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カタログ番号 | 製品名 | 別名 | ターゲット |
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T22033 | ARC 239 dihydrochloride | Norepinephrine | |
ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively). | |||
T12597 | 5-HT2 antagonist 1 | 5-HT Receptor | |
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity. | |||
T26923 | Bunazosin Hydrochloride | E 1015,E643,E-1015,E-643,E 643 | Adrenergic Receptor |
Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug. | |||
T30846 | CGP-20712 | UNII-SIO2UEZ19H,CGP 20712 | Adrenergic Receptor |
CGP-20712 is a selective β 1-adrenoceptor antagonist with an IC50 of 0.7 nM. | |||
T11726 | JP1302 dihydrochloride | Adrenergic Receptor | |
JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Ki (binding affinity) value of 28 nM and a Kb value (antagonist activity) of 16 nM. | |||
T28267 | ORM-10921 | ORM10921,ORM 10921 | Adrenergic Receptor |
ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies. | |||
T11286 | Fiduxosin | A 185980.1,ABT 980 | Adrenergic Receptor |
T11015 | Midaglizole hydrochloride | (±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128 | Adrenergic Receptor |
Midaglizole hydrochloride ((±)-DG5128) (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times higher than that of α1-adrenocepto... | |||
T30027 | Amosulalol | Adrenergic Receptor | |
Amosulalol is a combined alpha and beta adrenoceptor antagonist. | |||
T61535 | Neldazosin | Adrenergic Receptor | |
Neldazosin is used as a potent α1-adrenoceptor antagonist. | |||
T9220 | Naftopidil hydrochloride | 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,KT-611 hydrochloride,BM-15275 hydrochloride | Adrenergic Receptor |
Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respective... | |||
T0088 | Urapidil hydrochloride | Urapidil HCl | 5-HT Receptor , Adrenergic Receptor |
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist. | |||
T28922 | Taprizosin | Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003 | Adrenergic Receptor |
Taprizosin(UK-338003) is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia. | |||
T20898 | (R)-Propranolol hydrochloride | Dexpropranolol hydrochloride,(R)-(+)-Propranolol | Adrenergic Receptor |
(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag... | |||
T16431 | Pamatolol | Adrenergic Receptor | |
T7079 | Batefenterol | GSK961081,TD-5959 | Adrenergic Receptor , AChR |
Batefenterol (TD-5959) (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/1.3/3.7 nM). | |||
T9762 | Upidosin | SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739 | Adrenergic Receptor |
Upidosin (SB-216469) is a potential uroselective α1-adrenoceptor antagonist, α1a subtype Ki=0.34 nM, α1b subtype Ki=3.9 nM, α1d subtype Ki=1.5 nM, α2-adrenoceptor Ki=33.3 nM. | |||
T16798 | RS 17053 hydrochloride | RS-17053 | Others , Adrenergic Receptor |
RS 17053 hydrochloride is a potent and selective antagonist of α1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. | |||
T4526 | Piperoxan hydrochloride | dl-Piperoxan hydrochloride,Benodaine hydrochloride | Adrenergic Receptor |
Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. | |||
T12643 | (R)-Terazosin | Adrenergic Receptor | |
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively). | |||
T5028 | Landiolol hydrochloride | ONO-1101 hydrochloride | Adrenergic Receptor |
Landiolol hydrochloride (ONO-1101 hydrochloride) is an ultra-short-acting β1 selective adrenoceptor antagonist. | |||
T15688 | L-771688 | SNAP 6383 | Adrenergic Receptor |
L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benign prostatic hyperplasia. | |||
T6701 | Terazosin hydrochloride dihydrate | Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate | Adrenergic Receptor |
Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH). | |||
T0165 | Urapidil | Mediatensyl,Ebrantil,Eupressyl | 5-HT Receptor , Adrenergic Receptor |
Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist. | |||
T21640 | Talinolol | Adrenergic Receptor | |
(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity. | |||
T8143 | Bevantolol hydrochloride | NC-1400 hydrochloride | Calcium Channel , Adrenergic Receptor |
Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension. | |||
T77565 | Fluparoxan hydrochloride | Adrenergic Receptor | |
Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases. | |||
T62893 | SM-2470 | Adrenergic Receptor | |
SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity that decreases anterior ganglionic adrenal nerve activity and aortic descending nerve activity.SM-2470 has hypocholesterolemic activity and inhibits... | |||
T7728 | ACEPROMAZINE MALEATE | Dopamine Receptor | |
ACEPROMAZINE MALEATE is a dopamine receptor antagonist | |||
T23232 | Remoxipride hydrochloride | Remoxipride Hydrochloride Anhydrous,Roxiam,(S)-Remoxipride Hydrochloride | Dopamine Receptor |
Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, >100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoceptor. | |||
T25828 | Monatepil maleate | AJ2615 maleate,AJ-2615 maleate,AJ 2615 maleate | Calcium Channel , Adrenergic Receptor , Acyltransferase |
Monatepil maleate (AJ-2615 maleate) is an orally active Ca2+-channel and α1-adrenoceptor antagonist and non-competitive heparanoyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with antihypertensive activity.Mo... | |||
T0115 | Idazoxan hydrochloride | RX 781094 | Adrenergic Receptor , Imidazoline Receptor |
Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity. | |||
T14490 | Talipexole dihydrochloride | Domnin,B-HT 920 dihydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ... | |||
T22882 | JP1302 | Adrenergic Receptor | |
JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been u... | |||
T22905 | L748337 | L-748,337 | Adrenergic Receptor |
L748337 is a competitive and potent β3-adrenoceptor antagonist that inhibits the action of β3-, β2-, and β1-adrenoceptors, activates MAPK signaling, promotes phosphorylation of Erk1/2, and inhibits the protective effects... | |||
T8580 | Bupranolol | Adrenergic Receptor | |
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. | |||
T63980 | BODIPY FL prazosin | ||
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist that acts on α1a-AR (Ki: 14.5 nM) and α1b-AR (Ki: 43.3 nM). BODIPY FL prazosin can be used for the study of subcellular localization differences in α1-adrenoce... | |||
T6600 | Naftopidil dihydrochloride | KT-611,KT-611 2HCl,Naftopidil DiHCl | 5-HT Receptor , Adrenergic Receptor |
Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. | |||
T68138 | Saterinone | Adrenergic Receptor , PDE | |
Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic hear... | |||
T0696 | Naftopidil | KT-611,BM-15275 | Adrenergic Receptor |
Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker. | |||
T6765 | Atipamezole hydrochloride | MPV-1248 hydrochloride,Antisedan | Adrenergic Receptor |
Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride (MPV-1248 hydrochloride) is hydrochloride form of atipa... | |||
T6766 | Atipamezole | Antisedan,MPV 1248 | Adrenergic Receptor |
Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. | |||
T1158 | Phenoxybenzamine hydrochloride | NCI-c01661,NSC 37448,Phenoxybenzamine HCl | CaMK , Adrenergic Receptor |
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... | |||
T23374 | SNAP 5089 | Others | |
α1A-adrenoceptor antagonist | |||
T22699 | Cyanopindolol hemifumarate | Others | |
5-HT1A/1B antagonist and β-adrenoceptor antagonist | |||
T23366 | SKF 86466 hydrochloride | Others | |
SKF 86466 hydrochloride is an α2-adrenoceptor antagonist. | |||
T24012 | Domesticine, (-)- | L-Domesticine | Others |
Domesticine, (-)- is an antagonist of alpha-1D-adrenoceptor. | |||
T22861 | Imiloxan hydrochloride | Others | |
Imiloxan hydrochloride is an α2-adrenoceptor antagonist. | |||
T26134 | RS 15385-197 | RS-15385-197,RS15385-197 | Others |
RS 15385-197 is a selective alpha 2-adrenoceptor antagonist. | |||
T22760 | Efaroxan hydrochloride | Others | |
α2 adrenoceptor antagonist and imidazoline I1 receptor ligand |
カタログ番号 | 製品名 | 別名 | ターゲット |
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TN3393 | Alpha-Yohimbine | 5-HT Receptor | |
Alpha-Yohimbine is a 5-HT1A receptor agonist, it is strong selective 2-adrenoceptor antagonist. Alpha-Yohimbine possess aphrodisiac effect. | |||
TN1577 | Dicentrine | Others | |
Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain. | |||
TN2267 | Tetrahydroalstonine | Adrenergic Receptor | |
Tetrahydroalstonine is an indole alkaloid extracted from the fruit of Rhazya stricta and is a selective α2-adrenoceptor antagonist. tetrahydroalstonine has shown antipsychotic activity in Rauwolfia tetraphylla. | |||
TN7042 | N-methyltyramine | Adrenergic Receptor | |
N-methyltyramine is an alkaloid isolated from the leguminous plant Acacia grandiflora.It is an α2-adrenoceptor antagonist that regulates adrenergic receptors through enzymatic adrenergic synthesis.It is used in the study... |