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Search Results for " EV71 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T18928	Brilliant Black BN	E 151	Others , Virus Protease
	Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A.		Others , Virus Protease
T16809	Rupintrivir	AG-7088,AG7088,Rupintrivirvr	Virus Protease , Antiviral
	Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be u...		Virus Protease , Antiviral
T61334	DMA-135 hydrochloride	DMA-135 HCl	Virus Protease
	DMA-135 hydrochloride (DMA-135 HCl) Antivirally active compounds that target RNA and inhibit enterovirus type 71 (EV71) IRES-dependent translation and replication.DMA-135 hydrochloride can be used in the study of enterov...		Virus Protease
T13284	Vapendavir diphosphate	BTA798 diphosphate	Others
	Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).		Others
T13284L	Vapendavir	BTA798	Others
	Vapendavir is a potent enteroviral capsid binder. Vapendavir has an effective antiviral activity for enterovirus 71 replication (EC50: 0.5-1.4 μM in different EV71 strains).		Others
T63563	AN-12-H5
	AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.
T11329	FT895		HDAC , Antifungal
			HDAC , Antifungal
T72562	Antiviral agent 23
	Antiviral Agent 23, an effective inhibitor of enterovirus 71 (EV71) with an EC50 value of 94 nM, also exhibits potent suppression of METTL3/METTL14 activity. This compound is employed in the research of infections.
T78455	Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
	Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye that serves as an effective quencher for quantum dots (QDs) fluorescence and as a capture probe for the virus antigen EV71. Additionally, it can be utilize...
T27126	DC07090 Dihydrochloride
	DC07090 Dihydrochloride is a potent inhibitor of human enterovirus 71 3C protease.

Compounds

Brilliant Black BN

T18928

Synonym: E 151

Target: Others, Virus Protease

Rupintrivir

T16809

Synonym: AG-7088,AG7088,Rupintrivirvr

Target: Virus Protease, Antiviral

DMA-135 hydrochloride

T61334

Synonym: DMA-135 HCl

Target: Virus Protease

Vapendavir diphosphate

T13284

Synonym: BTA798 diphosphate

Target: HDAC, Antifungal

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2

T78455

Synonym:

Target:

DC07090 Dihydrochloride

T27126

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T8205	Norwogonin	5,7,8-Trihydroxyflavone	Virus Protease
	Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).		Virus Protease
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T2843	Aloe emodin	NSC 38628,3-Hydroxymethylchrysazine,Rhabarberone,Aloe-emodin	Autophagy , HSV
	Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV （IC50=1 μg/mL） and EV71（IC50=0.33 μg/mL ）.		Autophagy , HSV
T5779	MOSLOFLAVONE		IL Receptor , Virus Protease , TNF , Antibacterial
	MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.		IL Receptor , Virus Protease , TNF , Antibacterial
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
TN1668	Ganoderic acid Y		Antifection
	Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.		Antifection
TN4748	Penduletin		VEGFR , COX , Prostaglandin Receptor , Antifection
	Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong activity in vitro against EV71 with low cyto...		VEGFR , COX , Prostaglandin Receptor , Antifection

天然物製品

Norwogonin

T8205

Synonym: 5,7,8-Trihydroxyflavone

Target: Virus Protease

Corydaline

T5S2360

Synonym: Corydalin,(+)-Corydaline

Target: P450, Virus Protease, Opioid Receptor, AChE

Aloe emodin

T2843

Synonym: NSC 38628,3-Hydroxymethylchrysazine,Rhabarberone,Aloe-emodin

Target: Autophagy, HSV

MOSLOFLAVONE

T5779

Synonym:

Target: IL Receptor, Virus Protease, TNF, Antibacterial

Corilagin

T3795

Synonym:

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Target: VEGFR, COX, Prostaglandin Receptor, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00299	LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far e...
TMPJ-00298	CD36 Protein, Human, Recombinant (aa 27-432, His)	Human	HEK293 Cells
	Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlie...
TMPY-02060	Human Enterovirus 71 VP0 Protein (His & GST)	EV71	Baculovirus Insect Cells
	Human enterovirus 71 genome polyprotein is a member of the picornaviruses polyprotein family. It contains two peptidase C3 domains, one RdRp catalytic domain, one SF3 helicase domain. Genome polyprotein is cleaved into t...
TMPH-02841	Prohibitin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul...

LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)

TMPJ-00299

Species: Mouse

Expression System: HEK293 Cells

CD36 Protein, Human, Recombinant (aa 27-432, His)

TMPJ-00298

Species: Human

Expression System: HEK293 Cells

Human Enterovirus 71 VP0 Protein (His & GST)

TMPY-02060

Species: EV71

Expression System: Baculovirus Insect Cells

Prohibitin Protein, Mouse, Recombinant (His)

TMPH-02841

Species: Mouse

Expression System: E. coli