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ターゲット

Tyrosine Kinases ROS Kinase

582

阻害剤

天然化合物

117

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T60220	ROS kinases-IN-1		ROS Kinase
	ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.		ROS Kinase
T30580	BRD4-Kinases-IN-3	BRD4 kinases inhibitor 3,BRD4-Kinases inhibitor-3
	BRD4-Kinases-IN-3 is a dual BRD4-Kinases inhibitor that can be used as a value-added multi-targeted chemical probe for cancer therapy.
T74671	ROS kinases-IN-2		ROS Kinase
	ROS kinases-IN-2 is a potent ROS kinase inhibitor with an inhibition rate of 21.53% measured at 10 μM.ROS kinases-IN-2 has potential anticancer activity and can be used to study abnormal cell growth.		ROS Kinase
T62484	Aurora Kinases-IN-2
	Aurora Kinases-IN-2 (compound 12Aj) is a potent inhibitor of Aurora kinases, acting on Aurora A (IC50: 90 nM) and Aurora B (IC50: 152 nM). Aurora Kinases-IN-2 can be used in cancer research.
T72504	Aurora Kinases-IN-3
	Aurora Kinases-IN-3, an orally active inhibitor of AURKB, suppresses AURKB activity by hindering its mitotic localization rather than by inhibiting its phosphorylation of H3 at Ser10.
T78753	Aurora Kinases-IN-4		Aurora Kinase
	Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM. It demonstrates cell proliferation inhibition in SJSA-1, MDA-MB-231, A549, and HeLa cell lines ...		Aurora Kinase
T14860	CaMKII-IN-1		CaMK , Autophagy
	CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, p38a, MLCK, Akt1, and PKC.		CaMK , Autophagy
T16967	T-00127_HEV1		PI4K
	T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM).		PI4K
TQ0009	UCB9608		PI4K
	UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.		PI4K
T12454	PI-273		Apoptosis , PI4K
	PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells		Apoptosis , PI4K
T16125	MMV390048		Parasite , PI4K
	MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. fal...		Parasite , PI4K
T16530	BF738735		Antiviral , PI4K
			Antiviral , PI4K
T2697	KN-93		CaMK , Autophagy
	KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.		CaMK , Autophagy
TQ0137	A-484954	A 484954	CaMK , Parasite , Autophagy
	A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.		CaMK , Parasite , Autophagy
TP2310	Autocamtide-2-related inhibitory peptide		CaMK , Autophagy
	Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.		CaMK , Autophagy
T10599	BRAF inhibitor		Raf
	BRAF inhibitor is an inhibitor of B-Raf.		Raf
T6605	NH125		CaMK , Virus Protease , PKA , Antibacterial , PKC , Autophagy , Antifungal
	NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
T12468	PI4KIIIbeta-IN-10		PI3K , PI4K
	PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).		PI3K , PI4K
T2616	PIK-93	PIK 93	ATM/ATR , DNA-PK , Virus Protease , PI3K , Carbonic Anhydrase , PI4K , mTOR , HSV
	PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T11224	Rineterkib	ERK-IN-1	ERK , Raf
			ERK , Raf
T5421	KDU691		Parasite , PI4K
	KDU691 is a PI4K inhibitor.		Parasite , PI4K
T3546	STO-609	STO 609	CaMK , AMPK , Autophagy
	STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL).		CaMK , AMPK , Autophagy
T2694	KN-62		CaMK , P2X Receptor , Autophagy
	KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.		CaMK , P2X Receptor , Autophagy
T12469	PI4KIIIbeta-IN-9		PI3K , PI4K
	PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .		PI3K , PI4K
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T4220	BQR-695	BQR695,NVP-BQR695	PI3K , Parasite , PI4K
	BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.		PI3K , Parasite , PI4K
T27499	GSK-A1		HCV Protease , PI4K
	GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.		HCV Protease , PI4K
TQ0048	BI-882370		Raf
	BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.		Raf
T2295	SB-590885		Raf
	SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The selectivity of SB590885 for B-Raf is 11-fold greater over c-Raf, no acts to other human kinases.		Raf
T10667	Calmidazolium chloride	R 24571	CaMK , Autophagy
			CaMK , Autophagy
T15794	LUT014		Raf
	LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.		Raf
T5358	Longdaysin		ERK , Casein Kinase , CDK
	Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 µM). It also can inhibit ERK2 (IC50: 52 µM).		ERK , Casein Kinase , CDK
T4133	CCT196969		Raf , Src
	CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.		Raf , Src
T3711	RAF709		Raf
	RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.		Raf
T4523	TP-3654		Pim
	TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).		Pim
T16429	GNE 2861		PAK
	GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.		PAK
T2473	PLX-4720	PLX4720	Raf
	PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations).		Raf
T11342L	G-5555		PAK
			PAK
T6840	FRAX486		PAK
	FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.		PAK
T5172	AZ304		c-Fms , Raf , p38 MAPK , Autophagy
	AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).		c-Fms , Raf , p38 MAPK , Autophagy
T6014	FRAX597		PAK
	FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).		PAK
T6839	FRAX1036		PAK
	FRAX-1036 is a effective and selective PAK1 inhibitor.		PAK
T6318	AZ 628		Apoptosis , Raf
	AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.		Apoptosis , Raf
TQ0005	KO-947		ERK
	KO-947 is a potent and specific inhibitor of ERK1/2 kinases.		ERK
T6066	SCH772984		ERK , MEK
	SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.		ERK , MEK
T10479	BAY885		ERK
	BAY885 is a new ERK5 inhibitor.		ERK
T14360	AX-15836		ERK
	AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).		ERK
T9305	Necroptosis-IN-1		RIP kinase
	Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.		RIP kinase
T14894	CC-90003		ERK
	CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.		ERK
T2300	AZD1208		Apoptosis , Pim , Autophagy
	AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.		Apoptosis , Pim , Autophagy

Compounds

Synonym: BRD4 kinases inhibitor 3,BRD4-Kinases inhibitor-3

Aurora Kinases-IN-2

T62484

Synonym:

Target:

Aurora Kinases-IN-3

T72504

Synonym:

Target:

Aurora Kinases-IN-4

T78753

Synonym:

Target: Aurora Kinase

CaMKII-IN-1

T14860

Synonym:

Target: CaMK, Autophagy

Target: Apoptosis, PI4K

MMV390048

T16125

Synonym:

Target: Parasite, PI4K

BF738735

T16530

Synonym:

Target: Antiviral, PI4K

KN-93

T2697

Synonym:

Target: CaMK, Autophagy

A-484954

TQ0137

Synonym: A 484954

Target: CaMK, Parasite, Autophagy

Autocamtide-2-related inhibitory peptide

TP2310

Synonym:

Target: CaMK, Autophagy

Target: CaMK, Virus Protease, PKA, Antibacterial, PKC, Autophagy, Antifungal

Target: ATM/ATR, DNA-PK, Virus Protease, PI3K, Carbonic Anhydrase, PI4K, mTOR, HSV

Target: Parasite, PI4K

STO-609

T3546

Synonym: STO 609

Target: CaMK, AMPK, Autophagy

KN-62

T2694

Synonym:

Target: CaMK, P2X Receptor, Autophagy

Synonym: BQR695,NVP-BQR695

Target: PI3K, Parasite, PI4K

GSK-A1

T27499

Synonym:

Target: HCV Protease, PI4K

Calmidazolium chloride

T10667

Synonym: R 24571

Target: CaMK, Autophagy

Target: ERK, Casein Kinase, CDK

Target: c-Fms, Raf, p38 MAPK, Autophagy

Target: Apoptosis, Raf

Target: Apoptosis, Pim, Autophagy

カタログ番号	製品名	別名	ターゲット
TQ0201	Hispidulin	Dinatin	Pim
	Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).		Pim
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
T8114	Quercetagetin	6-Hydroxyquercetin	Pim
	Quercetagetin (6-Hydroxyquercetin) (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).		Pim
T3856	Tenuifoliside A		ERK , Others
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.		ERK , Others
T3857	Magnolin	(+)-Magnolin	ERK
	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.		ERK
T3844	Deltonin		ERK , Others , Akt , Endogenous Metabolite
	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).		ERK , Others , Akt , Endogenous Metabolite
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
T6947	Piperlongumine	PPLGM,Piplartine	Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
TN1410	Asperulosidic acid	ASPA	ERK , NF-κB
	Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...		ERK , NF-κB
TL0016	Sulforaphene		Apoptosis , ERK , EGFR , NF-κB
	Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...		Apoptosis , ERK , EGFR , NF-κB
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T6S0619	Pachymic acid	3-O-Acetyltumulosic acid	ERK , Akt
	Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.		ERK , Akt
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
TMS2181	Trans-Zeatin	(E)-Zeatin	ERK , MEK , Endogenous Metabolite
	trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.		ERK , MEK , Endogenous Metabolite
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T0646	5-Aminosalicylic Acid	Mesalazine,5-ASA,Mesalamine	NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
	5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
T7939	Fingolimod	FTY-720A,FTY-720	S1P Receptor , PAK , LPL Receptor
	Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).		S1P Receptor , PAK , LPL Receptor
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
T4291	(+)-Isocorydine hydrochloride	Isocorydine HCl	Serine/threonin kinase , Tyrosinase
	(+)-Isocorydine hydrochloride (Isocorydine HCl) is a eukaryote protein kinases Inhibitor.		Serine/threonin kinase , Tyrosinase
T22974	Methyl 2,5-dihydroxycinnamate		EGFR
	EGF receptor-associated tyrosine kinases inhibitor		EGFR
T6169	Indirubin	Indigopurpurin,Indigo red,NSC 105327,Couroupitine B	Apoptosis , Raf , GSK-3 , CDK
	Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.		Apoptosis , Raf , GSK-3 , CDK
T5057	DL-O-Phosphoserine	DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP	Others , Endogenous Metabolite
	DL-O-Phosphoserine (DL-SOP), a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling ...		Others , Endogenous Metabolite
T3S2390	Caftaric acid	trans-Caftaric acid	Others
	Caftaric acid (trans-Caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by Src family kinases.		Others
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
T2336	Vitamin K2	Menatetrenone	Endogenous Metabolite
	Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several...		Endogenous Metabolite
Fr16741	Oxindole	Indolin-2-one	Others , HIV Protease
	Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ...		Others , HIV Protease
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T0610	Piceatannol	trans-Piceatannol,Astringenin	Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy
	Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is...
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel
TN3042	4-Hydroxycinnamamide		ATPase , EGFR , Potassium Channel , p38 MAPK , Calcium Channel , Sodium Channel , AMPK
	4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
T15637	K-252b		PKC
	K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely...		PKC
TN2775	2-Methoxystypandrone		MMP , BCL , IκB/IKK , GSK-3 , TNF , NOS , NF-κB , Wnt/beta-catenin , COX , JAK , STAT
	2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-ÎºB signaling to limit the inflammation and oxidative stress for preservation of BBB integrit...

天然物製品

Target: ERK, AMPK, STAT

Quercetagetin

T8114

Synonym: 6-Hydroxyquercetin

Synonym: (+)-Magnolin

Target: ERK, Others, Akt, Endogenous Metabolite

Epieriocalyxin A

TN3967

Synonym:

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Piperlongumine

T6947

Synonym: PPLGM,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Target: Apoptosis, ERK, EGFR, NF-κB

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Loureirin B

T3876

Synonym:

Target: PAI-1, ERK, Potassium Channel, JNK

Pachymic acid

T6S0619

Synonym: 3-O-Acetyltumulosic acid

Target: ERK, NF-κB, COX, PGE Synthase

trans-Zeatin

TMS2181

Synonym: (E)-Zeatin

Target: ERK, MEK, Endogenous Metabolite

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

5-Aminosalicylic Acid

T0646

Synonym: Mesalazine,5-ASA,Mesalamine

Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Endogenous Metabolite, PAK, PPAR

Fingolimod

T7939

Synonym: FTY-720A,FTY-720

Target: S1P Receptor, PAK, LPL Receptor

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Tauroursodeoxycholate

T2532

Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

(+)-Isocorydine hydrochloride

T4291

Synonym: Isocorydine HCl

Target: Serine/threonin kinase, Tyrosinase

Methyl 2,5-dihydroxycinnamate

Synonym: Indigopurpurin,Indigo red,NSC 105327,Couroupitine B

Target: Apoptosis, Raf, GSK-3, CDK

DL-O-Phosphoserine

T5057

Synonym: DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP

Target: Others, Endogenous Metabolite

Caftaric acid

T3S2390

Synonym: trans-Caftaric acid

Target: Others

Isoacteoside

T3892

Synonym: Isoverbascoside

Target: NF-κB

Vitamin K2

T2336

Synonym: Menatetrenone

Target: Endogenous Metabolite

Oxindole

Fr16741

Synonym: Indolin-2-one

Target: Others, HIV Protease

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Piceatannol

T0610

Synonym: trans-Piceatannol,Astringenin

Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

8-Gingerol

T6S1684

Synonym:

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

4-Hydroxycinnamamide

TN3042

Synonym:

Target: ATPase, EGFR, Potassium Channel, p38 MAPK, Calcium Channel, Sodium Channel, AMPK

Target: MMP, BCL, IκB/IKK, GSK-3, TNF, NOS, NF-κB, Wnt/beta-catenin, COX, JAK, STAT

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPK-00474	IL-22RA1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component o...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04378	MAPKAPK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases ...
TMPY-04566	CAMKV Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase...
TMPK-00876	G-CSFR/CD114 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) ...
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac...
TMPY-04407	LOK Protein, Human, Recombinant (His)	Human	E. coli
	Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPY-04546	CLK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Dual specificity protein kinase CLK3, also known as CDC-like kinase 3, and CLK3, is a member of CMGC Ser/Thr protein kinase family and Lammer subfamily. Mammalian CLK is the prototype for a family of dual specificity ...
TMPY-04544	MEK2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/...
TMPY-04402	CSNK1G1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are ...
TMPY-02264	LRIG1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein ...
TMPY-03442	MOB4A/MOB1B Protein, Human, Recombinant (GST)	Human	E. coli
	MST1 and MST2 are the mammalian Ste2-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. Overexpression of MST1 or MST2 in mammalian ...
TMPH-03458	STE11 Protein, S. cerevisiae, Recombinant	Saccharomyces cerevisiae	E. coli
	Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KS...
TMPY-05095	RAF1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct...
TMPH-02278	PTPN5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. PTPN5 Protein, Human, Recombinant (His & SUMO) i...
TMPH-02272	JAK1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ...
TMPH-02758	LIMS1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell sur...
TMPY-04461	TRIB3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T...
TMPY-04558	NEK7 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) pro...
TMPY-04460	OXSR1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPY-04397	PAK-3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are si...
TMPH-02273	JAK1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ...
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosph...
TMPH-01581	KRT1 Protein, Human, Recombinant (His)	Human	E. coli
	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/H...
TMPH-02905	TRPC1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled recep...
TMPY-04260	P38 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPH-02209	TRAF5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation o...
TMPH-02961	JAK1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ...
TMPJ-00315	ACVR2A Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation fact...
TMPJ-00406	EphA8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EphA8, also known as Hek3 and Eek, is a 120 kDa glycosylated member of the Eph family of transmembrane receptor tyrosine kinases. The A and B classes of Eph proteins are distinguished by Ephrin ligand binding preference ...
TMPY-04443	NEK3 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of...
TMPY-04542	CDK2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas...
TMPJ-01335	MOB1A Protein, Human, Recombinant (His)	Human	E. coli
	MOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting prolif...
TMPJ-00224	EFNB2 Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors...
TMPH-01265	PELI3 Protein, Human, Recombinant (His)	Human	E. coli
	E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Me...
TMPY-04423	CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular r...
TMPY-03510	Cbl-c Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C...
TMPK-00577	ROR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPK-00579	ROR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPH-01699	SMAD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t...
TMPH-02126	SORBS2 Protein, Human, Recombinant (His)	Human	E. coli
	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of AB...
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TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

TMPY-02953

Species: Human

Expression System: HEK293 Cells

IL-22RA1 Protein, Cynomolgus, Recombinant (His)

TMPK-00474

Species: Cynomolgus

Expression System: HEK293 Cells

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

PTP1B Protein, Human, Recombinant (His)

TMPY-04125

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

IL-33 Protein, Mouse, Recombinant

TMPJ-01210

Species: Mouse

Expression System: E. coli

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: HEK293 Cells

C-ABL/ABL1 Protein, Human, Recombinant (GST)

TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

MAPKAPK3 Protein, Human, Recombinant (GST)

TMPY-04378

Species: Human

Expression System: Baculovirus Insect Cells

CAMKV Protein, Human, Recombinant (His & GST)

TMPY-04566

Species: Human

Expression System: Baculovirus Insect Cells

G-CSFR/CD114 Protein, Mouse, Recombinant (His)

TMPK-00876

Species: Mouse

Expression System: HEK293 Cells

SHP-2 Protein, Mouse, Recombinant (His)

TMPY-03125

Species: Mouse

Expression System: HEK293 Cells

LOK Protein, Human, Recombinant (His)

TMPY-04407

Species: Human

Expression System: E. coli

YES1 Protein, Human, Recombinant (His & GST)

TMPY-04411

Species: Human

Expression System: Baculovirus Insect Cells

CLK3 Protein, Human, Recombinant (GST)

TMPY-04546

Species: Human

Expression System: Baculovirus Insect Cells

MEK2 Protein, Human, Recombinant (GST)

TMPY-04544

Species: Human

Expression System: Baculovirus Insect Cells

CSNK1G1 Protein, Human, Recombinant (His & GST)

TMPY-04402

Species: Human

Expression System: Baculovirus Insect Cells

LRIG1 Protein, Mouse, Recombinant (His)

TMPY-02264

Species: Mouse

Expression System: HEK293 Cells

MOB4A/MOB1B Protein, Human, Recombinant (GST)

TMPY-03442

Species: Human

Expression System: E. coli

STE11 Protein, S. cerevisiae, Recombinant

TMPH-03458

Species: Saccharomyces cerevisiae

Expression System: E. coli

RAF1 Protein, Human, Recombinant (His & GST)

TMPY-05095

Species: Human

Expression System: Baculovirus Insect Cells

PTPN5 Protein, Human, Recombinant (His & SUMO)

TMPH-02278

Species: Human

Expression System: E. coli

JAK1 Protein, Human, Recombinant (E. coli, His)

TMPH-02272

Species: Human

Expression System: E. coli

LIMS1 Protein, Mouse, Recombinant (His)

TMPH-02758

Species: Mouse

Expression System: Baculovirus Insect Cells

TRIB3 Protein, Human, Recombinant (GST)

TMPY-04461

Species: Human

Expression System: Baculovirus Insect Cells

NEK7 Protein, Human, Recombinant (His & GST)

TMPY-04558

Species: Human

Expression System: Baculovirus Insect Cells

OXSR1 Protein, Human, Recombinant (GST)

TMPY-04460

Species: Human

Expression System: Baculovirus Insect Cells

PAK-3 Protein, Human, Recombinant (His)

TMPY-04397

Species: Human

Expression System: Baculovirus Insect Cells

JAK1 Protein, Human, Recombinant (His)

TMPH-02273

Species: Human

Expression System: P. pastoris (Yeast)

PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

TMPH-02277

Species: Human

Expression System: E. coli

KRT1 Protein, Human, Recombinant (His)

TMPH-01581

Species: Human

Expression System: E. coli

TRPC1 Protein, Mouse, Recombinant (His)

TMPH-02905

Species: Mouse

Expression System: E. coli

p38 Protein, Human, Recombinant (His)

TMPY-04260

Species: Human

Expression System: Baculovirus Insect Cells

hFcgR4 Protein, Mouse, Recombinant (His)

TMPJ-00534

Species: Mouse

Expression System: HEK293 Cells

TRAF5 Protein, Human, Recombinant (His & SUMO)

TMPH-02209

Species: Human

Expression System: E. coli

JAK1 Protein, Mouse, Recombinant (His)

TMPH-02961

Species: Mouse

Expression System: E. coli

ACVR2A Protein, Human, Recombinant (hFc & His)

TMPJ-00315

Species: Human

Expression System: HEK293 Cells

EphA8 Protein, Human, Recombinant (His)

TMPJ-00406

Species: Human

Expression System: HEK293 Cells

NEK3 Protein, Mouse, Recombinant (His & GST)

TMPY-04443

Species: Mouse

Expression System: Baculovirus Insect Cells

CDK2 Protein, Human, Recombinant (His)

TMPY-04542

Species: Human

Expression System: Baculovirus Insect Cells

MOB1A Protein, Human, Recombinant (His)

TMPJ-01335

Species: Human

Expression System: E. coli

EFNB2 Protein, Mouse, Recombinant (hFc & His)

TMPJ-00224

Species: Mouse

Expression System: HEK293 Cells

PELI3 Protein, Human, Recombinant (His)

TMPH-01265

Species: Human

Expression System: E. coli

CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)

TMPY-04423

Species: Human

Expression System: Baculovirus Insect Cells

Cbl-c Protein, Human, Recombinant (His & GST)

TMPY-03510

Species: Human

Expression System: Baculovirus Insect Cells

ROR2 Protein, Human, Recombinant (His & Avi)

TMPK-00577

Species: Human

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (hFc)

TMPK-00579

Species: Human

Expression System: HEK293 Cells

SMAD2 Protein, Human, Recombinant (His & SUMO)

TMPH-01699

Species: Human

Expression System: E. coli

SORBS2 Protein, Human, Recombinant (His)

TMPH-02126

Species: Human

Expression System: E. coli

--------- More ---------

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L2200	Tyrosine Kinase Inhibitor Library	1016 compounds
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L3700	JAK-STAT Compound Library	252 compounds
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L8300	Chromatin Modification Compound Library	250 compounds
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L9410	Covalent Inhibitor Library	1920 compounds
	A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，acrylamide, ketocarbonyl，disulfide bond, etc.