|
T5639 |
Lufenuron
|
Fluphenacur |
Parasite
|
|
Lufenuron (Fluphenacur) is a chitin-synthesis inhibitor. |
|
T15102 |
Dexamethasone palmitate
|
DXP |
Glucocorticoid Receptor
|
|
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... |
|
T19438 |
Myristyl nicotinate
|
Tetradecyl nicotinate |
GPR
|
|
Myristyl nicotinate (Tetradecyl nicotinate) is an ester prodrug being developed for delivery of nicotinic acid (NIC) into the skin for prevention of actinic keratosis and its progression to skin cancer. |
|
T1065 |
Baclofen
|
Lioresal |
GABA Receptor
|
|
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... |
|
T21404 |
Fluticasone furoate
|
Veramyst,Allermist,Avamys,Fluticasone furoate |
Glucocorticoid Receptor
|
|
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... |
|
T8630 |
Baclofen hydrochloride
|
4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride |
GABA Receptor
|
|
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe... |
|
T1418 |
Bucladesine sodium
|
dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt |
PKA
,
PDE
|
|
Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in... |
|
T73506 |
TH-Z93
|
THZ93 |
Antibacterial
|
|
TH-Z93 is a potent FPPS inhibitor (IC50:90 nM) and a lipophilic bisphosphonate. |
|
T15118 |
DiD perchlorate
|
|
Others
|
|
DiD perchlorate is a lipophilic cyanine dye. |
|
T60151 |
CP-447697
|
|
Complement System
|
|
CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research. |
|
T17109 |
TMRM Perchlorate
|
T668 |
Others
|
|
TMRM Perchlorate (T668) is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm). |
|
T67812 |
Tenifatecan
|
SN2310 |
|
|
Tenifatecan (SN2310) is a highly lipophilic preparation of 7-ethyl-10-hydroxycamptothecin (SN) with potential antitumor activity. |
|
T0876 |
Clioquinol
|
Chinoform,Iodochlorhydroxyquin |
Mitophagy
,
Antibiotic
,
Autophagy
,
Antifungal
|
|
Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. |
|
T40418 |
DiO
|
DiOC18(3),3,3'-Dioctadecyloxacarbocyanine perchlorate |
Others
|
|
DiO (DiOC18(3)) is a fluorescent lipophilic tracer and can be widely used to label cells, organelles, liposomes, viruses, and lipoproteins. |
|
T2405 |
Revaprazan hydrochloride
|
YH1885 |
ATPase
,
COX
,
Antibacterial
|
|
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. |
|
T40857 |
Calcium ionophore II
|
Calcium ionophore II,N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide |
Others
|
|
Calcium ionophore II (N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide) is a lipophilic ionophore that can be used in preparing calcium ion-selective electrode. |
|
TQ0095 |
Brincidofovir
|
CMX001,HDP-CDV |
Others
,
Antiviral
,
HSV
|
|
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses. |
|
T78393 |
C12FDG
|
5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside |
|
|
C12FDG (5-Dodecanoylaminofluorescein di-beta-D-Galactopyranoside) is used as a lipophilic green fluorescent substrate for detecting beta-galactose activity, a green fluorescent substrate, is a senescence marker and is of... |
|
T1439 |
Lacidipine
|
SN-305,GX-1048,GR-43659X |
Apoptosis
,
Calcium Channel
,
Reactive Oxygen Species
|
|
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... |
|
T2569 |
Chlorotrianisene
|
tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
,
COX
|
|
Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but... |
|
T11717 |
JHU395
|
|
Apoptosis
|
|
|
|
T15378L |
Gemcitabine elaidate hydrochloride
|
CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride |
Others
|
|
Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. In contrast to gemcitabine, G... |
|
T36957 |
BODIPY 493/503
|
BDP 493/503 lipid stain,Pyrromethene 546 |
Others
|
|
BODIPY 493/503 (Pyrromethene 546) is a lipophilic fluorescent probe with Ex/Em of 493/503 nm. BODIPY 493/503 localizes to polar lipids and can be used to label cellular neutral lipid contents and for live and fixed cell ... |
|
T15129 |
DiI
|
DiIC18(3) |
Others
|
|
DiI (DiIC18(3)) is a lipophilic membrane dye. It diffuses laterally to stain the entire cell. DiI is excited to emit orange-red fluorescence which is weak in water but strong and photostable when incorporated into membra... |
|
T16858 |
SBE-β-CD
|
Sulfobutylether-β-Cyclodextrin |
Others
|
|
SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-β-CD is widely used as a c... |
|
T36958 |
BODIPY 505/515
|
|
|
|
BODIPY 505/515 is a lipophilic fluorescent probe that localises to intracellular liposomes and has been used to label lipid droplets.BODIPY 505/515 has been used in electron microscopy, epifluorescence microscopy, confoc... |
|
T2627 |
Nolatrexed dihydrochloride
|
Thymitaq,AG 337 |
DNA/RNA Synthesis
|
|
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidyla... |
|
T6170 |
Elesclomol
|
STA-4783 |
Apoptosis
,
HSP
,
Reactive Oxygen Species
|
|
Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-medi... |
|
T21297 |
Miriplatin hydrate
|
SM-11355 (hydrate),Miripla,Miriplatin,SM 11355,SM11355,SM-11355,Miriplatin hydrate |
DNA Alkylation
|
|
Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin hydrate is a lipophilic platinum complex that can ... |
|
T15609 |
JC-1
|
CBIC2 |
Others
|
|
JC-1 (CBIC2) is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential. JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry. |
|
T25360 |
Eclazolast
|
RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871 |
Others
|
|
Eclazolast (RHC 2871) is a lipophilic anti-allergic compound that inhibits mediator release in a mast cell model.Eclazolast inhibits extracellular secretion by affecting only the direct processes associated with Fc(epsil... |
|
T27624 |
Iptakalim Hydrochloride
|
|
Potassium Channel
,
AChR
|
|
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2... |
|
T60774 |
NITD-916
|
NITD916,NITD 916 |
Antibiotic
|
|
NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NA... |
|
T6334 |
Ridaforolimus
|
AP23573,Deforolimus,MK-8669 |
mTOR
,
Autophagy
|
|
Ridaforolimus (AP23573) is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamyc... |
|
T6929 |
Pantoprazole sodium
|
Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc |
Apoptosis
,
Others
,
Proton pump
,
HIF
,
Autophagy
|
|
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters... |
|
T24473 |
Mixanpril
|
|
|
|
Mixanpril is an RB 105 lipophilic prodrug. |
|
T24300 |
L 645151
|
L645151,L-645151 |
|
|
L 645151 is an inhibitor of lipophilic CA. |
|
T28326 |
PD 130883
|
PD-130883,PD130883 |
|
|
PD 130883 is a potent lipophilic quinazoline antifolate. |
|
T13117 |
Teludipine hydrochloride
|
GR53992B,GX1296B |
Calcium Channel
|
|
Teludipine hydrochloride is a blocker of lipophilic calcium channel. |
|
T31381 |
Deoxylimonol
|
Deoxy-alpha-limonol |
|
|
Deoxylimonol is a lipophilic compound found in human feces. |
|
T23672 |
AH-1058 HCl
|
AH 1058 HCl |
|
|
AH-1058 HCl is a lipophilic antiarrhythmic calcium channel blocker. |
|
T32257 |
Janolusimide
|
|
|
|
Janolusimide is a kind of lipophilic tripeptide marine toxin. |
|
T27153 |
Dexamethasone cipecilate
|
NS126,NS-126,NS 126 |
|
|
Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid. |
|
T26799 |
Bibn 99
|
Bibn99,Bibn-99 |
|
|
Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease. |
|
T30841 |
Cgp 57813
|
Cgp-57813,Cgp57813 |
|
|
CGP 57813 is a lipophilic compound, which can be used as an inhibitor of HIV-1 protease. |
|
TD0083 |
DiIiodide1,1‘-Dioctadecyl-3,3,3’,3‘-tetramethylindocarbocyanine iodide]
|
|
|
|
DiI iodide1 is one of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures. The fluorescence of these environment-sensitive dyes is greatly enhanced when incorporated into membranes or bo... |
|
T15004 |
CP-532623
|
|
CETP
|
|
CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol. |
|
TD0084 |
DiI triflate [1,1‘-Dioctadecyl-3,3,3’,3‘-tetramethylindocarbocyanine triflate]
|
|
|
|
DiI triflate is one of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures. The fluorescence of these environment-sensitive dyes is greatly enhanced when incorporated into membranes or b... |
|
T68515 |
AZD-1175
|
|
|
|
AZD-1175 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes and obesity. |
|
T68500 |
AZD-2207
|
|
|
|
AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes mellitus and obesity. |
