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Search Results for " musculoskeletal "

ターゲット

29

阻害剤

5

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T1409 Methocarbamol Lumirelax,Metocarbamol,AHR 85,Robaxin Sodium Channel , Carbonic Anhydrase
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc...
T1471 Duloxetine hydrochloride Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T27209 Droxicam Droxicamum Others
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders.
T34385 Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 CaSR
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
T1610 Metaxalone Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438 Others
Metaxalone (Methaxalonum) (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.
T28453L Propiram fumarate HCl Propiram fumarate HCl(15686-91-6 Free base) Opioid Receptor
Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.
T24755 Salnacedin G-201,SCY,G-201,G201,SCY,G 201 Others
Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis.
T33876L1 Panomifene TFA Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA Estrogen/progestogen Receptor
Panomifene TFA(GYKl13504 TFA) is a small molecule antagonist of ERs with anticancer activity that can be used to study breast cancer and musculoskeletal diseases.
T15358 Funapide TV 45070,XEN402 Sodium Channel
Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves.
T29663 ADL-5747 ADL-5747 (free base),ADL5747,ADL-5747 free base Opioid Receptor
ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletal disorders, and may be used in the study of postherpetic neuralgia, ...
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T72023 JB002 Myosin
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
T68126 Pemedolac Dexpemedolac COX
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.
T7725 Albaconazole W 0027,UR-9825,UR9825,W-0027 P450 , Antifungal
Albaconazole (W-0027) is a small molecule fungal cytochrome P450 family member 51 (fungal CYP51A1) inhibitor. It is used in the treatment of fungal infections, skin and musculoskeletal disorders, and can be used in the s...
T0855 (R)-Naproxen COX
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...
T68108L Moxilubant HCl Moxilubant hcl(146978-48-5 Free base) LTR
Moxilubant HCl is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders, and may be used in studies of psoriasis and rheumatoid art...
T41303 Isoflupredone Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone Others
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio...
T67385 Neratinib maleate HKI-272 maleate EGFR , HER
Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ...
T67952 JB062 Myosin
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se...
T27633 Isonixin Nixyn,Isonixine
Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.
T34863 Thurfyl Salicylate Tetrahydrofurfuryl salicylate
Thurfyl Salicylate (tetrahydrofurfuryl Salicylate) is a redness preparation used for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain.
T0183L Pramiracetam Sulfate CNS-1879,CI879,CI-879,CI 879,Pramiracetam
Thurfyl salicylate is a reddening agent for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain.
T27573 Ibuproxam Ibuproxamum,G-277
Ibuproxam, a nonsteroidal antiinflammatory drug (NSAID), is used for the treatment of musculoskeletal pain, arthritis, and soft-tissue disorders.
T68563 Piroxicam olamine
Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmeno...
T68211 Piroxicam betadex
Piroxicam betadex is a nonsteroidal anti-inflammatory drug. The mechanism of action of piroxicam is as a cyclooxygenase Inhibitor. It is well established in treating rheumatoid arthritis and osteoarthritis and used for ...
T68108 Moxilubant LTR
Moxilubant is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders, and may be used in studies of psoriasis and rheumatoid arthrit...
T28685 SB236057 SB-236057,SB 236057
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote...
TP1853 TP508
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibrobla...

Compounds

Duloxetine
T7061
Synonym:
Target: Serotonin Transporter
Methocarbamol
T1409
Synonym: Lumirelax,Metocarbamol,AHR 85,Robaxin
Target: Sodium Channel, Carbonic Anhydrase
Duloxetine hydrochloride
T1471
Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Droxicam
T27209
Synonym: Droxicamum
Target: Others
Ronacaleret HCl
T34385
Synonym: SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689
Target: CaSR
Metaxalone
T1610
Synonym: Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438
Target: Others
Propiram fumarate HCl
T28453L
Synonym: Propiram fumarate HCl(15686-91-6 Free base)
Target: Opioid Receptor
Salnacedin
T24755
Synonym: G-201,SCY,G-201,G201,SCY,G 201
Target: Others
Panomifene TFA
T33876L1
Synonym: Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA
Target: Estrogen/progestogen Receptor
Funapide
T15358
Synonym: TV 45070,XEN402
Target: Sodium Channel
ADL-5747
T29663
Synonym: ADL-5747 (free base),ADL5747,ADL-5747 free base
Target: Opioid Receptor
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
JB002
T72023
Synonym:
Target: Myosin
Pemedolac
T68126
Synonym: Dexpemedolac
Target: COX
Albaconazole
T7725
Synonym: W 0027,UR-9825,UR9825,W-0027
Target: P450, Antifungal
(R)-Naproxen
T0855
Synonym:
Target: COX
Moxilubant HCl
T68108L
Synonym: Moxilubant hcl(146978-48-5 Free base)
Target: LTR
Isoflupredone
T41303
Synonym: Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone
Target: Others
Neratinib maleate
T67385
Synonym: HKI-272 maleate
Target: EGFR, HER
JB062
T67952
Synonym:
Target: Myosin
Isonixin
T27633
Synonym: Nixyn,Isonixine
Target:
Thurfyl Salicylate
T34863
Synonym: Tetrahydrofurfuryl salicylate
Target:
Pramiracetam Sulfate
T0183L
Synonym: CNS-1879,CI879,CI-879,CI 879,Pramiracetam
Target:
Ibuproxam
T27573
Synonym: Ibuproxamum,G-277
Target:
Piroxicam olamine
T68563
Synonym:
Target:
Piroxicam betadex
T68211
Synonym:
Target:
Moxilubant
T68108
Synonym:
Target: LTR
SB236057
T28685
Synonym: SB-236057,SB 236057
Target:
TP508
TP1853
Synonym:
Target:

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04126 MUSTN1 Protein, Human, Recombinant (His) Human E. coli
MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ...
TMPJ-00227 Follistatin 288 Protein, Human, Recombinant (His) Human HEK293 Cells
Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid . Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein w...
TMPY-02963 Calcineurin A/PPP3CA Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily. It is the alpha catalytic subunit of protein phosphatase 2B (PP2B). PP2B is a holoenzyme that is comprised of a ca...
TMPY-02220 HRAS Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It...
TMPY-03397 TPPP3 Protein, Human, Recombinant (His) Human E. coli
TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons...