|
T22459 |
Xanthinol Nicotinate
|
Angioamin,Complamin |
Others
|
|
Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy. |
|
T0042 |
Xylometazoline hydrochloride
|
Xylometazoline HCl |
Adrenergic Receptor
|
|
Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant. |
|
T1275 |
Phentolamine mesylate
|
Phentolamine methanesulfonate,Phentolamine mesilate |
Adrenergic Receptor
|
|
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS... |
|
T1615 |
Irbesartan
|
SR-47436,BMS-186295 |
Apoptosis
,
RAAS
|
|
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist. |
|
T21231 |
Almotriptan
|
LAS 31416 |
5-HT Receptor
|
|
Almotriptan (LAS 31416) is a 5-HT1B/1D-receptor agonist used to treat migraine.Almotriptan is a triptan drug for treatment of migraine headaches.Binding of the drug to the receptor leads to vasoconstriction of the crania... |
|
T0504 |
Cyclandelate
|
BS 572,3,5,5-Trimethylcyclohexyl mandelate |
Acyltransferase
|
|
Cyclandelate (BS 572), a direct-acting smooth muscle relaxant, is used to dilate blood vessels. |
|
T6863 |
Isosorbide Mononitrate
|
Isosorbide-5-mononitrate,Imdur,Mononit,Corangin,Monoket,Elantan |
Others
,
Autophagy
|
|
Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure. |
|
T4509 |
Inositol nicotinate
|
Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,Dilexpal,Inositol hexanicotinate |
Others
|
|
Inositol nicotinate (Mesotal) has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis. |
|
T12478L |
Pinacidil
|
S 1230,P 1134,S-1230,P-1134,P1134 |
Potassium Channel
|
|
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention. |
|
T5161 |
Gadodiamide
|
|
Others
|
|
Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels. |
|
T3996 |
Dapiprazole Hydrochloride
|
Glamidolo Hydrochloride,Reversil Hydrochloride |
Adrenergic Receptor
|
|
Dapiprazole Hydrochloride (Glamidolo Hydrochloride) is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointes... |
|
T19512 |
Phalloidin
|
|
Others
|
|
Phalloidin, a bicyclic heptapeptide found in Gooseberry, is involved in F-actin staining. Phalloidin is a compound that irreversibly polymerizes actin into microfilaments.Phalloidin interferes with cell motility and grow... |
|
T0397 |
Tetrahydrozoline
|
Tetryzolin,Tetryzoline |
Adrenergic Receptor
|
|
Tetrahydrozoline (Tetryzoline), an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular irritants. |
|
T4287 |
Succinobucol
|
Probucol monosuccinate,AGI-1067 |
Antioxidant
,
Reactive Oxygen Species
|
|
Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ... |
|
T4506 |
Gadopentetate dimeglumine
|
Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,Gadopentetic acid dimeglumine salt |
Others
|
|
Gadopentetate dimeglumine (Gd-DTPA), an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more cl... |
|
T21447 |
Tolazoline
|
Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin |
Adrenergic Receptor
|
|
Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th... |
|
TP1277 |
Bradykinin
|
|
Endogenous Metabolite
,
Bradykinin Receptor
|
|
Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol... |
|
T12315 |
OR-1896
|
|
PDE
|
|
OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood ve... |
|
T37436 |
C12-Ceramide
|
N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine |
|
|
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activi... |
|
T0075 |
Nicorandil
|
SG-75 |
Potassium Channel
|
|
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b... |
|
T6602 |
Naratriptan hydrochloride
|
Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride |
5-HT Receptor
|
|
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc... |
|
T1056 |
Isoprenaline hydrochloride
|
NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl |
PI3K
,
Endogenous Metabolite
,
Adrenergic Receptor
,
PDE
|
|
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties. |
|
T19478 |
Nicotinoyl cyclandelate
|
RV 12128 |
Others
|
|
Nicotinoyl cyclandelate can effectively reduce blood pressure in the femoral artery and perfusion pressure in cerebral blood vessels. |
|
T25173 |
Bradykinin potentiator-5
|
BPP-5a\,BPP 5a\,BPP5a\ |
|
|
Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall. |
|
T31857 |
Fosbretabulin [free base]
|
Fosbretabulin,Combretastatin A-4,CA4DP |
|
|
Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels. |
|
T68478 |
Arnolol
|
|
|
|
Arnolol is a beta blocker. Beta blockers block the hormone epinephrine, also known as adrenaline. This causes the heart to beat more slowly and with less force, thereby reducing blood pressure. Beta blockers also help bl... |
|
T25670 |
Lercanidipine. (R)-
|
(-)-Lercanidipine,(R)-Lercanidipine |
|
|
Lercanidipine. (R)- is an enantiomer of antihypertensive drugs Lercanidipine. Lercanidipine acts by blocking L-type calcium channels, allowing relaxation and opening of blood vessels. |
|
T68367 |
Amlodipine orotate
|
|
|
|
Amlodipine orotate is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers ... |
|
T71583 |
Amlodipine hydrochloride, (R)-
|
|
|
|
Amlodipine hydrochloride, (R)-, is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vess... |
|
T69813 |
AZD-6126
|
|
|
|
AZD6126, also known as ANG-453, a water-soluble phosphate prodrug of N-acetylcolchinol with potential antiangiogenesis and antineoplastic activities. AZD-6126 is an angiogenesis inhibitor and tubulin inhibitor potentiall... |
|
T61729 |
Terazosin
|
|
|
|
Terazosin, a quinazoline derivative, is an orally active and competitive antagonist of α1-adrenoceptors. Its mechanism of action involves relaxing blood vessels and promoting bladder opening. Terazosin exhibits therapeut... |
|
T3443 |
Argiprestocin
|
Arginine vasotocin |
Others
|
|
Argiprestocin (Arginine vasotocin) , also called antidiuretic hormone that plays a key role in maintaining osmolality. It is a neurohypophysial hormone found in most mammals. Drugs used to cause constriction of the bloo... |
|
T60263 |
Povafonidine
|
|
|
|
Povafonidine (PGE-6201204) is a potent alpha-2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion which can be used for nasal congestion research [1]. |
|
T31396 |
Dexbrompheniramine maleate
|
D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral |
|
|
Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the g... |
|
T1120L2 |
Dacarbazine citrate
|
DTIC citrate |
|
|
Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Sof... |
|
T69452 |
AG-13958 monohydrochloride
|
|
|
|
AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic bl... |
|
T9922 |
Matuzumab
|
|
EGFR
|
|
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR frequently associated with the growth of blood vessels in malignancy facilitating tumor growth and survival. |
|
T76550 |
CooP
|
|
|
|
CooP, a linear glioblastoma-targeting nonapeptide, interacts with the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) found in glioblastoma cells and their associated blood vessels. This interaction... |
|
T83681 |
IRBP (1-20) (human, rat) TFA
|
IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20) |
|
|
Interphotoreceptor retinoid-binding protein (1-20) (IRBP1-20), a dodecapeptide fragment of retinoid-binding protein 3, plays a crucial role in pigment regeneration by facilitating the transport of retinol and retinal bet... |
|
T67442 |
CGP-53716
|
|
|
|
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i... |
