|
T14871 |
Carboxyamidotriazole Orotate
|
L-651582 Orotate,CAI Orotate |
Calcium Channel
|
|
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o... |
|
T30687 |
CAI-1
|
Cholerae autoinducer 1,Cholerae autoinducer-1 |
|
|
CAI-1 is a vibrio cholerae quorum-sensing autoinducer. |
|
T14872 |
Carboxyamidotriazole
|
CAI,L-651582 |
Calcium Channel
|
|
Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects. |
|
T2017 |
U-104
|
NSC-213841,MST-104 |
Carbonic Anhydrase
|
|
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM). |
|
T10679 |
Carcainium chloride
|
QX 572,Carcainium (chloride),Carcainiumchloride,RSD 931 |
Others
|
|
Carcainium chloride (Carcainium (chloride)) is a derivative of Lidocaine and possesses an antitussive effect. |
|
T21483 |
Tricaine methanesulfonate
|
MS-222 |
Others
|
|
Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures. |
|
T0386 |
Ropivacaine hydrochloride
|
Ropivacaine monohydrochloride |
Potassium Channel
,
Sodium Channel
|
|
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. |
|
T23969 |
DCAI
|
|
Others
|
|
DCAI is an inhibitor of nucleotide exchange and nucleotide release acting by binding to the pocket adjacent to the Ras-SOS interface. |
|
T0946 |
Mepivacaine hydrochloride
|
Mepivacaine HCl |
Sodium Channel
|
|
Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties. |
|
T0364 |
Dibucaine
|
Cinchocaine |
CaMK
,
Sodium Channel
,
AChR
|
|
Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia. |
|
T13177L |
Tocainide
|
|
Sodium Channel
|
|
Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus. |
|
T1144 |
Lidocaine hydrochloride
|
Lidocaine HCL,Lignocaine hydrochloride,Xyloneural,Lidothesin |
Apoptosis
,
ERK
,
NF-κB
,
MEK
,
Sodium Channel
|
|
Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its ... |
|
T7219 |
Flecainide acetate
|
Flecainide (acetate),R-818 |
Sodium Channel
|
|
Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart). |
|
T0796 |
Prilocaine hydrochloride
|
Prilocaine HCl,Propitocaine hydrochloride,Xylonest |
ATPase
,
Sodium Channel
|
|
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. |
|
T1697 |
Debutylbupivacaine
|
|
Others
|
|
Debutylbupivacaine is the intermediate of ropivacaine hydrochloride and bupivacaine. |
|
T6782L |
Benzocaine xHCl(94-09-7(free base))
|
|
Sodium Channel
|
|
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV). |
|
T0386L |
Ropivacaine
|
LEA-103 HCl |
Potassium Channel
,
Sodium Channel
|
|
Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group. |
|
T80663 |
HCAI/II/IV-IN-28
|
WAY-638358 |
Carbonic Anhydrase
|
|
hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity. |
|
T9397 |
Parethoxycaine hydrochloride
|
2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride,Diethoxin |
Others
|
|
Parethoxycaine hydrochloride (2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride) is an anesthetic[1]. |
|
T22361 |
Mepivacaine
|
Carbocaine |
Sodium Channel
|
|
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve ce... |
|
T4539 |
Nicainoprol
|
RU-42924 |
Sodium Channel
|
|
Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent. |
|
T17115 |
Tolycaine
|
|
|
|
Tolycaine is a compound of local anesthetic. |
|
T31716 |
Etidocaine Hydrochloride
|
W-19053,Duranest,W19053,W 19053 |
Sodium Channel
|
|
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel. |
|
T68143 |
Solpecainol
|
|
Sodium Channel
|
|
solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases. |
|
T0924 |
Benzocaine
|
|
Others
,
MRP
,
Sodium Channel
|
|
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
|
T7811 |
Pilsicainide HCl
|
SUN 1165 |
Sodium Channel
|
|
Pilsicainide HCl (SUN 1165) is a pure sodium channel blocker |
|
T68165 |
Trapencaine
|
|
|
|
Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes. |
|
T6566 |
Levobupivacaine hydrochloride
|
Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride |
Sodium Channel
|
|
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic... |
|
T6443 |
Chloroprocaine hydrochloride
|
Chloroprocaine HCl |
ATPase
,
Others
|
|
Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures. |
|
T4553 |
Procaine penicillin G
|
Duphapen,Hydracillin,Hostacillin |
Antibiotic
|
|
Procaine penicillin G (Duphapen) (procaine benzylpenicillin) is an antibiotic useful for the treatment of a number of bacterial infections. Specifically, it is used for syphilis, anthrax, mouth infections, pneumonia, dip... |
|
T0030 |
Bupivacaine hydrochloride
|
Vivacaine,Bupivacaine HCl |
Sodium Channel
|
|
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol... |
|
T0018 |
Procainamide hydrochloride
|
Procapan,Procainamide HCl,Pronestyl,Procanbid |
DNA Methyltransferase
,
Sodium Channel
,
AChR
,
Autophagy
|
|
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to... |
|
T0802 |
Procaine hydrochloride
|
Novocaine HCl,Procaine HCl |
Histone Demethylase
,
5-HT Receptor
,
DNA/RNA Synthesis
,
Sodium Channel
,
NMDAR
,
AChR
|
|
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... |
|
T6645 |
Ropivacaine hydrochloride monohydrate
|
Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl |
Potassium Channel
,
Sodium Channel
|
|
Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly. |
|
T6953 |
Prilocaine
|
Citanest,Propitocaine,NSC 40027 |
ATPase
,
Sodium Channel
|
|
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures. |
|
T1144L |
Lidocaine Hydrochloride hydrate
|
|
EGFR
,
Sodium Channel
|
|
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property. |
|
T7118 |
Dimethocaine
|
Larocaine |
Others
,
Dopamine Receptor
|
|
Dimethocaine (Larocaine) is a local anesthetic which also effects on the central nervous system acting as dopamine-reuptake-inhibitor. |
|
T0468 |
Lidocaine
|
Lignocaine,Alphacaine,Xylocaine |
Apoptosis
,
ERK
,
NF-κB
,
MEK
,
Sodium Channel
,
Histamine Receptor
|
|
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammat... |
|
T0460 |
Pramocaine hydrochloride
|
Pramoxine hydrochloride,Pramoxine HCl |
Sodium Channel
|
|
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic. |
|
T0030L |
Bupivacaine
|
AH 250,AH-250,AH250,Bupivacaina,Exparel,Anekain |
NMDAR
|
|
Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the resea... |
|
T0378 |
Oxybuprocaine hydrochloride
|
Risedronic Acid,Oxybuprocaine HCl |
Sodium Channel
|
|
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology. |
|
T15653 |
Ketocaine
|
Rec 7-0518 |
Others
|
|
Ketocaine（Rec 7-0518） is a local anesthetic commonly used in animal experiments with potential antitumor activity for pain relief. |
|
T67960 |
Recainam
|
|
|
|
Recainam is a novel, orally available compound with potent class I antiarrhythmic activity. |
|
T0222 |
Proparacaine hydrochloride
|
Proparacaine HCl,Proxymetacaine Hydrochloride |
Apoptosis
,
Sodium Channel
|
|
Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride (Proparacaine HCl) stabilizes the neuronal membrane by bindi... |
|
T35009 |
Vadocaine
|
Vadocaina,Vadocainum |
Others
|
|
Vadocaine (Vadocaina) is a novel analgesic compound for local anaesthesia and can be used to study the central nervous system and cardiovascular system. |
|
T0364L |
Dibucaine hydrochloride
|
Cinchocaine HCl,Dibucaine HCl,Cinchocaine hydrochloride |
Sodium Channel
,
AChR
|
|
Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia. |
|
T14034 |
3CAI
|
|
Akt
|
|
|
|
T60322 |
Procainamide
|
Biocoryl,Novocainamide |
DNA Methyltransferase
|
|
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmia... |
|
T31716L |
Etidocaine
|
|
Others
|
|
Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties. |
|
T11099 |
Droxicainide
|
|
Others
|
|
Droxicainide is an antiarrhythmic agent. |
