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Search Results for " glaucoma "

ターゲット

99

阻害剤

6

天然化合物

9

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T8899 Metipranolol Adrenergic Receptor
Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc...
T6781 Benzenesulfonamide Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide Carbonic Anhydrase
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.
T14960 Chroman 1 ROCK
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM).
T6469 Dichlorphenamide Diclofenamide,Daranide,Antidrasi Carbonic Anhydrase
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
T0142 Brinzolamide AL-4862 Carbonic Anhydrase
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
T0106 Methazolamide L584601,CL 8490 Carbonic Anhydrase
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
T23782 Benzolamide CL-11366,W 1803,CL 11366,CL11366,W-1803 Carbonic Anhydrase
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
T0445 Promethazine Proazamine,Diphergan CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
T20743 TG-46 TG46,TG 46 FLT , JAK
TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma.
T7213 Demecarium bromide BC-48 AChE
Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
T6408 Betaxolol Kerlone,SL 75212,Betoptic Adrenergic Receptor
Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
T16731 Rentiapril racemate (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril Angiotensin-converting Enzyme (ACE)
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
T16132 MRE3008F20 cAMP , Adenosine Receptor
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9
T6422 Brimonidine Tartrate AGN190342 tartrate,304 tartrate,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate Adrenergic Receptor
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hyperten...
T8580 Bupranolol Adrenergic Receptor
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T0103 Dipivefrin hydrochloride Dipivefrin HCL Adrenergic Receptor , AChR
Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.
T34914 Trabodenoson INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875 Adenosine Receptor
Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.
T2538 Bimatoprost AGN 192024 Prostaglandin Receptor
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.
T71138L Binospirone MDL 73005EF 5-HT Receptor
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction.
T6565 Levobetaxolol hydrochloride Betaxon,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl Adrenergic Receptor
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma.
T5841 Travoprost Flu-Ipr,Fluprostenol isopropyl ester,AL6221 Prostaglandin Receptor
Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.
T20157 Brimonidine AGN190342,Bromoxidine,AGN 190342,AGN-190342 Adrenergic Receptor
Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P. It is used to treat open-angle glaucoma or ocular hypertension
T9847 TLC2976-0103
ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction [1].
T31731 Evodenoson DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313 Adenosine Receptor
Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumo...
T19870 Aceclidine 3-Acetoxyquinuclidine,1-azabicyclo[2.2.2]octan-3-yl acetate,NSC657843,3-quinuclidinyl acetate,NSC-657843,Glaucostat,NSC 657843,Quinuclidin-3-yl acetate AChR
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure.
T60351 Acetazolamide sodium OT-302 sodium Carbonic Anhydrase
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and alt...
T76828 Sonepcizumab LT 1009 LPL Receptor
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi...
T3174 Taprenepag CP-544326 Prostaglandin Receptor
Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
T21371 Apraclonidine hydrochloride Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum Adrenergic Receptor
Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco...
T15719 Latanoprostene bunod LBN,NCX116 Others
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o...
T77513 2-Chlorophenylboronic acid FAAH
2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new drugs.2-Chlorophenylboronic acid has an inhibitory effect o...
T31600 Echothiophate Iodide Phospholine iodide,Ecostigmini Sodidum,Iodide, Echothiophate,Echodide,Ecothiophate iodide
Echothiophate iodide is an effective long-acting cholinesterase inhibitor for the treatment of glaucoma.
T0103L Dipivefrin K 30081,K-30081,Dipivefrinum,Dipivefrina,K30081
Dipivefrin is a prodrug of epinephrine, and is used to treat open-angle glaucoma.
T32699 Levobunolol Levobunololum,Liquifilm,AK-Beta,Betegan
Levobunolol is a nonselective beta-blocker. It is used topically to treat glaucoma.
T27518 GW-876167 PRX-00933,PNU-183933,GW876167,BVT933,BVT-933
GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma.
T71250 NCX-274
NCX-274 is a ROCK inhibitor and NO-donating anti-glaucoma agent
T71249 NCX-278
NCX-278 is a ROCK inhibitor and NO-donating anti-glaucoma agent.
T28457 Proxodolol hydrochloride
Proxodolol, a β-adrenergic receptor antagonist, is used potentially for the treatment of glaucoma, hypertension and angina.
T20644 Unoprostone isopropyl UF021,Rescula,UF-021,UF 021
Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.
T29708 Aganepag isopropyl AGN-210961,AGN 210961,AGN210961
Aganepag isopropyl can be used to treat Glaucoma.
T29811 AL-16049 AL 16049,AL16049
AL-16049 is an FP-Class prostaglandin analog which may be useful in the treatment of glaucoma and ocular hypertension.
T71333 Iganidipine HCl
NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for the treatment of glaucoma.
T34644 Simenepag isopropyl AGN210669,AGN-210669,AGN 210669
Simenepag isopropyl can be used for the treatment of Glaucoma, Ocular Hypertension.
T22743 Dorzolamide Others
Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
T19528 Propionylcarnitine Propionyl carnitine Others
Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu
T27739 KR-31378 MSH1001,DNB 001,DNB-001,DNB001,MSH-1001,KR31378
KR-31378, a K(ATP) channel activator, is used potentially for the treatment of ocular hypertension and glaucoma.
T31054 CP-432 CP432,CP734432,CP 734432,CP-734432
CP-432 (CP-734432) is an EP4 prostaglandin agonist for the treatment of glaucoma and ocular hypertension.
T13955 Unoprostone Others
Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.
T75031 Pirnabine
Pirnabine, a cannabinoid receptor ligand, is utilized in glaucoma research [1].
T68756 Naboctate
Naboctate is a synthetic cannabinoid receptor agonist. It has antiemetic, sedative, anxiolytic and anti-glaucoma properties.

Compounds

Metipranolol
T8899
Synonym:
Target: Adrenergic Receptor
Benzenesulfonamide
T6781
Synonym: Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide
Target: Carbonic Anhydrase
Chroman 1
T14960
Synonym:
Target: ROCK
Dichlorphenamide
T6469
Synonym: Diclofenamide,Daranide,Antidrasi
Target: Carbonic Anhydrase
Brinzolamide
T0142
Synonym: AL-4862
Target: Carbonic Anhydrase
Methazolamide
T0106
Synonym: L584601,CL 8490
Target: Carbonic Anhydrase
Benzolamide
T23782
Synonym: CL-11366,W 1803,CL 11366,CL11366,W-1803
Target: Carbonic Anhydrase
Promethazine
T0445
Synonym: Proazamine,Diphergan
Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
TG-46
T20743
Synonym: TG46,TG 46
Target: FLT, JAK
Demecarium bromide
T7213
Synonym: BC-48
Target: AChE
Betaxolol
T6408
Synonym: Kerlone,SL 75212,Betoptic
Target: Adrenergic Receptor
Rentiapril racemate
T16731
Synonym: (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril
Target: Angiotensin-converting Enzyme (ACE)
MRE3008F20
T16132
Synonym:
Target: cAMP, Adenosine Receptor
Brimonidine Tartrate
T6422
Synonym: AGN190342 tartrate,304 tartrate,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate
Target: Adrenergic Receptor
Bupranolol
T8580
Synonym:
Target: Adrenergic Receptor
Dipivefrin hydrochloride
T0103
Synonym: Dipivefrin HCL
Target: Adrenergic Receptor, AChR
Trabodenoson
T34914
Synonym: INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875
Target: Adenosine Receptor
Bimatoprost
T2538
Synonym: AGN 192024
Target: Prostaglandin Receptor
Binospirone
T71138L
Synonym: MDL 73005EF
Target: 5-HT Receptor
Levobetaxolol hydrochloride
T6565
Synonym: Betaxon,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl
Target: Adrenergic Receptor
Travoprost
T5841
Synonym: Flu-Ipr,Fluprostenol isopropyl ester,AL6221
Target: Prostaglandin Receptor
Brimonidine
T20157
Synonym: AGN190342,Bromoxidine,AGN 190342,AGN-190342
Target: Adrenergic Receptor
TLC2976-0103
T9847
Synonym:
Target:
Evodenoson
T31731
Synonym: DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313
Target: Adenosine Receptor
Aceclidine
T19870
Synonym: 3-Acetoxyquinuclidine,1-azabicyclo[2.2.2]octan-3-yl acetate,NSC657843,3-quinuclidinyl acetate,NSC-657843,Glaucostat,NSC 657843,Quinuclidin-3-yl acetate
Target: AChR
Acetazolamide sodium
T60351
Synonym: OT-302 sodium
Target: Carbonic Anhydrase
Sonepcizumab
T76828
Synonym: LT 1009
Target: LPL Receptor
Taprenepag
T3174
Synonym: CP-544326
Target: Prostaglandin Receptor
Apraclonidine hydrochloride
T21371
Synonym: Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum
Target: Adrenergic Receptor
Latanoprostene bunod
T15719
Synonym: LBN,NCX116
Target: Others
2-Chlorophenylboronic acid
T77513
Synonym:
Target: FAAH
Echothiophate Iodide
T31600
Synonym: Phospholine iodide,Ecostigmini Sodidum,Iodide, Echothiophate,Echodide,Ecothiophate iodide
Target:
Dipivefrin
T0103L
Synonym: K 30081,K-30081,Dipivefrinum,Dipivefrina,K30081
Target:
Levobunolol
T32699
Synonym: Levobunololum,Liquifilm,AK-Beta,Betegan
Target:
GW-876167
T27518
Synonym: PRX-00933,PNU-183933,GW876167,BVT933,BVT-933
Target:
NCX-274
T71250
Synonym:
Target:
NCX-278
T71249
Synonym:
Target:
Proxodolol hydrochloride
T28457
Synonym:
Target:
Unoprostone isopropyl
T20644
Synonym: UF021,Rescula,UF-021,UF 021
Target:
Aganepag isopropyl
T29708
Synonym: AGN-210961,AGN 210961,AGN210961
Target:
AL-16049
T29811
Synonym: AL 16049,AL16049
Target:
Iganidipine HCl
T71333
Synonym:
Target:
Simenepag isopropyl
T34644
Synonym: AGN210669,AGN-210669,AGN 210669
Target:
Dorzolamide
T22743
Synonym:
Target: Others
Propionylcarnitine
T19528
Synonym: Propionyl carnitine
Target: Others
KR-31378
T27739
Synonym: MSH1001,DNB 001,DNB-001,DNB001,MSH-1001,KR31378
Target:
CP-432
T31054
Synonym: CP432,CP734432,CP 734432,CP-734432
Target:
Unoprostone
T13955
Synonym:
Target: Others
Pirnabine
T75031
Synonym:
Target:
Naboctate
T68756
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TN1540 Cyanidin-3,5-O-diglucoside chloride Others
Cyanidin-3,5-O-diglucoside chloride has antioxidant activity. Cyanidin-3,5-O-diglucoside inhibits hyperbaric pressure-induced GLAST decrease and can be used in glaucoma studies. Cyanidin-3,5-O-diglucoside chloride is eas...
T1287 Synephrine Oxedrine Endogenous Metabolite , Adrenergic Receptor
Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
T1231 Pilocarpine nitrate Pilagan,Pilofrin AChR
Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
TN1465 Cannabigerol NOS , 5-HT Receptor , ROS
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur...
T39168 Epsilon-(gamma-glutamyl)-lysine Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicat...
T20636 Latrunculin B LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644 Antifungal
Latrunculin B, an alkaloid from the Red Sea sponge, is an actin polymerization inhibitor with antifungal and antiprotozoal activity.Latrunculin B modulates the electrophysiological characteristics of the pulmonary veins ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-02248 Myocilin Protein, Human, Recombinant (His) Human HEK293
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid o...
TMPY-00366 ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04245 ANGPT1/Angiopoietin-1 Protein, Mouse, Recombinant (His) Mouse HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPK-00731 ANGPTL7 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled ...
TMPY-05351 ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPK-00730 ANGPTL7 Protein, Human, Recombinant (His & Avi) Human HEK293
Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled ...
TMPY-03501 Optineurin Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking ...
TMPJ-00680 ANGPTL7 Protein, Human, Recombinant (His) Human Human Cells
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain....