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Search Results for " probe "

477

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14

天然化合物

8

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T31008 Copper probe CF4 Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob
Copper probe CF4 (Copper fluor CF4) is a fluorescent copper probe that can be used to study colon cancer.
T8483 Cysteine thiol probe Methyl (4-bromobenzoyl)-L-cysteinate Others
Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites
T38855 Melanin probe-1
Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution pr...
T40235 Kbz probe 1
Kbz probe 1, an adaptable probe utilized for examining histone benzoylation and interactions within living cells, showcases extensive versatility.
T36104 Citrulline-specific Probe-Rhodamine
Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has...
T18926 Biotin-probe 1 Others
Biotin-probe 1 is a non-radiolabeled probe and can be applied to in situ hybridization.
T35575 Aldehyde Reactive Probe (trifluoroacetate salt)
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated...
T37720 Difluorinated H2S Fluorescent Probe 1
Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glut...
T19064 TAMRA-probe 1 Others
TAMRA-probe 1 is a fluorescent probe for labeling.
T18915 Alkyne-probe 1 Others
Alkyne-probe 1 is usually used as an Alkyne-labeled fluorescent or chemical probe.
T12562 Protein kinase affinity probe 1 Others
Protein kinase affinity probe 1 is a protein kinase affinity probe for the functional identification of protein kinases (PKs).
T32104 Hras-1Y i-motif Probe-1
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it.
T64306 CXCR4 probe 1
CXCR4 probe 1 (compound 5) is a potent and specific CXCR4-targeted PET tracer that acts on the CXCR4-specific antagonist TN14003 (IC50: 6.9 nM). The CXCR4 probe 1 has potential as a CXCR4-specific imaging probe for the d...
T74212 BLT2 probe 1 Leukotriene Receptor
BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmacology across various assay systems [1]. As BLT2 is a valuab...
T75346 PARP7-probe-1
PARP7-probe-1, a chemiluminescent-labeled and biotinylated probe, selectively binds to the PARP7 active site, facilitating research into PARP7 function [1].
T74459 Y1R probe-1
Compound 39, also known as Y1R probe-1, is a high-affinity fluorescent probe targeting the Neuropeptide Y Y1 Receptor, with potential applications in cancer research [1].
T64640 Melanin probe-2
Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-pi...
T74604 CB2R probe 1
CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of 130 nM. Notably, it demonstrates low cytotoxicity within can...
T72328 Cyclopropenone probe 1
Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1) , by covalently binding at the catalytic active site.
T80522 Keap1-Nrf2 probe
Keap1-Nrf2 probe [1] is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor erythroid 2-related factor 2 (Nrf2).
T83764 Sulfane Sulfur Probe 4 ​SSP4
Sulfane Sulfur Probe 4 (SSP4) serves as a fluorescent probe targeting sulfane sulfur species, encompassing hydrogen sulfide-derived polysulfides, hydropersulfides, and persulfides generated endogenously. Upon interacting...
T32416 KP-1 KP 1,KP1,Kyoto Probe 1
KP-1 is a selective fluorescent probe for labeling human pluripotent stem cells.
T38117 WSP-5 Washington State Probe-5,WSP-5
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a reactive disulfide-...
T15082 DDAO Others
DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en...
T30874 Chemodosimeter 1 Pi-Probe-1,Chemodosimeter-1
Chemodosimeter 1 is designed as a highly selective phosphate ion (PI) sensor capable of demonstrating exogenous and endogenous ATP-catalysed PI production and is the first probe capable of tracking PI production and enri...
T19036 Ninhydrin Others
Ninhydrin is a chromogenic analytical probe for the quantification of proteins and amino acids.
T74613 G-quadruplex DNA fluorescence probe 1
Compound E1, also known as G-quadruplex DNA fluorescence probe 1, is a selective fluorescent probe targeting G-quadruplex DNA. It possesses the ability to penetrate membranes and enter living cells, demonstrating low cyt...
T32124 HyP-1 HyP 1,HyP1,Hypoxia Probe 1
HyP-1 is a probe for photoacoustic imaging of hypoxia.
T7900 BAY-474 c-Met/HGFR
BAY-474 is an inhibitor of tyrosine-protein kinase c-Met. It acts as an epigenetics probe
T18968 Dansylcadaverine Monodansyl cadaverine Others , Autophagy
Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.
T0734 Antipyrine Phenazone,Phenazon COX
Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.
T8371 ML188 Virus Protease , SARS-CoV
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
T0778 Phenacetin Acetophenetidin COX
Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market.
T3594 ML346 HSP
ML346 is a novel activator of Hsp70.
T2379 UNC1215 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold higher versus other members of the human MBT family.
T15784 LP99 Epigenetic Reader Domain
LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9).
T8954 ML179 ML-179 Others
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM.
T8551 Nitrobenzylthioinosine NBMPR AChR , Adenosine Receptor
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
T41302 Itaconate-alkyne ITalk Others
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its dire...
T6859 I-BRD9 GSK602 Epigenetic Reader Domain
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.
T14591 Biotin-PEG3-azide Others , PROTAC Linker
Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in PROTAC synthesis.
T5045 GSK4112 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452 Autophagy
GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.
TD0103 Safranin Safranine T,Basic Red 2 Others
Safranin (Basic Red 2) is an industrial dyes.
T5053 Eprobemide LIS 630 MAO , Monoamine Oxidase
Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
T31737 Exiproben sodium salt DCH 21,DCH-21,DCH21
Exiproben sodium salt is a biochemical.
T31736 Exiproben DCH 21
Exiproben is a biochemical.
T25539 Iprobenfos Ricid P,Kitazin P,Kitazin L,Ricid II
Iprobenfos (IBP) is used as an organophosphorus pesticide.
T25987 Probestin
Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.
T18977 Dihydrorhodamine 123 DHR 123 Others
Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λex=488 nm, λem=525 nm).
T33602 NBD-Pen NBDPen,LipiRADICAL Green,NBD Pen,FDV-0042,Funakoshi
NBD-Pen (LipiRADICAL Green) is a fluorescent probe that detects lipid free radicals in living cells.

Compounds

Copper probe CF4
T31008
Synonym: Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob
Target:
Cysteine thiol probe
T8483
Synonym: Methyl (4-bromobenzoyl)-L-cysteinate
Target: Others
Melanin probe-1
T38855
Synonym:
Target:
Kbz probe 1
T40235
Synonym:
Target:
Citrulline-specific Probe-Rhodamine
T36104
Synonym:
Target:
Biotin-probe 1
T18926
Synonym:
Target: Others
Aldehyde Reactive Probe (trifluoroacetate salt)
T35575
Synonym:
Target:
Difluorinated H2S Fluorescent Probe 1
T37720
Synonym:
Target:
TAMRA-probe 1
T19064
Synonym:
Target: Others
Alkyne-probe 1
T18915
Synonym:
Target: Others
Protein kinase affinity probe 1
T12562
Synonym:
Target: Others
Hras-1Y i-motif Probe-1
T32104
Synonym:
Target:
CXCR4 probe 1
T64306
Synonym:
Target:
BLT2 probe 1
T74212
Synonym:
Target: Leukotriene Receptor
PARP7-probe-1
T75346
Synonym:
Target:
Y1R probe-1
T74459
Synonym:
Target:
Melanin probe-2
T64640
Synonym:
Target:
CB2R probe 1
T74604
Synonym:
Target:
Cyclopropenone probe 1
T72328
Synonym:
Target:
Keap1-Nrf2 probe
T80522
Synonym:
Target:
Sulfane Sulfur Probe 4
T83764
Synonym: ​SSP4
Target:
KP-1
T32416
Synonym: KP 1,KP1,Kyoto Probe 1
Target:
WSP-5
T38117
Synonym: Washington State Probe-5,WSP-5
Target:
DDAO
T15082
Synonym:
Target: Others
Chemodosimeter 1
T30874
Synonym: Pi-Probe-1,Chemodosimeter-1
Target:
Ninhydrin
T19036
Synonym:
Target: Others
G-quadruplex DNA fluorescence probe 1
T74613
Synonym:
Target:
HyP-1
T32124
Synonym: HyP 1,HyP1,Hypoxia Probe 1
Target:
BAY-474
T7900
Synonym:
Target: c-Met/HGFR
Dansylcadaverine
T18968
Synonym: Monodansyl cadaverine
Target: Others, Autophagy
Antipyrine
T0734
Synonym: Phenazone,Phenazon
Target: COX
ML188
T8371
Synonym:
Target: Virus Protease, SARS-CoV
Phenacetin
T0778
Synonym: Acetophenetidin
Target: COX
ML346
T3594
Synonym:
Target: HSP
UNC1215
T2379
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
LP99
T15784
Synonym:
Target: Epigenetic Reader Domain
ML179
T8954
Synonym: ML-179
Target: Others
Nitrobenzylthioinosine
T8551
Synonym: NBMPR
Target: AChR, Adenosine Receptor
Itaconate-alkyne
T41302
Synonym: ITalk
Target: Others
I-BRD9
T6859
Synonym: GSK602
Target: Epigenetic Reader Domain
Biotin-PEG3-azide
T14591
Synonym:
Target: Others, PROTAC Linker
GSK4112
T5045
Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452
Target: Autophagy
Safranin
TD0103
Synonym: Safranine T,Basic Red 2
Target: Others
Eprobemide
T5053
Synonym: LIS 630
Target: MAO, Monoamine Oxidase
Exiproben sodium salt
T31737
Synonym: DCH 21,DCH-21,DCH21
Target:
Exiproben
T31736
Synonym: DCH 21
Target:
Iprobenfos
T25539
Synonym: Ricid P,Kitazin P,Kitazin L,Ricid II
Target:
Probestin
T25987
Synonym:
Target:
Dihydrorhodamine 123
T18977
Synonym: DHR 123
Target: Others
NBD-Pen
T33602
Synonym: NBDPen,LipiRADICAL Green,NBD Pen,FDV-0042,Funakoshi
Target:
1 2 3 4 5 6 7 8 9 10
カタログ番号 製品名 別名 ターゲット
T4820 Maleimide 2,5-Pyrroledione Others
Maleimide (2,5-Pyrroledione) (2,5-Pyrroledone) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its b...
T20585 3-Acetylindole Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole Others
3-Acetylindole (3-Acetyl-1H-indole) can be used as a substituent and a probe to L-tryptophan for Sudlow site II.
T10023 1-Naphthol NSC 9586,Nako TRB,Furro ER Endogenous Metabolite
1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media.
T8712 1-Palmitoyl-sn-glycero-3-phosphocholine 1-Hexadecanoyl-sn-glycero-3-phosphocholine Others
1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine for fluorescent probe design
T40607 2,4,6-Trimethylphenol Mesitol Others
2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.
T7937 2-Amino-4'-fluorobenzophenone Others
2-Amino-4'-fluorobenzophenone is a derivative of benzophenone. It is used in the synthesis of p-fluorobenzoyl chloride and has also been used as a fluorescent probe for biochemical studies such as DNA and RNA detection.
T2910 Flavonol 3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone Others , Endogenous Metabolite
Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone...
T5S2361 Epiberberine ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe...
TN6661 4-(Dimethylamino)cinnamic acid
4-(Dimethylamino)cinnamic acid (DMACA) could be as charge transfer (ICT) probe.
T11683 Isoglycycoumarin Others
Isoglycycoumarin, a flavonoid derived from the roots of Glycyrrhiza uralensis, serves as a highly selective probe for human cytochrome P450 2A6.
T10194 7-Methylguanine Others
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method.
T3S0804 Worenine Worenin Others
Worenine (Worenin) is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA.
TN4062 Flavidin COX , Prostaglandin Receptor
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should have wide application in molecular detection, providing a ...
TN6663 Trans-4-(Trifluoromethyl)cinnamic acid
trans-4-(Trifluoromethyl)cinnamic acid is a photosensitizing compound. It is used as a reagent in the synthesis of various compounds, such as heterocyclic compounds and pharmaceuticals. It has also been used as a catalys...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04588 Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA-specific B cell probe (His) H1N1 Baculovirus Insect Cells
Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA-specific B cell probe (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is C3W5S1.
TMPY-04590 Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA-specific B cell probe Protein (His) H3N2 Baculovirus Insect Cells
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA-specific B cell probe Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58 kDa and the accession number is C6KNH7.
TMPY-04666 Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (His) H1N1 Baculovirus Insect Cells
Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58 kDa and the accession number is C3W5S1.
TMPY-04589 Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA-specific B cell probe Protein (His) H5N1 Baculovirus Insect Cells
Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA-specific B cell probe Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is AHJ...
TMPY-06927 Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA-specific B cell probe (Y108F, His & Avi), Biotinylated H1N1 Baculovirus Insect Cells
Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA-specific B cell probe (Y108F, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 59.58 kDa a...
TMPY-06948 Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated H1N1 Baculovirus Insect Cells
Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted mo...
TMPY-00209 PSAP/Prosaposin Protein, Rat, Recombinant (His) Rat HEK293 Cells
Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previ...
TMPY-04510 PSAP/Prosaposin Protein, Human, Recombinant (His) Human HEK293 Cells
Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previ...