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Search Results for " periodontal "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T6593	ML324		Histone Demethylase , Others , HSV
	ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).		Histone Demethylase , Others , HSV
T15779	LP-533401 hydrochloride		5-HT Receptor
	LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.		5-HT Receptor
T0291	Flurbiprofen	dl-Flurbiprofen	Apoptosis , COX , MRP
	Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.		Apoptosis , COX , MRP
T67915	Succinate/succinate receptor antagonist 1		Others
	Succinate/succinate receptor antagonist 1 is a potent succinate receptor antagonist. Succinate/succinate receptor antagonist 1 interrupts succinate signals in gingival tissue and inhibits the activation of SucnRl Antagon...		Others
T69082	Flurbiprofen sodium
	Flurbiprofen sodium is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase.
T40274	XVA143	XVA143
	XVA143, an α/β I-like allosteric antagonist, effectively blocks LFA-1 dependent firm adhesion but simultaneously increases adhesion under shear flow and rolling conditions, both in vitro and in vivo.
T64692	AMY-101 acetate
	Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe...

Compounds

ML324

T6593

Synonym:

Target: Histone Demethylase, Others, HSV

LP-533401 hydrochloride

T15779

Synonym:

Target: 5-HT Receptor

Flurbiprofen

T0291

Synonym: dl-Flurbiprofen

Target: Apoptosis, COX, MRP

Succinate/succinate receptor antagonist 1

カタログ番号	製品名	別名	ターゲット
T79993	Oleanolic aldehyde
	Oleanolic aldehyde, an antimicrobial agent, effectively hinders the growth of oral pathogens Streptococcus mutans and Porphyromonas gingivalis, implicated in dental caries and periodontal disease. The compound exhibits m...
TN3144	6,4'-Dihydroxy-7-methoxyflavanone	檀木	ERK , IL Receptor , Antioxidant , TNF , NF-κB , MAPK , Prostaglandin Receptor , JNK , Autophagy

天然物製品

6,4'-Dihydroxy-7-methoxyflavanone

TN3144

Synonym: 檀木

Target: ERK, IL Receptor, Antioxidant, TNF, NF-κB, MAPK, Prostaglandin Receptor, JNK, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00962	Asporin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Asporin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9BXN1.
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPH-03151	Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	P. pastoris (Yeast)
	Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defen...
TMPK-01370	GRP-10 proform Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties, and neuropeptides have previously been suggested to play a role in the complex cascade of chemical activity associated...
TMPH-03153	Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defen...
TMPH-01076	CEMP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum. Bind...
TMPH-03152	Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His)	Porphyromonas gingivalis	E. coli
	Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defen...
TMPH-03158	PAD Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the p...
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...