検索結果

Search Results for " responses "

263

阻害剤

天然化合物

240

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T83705	BING TFA	Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
	BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gra...
T7954	YM976		PDE
	YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)		PDE
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src
T7511	Cyclo(his-pro)		NF-κB , Endogenous Metabolite
	Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.		NF-κB , Endogenous Metabolite
T3189	B7/CD28 interaction inhibitor 1	CTLA-4 inhibitor	Others
	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.		Others
T9079	Apostatin-1	Apt-1	Others
	Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.		Others
T3461	Losartan Carboxylic Acid	EXP-3174,E-3174	RAAS
	Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l...		RAAS
T4686	Simeprevir	TMC435,TMC-435350,Olysio	HCV Protease , SARS-CoV
	Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.		HCV Protease , SARS-CoV
T28540	Ripisartan	UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6	RAAS
	Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.		RAAS
T20571	Cis-PDA	cis PDA	GluR , NMDAR , iGluR
	cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.		GluR , NMDAR , iGluR
T11877	LR-90		Others
	LR-90, an advanced glycation end product (AGE) inhibitor, is utilized in diabetic animal model research. This compound effectively suppresses inflammatory responses in human monocytes.		Others
T9292	ALE-0540	ALE0540	Others , Trk receptor
	ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA, as well as signal transduction and biological responses mediated by TrkA receptors.		Others , Trk receptor
T21608L	β-Interleukin I (163-171), human Acetate	β-Interleukin I (163-171), human Acetate(106021-96-9 Free base)	Others
	β-Interleukin I (163-171), human Acetateis a peptide that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.		Others
T77761	BMS-502		Others
	BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune respo...		Others
T12241	Norbinaltorphimine dihydrochloride	nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride	Opioid Receptor
			Opioid Receptor
T35258	YM 16638	YM 638,YM-16638,YM16638	LTR
	YM 16638 is an orally active leukotriene (LT) antagonist with triglyceride-lowering and peroxisome-increasing effects that can be used to study antigen-induced early and late airway responses in allergic sheep.		LTR
T13932	TLR1		Others , MyD88
	TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.		Others , MyD88
T78181	MMP-7-IN-2		MMP , Others
	MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.		MMP , Others
T9119	SU0268		Others
	SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor. SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection.		Others
T2069L	TH287 hydrochloride		DNA/RNA Synthesis , MTH1
	TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.		DNA/RNA Synthesis , MTH1
T11492	GSK2983559 free acid		Others , RIP kinase
	GSK2983559 free acid is a specific and orally bioavailable inhibitor of receptor-interacting protein 2 (RIP2) kinase. It has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inf...		Others , RIP kinase
T22414	RBN012759		PARP
	RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.		PARP
T14377	AZD5423		Glucocorticoid Receptor
	AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.		Glucocorticoid Receptor
T14513	BBIQ		TLR
	BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of  59.1 nM for human TLR7.		TLR
T4613	Arg-Gly-Asp TFA (99896-85-2(free base))	RGD Trifluoroacetate,RGD	Integrin
	Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.		Integrin
T11630	IFN alpha-IFNAR-IN-1 hydrochloride		Others , IFNAR
			Others , IFNAR
T1076	Dexamethasone	MK 125,Prednisolone F,NSC 34521,Hexadecadrol	Glucocorticoid Receptor , Mitophagy , IL Receptor , SARS-CoV , Antibacterial , Antibiotic , Autophagy , Complement System
	Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced...
T36716	RO0270608		Integrin
	RO0270608, the active metabolite of R411, is an orally active dual α4β1/α4β7 integrin antagonist with anti-inflammatory activity that modulates inflammation and can be used in the study of allergic inflammatory responses...		Integrin
T19930	Nitrosoglutathione	S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO	RAAS , NO Synthase
	Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, i...		RAAS , NO Synthase
T19051	Reactive Blue 4		Others
	Reactive Blue 4 is an anthraquinone dye with phytotoxic, cytotoxic, and genotoxic. It is a single colorimetric chemosensor for the sequential determination of multiple analytes with different optical responses in aqueous...		Others
TP2209L	Xenin 8 acetate	Xenin 8 acetate (117442-28-1 Free base)	IGF-1R
			IGF-1R
T10432L	AZD-8529 mesylate		GluR
	AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 ...		GluR
T76699	Sabatolimab	MBG453,NVP-MBG453	Others
	Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selec...		Others
T19723	AMTB hydrochloride	AMTB	TRP/TRPV Channel
	AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...		TRP/TRPV Channel
T5489	Tryptophan, N-indol-3-ylacetyl- (6CI)	N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan	Glucosidase
	Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses. It may also be used in th...		Glucosidase
T31615	Elsibucol	AGI-1096,UNII-O7T92N1Y8T,AGI 1096	Antioxidant
	Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant, anti-inflammatory and anti-proliferative properties. It lowe...		Antioxidant
T2401	Alogliptin Benzoate	SYR 322,Alogliptin(SYR-322)benzoate	Ferroptosis , Proteasome , DPP-4
	Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the...		Ferroptosis , Proteasome , DPP-4
T13867	RH01386		Others
	RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ...		Others
T16478	PF-04447943	PF 04447943,Edelinontrine,PF04447943	PDE
	PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits ...		PDE
T9897	7-Methoxy-1-naphthaleneacetic acid		Others
	7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabid...		Others
T4206	E6446		TLR
	E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to ...		TLR
T50068	2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide		Others
	2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide is a compound used as a molecular structural unit, a cyclic dipeptide. It induces apoptosis, inhibits cell proliferation and modulates immune responses, an...		Others
T1435	Praziquantel	Pyquiton,Droncit,Biltricide	Calcium Channel , Antibiotic , Parasite
	Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculatur...		Calcium Channel , Antibiotic , Parasite
T31195	Dalcotidine	KU 1257,KU-1257	Histamine Receptor
	Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.The Ki value for binding to guinea pig cerebral cortex was 0.040 The KB value f...		Histamine Receptor
T0943	Carbamazepine	NSC 169864	Mitophagy , Sodium Channel , Autophagy
	Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysyna...		Mitophagy , Sodium Channel , Autophagy
T3614	Inosine pranobex	Groprinosin,Isoprinosine,Immunovir,Delimmun	IL Receptor , HIV Protease
	Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a...		IL Receptor , HIV Protease
T11800	L-803087		Somatostatin
			Somatostatin
T1281	Tropicamide	Ro 1-7683	AChR
	Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in ...		AChR
T78362	Transglutaminase	TG
	Transglutaminase (TG) is a thiolase that induces intermolecular cross-linking of proteins, by catalysing the formation of isopeptide bonds between the γ-carboxamide group of glutamine residues and the primary ε-amine gro...

Compounds

BING TFA

T83705

Synonym: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria

Target: IL Receptor, NOD

AMG-47a

T7123

Synonym:

Target: VEGFR, p38 MAPK, JAK, Src

Cyclo(his-pro)

T7511

Synonym:

Target: NF-κB, Endogenous Metabolite

B7/CD28 interaction inhibitor 1

T3189

Synonym: CTLA-4 inhibitor

Losartan Carboxylic Acid

T3461

Synonym: EXP-3174,E-3174

Target: RAAS

Simeprevir

T4686

Synonym: TMC435,TMC-435350,Olysio

Target: HCV Protease, SARS-CoV

Ripisartan

T28540

Synonym: UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6

Target: GluR, NMDAR, iGluR

Target: Others, Trk receptor

β-Interleukin I (163-171), human Acetate

T21608L

Synonym: β-Interleukin I (163-171), human Acetate(106021-96-9 Free base)

Norbinaltorphimine dihydrochloride

T12241

Synonym: nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride

Target: Opioid Receptor

YM 16638

T35258

Synonym: YM 638,YM-16638,YM16638

Target: Others, MyD88

Target: DNA/RNA Synthesis, MTH1

GSK2983559 free acid

T11492

Synonym:

Target: Others, RIP kinase

Target: Glucocorticoid Receptor

Arg-Gly-Asp TFA (99896-85-2(free base))

T4613

Synonym: RGD Trifluoroacetate,RGD

Target: Integrin

IFN alpha-IFNAR-IN-1 hydrochloride

T11630

Synonym:

Target: Others, IFNAR

Dexamethasone

T1076

Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System

Synonym: S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO

Target: RAAS, NO Synthase

Synonym: Xenin 8 acetate (117442-28-1 Free base)

Synonym: MBG453,NVP-MBG453

Target: TRP/TRPV Channel

Tryptophan, N-indol-3-ylacetyl- (6CI)

T5489

Synonym: N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan

Target: Glucosidase

Elsibucol

T31615

Synonym: AGI-1096,UNII-O7T92N1Y8T,AGI 1096

Target: Antioxidant

Alogliptin Benzoate

T2401

Synonym: SYR 322,Alogliptin(SYR-322)benzoate

Target: Ferroptosis, Proteasome, DPP-4

Synonym: PF 04447943,Edelinontrine,PF04447943

Target: PDE

7-Methoxy-1-naphthaleneacetic acid

2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide

Synonym: Pyquiton,Droncit,Biltricide

Target: Calcium Channel, Antibiotic, Parasite

Dalcotidine

T31195

Synonym: KU 1257,KU-1257

Target: Histamine Receptor

Carbamazepine

T0943

Synonym: NSC 169864

Target: Mitophagy, Sodium Channel, Autophagy

Inosine pranobex

T3614

Synonym: Groprinosin,Isoprinosine,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

カタログ番号	製品名	別名	ターゲット
T5826	Eupalinolide A		HSP
	Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.		HSP
T13502	3-Oxo-5β-cholanoic acid	Dehydrolithocholic acid	ROR
			ROR
TN2088	Platycodin D2		IL Receptor , HBV
	Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalaci...		IL Receptor , HBV
T3319	Scutellarein	4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin	SARS-CoV , Src , Autophagy
	Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.		SARS-CoV , Src , Autophagy
T13557	Ascr#5	Ascaroside C3	Others
	Ascr#5 (asc-ωC3) is a highly conserved ascoside analogue in Cryptococcus hidradii that modulates a variety of responses in Cryptococcus hidradii.		Others
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T5235	5-Methoxy-DL-tryptophan		Others , Endogenous Metabolite
	5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation.		Others , Endogenous Metabolite
TN1052	Lindleyin		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
TN6457	N-trans-caffeoyltyramine	Trans-N-Caffeoyltyramine,N-(E)-Caffeoyl-lambda-tyramine,N-cis-Caffeoyltyramine,Typheramide	Immunology/Inflammation related
	N-trans-caffeoyltyramine (Trans-N-Caffeoyltyramine) is a modulator of inflammatory responses and can be used in studies about treatment for chronic inflammatory diseases.		Immunology/Inflammation related
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
T67710	3-Indoleacrylic acid		Endogenous Metabolite
	3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by im...		Endogenous Metabolite
T2842	Tangeretin	NSC53909,Tangeritin,NSC618905	Apoptosis , Gamma-secretase
	Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notc...		Apoptosis , Gamma-secretase
TN2349	Taurodeoxycholate sodium salt	Sodium taurodeoxylate	Endogenous Metabolite
	Taurodeoxycholate sodium salt (Sodium taurodeoxylate) is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits various inflammatory...		Endogenous Metabolite
T5731	1-Kestose		Others , Endogenous Metabolite , Antibacterial
	1-Kestose shows significant anti-hydroxyl radical potential. 1-Kestose can promote intestinal Lactobacillus number, and influence the microorganisms as well as the intestinal and systemic immune responses.		Others , Endogenous Metabolite , Antibacterial
TN1879	Lucideric acid A	Lucidenic acid A	MMP , p38 MAPK , JNK
	Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.		MMP , p38 MAPK , JNK
T6S0657	Isorhynchophylline	IsoRhy,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline	Others
	1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of an...		Others
T5S0089	Kaempferol-3-O-glucorhamnoside	Kaempferol 3-glucorhamnoside	Antioxidant , p38 MAPK , NF-κB
	Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo[1]. Kaempferol-3-O-gl...		Antioxidant , p38 MAPK , NF-κB
T1614	Hydrocortisone	Cortisol	Glucocorticoid Receptor , Endogenous Metabolite
	Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio...		Glucocorticoid Receptor , Endogenous Metabolite
T4939	Indole-3-pyruvic acid	3-(3-Indolyl)-2-oxopropanoic acid	Others
	Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta...		Others
T13555	Ascr#2	Ascaroside C6	Others
	Ascr#2 (asc-C6-MK) is a glycoside analogue in Cryptococcus hidradii that promotes dauer formation.Ascr#2 mixtures with ascr#3 at low concentrations act as a male elicitor and can be used to detect population density.Ascr...		Others
T5S0993	Kurarinone		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
TN1134	Euscaphic acid		Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T1004	6-Benzylaminopurine	6-BAP,N6-Benzyladenine,BA,Benzyladenine	Others
	6-Benzylaminopurine (6-BAP), benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell divisi...		Others
T4928	L-Kynurenine	(S)-Kynurenine	AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
	L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...		AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
T5S1895	Norisoboldine	Laurelliptine,(+)-Laurelliptine	MAPK , Adenosine Receptor
	1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo...		MAPK , Adenosine Receptor
TN6774	Emodin 6-O-β-D-glucoside	Glucoemodin	Others
	Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ...		Others
T3S0364	L-Arginine	L-Arg,(S)-(+)-Arginine	IL Receptor , Endogenous Metabolite , NO Synthase
	1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...		IL Receptor , Endogenous Metabolite , NO Synthase
T5S1286	(+)-Columbianetin	(S)-Columbianetin,Columbianetin	Antifungal
	(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect...		Antifungal
T3386	Kaempferitrin	Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside	cell cycle arrest , Glucokinase , IGF-1R
	Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...		cell cycle arrest , Glucokinase , IGF-1R
T4868	Gamma-Linolenic acid	gamolenic acid,γ-Linolenic acid	Endogenous Metabolite
	gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r...		Endogenous Metabolite
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T5S1177	Aloin B	Isobarbaloin	Others
	Aloin B (Isobarbaloin) is an isomer of aloin.1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new ...		Others
T1611	Isotretinoin	13-cis-Retinoic acid	Retinoid Receptor , Endogenous Metabolite , Autophagy
	Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...		Retinoid Receptor , Endogenous Metabolite , Autophagy
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T4S2326	Cornuside	7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside	ERK , p38 MAPK , NF-κB , JNK
	1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...		ERK , p38 MAPK , NF-κB , JNK
T35749	Thymohydroquinone	Thymoquinol	Antioxidant , Reactive Oxygen Species
	Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulate...		Antioxidant , Reactive Oxygen Species
TN4882	Quinine HCl		Adrenergic Receptor
	Quinine HCl produces alpha-adrenergic blockade. Quinine modifies catecholamine- and calcium-induced myocardial contractile force responses.		Adrenergic Receptor
T39179	β-Tomatine
	β-Tomatine, a derivative of α-tomatine, is a fungitoxic compound that efficiently inhibits plant defense responses.
TN4804	Platycoside A		Antifection
	Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mi...		Antifection
TN3482	Bakkenolide B		NOS , COX
	Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.		NOS , COX
T20217	Grandiflorenic acid
	Grandiflorenic acid can reproduce the uterine responses induced by aqueous extract of zoapatle leaves. It is suggested that grandiflorenic acid may have an antifertility effect.
T83600	(+)-Dihydrocarvone
	(+)-Dihydrocarvone significantly stimulates the antennal responses of Apis mellifera and affects the foraging preferences of these bees for tomatoes [1].
T13968	Xanthoplanine		Others
	Xanthoplanine is a natural product isolated from theroot of Xylopia parviflora, and inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors (IC50 of 9 μM and 5 μMc for alpha7 and alpha4beta2,respect...		Others
T61171	Cyclo(his-pro) TFA
	Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the...
TN2181	Sarmentosin		Others
	Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice. It shows a good effect in lowering serum gluta...		Others
TN4420	Latifolin	檀木	IL Receptor , IκB/IKK , TNF , NOS , NF-κB , COX , Nrf2 , Prostaglandin Receptor , Antifection , Autophagy
	Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-ÎºB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme,...
T38838	QS-21	Stimulon,QS-21
	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q...
T82277	GM1a Ganglioside oligosaccharide
	GM1a Ganglioside oligosaccharide, a semisynthetic derivative of ganglioside GM1, serves as the natural receptor for cholera toxin and is crucial for both general growth regulation and the coupling of hormone-induced resp...
------------------------ More ------------------------

天然物製品

3-Oxo-5β-cholanoic acid

T13502

Synonym: Dehydrolithocholic acid

Target: IL Receptor, HBV

Scutellarein

T3319

Synonym: 4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin

Target: SARS-CoV, Src, Autophagy

Ascr#5

T13557

Synonym: Ascaroside C3

Target: Others

Corticosterone

T0948L

Synonym: 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

5-Methoxy-DL-tryptophan

T5235

Synonym:

Target: Others, Endogenous Metabolite

Lindleyin

TN1052

Synonym:

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

N-trans-caffeoyltyramine

TN6457

Synonym: Trans-N-Caffeoyltyramine,N-(E)-Caffeoyl-lambda-tyramine,N-cis-Caffeoyltyramine,Typheramide

Target: Immunology/Inflammation related

DL-Syringaresinol

TN1594

Synonym: (±)-Syringaresinol

Target: Antioxidant, Antifungal

3-Indoleacrylic acid

T67710

Synonym:

Target: Endogenous Metabolite

Tangeretin

T2842

Synonym: NSC53909,Tangeritin,NSC618905

Target: Apoptosis, Gamma-secretase

Taurodeoxycholate sodium salt

TN2349

Synonym: Sodium taurodeoxylate

Target: Endogenous Metabolite

1-Kestose

T5731

Synonym:

Target: Others, Endogenous Metabolite, Antibacterial

Lucideric acid A

TN1879

Synonym: Lucidenic acid A

Target: MMP, p38 MAPK, JNK

Isorhynchophylline

T6S0657

Synonym: IsoRhy,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline

Target: Others

Kaempferol-3-O-glucorhamnoside

T5S0089

Synonym: Kaempferol 3-glucorhamnoside

Target: Antioxidant, p38 MAPK, NF-κB

Hydrocortisone

T1614

Synonym: Cortisol

Target: Glucocorticoid Receptor, Endogenous Metabolite

Indole-3-pyruvic acid

T4939

Synonym: 3-(3-Indolyl)-2-oxopropanoic acid

Target: Others

Ascr#2

T13555

Synonym: Ascaroside C6

Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT

Euscaphic acid

TN1134

Synonym:

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

6-Benzylaminopurine

T1004

Synonym: 6-BAP,N6-Benzyladenine,BA,Benzyladenine

Target: Others

L-Kynurenine

T4928

Synonym: (S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Norisoboldine

T5S1895

Synonym: Laurelliptine,(+)-Laurelliptine

Target: MAPK, Adenosine Receptor

Emodin 6-O-β-D-glucoside

Synonym: L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

(+)-Columbianetin

T5S1286

Synonym: (S)-Columbianetin,Columbianetin

Target: Antifungal

Kaempferitrin

T3386

Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside

Target: cell cycle arrest, Glucokinase, IGF-1R

gamma-Linolenic acid

T4868

Synonym: gamolenic acid,γ-Linolenic acid

Target: Endogenous Metabolite

Synonym: Isobarbaloin

Target: Others

Isotretinoin

T1611

Synonym: 13-cis-Retinoic acid

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

Cornuside

T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

Thymohydroquinone

T35749

Synonym: Thymoquinol

Target: Antioxidant, Reactive Oxygen Species

Quinine HCl

TN4882

Synonym:

Target: Adrenergic Receptor

Target: IL Receptor, IκB/IKK, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Antifection, Autophagy

QS-21

T38838

Synonym: Stimulon,QS-21

Target:

GM1a Ganglioside oligosaccharide

T82277

Synonym:

Target:

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00047	IFN gamma Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPJ-00735	PDGF-BB Protein, Human, Recombinant	Human	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00864	VEGF165 Protein, Human, Recombinant	Human	HEK293 Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-05510	BDNF Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPJ-00042	TSLP Protein, Human, Recombinant	Human	E. coli
	Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-03443	NDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differ...
TMPK-00123	CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated	Human	HEK293 Cells
	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendri...
TMPH-01541	ITIH4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
TMPH-01542	ITIH4 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
TMPJ-00446	CD32A Protein, Human, Recombinant (R167, His)	Human	HEK293 Cells
	Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (C...
TMPJ-00030	IL-1F10 Protein, Human, Recombinant	Human	E. coli
	Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate immune responses. IL-1F10 was expressed in fetal skin, spleen ...
TMPK-00698	AGR2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progressi...
TMPH-02688	Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	This enzyme is probably necessary for target cell lysis in cell-mediated immune responses. Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. Th...
TMPK-00598	Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-depende...
TMPK-01231	CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps...
TMPH-01714	CHRM1 Protein, Human, Recombinant (His)	Human	E. coli
	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TMPH-03338	CHRM1 Protein, Rat, Recombinant (His)	Rat	E. coli
	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TMPH-01717	CHRM5 Protein, Human, Recombinant (His)	Human	E. coli
	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TMPK-00696	PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)	Human	Baculovirus Insect Cells
	The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-...
TMPK-01539	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01192	Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)	Varicella-zoster virus (strain Oka vaccine)	HEK293 Cells
	VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antib...
TMPK-01546	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01497	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01449	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01500	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPJ-00629	TIGIT Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane...
TMPH-02208	TRAF3 Protein, Human, Recombinant	Human	E. coli
	Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon....
TMPH-01716	CHRM3 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TMPK-01499	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01331	TSLPR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of t...
TMPK-01513	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01448	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi)	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01543	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01040	NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role i...
TMPK-01230	CLEC2D Protein, Human, Recombinant (hFc & Avi)	Human	HEK293 Cells
	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps...
TMPH-03508	IpaH9.8 Protein, Shigella flexneri, Recombinant (His)	Shigella flexneri	P. pastoris (Yeast)
	Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway and modulates the acute i...
TMPH-02829	Phospholipase D3/PLD3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotid...
TMPK-00791	Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPH-03332	OPN4 Protein, Rat, Recombinant (His)	Rat	E. coli
	Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved i...
------------------------ More ------------------------

IFN gamma Protein, Human, Recombinant (His & Avi)

TMPK-00047

Species: Human

Expression System: HEK293 Cells

PDGF-BB Protein, Human, Recombinant

TMPJ-00735

Species: Human

Expression System: E. coli

VEGF165 Protein, Human, Recombinant

TMPJ-00864

Species: Human

Expression System: HEK293 Cells

STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus Insect Cells

BDNF Protein, Mouse, Recombinant (His)

TMPY-05510

Species: Mouse

Expression System: HEK293 Cells

TPSAB1 Protein, Human, Recombinant (His)

TMPJ-01204

Species: Human

Expression System: HEK293 Cells

TLR4 Protein, Human, Recombinant (His)

TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TMPJ-00137

Species: Human

Expression System: HEK293 Cells

IL-4R alpha Protein, Mouse, Recombinant (hFc)

TMPJ-00387

Species: Mouse

Expression System: HEK293 Cells

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

TSLP Protein, Human, Recombinant

TMPJ-00042

Species: Human

Expression System: E. coli

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus Insect Cells

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

TMPY-02219

Species: H1N1

Expression System: E. coli

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

NDRG1 Protein, Human, Recombinant (His)

TMPY-03443

Species: Human

Expression System: E. coli

CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated

TMPK-00123

Species: Human

Expression System: HEK293 Cells

ITIH4 Protein, Human, Recombinant (His)

TMPH-01541

Species: Human

Expression System: P. pastoris (Yeast)

ITIH4 Protein, Human, Recombinant (His & SUMO)

TMPH-01542

Species: Human

Expression System: E. coli

CD32A Protein, Human, Recombinant (R167, His)

TMPJ-00446

Species: Human

Expression System: HEK293 Cells

IL-1F10 Protein, Human, Recombinant

TMPJ-00030

Species: Human

Expression System: E. coli

AGR2 Protein, Mouse, Recombinant (His)

TMPK-00698

Species: Mouse

Expression System: E. coli

Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)

TMPH-02688

Species: Mouse

Expression System: E. coli

Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00598

Species: Human

Expression System: HEK293 Cells

CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPK-01231

Species: Human

Expression System: HEK293 Cells

CHRM1 Protein, Human, Recombinant (His)

TMPH-01714

Species: Human

Expression System: E. coli

CHRM1 Protein, Rat, Recombinant (His)

TMPH-03338

Species: Rat

Expression System: E. coli

CHRM5 Protein, Human, Recombinant (His)

TMPH-01717

Species: Human

Expression System: E. coli

PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

TMPK-00696

Species: Human

Expression System: Baculovirus Insect Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01539

Species: Human

Expression System: HEK293 Cells

Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)

TMPK-01192

Species: Varicella-zoster virus (strain Oka vaccine)

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01546

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01497

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

TMPK-01449

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01500

Species: Human

Expression System: HEK293 Cells

TIGIT Protein, Cynomolgus, Recombinant (His)

TMPJ-00629

Species: Cynomolgus

Expression System: HEK293 Cells

TRAF3 Protein, Human, Recombinant

TMPH-02208

Species: Human

Expression System: E. coli

CHRM3 Protein, Human, Recombinant (B2M & His)

TMPH-01716

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01499

Species: Human

Expression System: HEK293 Cells

TSLPR Protein, Cynomolgus, Recombinant (His)

TMPK-01331

Species: Cynomolgus

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01513

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi)

TMPK-01448

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi)

TMPK-01543

Species: Human

Expression System: HEK293 Cells

NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)

TMPK-01040

Species: Cynomolgus

Expression System: HEK293 Cells

CLEC2D Protein, Human, Recombinant (hFc & Avi)

TMPK-01230

Species: Human

Expression System: HEK293 Cells

IpaH9.8 Protein, Shigella flexneri, Recombinant (His)

TMPH-03508

Species: Shigella flexneri

Expression System: P. pastoris (Yeast)

Phospholipase D3/PLD3 Protein, Mouse, Recombinant (His)

TMPH-02829

Species: Mouse

Expression System: E. coli

Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)

TMPK-00791

Species: Human

Expression System: HEK293 Cells

CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

TMPH-03267

Species: Rat

Expression System: E. coli

OPN4 Protein, Rat, Recombinant (His)

TMPH-03332

Species: Rat

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L3200	Autophagy Compound Library	1248 compounds
	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L1580	GPCR Compound Library Plus	338 compounds
	Well-chosen 338 GPCR targeting compounds with unique structures;
L2150	Anti-Cancer Drug Library	3080 compounds
	A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L3600	Cytokine Inhibitor Library	604 compounds
	A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L2160	Anti-Cancer Active Compound Library	3188 compounds
	A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L1500	GPCR Compound Library	1940 compounds
	A unique collection of 1940 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;
L2100	Anti-Cancer Compound Library	7234 compounds
	A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2120	Anti-Cancer Clinical Compound Library	2545 compounds
	A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L2110	Anti-Cancer Approved Drug Library	1779 compounds
	A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L4010	Bioactive Compounds Library Max	22555 compounds
	A collection of 22555 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification.
L4700	Immunology/Inflammation Compound Library	4720 compounds
	A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening.
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9420	Exosome Compound Library	76 compounds
	76 exosome-related compounds that can be used for high-throughput and high-content screening.
L2190	Anti-Lung Cancer Compound Library	1702 compounds
	A unique collection of 1702 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study；
L2170	Immuno-Oncology Compound Library	449 compounds
	A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening；