29
5
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7061 | Duloxetine | Serotonin Transporter | |
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder. | |||
T1409 | Methocarbamol | Lumirelax,Metocarbamol,AHR 85,Robaxin | Sodium Channel , Carbonic Anhydrase |
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc... | |||
T1471 | Duloxetine hydrochloride | Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i... | |||
T27209 | Droxicam | Droxicamum | Others |
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders. | |||
T34385 | Ronacaleret HCl | SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 | CaSR |
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders. | |||
T1610 | Metaxalone | Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438 | Others |
Metaxalone (Methaxalonum) (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. | |||
T28453L | Propiram fumarate HCl | Propiram fumarate HCl(15686-91-6 Free base) | Opioid Receptor |
Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain. | |||
T24755 | Salnacedin | G-201,SCY,G-201,G201,SCY,G 201 | Others |
Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis. | |||
T33876L1 | Panomifene TFA | Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA | Estrogen/progestogen Receptor |
Panomifene TFA(GYKl13504 TFA) is a small molecule antagonist of ERs with anticancer activity that can be used to study breast cancer and musculoskeletal diseases. | |||
T15358 | Funapide | TV 45070,XEN402 | Sodium Channel |
Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves. | |||
T29663 | ADL-5747 | ADL-5747 (free base),ADL5747,ADL-5747 free base | Opioid Receptor |
ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletal disorders, and may be used in the study of postherpetic neuralgia, ... | |||
T0858 | Flufenamic acid | Arlef,Nichisedan,Achless | Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite |
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. | |||
T72023 | JB002 | Myosin | |
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. | |||
T68126 | Pemedolac | Dexpemedolac | COX |
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders. | |||
T7725 | Albaconazole | W 0027,UR-9825,UR9825,W-0027 | P450 , Antifungal |
Albaconazole (W-0027) is a small molecule fungal cytochrome P450 family member 51 (fungal CYP51A1) inhibitor. It is used in the treatment of fungal infections, skin and musculoskeletal disorders, and can be used in the s... | |||
T0855 | (R)-Naproxen | COX | |
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis... | |||
T68108L | Moxilubant HCl | Moxilubant hcl(146978-48-5 Free base) | LTR |
Moxilubant HCl is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders, and may be used in studies of psoriasis and rheumatoid art... | |||
T41303 | Isoflupredone | Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone | Others |
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio... | |||
T67385 | Neratinib maleate | HKI-272 maleate | EGFR , HER |
Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ... | |||
T67952 | JB062 | Myosin | |
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se... | |||
T27633 | Isonixin | Nixyn,Isonixine | |
Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders. | |||
T34863 | Thurfyl Salicylate | Tetrahydrofurfuryl salicylate | |
Thurfyl Salicylate (tetrahydrofurfuryl Salicylate) is a redness preparation used for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain. | |||
T0183L | Pramiracetam Sulfate | CNS-1879,CI879,CI-879,CI 879,Pramiracetam | |
Thurfyl salicylate is a reddening agent for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain. | |||
T27573 | Ibuproxam | Ibuproxamum,G-277 | |
Ibuproxam, a nonsteroidal antiinflammatory drug (NSAID), is used for the treatment of musculoskeletal pain, arthritis, and soft-tissue disorders. | |||
T68563 | Piroxicam olamine | ||
Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmeno... | |||
T68211 | Piroxicam betadex | ||
Piroxicam betadex is a nonsteroidal anti-inflammatory drug. The mechanism of action of piroxicam is as a cyclooxygenase Inhibitor. It is well established in treating rheumatoid arthritis and osteoarthritis and used for ... | |||
T68108 | Moxilubant | LTR | |
Moxilubant is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders, and may be used in studies of psoriasis and rheumatoid arthrit... | |||
T28685 | SB236057 | SB-236057,SB 236057 | |
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote... | |||
TP1853 | TP508 | ||
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibrobla... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-04126 | MUSTN1 Protein, Human, Recombinant (His) | Human | E. coli |
MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ... | |||
TMPJ-00227 | Follistatin 288 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid . Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein w... | |||
TMPY-02963 | Calcineurin A/PPP3CA Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily. It is the alpha catalytic subunit of protein phosphatase 2B (PP2B). PP2B is a holoenzyme that is comprised of a ca... | |||
TMPY-02220 | HRAS Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It... | |||
TMPY-03397 | TPPP3 Protein, Human, Recombinant (His) | Human | E. coli |
TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons... |