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T5329 |
Trandolapril
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Angiotensin-converting Enzyme (ACE)
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Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. |
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T1462 |
Captopril
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SQ 14225,SQ-14534,SA333 |
RAAS
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Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure. |
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T0342 |
Carvedilol phosphate hemihydrate
|
Carvedilol phosphate,BM 14190 (phosphate hemihydrate) |
VEGFR
,
Others
,
Potassium Channel
,
LDL
,
Integrin
,
Gap Junction Protein
,
NADPH
,
Adrenergic Receptor
,
Autophagy
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom... |
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T0154 |
Nebivolol hydrochloride
|
R 065824 hydrochloride,Nebivolol HCl,R-65824 |
Apoptosis
,
Adrenergic Receptor
|
|
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us... |
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T33600L |
(Rac)-Naxifylline
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(Rac)-Naxifylline（(Rac)-166374-49-8） |
Others
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(Rac)-Naxifylline may be used to study congestive heart failure. |
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T27596 |
Imazodan hydrochloride
|
CI914 HCl,CI-914 HCl,CI 914 HCl,Imazodan HCl |
PDE
|
|
Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure. |
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T6595 |
Moexipril hydrochloride
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Moexipril HCl,RS-10085,SPM 925,CI-925 |
Apoptosis
,
RAAS
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Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure. |
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T1182 |
Levocarnitine propionate hydrochloride
|
Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261 |
Histamine Receptor
|
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Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases. |
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T0805 |
Quinapril hydrochloride
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CI-906,PD-109452-2,Quinapril HCl |
RAAS
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Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie... |
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T16782 |
Rolofylline
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KW-3902,MK-7418,KF-15372 |
Adenosine Receptor
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Rolofylline (KW-3902) is a selective adenosine A1 receptor antagonist used in the study of acute congestive heart failure and renal dysfunction, and in the study of neurodegenerative disorders. |
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T27119L |
(Rac)-Daglutril
|
SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid |
Others
|
|
(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ... |
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T25984 |
(±)-Prenalterol
|
H80/62,H-80/62,H 80/62 |
Adrenergic Receptor
|
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(±)-Prenalterol (H 80/62) is a new cardioselective positive inotropic compound that is an agonist of beta-2- and beta-1-adrenergic receptors and can be used to study chronic congestive heart failure. |
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T8462 |
Enoximone
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PDE
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Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure. |
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T2530 |
Levosimendan
|
OR1259,OR1855 |
Potassium Channel
,
PDE
,
Carbonic Anhydrase
,
Autophagy
|
|
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without ... |
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T16444 |
PD-118057
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|
Potassium Channel
,
HER
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PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential ... |
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T35336 |
Furosemide sodium
|
Frusemide Sodium,Lasix |
Na-K-Cl cotransporter
|
|
Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity ... |
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T28191 |
NP-252
|
NP252 |
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NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure. |
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T13599 |
Benzofurodil
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CB4091,Benfurodil,Eudilat |
Others
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Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure. |
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T33805 |
OPC 18692
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OPC-18692,OPC18692 |
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OPC 18692 is a metabolite of Vesnarinone, a positive inotropic drug developed for congestive heart failure. |
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T29995 |
Amisometradine
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Aminoisometradin,Aminoisometradine,Rolicton |
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Amisometradine is a diuretic which may be used in the treatment of congestive heart failure. |
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T30501 |
BMS-193884
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BMS193884,BMS 193884 |
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BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension. |
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T33711 |
Nolomirole
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CHF1025,CHF-1025,CHF 1025 |
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Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine. |
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T28309 |
PD 113413
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PD-113413,PD113413 |
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PD 113413 is a metabolite of quinapril, an angiotensin-converting enzyme inhibitor for the treatment of hypertension and congestive heart failure. |
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T26423 |
A 58365 B
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A-58365 B,A58365 B |
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A 58365 B, an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus, is used for the treatment of congestive heart failure and hypertension. |
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T26422 |
A 58365 A
|
A 58365A,A58365A,A-58365A |
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A 58365 A, an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus, is used for the treatment of congestive heart failure and hypertension. |
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T28485 |
Quinaprilat hydrate
|
Quinaprilat,CI-928,CI 928,BRN 5653070 |
|
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Quinaprilat is the active metabolite of quinapril, an angiotensin-converting enzyme inhibitor used in the treatment of congestive heart failure and hypertension. |
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T30956 |
CK 3197
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CK3197,CK-3197 |
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CK 3197 is a selective positive inotropic agent for the treatment of congestive heart failure. It has hemodynamic and myocardial energetic effects. |
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T30955 |
CK 2289
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CK-2289,CK2289 |
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CK 2289 is an inhibitor of type III cyclic 3'5' -adenosine monophosphate phosphodiesterase with potential use in the treatment of congestive heart failure. |
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T11609 |
ICI 153110
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Others
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T34107 |
Polythiazide
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P2525,NSC-108161,NSC 108161,P-2525,NSC108161 |
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Polythiazide (NSC-108161, P-2525) is used to treat fluid retention (edema) caused by a variety of causes, including congestive heart failure, severe liver disease (cirrhosis), kidney disease, or steroid or hormonal medic... |
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T6444 |
Cilazapril Monohydrate
|
Ro 31-2848 monohydrate,Justor |
RAAS
|
|
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
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T33600 |
Naxifylline
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CVT 124,CVT-124,CVT124,BG9719 |
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Naxifylline is an A1 adenosine receptor antagonist that promotes urine volume to prevent the decline in renal function observed during diuretic therapy for the treatment of edema associated with congestive heart failure. |
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T15434 |
GSK2798745
|
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TRP/TRPV Channel
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GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated wi... |
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T71205 |
Fosinopril-d7 sodium salt
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|
|
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Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administratio... |
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T13195 |
Trandolapril D5
|
RU44570 D5 |
Others
|
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Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF). |
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T68600 |
Enoximone sulfoxide
|
|
|
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Enoximone sulfoxide is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation... |
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T80891 |
Urodilatin
|
|
|
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Urodilatin, an analogue of ANF-(99-126), serves as a diuretic-natriuretic regulatory peptide with applications in the study of acute renal failure, congestive heart failure, and bronchial asthma, among other conditions [... |
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T62992 |
Trandolapril hydrochloride
|
|
|
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Trandolapril (RU44570) hydrochloride is a non-mercapto precursor compound that is hydrolysed to active diacetyl (Trandolapril hydrochlorideat). Trandolapril hydrochloride has been studied in hypertension and congestive h... |
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T33851 |
Ozolinone
|
W 3282,W3282,W-3282 |
|
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Ozolinone is an active metabolite of etozoline which acts as a loop diuretic --- a diuretic that acts at the ascending limb of the loop of Henle in the kidney. Loop diuretics are primarily used in medicine to treat hyper... |
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T63425 |
Spirapril hydrochloride
|
|
|
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Spirapril (SCH 33844) hydrochloride is a potent inhibitor of angiotensin-converting enzyme (ACE) and is an orally active prodrug of spiripril. Spirapril hydrochloride can be used to study hypertension and congestive hear... |
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T79913 |
GRK2 Inhibitor 2
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GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances β-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293 cells. It is utilized in congestive heart failure (HF) resear... |
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T76357 |
Neuropeptide Y (18-36) (porcine)
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Neuropeptide Y (18-36) (porcine) acts as a competitive antagonist of the neuropeptide Y (NPY) cardiac receptor, effectively blocking the attachment of I-NPY to cardiac ventricular membranes. Its action is concentration-d... |
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T70990 |
ADMA-d6
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NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synt... |
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T60383 |
Captopril hydrochloride
|
|
|
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Captopril (SQ 14225) hydrochloride is an antihypertensive agent that is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC 50 of 0.025 μM and has been widely used for rese... |
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T68616 |
Pentoprilat
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|
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Pentoprilat is a member of a series of l-glutarylindoline-2(S)-carboxylic acid derivatives. Pentopril was evaluated as an inhibitor of a cell-free preparation of angiotensin-converting enzyme (ACE) isolated from rabbit l... |
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T69600 |
Spermidine-d6
|
|
|
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Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µ... |
