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Search Results for " D 13 "

23

阻害剤

7

天然化合物

6

リコンビナントタンパク質

1

同位体標識化合物

カタログ番号 製品名 別名 ターゲット
T37985 D-Fructose-6-phosphate (sodium salt hydrate) D-Fructose-6-phosphate (sodium salt hydrate) (643-13-0 free base)
D-Fructose-6-phosphate (sodium salt hydrate) is a sugar intermediate in the glycolytic pathway produced by the isomerization of glucose 6-phosphate by glucose phosphate isomerase, and is used in cancer research.
T36054 D13 Others
D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infect...
T9310 MTOR inhibitor 13 PI3K , mTOR
mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.
T10944 D13-9001 Others
The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-Op...
T24968 13-Deoxycarminomycin R20X,R-20X,Antibiotic D 788-11,R 20X Others
13-Deoxycarminomycin is an antitumor antibiotic.
T14589 Biotin-PEG3-acid Others , PROTAC Linker
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophil...
T3407 Rapastinel GLYX-13,Thr-Pro-Pro-Thr-NH2,TPPT-amide NMDAR , iGluR
Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T2664 Timapiprant OC000459 GPR , Prostaglandin Receptor
Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).
T14943 CGP60474 VEGFR , CDK , PKC
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.
T31190 Dafphedyn Others
Dafphedyn, [D-Ala2, (F5) Phe4]-dynorphin 1-13-NH2 (DAFPHEDYN) is an effective analog of strong endorphin 1-13 and produces diuretic and deep analgesia when administered intravenously in rats.
T38695 2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose Others
2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose (compound 13) functions as a potent hepatic glycosaminoglycan biosynthesis inhibitor.
T125682 Schisanchinin D Others
Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.
TP1023 NT 13 TPPT
NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.
T17099 Timapiprant sodium OC000459 sodium Others
Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h...
T37565 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide (d18:1/6:0) Others
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlik...
T37056 D-erythro-MAPP Others
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon...
T81451 PKCd (8-17)
PKCd (8-17) is a bioactive peptide originating from the V1 domain of protein kinase C (PKC)d. It impedes phorbol 12-myristate 13-acetate (PMA)-stimulated PKCd translocation and activation, which mitigates ischemic injury...
T36396 D-Homoserine lactone Others
D-homoserine lactone is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki= 11 mM for the rabbit enzyme).1 1.Wang, E.A., Kallen, R., and Walsh, C.Mechanism-based inactivat...
T36281 VH 032 amide-alkylC5-amine VH 032 amide-alkylC5-amine Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part ...
T36917 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) Others
Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helt...
T37874 Feglymycin
Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replica...
T37860 T 26c disodium salt Others
Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable. Nar...
T36176 AMK (hydrochloride) Others
AMK is an active metabolite of the neurohormone melatonin .1,2,3,4It is formed from melatoninviathe metabolic intermediate AFMK that is then deformylated by catalase or formamidase.5,6AMK scavenges singlet oxygenin vitro...
カタログ番号 製品名 別名 ターゲット
TN6271 11β,13-Dihydrotaraxinic acid β-D-glucopyranosyl ester
11β,13-Dihydrotaraxinic acid β-D-glucopyranosyl ester is a natural product for research related to life sciences. The catalog number is TN6271 and the CAS number is 75911-16-9.
TN6498 Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester)
Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester) is a natural product for research related to life sciences. The ...
TN2661 19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide Others
19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a natural product for research related to life sciences. The catalog number is TN2661 and the CAS number is 919120-78-8.
T3889 Platycodin D Prostaglandin Receptor , AMPK
Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...
TN6432 Bergaptol O-β-D-glucopyranoside Bergaptol-beta-glucopyranoside
Bergaptol O-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN6432 and the CAS number is 131623-13-7.
T75567 Cabenoside D Others
Cabenoside D (compound 8), a triterpenoid glycoside derived from the methanol extract of lichen root, exhibits anti-inflammatory activity. It effectively inhibits inflammation and the activation of early Epstein-Barr vir...
T37272 9(S),12(S),13(S)-TriHOME Others
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPK-00075 IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPK-00074 IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPH-01632 MRC1 Protein, Human, Recombinant (His) Human E. coli
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbia...
TMPY-03391 ESD Protein, Human, Recombinant (His) Human E. coli
Esterase D, also known as ESD, is a serine hydrolase that belongs to the esterase D family. Esterase D is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of ...
TMPK-01391 Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) Human HEK293 Cells
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...
TMPK-01373 Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) Human HEK293 Cells
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...

Isotope Products

カタログ番号 製品名 別名 ターゲット
T13432 β-Apo-13-carotenone D3 D'Orenone D3 Others
β-Apo-13-carotenone D3 is the deuterium labeled β-Apo-13-carotenone. β-Apo-13-carotenone is an antagonist of RXRα.