cell activation through bin...
T80880	Valziflocept	BAX1810,TAK-752
	Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor designed to act as a "decoy" or "scavenger" by targeting Fc and FcγR, binding and neutralizing pathogenic IgG. Its utility lies in mitigatin...
T81058	SWELYYPLRANL-NH2 TFA
	SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 μM and 0.09 μM, respectively...
T77037	Insulin efsitora alfa
	Insulin efsitora alfa (LY-3209590) is a selective insulin receptor (IR) agonist, comprising a fusion protein that integrates human IR agonists with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2), and ha...
T77173	Eflepedocokin alfa
	Eflepedocokin alfa is a recombinant fusion protein that exhibits cell protective activity by comprising human IL-22 fused with the human IgG2-Fc domain. This compound activates the IL-22/IL-22R -mediated signal transduct...
T76980	Tidutamab
	Tidutamab (XmAb-18087) is a bispecific antibody (bsAb) that is both humanized and optimized for affinity, targeting the SSTR2 and CD3 domains to bind to the somatostatin receptor 2 (SSTR2) and T cells, respectively. It f...
T81917	Lorukafusp alfa	hu14.18-IL2,EMD 273063,14.18 mAb
	Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine composed of the humanized 14.18 anti-GD2 monoclonal antibody (mAb) connected to interleukin-2 (IL210). It exerts its anti-tumor effects [1] through the induct...
T76716	Cadonilimab
	Cadonilimab (AK104) is a humanized antibody engineered from the IgG1 scaffold and targets PD1/CTLA4. It is utilized in the research of metastatic cervical cancer [1] [2].
T76905	Anbenitamab
	Anbenitamab (KN-026) is a bispecific antibody that targets extracellular domains II and IV of human HER2, blocking both ligand-dependent and independent signaling pathways. Its IgG1 Fc fragment activates FcRγIIIa, trigge...
T78325	Orilanolimab	SYNT001
	Orilanolimab (SYNT001) is a humanized, de-immunized monoclonal antibody that inhibits the FcRn-IgG interaction, thereby disrupting IgG homeostasis and impeding FcRn-mediated adaptive immune responses, as well as related ...

Compounds

3-CPMT

T22508

Synonym: Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1

Target: Dopamine Receptor

Syk Inhibitor II hydrochloride

Synonym: CD80 vIgD-Fc,ALPN-202

hIgG–hFc receptor-IN-1

Efbemalenograstim alfa

T78328

Synonym: F 627,Bineuta,Benegrastim

Synonym: TACI-Ig,TACI-Fc 5

Target:

Valziflocept

T80880

Synonym: BAX1810,TAK-752

Insulin efsitora alfa

Synonym: hu14.18-IL2,EMD 273063,14.18 mAb

カタログ番号	製品名	別名	ターゲット
T3S1591	Notoginsenoside Fc		Others , Autophagy
	1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.		Others , Autophagy

天然物製品

Notoginsenoside Fc

T3S1591

Synonym:

Target: Others, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02694	IgG2a Protein, Mouse, Recombinant	Mouse	HEK293
	IgG2a Protein, Mouse, Recombinant is expressed in HEK293 cells.
TMPY-00800	CD32B/Fcgr2b Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD32B/Fcgr2b Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 21.7 kDa. Accession number: A0A0B4J1E6
TMPY-05188	IgG2a Protein, Mouse, Recombinant, Biotinylated	Mouse	HEK293
	IgG2a Protein, Mouse, Recombinant, Biotinylated is expressed in HEK293. The predicted molecular weight is 26.4 kDa. Accession number: P01863
TMPJ-00610	HFcRL1 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (...
TMPK-00240	Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (C...
TMPK-00241	Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (C...
TMPY-01664	FcRH1/FCRL1 Protein, Human, Recombinant (His)	Human	HEK293
	Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which ...
TMPJ-00419	CD16b Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like...
TMPY-03075	FcRH1/FCRL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which ...
TMPY-01986	CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 with His and AVI tag. The predicted molecular weight is 23.9 kDa. Accession number: A0A0B4J1E6
TMPY-04272	FcRH2/FCRL2 Protein, Human, Recombinant (His)	Human	HEK293
	Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation ...
TMPY-06881	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated	Human	HEK293
	CLEC12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycop...
TMPY-04871	HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc)	HIV	HEK293
	HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 with Fc tag. The predicted molecular weight is 99.9 kDa. Accession number: O12164
TMPY-00952	Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA Protein (His & Fc)	H5N1	HEK293
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two...
TMPY-06499	CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His)	Rhesus	HEK293
	CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 with Fc-Flag,Fc-His tag. The predicted molecular weight is 76.63 kDa. Accession number: F6WI60-1
TMPY-01408	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc)	HIV	HEK293
	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 with Fc tag. The predicted molecular weight is 98 kDa.
TMPY-00426	HIV-1 (group P, strain RBF168) gp140 Protein (hFc)	HIV	HEK293
	HIV-1 (group P, strain RBF168) gp140 Protein (hFc) is expressed in HEK293 with Fc tag. The predicted molecular weight is 99.4 kDa. Accession number: D0VTQ8
TMPY-00054	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)	CyCMV	HEK293
	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 with Fc tag. The predicted molecular weight is 102.5 kDa. Accession number: E7DB34
TMPY-00425	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)	HIV	HEK293
	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 with Fc tag. The predicted molecular weight is 97.4 kDa. Accession number: P90249
TMPJ-00425	NCR1 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Natural cytotoxicity triggering receptor 1(NKp46/NCR1) is a single-pass type I membrane protein. It consists of two extracellular Ig-like domains followed by a short stalk region, a transmembrane domain containing a posi...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPY-02722	SCN3B Protein, Human, Recombinant (hFc)	Human	HEK293
	SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPY-02976	SCN3B Protein, Human, Recombinant (His)	Human	HEK293
	SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-01023	CD38 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05239	HER2/ERBB2 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-05364	CD8 alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01226	CD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01050	Cadherin 6/CDH6 Protein, Human, Recombinant (His)	Human	HEK293
	Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc)	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01938	CD98 Protein, Human, Recombinant (His)	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His)	Human	HEK293
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01912	Cadherin 17/CDH17 Protein, Human, Recombinant (His)	Human	HEK293
	Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-01851	CD73 Protein, Human, Recombinant (His)	Human	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-05319	BCMA/TNFRSF17 Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02019	CD59 Protein, Human, Recombinant (His)	Human	HEK293
	CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099	CD63 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01608	Decorin Protein, Human, Recombinant (His)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
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