571
120
1748
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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T17018 | TCPOBOP | BCL | |
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins. | |||
T11944 | Maritoclax | Marinopyrrole A | BCL |
Maritoclax (Marinopyrrole A) (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor, shows >8 fold selectivity than BCL-xl (IC50 > 80 μM),with an IC50 value of 10.1 μM. | |||
T14376 | AZD4320 | BCL | |
AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively. | |||
T5346 | S63845 | BCL | |
S63845 is a selective MCL-1 inhibitor(Kd: 0.19 nM) | |||
T14071 | A-385358 | BCL | |
A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively. | |||
T14561 | BI-3812 | BCL | |
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 nM). BI-3812 also has antitumor activity. | |||
T1980 | HA14-1 | BCL | |
HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM). | |||
T6650 | Sabutoclax | BI-97C1 | BCL |
Sabutoclax (BI-97C1)(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. | |||
T2453 | BAM7 | BCL | |
BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM). | |||
T5108 | ML311 | BCL | |
ML311 is a selective inhibitor of the Mcl-1/Bim interaction. | |||
T5408 | BI-3802 | BCL | |
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependen... | |||
T6749 | A-1331852 | BCL | |
A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases. | |||
T4089 | FX1 | Apoptosis , BCL | |
FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM). | |||
T2632 | A-1210477 | Apoptosis , BCL | |
A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM). | |||
T6281 | TW-37 | TW 37 | BCL |
TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM). | |||
T6034 | UMI-77 | UMI77,UMI 77 | BCL |
UMI-77, a specific Mcl-1 inhibitor (Ki: 490 nM), has selectivity over other members of Bcl-2 family. | |||
T8535 | GAK inhibitor 49 | Serine/threonin kinase | |
GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ). | |||
T2101 | Navitoclax | ABT-263 | BCL |
Navitoclax (ABT-263) is a Bcl-2 inhibitor that binds to Bcl-xL, Bcl-2, and Bcl-w proteins (Ki<1 nM) with potent and oral activity. Navitoclax has antitumor activity and induces apoptosis. | |||
T4296 | MTX-211 | MTX 211 | EGFR , PI3K |
MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases. | |||
T3940 | CID5721353 | BCL6 inhibitor | Apoptosis , BCL |
CID5721353 (BCL6 inhibitor) is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. | |||
T6778 | BDA-366 | BCL | |
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-ap... | |||
T14834 | BT2 | BCL | |
BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, l... | |||
T6748 | A-1155463 | A 1155463,A1155463 | BCL |
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM). | |||
T5210 | BAI1 | Apoptosis , BCL | |
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM). | |||
T12824L | S55746 | BLC201 | BCL |
S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM). | |||
T5104 | BTSA1 | Apoptosis , BCL | |
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. | |||
T8958 | PU-H54 | GPR | |
PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 subpocket in Grp94. | |||
T15771 | Lobaplatin | D-19466 | DNA Alkylation |
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a ... | |||
T2099 | ABT-737 | Mitophagy , BCL , Autophagy | |
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM). | |||
T7123 | AMG-47a | VEGFR , p38 MAPK , JAK , Src | |
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei... | |||
T12041 | MIM1 | Inhibitor of Mcl-1 | BCL |
MIM1 (Inhibitor of Mcl-1) is an myeloid cell factor 1 (Mcl-1) inhibitor. | |||
T12186 | Navitoclax-piperazine | ABT-263-piperazine | BCL , Ligands for Target Protein for PROTAC |
Navitoclax-piperazine (ABT-263-piperazine) is an inhibitor of B-cell lymphoma extra large (BCL-XL). | |||
T1816 | (Z)-JIB-04 | NSC 693627,Z-JIB-04 | Others |
(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04. | |||
T29856 | Aleplasinin | PAZ 417,PAZ417,PAZ-417 | PAI-1 |
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies... | |||
T6275 | Obatoclax Mesylate | Obatoclax,GX15-070 | BCL , Parasite , Autophagy |
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. | |||
T2119 | Venetoclax | GDC-0199,ABT 199,ABT-199,ABT199 | BCL , Autophagy |
Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces a... | |||
T6941 | PI-1840 | PI 1840 | PARP , Proteasome |
PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L). | |||
T39910 | Desmorpholinyl Navitoclax-NH-Me | Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me | BCL |
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2]. | |||
T1493 | BH3I-1 | BHI1 | BCL , E1/E2/E3 Enzyme |
BH3I-1 (BHI1) is a Bcl-2 antagonist. | |||
T2167 | Lutidinic acid | 2,4-Pyridinedicarboxylic acid,2,4-Dicarboxypyridine,2, 4-PDCA,2,4-PDCA | Histone Methyltransferase |
lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases. | |||
T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T16028 | IMB-XH1 | Mcl1-IN-2 | BCL , Antibacterial |
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor. | |||
T9945 | MNK8 | 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione | STAT |
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1]. | |||
T6396 | (R)-(-)-Gossypol acetic acid | (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101,AT101 acetate | BCL , Autophagy |
(R)-(-)-Gossypol acetic acid (AT101 acetate) , the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2. | |||
T8333 | Aurintricarboxylic acid | ATA,NSC-4056,NSC4056,NSC 4056 | Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase |
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. | |||
T9083 | TC11 | CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11 | BCL , Caspase , CDK |
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9. | |||
T1406 | Amantadine hydrochloride | 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride | Dopamine Receptor , Influenza Virus |
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease. | |||
T8473 | MLS000532223 | Rho , Ras | |
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM). | |||
T4344 | ALW-II-41-27 | Eph receptor tyrosine kinase inhibitor | Ephrin Receptor |
ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy. | |||
T13824 | PP58 | FGFR , p38 MAPK , TNF , PDGFR , Src | |
PP58 is an inhibitor of PDGFR, FGFR and Src family. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3824 | Jaceosidin | Apoptosis , BCL , COX , UGT | |
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway... | |||
TN6798 | Progoitrin | Others | |
Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p... | |||
TN1406 | Dihydrokaempferol | Aromadendrin | Apoptosis , BCL |
Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory, antioxidant, and anti-diabetic properties, it exhibits anti-inflammatory ... | |||
T8213 | Isolinderalactone | NOS , STAT | |
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM. | |||
T6518 | Gossypol | Pogosin,BL 193,NSC 56817 | BCL , Dehydrogenase |
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. | |||
T6S0052 | Chelerythrine | Toddalin,Broussonpapyrine,Cheleritrine | Apoptosis , BCL , PKC , Autophagy |
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera... | |||
T3419 | Chelerythrine chloride | Apoptosis , BCL , PKC , Autophagy | |
Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. | |||
T5S2358 | Dehydrocorydaline | Dehydrocorydalin,13-Methylpalmatine | BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy |
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz... | |||
T7979 | 2-Hydroxychalcone | 2-(2-Hydroxybenzal)Acetophenone | Apoptosis , BCL , Others , NF-κB |
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells. | |||
T2S2362 | Dehydrocorydaline nitrate | BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy | |
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a... | |||
T10990 | Dehydrocorydaline chloride | 13-Methylpalmatine chloride | BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy |
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK. | |||
T6185 | Gambogic Acid | Beta-Guttiferrin,Guttatic Acid,Guttic Acid | BCL , Autophagy |
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 ... | |||
T5679 | (E)-Ferulic acid | trans-Ferulic acid,(E)-Coniferic acid | BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite |
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr... | |||
T3344 | Ciwujianoside B | yemuoside YM,acanthopanax senticosides B,Ciwujianoside-B | BCL , Others |
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition. | |||
T2730 | Gossypol (acetic acid) | (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid | BCL |
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID. | |||
T2163 | Dihydrocapsaicin | CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide | Others , TRP/TRPV Channel |
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an... | |||
T2851 | Daphnetin | 7,8-Dihydroxycoumarin,Daphnetol | EGFR , PKA , PKC , Parasite , Autophagy |
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-... | |||
T4085 | Paris saponin VII | Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII | Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy |
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation. | |||
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. | |||
T4024 | Norharmane | 2-Azacarbazole,2,9-Diazafluorene,β-Carboline | DNA , Endogenous Metabolite , Monoamine Oxidase |
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family. | |||
TN1145 | Isofebrifugine | Parasite | |
Isofebrifugine is an alkaloid from the plant Changshan of the Saxifrage family with antimalarial and anti-infectious activity. | |||
TN7208 | 2-Methyladenosine | 2-methyl adenosine | Others |
2-Methyladenosine (2-methyl adenosine) is a marine derived natural products found in Family Tethyidae. | |||
TN7194 | AC-PHE-OME | Methyl N-acetyl-L-phenylalaninate,N-Acetyl-L-phenylalanine methyl ester,N-acetyl phenylalanine methyl ester | Others |
AC-PHE-OME (Methyl N-acetyl-L-phenylalaninate) is a marine derived natural products found in Family Jaspidae. | |||
T19503 | Papain | Others , Cysteine Protease | |
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries. | |||
TN1333 | 7-O-Methylbiochanin A | 4',7-Dimethoxy-5-hydroxyisoflavone | |
7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative that can be isolated from the roots of Lotus polyphyllos and other plants of the water lily family. | |||
TMS2181 | Trans-Zeatin | (E)-Zeatin | ERK , MEK , Endogenous Metabolite |
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing. | |||
TMO2790 | 1-Naphthaleneacetic acid | Transplantone,1-Naphthylacetic acid,α-Naphthaleneacetic acid,Phyomone | Phospholipase |
1-Naphthaleneacetic acid (Transplantone) , is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural produ... | |||
T3323 | Ursonic Acid | CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966 | Apoptosis , HIV Protease , Endogenous Metabolite |
Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor. | |||
TN2156 | Rhombifoline | Antioxidant | |
Rhombifoline is a family of alkaloids isolated from the leaf stems of Anagyrus foetida and Genista tenera. | |||
T25192 | Butyrolactone I | Olomoucin | CDK |
Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines. | |||
T3S2390 | Caftaric acid | trans-Caftaric acid | Others |
Caftaric acid (trans-Caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by Src family kinases. | |||
T3908 | 10-Gingerol | Apoptosis | |
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK). | |||
T5763 | Sedanolide | Others , Autophagy | |
Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery. | |||
T5986 | 3-Hydroxypicolinic acid | Picolinic acid, 3-hydroxy- (6CI,7CI,8CI),2-Carboxy-3-hydroxypyridine | Endogenous Metabolite |
3-Hydroxypicolinic acid (Picolinic acid, 3-hydroxy- (6CI,7CI,8CI)), a picolinic acid derivative, belongs to the pyridine family. | |||
T6817 | Deguelin | (-)-Deguelin,(-)-cis-Deguelin | Apoptosis , Akt , PI3K , Autophagy |
Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family. | |||
T4010 | Juglone | 5-Hydroxy-1,4-naphthoquinone,Regianin | DNA/RNA Synthesis , Antibacterial |
Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin fam... | |||
T13854 | Quininic acid | NMDAR | |
Quinic acid is an organic acid extracted from the bark of Eucalyptus, Cinchona and other plants in the Asteraceae family. | |||
T20003 | Acridone | Antibacterial , ABC | |
Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level. | |||
T22218 | 2'-Deoxyguanosine | Deoxyguanosine,Guanine deoxyriboside | Endogenous Metabolite |
2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol... | |||
Fr16741 | Oxindole | Indolin-2-one | Others , HIV Protease |
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ... | |||
T6361 | Indole-3-butyric acid | 3-Indolebutyric acid,IBA,Hormodin | Others , Endogenous Metabolite |
Indole-3-butyric acid (IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products. | |||
T2721 | Digitonin | Others | |
Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of... | |||
T13857 | (R,S)-Anatabine | Others | |
(R,S)-Anatabine is a minor tobacco alkaloid found in the Solanaceae family of plants,and can be used as a specific marker for the detection of tobacco use. | |||
T1188 | Mizoribine | Bredinin,NSC 289637,HE 69 | HCV Protease , SARS-CoV , Tyrosinase |
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. | |||
T5595 | Tropine | 3alpha-Tropanol,Pseudotropine | Others |
Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive alkaloids. | |||
T67922 | Lepidiline C | Others | |
Lepidiline C is a novel imidazoles alkaloids extracted from the root of Lepidium meenii Walpers of the brassaceae family. It has shown cytotoxic activity against HL-60 cells (IC50:27.7 μM). | |||
TN6742 | β-Damascone | Damascone | Others |
β-Damascone are a series of closely related chemical compounds that are components of a variety of essential oils. The damascones belong to a family of chemicals known as rose ketones, which also includes damascenones an... | |||
T6S1418 | Praeruptorin C | Antioxidant , Calcium Channel | |
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ... | |||
T0879 | Niacin | Vitamin B3,Nicotinic acid | Endogenous Metabolite , Autophagy |
Niacin (Nicotinic acid) is a water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, w... | |||
T2801 | Aristolochic acid A | TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid | Others , NF-κB |
Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01458 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.8 kDa and the accession number is O60609-1. | |||
TMPY-02938 | REG4 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
REG4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q68AX7. | |||
TMPY-02525 | RGMA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th... | |||
TMPY-00484 | Cerberus 1/CER1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Cerberus 1/CER1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is AAH69371.1. | |||
TMPY-02785 | Tetranectin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Tetranectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is P43025. | |||
TMPY-01483 | SLAMF7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q9NQ25-1. | |||
TMPY-00586 | CLEC-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1. | |||
TMPY-02971 | CLEC10A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2. | |||
TMPY-02580 | Histone H1 Protein, Human, Recombinant (His) | Human | E. coli |
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "... | |||
TMPJ-01210 | IL-33 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. | |||
TMPY-02062 | SULT1A1 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid... | |||
TMPY-03419 | SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST) | Human,Mouse,Rat | Baculovirus Insect Cells |
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is... | |||
TMPY-01032 | CD299 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD299 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H2X3-1. | |||
TMPY-03990 | Profilin 4 Protein, Human, Recombinant (His) | Human | E. coli |
PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilamen... | |||
TMPY-02092 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41~45 kDa and the accession number is EAW96132.1. | |||
TMPY-03684 | REG1A Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
REG1A Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.3 kDa and the accession number is G8F4F8. | |||
TMPY-03639 | REG1A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
REG1A Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 7.10 kDa and the accession number is G8F4F8. | |||
TMPY-03714 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q62997. | |||
TMPY-01994 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q62997-1. | |||
TMPJ-00608 | SLAMF9 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse SLAM family member 9(Slamf9) is a single-pass type I membrane protein. The SLAMF9 gene encodes a member of the signaling lymphocytic activation molecule family. The encoded protein is a cell surface molecule that c... | |||
TMPY-04203 | RAB1B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... | |||
TMPY-03586 | HEPACAM2 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
HEPACAM2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.3 kDa and the accession number is B5DEN8. | |||
TMPY-02903 | COLEC12 Protein, Rat, Recombinant (His) | Rat | Baculovirus Insect Cells |
COLEC12 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.4 kDa and the accession number is Q4V885. | |||
TMPY-04686 | SHISA3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
SHISA3(high)CLL are characterized by a restrained activation of Wnt signaling and sensibility to lenalidomide-induced apoptosis. SHISA3 promoter hypermethylation might increase the risk of LSCC through regulation of gene... | |||
TMPY-03709 | GFR Alpha-1/GFRA1 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
GFR Alpha-1/GFRA1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A8C0TV81. | |||
TMPY-03774 | COLEC12 Protein, Rhesus, Recombinant (His) | Rhesus | Baculovirus Insect Cells |
COLEC12 Protein, Rhesus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.3 kDa and the accession number is F6RUR9. | |||
TMPY-03068 | HEPACAM2 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
HEPACAM2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.7 kDa and the accession number is B5DEN8. | |||
TMPY-04074 | CNKSR3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
CNKSR3 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 66.7 kDa and the accession number is Q6P9H4. | |||
TMPY-01088 | GFR Alpha-1/GFRA1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
GFR Alpha-1/GFRA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.3 kDa and the accession number is P97785-2. | |||
TMPY-03997 | COLEC11 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
COLEC11 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 27.70 kDa and the accession number is Q3SXB8-1. | |||
TMPY-01391 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.3 kDa and the accession number is O60609-1. | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2. | |||
TMPY-04112 | RAB31 Protein, Human, Recombinant (His) | Human | E. coli |
RAB31 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q13636. | |||
TMPY-04152 | RAB7A Protein, Rat, Recombinant (His) | Rat | E. coli |
RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is import... | |||
TMPY-03132 | REG4 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
REG4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q68AX7. | |||
TMPY-03092 | REG1A Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
REG1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.8 kDa and the accession number is P10758. | |||
TMPY-02442 | ELK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
E twenty-six (ETS)-like transcription factor 1, also known as Elk1 or Member of ETS oncogene family (ELK1), is a member of the ETS oncogene superfamily which is characterized by a common protein domain that regulates DNA... | |||
TMPY-01090 | REG3A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
REG3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is O09037. | |||
TMPY-03732 | CLM-9 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CLM-9 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.5 kDa and the accession number is A6HJG1. | |||
TMPY-01440 | GFR Alpha-2/GFRA2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
GFR Alpha-2/GFRA2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.5 kDa and the accession number is O08842-1. | |||
TMPY-03134 | REG3A Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
REG3A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.9 kDa and the accession number is BAA04904.1. | |||
TMPY-06226 | SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like ... | |||
TMPY-03133 | REG3A Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
REG3A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is BAA04904.1. | |||
TMPY-04022 | BOLA1 Protein, Human, Recombinant (His) | Human | E. coli |
BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA... | |||
TMPY-02536 | GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.2 kDa and the accession number is O35118. | |||
TMPY-01831 | SLAMF8 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a... | |||
TMPY-03894 | GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is O35118. | |||
TMPY-00490 | RAB6A Protein, Human, Recombinant (His) | Human | E. coli |
Rab6 is one of the most conserved Rab GTPaes throughout evolution and the most abundant Rab protein associated with the Golgi complex. The two ubiquitous Rab isoforms, Rab6A and Rab6A', that are generated by alternative ... | |||
TMPY-04311 | RAB11B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization. | |||
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