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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8899 | Metipranolol | Adrenergic Receptor | |
Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc... | |||
T6781 | Benzenesulfonamide | Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide | Carbonic Anhydrase |
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases. | |||
T14960 | Chroman 1 | ROCK | |
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM). | |||
T6469 | Dichlorphenamide | Diclofenamide,Daranide,Antidrasi | Carbonic Anhydrase |
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma. | |||
T0142 | Brinzolamide | AL-4862 | Carbonic Anhydrase |
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. | |||
T0106 | Methazolamide | L584601,CL 8490 | Carbonic Anhydrase |
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. | |||
T23782 | Benzolamide | CL-11366,W 1803,CL 11366,CL11366,W-1803 | Carbonic Anhydrase |
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons. | |||
T0445 | Promethazine | Proazamine,Diphergan | CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor |
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) . | |||
T20743 | TG-46 | TG46,TG 46 | FLT , JAK |
TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma. | |||
T7213 | Demecarium bromide | BC-48 | AChE |
Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent. | |||
T6408 | Betaxolol | Kerlone,SL 75212,Betoptic | Adrenergic Receptor |
Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma. | |||
T16731 | Rentiapril racemate | (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril | Angiotensin-converting Enzyme (ACE) |
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research. | |||
T16132 | MRE3008F20 | cAMP , Adenosine Receptor | |
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9 | |||
T6422 | Brimonidine Tartrate | AGN190342 tartrate,304 tartrate,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate | Adrenergic Receptor |
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hyperten... | |||
T8580 | Bupranolol | Adrenergic Receptor | |
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. | |||
T0103 | Dipivefrin hydrochloride | Dipivefrin HCL | Adrenergic Receptor , AChR |
Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma. | |||
T34914 | Trabodenoson | INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875 | Adenosine Receptor |
Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma. | |||
T2538 | Bimatoprost | AGN 192024 | Prostaglandin Receptor |
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension. | |||
T71138L | Binospirone | MDL 73005EF | 5-HT Receptor |
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction. | |||
T6565 | Levobetaxolol hydrochloride | Betaxon,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl | Adrenergic Receptor |
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma. | |||
T5841 | Travoprost | Flu-Ipr,Fluprostenol isopropyl ester,AL6221 | Prostaglandin Receptor |
Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist. | |||
T20157 | Brimonidine | AGN190342,Bromoxidine,AGN 190342,AGN-190342 | Adrenergic Receptor |
Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P. It is used to treat open-angle glaucoma or ocular hypertension | |||
T9847 | TLC2976-0103 | ||
ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction [1]. | |||
T31731 | Evodenoson | DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313 | Adenosine Receptor |
Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumo... | |||
T19870 | Aceclidine | 3-Acetoxyquinuclidine,1-azabicyclo[2.2.2]octan-3-yl acetate,NSC657843,3-quinuclidinyl acetate,NSC-657843,Glaucostat,NSC 657843,Quinuclidin-3-yl acetate | AChR |
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure. | |||
T60351 | Acetazolamide sodium | OT-302 sodium | Carbonic Anhydrase |
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and alt... | |||
T76828 | Sonepcizumab | LT 1009 | LPL Receptor |
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi... | |||
T3174 | Taprenepag | CP-544326 | Prostaglandin Receptor |
Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. | |||
T21371 | Apraclonidine hydrochloride | Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum | Adrenergic Receptor |
Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco... | |||
T15719 | Latanoprostene bunod | LBN,NCX116 | Others |
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o... | |||
T77513 | 2-Chlorophenylboronic acid | FAAH | |
2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new drugs.2-Chlorophenylboronic acid has an inhibitory effect o... | |||
T31600 | Echothiophate Iodide | Phospholine iodide,Ecostigmini Sodidum,Iodide, Echothiophate,Echodide,Ecothiophate iodide | |
Echothiophate iodide is an effective long-acting cholinesterase inhibitor for the treatment of glaucoma. | |||
T0103L | Dipivefrin | K 30081,K-30081,Dipivefrinum,Dipivefrina,K30081 | |
Dipivefrin is a prodrug of epinephrine, and is used to treat open-angle glaucoma. | |||
T32699 | Levobunolol | Levobunololum,Liquifilm,AK-Beta,Betegan | |
Levobunolol is a nonselective beta-blocker. It is used topically to treat glaucoma. | |||
T27518 | GW-876167 | PRX-00933,PNU-183933,GW876167,BVT933,BVT-933 | |
GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma. | |||
T71250 | NCX-274 | ||
NCX-274 is a ROCK inhibitor and NO-donating anti-glaucoma agent | |||
T71249 | NCX-278 | ||
NCX-278 is a ROCK inhibitor and NO-donating anti-glaucoma agent. | |||
T28457 | Proxodolol hydrochloride | ||
Proxodolol, a β-adrenergic receptor antagonist, is used potentially for the treatment of glaucoma, hypertension and angina. | |||
T20644 | Unoprostone isopropyl | UF021,Rescula,UF-021,UF 021 | |
Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma. | |||
T29708 | Aganepag isopropyl | AGN-210961,AGN 210961,AGN210961 | |
Aganepag isopropyl can be used to treat Glaucoma. | |||
T29811 | AL-16049 | AL 16049,AL16049 | |
AL-16049 is an FP-Class prostaglandin analog which may be useful in the treatment of glaucoma and ocular hypertension. | |||
T71333 | Iganidipine HCl | ||
NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for the treatment of glaucoma. | |||
T34644 | Simenepag isopropyl | AGN210669,AGN-210669,AGN 210669 | |
Simenepag isopropyl can be used for the treatment of Glaucoma, Ocular Hypertension. | |||
T22743 | Dorzolamide | Others | |
Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor. | |||
T19528 | Propionylcarnitine | Propionyl carnitine | Others |
Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu | |||
T27739 | KR-31378 | MSH1001,DNB 001,DNB-001,DNB001,MSH-1001,KR31378 | |
KR-31378, a K(ATP) channel activator, is used potentially for the treatment of ocular hypertension and glaucoma. | |||
T31054 | CP-432 | CP432,CP734432,CP 734432,CP-734432 | |
CP-432 (CP-734432) is an EP4 prostaglandin agonist for the treatment of glaucoma and ocular hypertension. | |||
T13955 | Unoprostone | Others | |
Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension. | |||
T75031 | Pirnabine | ||
Pirnabine, a cannabinoid receptor ligand, is utilized in glaucoma research [1]. | |||
T68756 | Naboctate | ||
Naboctate is a synthetic cannabinoid receptor agonist. It has antiemetic, sedative, anxiolytic and anti-glaucoma properties. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1540 | Cyanidin-3,5-O-diglucoside chloride | Others | |
Cyanidin-3,5-O-diglucoside chloride has antioxidant activity. Cyanidin-3,5-O-diglucoside inhibits hyperbaric pressure-induced GLAST decrease and can be used in glaucoma studies. Cyanidin-3,5-O-diglucoside chloride is eas... | |||
T1287 | Synephrine | Oxedrine | Endogenous Metabolite , Adrenergic Receptor |
Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma. | |||
T1231 | Pilocarpine nitrate | Pilagan,Pilofrin | AChR |
Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. | |||
TN1465 | Cannabigerol | NOS , 5-HT Receptor , ROS | |
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur... | |||
T39168 | Epsilon-(gamma-glutamyl)-lysine | Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH | |
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicat... | |||
T20636 | Latrunculin B | LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644 | Antifungal |
Latrunculin B, an alkaloid from the Red Sea sponge, is an actin polymerization inhibitor with antifungal and antiprotozoal activity.Latrunculin B modulates the electrophysiological characteristics of the pulmonary veins ... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-05435 | ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-02248 | Myocilin Protein, Human, Recombinant (His) | Human | HEK293 |
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid o... | |||
TMPY-00366 | ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-04245 | ANGPT1/Angiopoietin-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPK-00731 | ANGPTL7 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled ... | |||
TMPY-05351 | ANGPT1/Angiopoietin-1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPK-00730 | ANGPTL7 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled ... | |||
TMPY-03501 | Optineurin Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking ... | |||
TMPJ-00680 | ANGPTL7 Protein, Human, Recombinant (His) | Human | Human Cells |
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain.... |