検索結果

Search Results for " Emb "

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

同位体標識化合物

カタログ番号	製品名	別名	ターゲット
TMAZ-0077	Anti-EMB Monoclonal Antibody

TMAZ-0077A6	Anti-EMB Monoclonal Antibody-AF647

TMAZ-0077A5	Anti-EMB Monoclonal Antibody-AF555

TMAZ-0077A4	Anti-EMB Monoclonal Antibody-AF488

TMAZ-0077A	Anti-EMB Monoclonal Antibody-APC

TMAZ-0077P	Anti-EMB Monoclonal Antibody-PE

TMAZ-0077B	Anti-EMB Monoclonal Antibody-Biotin

T27112	Cytembena		DNA/RNA Synthesis
	Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.		DNA/RNA Synthesis
T28750	Sembragiline	RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302	MAO
	Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).		MAO
TP1286	Carcinoembryonic Antigen CEA		Others
	Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)		Others
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
T3071	Olverembatinib	GZD 824	Bcr-Abl
	Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).		Bcr-Abl
T60093	CHEMBL1380345	N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)	Antibacterial
	CHEMBL1380345 exhibits antibacterial activity against Staphylococcus aureus, Bacillus cereus, and Escherichia coli with pMIC values of 3.64, 3.56, and 3.70, respectively.		Antibacterial
T74178	Glembatumumab vedotin	CR011-vcMMAE,CR 011 ADC,CDX-011	Microtubule Associated
	Glembatumumab vedotin (CDX-011) is an antibody-activated small molecule coupling, Glembatumumab vedotin has potent anticancer effects and can be used in the study of triple negative breast cancer (TNBC).		Microtubule Associated
T2429	Olverembatinib dimesylate	GZD824 Dimesylate,HQP1351	Bcr-Abl
	Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).		Bcr-Abl
T8598	CHEMBL241987	2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE	Adenosine Receptor
	CHEMBL241987 targets the Adenosine receptor A3 (human)		Adenosine Receptor
T9908	Pembrolizumab		PD-1/PD-L1
	Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ...		PD-1/PD-L1
T67988	Embeconazole	R 120758,CS 758	Antifungal
	Embeconazole (R 120758) is a triazole antifungal agent.Embeconazole has strong in vitro activity against clinically important fungi such as Candida, Aspergillus and Cryptococcus neoformans.		Antifungal
T77439	Glembatumumab		Others
	Glembatumumab is a fully human IgG2 monoclonal antibody targeting the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma.Glembatumumab is a naked antibody to Glembatumumab vedotin and ...		Others
TP2417	Tidembersat		Others
	Tidembersat is a small molecule compound used to treat and/or prevent degenerative diseases such as Huntington's chorea, schizophrenia, neurological.		Others
T60092	CHEMBL1276927	N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide	Antibacterial , Parasite
	CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and Leishmania donovani.		Antibacterial , Parasite
T70261	Amitriptyline Embonate		Others
	Amitriptyline Embonate is an inhibitor of the re-uptake of norepinephrine and serotonin, thereby inhibiting N-methyl-D-aspartate (NMDA) receptors.		Others
T124967	D7-Mesembrenone		Others
	D7-Mesembrenone is a useful organic compound for research related to life sciences. The catalog number is T124967 and the CAS number is 35714-44-4.		Others
T124052	Calophymembranside B		Others
	Calophymembranside B is a useful organic compound for research related to life sciences. The catalog number is T124052 and the CAS number is 869285-60-9.		Others
T31373	Dembrexine HCl	Dembroxol	Others
	Dembrexine is a bioactive agent.		Others
T11180	Embramine		Others
	Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.		Others
T80209	Human membrane-bound PD-L1 polypeptide		PD-1/PD-L1
	Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].		PD-1/PD-L1
T81824	Membrane-Permeable Sequence, MPS
	Membrane-Permeable Sequence (MPS) is a cell-penetrating peptide (CPP) utilized in the investigation of membrane crossing mechanisms [1].
TP2198	Platelet Membrane Glycoprotein IIB Peptide (296-306)		Others
	GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane doma...		Others
T70054	Novembichin		Others
	Novembichin is a nitrogen mustard agent that crosslinks with DNA, causing inhibition of DNA synthesis.		Others
T131462	Embelin Dimethyl ether		Others
	Embelin Dimethyl ether is a useful organic compound for research related to life sciences and the catalog number is T131462.		Others
T71902	CHEMBL94431		Others
	CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase.		Others
T68384	SCHEMBL12616233		Others
	SCHEMBL12616233 is a novel inhibitor of SARS-CoV-2 main protease (MPro).		Others
T82476	Embramine hydrochloride		Others
	Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].		Others
T131083	Cembratetraene-16,2:19,6-diolide		Others
	Cembratetraene-16,2:19,6-diolide is a useful organic compound for research related to life sciences and the catalog number is T131083.		Others
T124625	α-Cembrenediol		Others
	α-Cembrenediol is a useful organic compound for research related to life sciences and the catalog number is T124625.		Others
T28749	SEMBL		Others
	SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.		Others
T69405	Metformin embonate		Others
	Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.		Others
T31619	Embusartan	UNII-4MY73645XA,Bay 10-6734	Others
	Embusartan (BAY 10-6734) is a potent, orally active angiotensin II receptor antagonist used as an antihypertensive agent.		Others
T76916	Bafisontamab
	Bafisontamab (EMB-01) is a bispecific antibody that targets EGFR and cMET, displaying antitumor activity [1].
T37880	OPC-167832		Others
	OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...		Others

Compounds

Anti-EMB Monoclonal Antibody

TMAZ-0077

Synonym:

Target:

Anti-EMB Monoclonal Antibody-AF647

TMAZ-0077A6

Synonym:

Target:

Anti-EMB Monoclonal Antibody-AF555

TMAZ-0077A5

Synonym:

Target:

Anti-EMB Monoclonal Antibody-AF488

TMAZ-0077A4

Synonym:

Target:

Anti-EMB Monoclonal Antibody-APC

TMAZ-0077A

Synonym:

Target:

Anti-EMB Monoclonal Antibody-PE

TMAZ-0077P

Synonym:

Target:

Anti-EMB Monoclonal Antibody-Biotin

Target: DNA/RNA Synthesis

Sembragiline

T28750

Synonym: RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302

Target: MAO

Carcinoembryonic Antigen CEA

Target: TRP/TRPV Channel

Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)

Target: Antibacterial

Glembatumumab vedotin

T74178

Synonym: CR011-vcMMAE,CR 011 ADC,CDX-011

Target: Microtubule Associated

Olverembatinib dimesylate

T2429

Synonym: GZD824 Dimesylate,HQP1351

Target: Bcr-Abl

CHEMBL241987

T8598

Synonym: 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE

Target: Adenosine Receptor

Synonym: R 120758,CS 758

Synonym: N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide

Target: Antibacterial, Parasite

Amitriptyline Embonate

Human membrane-bound PD-L1 polypeptide

T80209

Synonym:

Target: PD-1/PD-L1

Membrane-Permeable Sequence, MPS

T81824

Synonym:

Target:

Platelet Membrane Glycoprotein IIB Peptide (296-306)

Embelin Dimethyl ether

Embramine hydrochloride

T82476

Synonym:

Target: Others

Cembratetraene-16,2:19,6-diolide

Synonym: UNII-4MY73645XA,Bay 10-6734

カタログ番号	製品名	別名	ターゲット
T0810	Ethambutol dihydrochloride	Ethambutol 2HCl,Emb dihydrochloride,CL40881	Antibacterial , Antibiotic , Antifungal
	Ethambutol dihydrochloride (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.		Antibacterial , Antibiotic , Antifungal
T13514	5-MethoxyPinocembroside		Others
	5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera.		Others
T2992	Pinocembrin	5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone	NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
	Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.		NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
T5710	Pinocembrin-7-O-β-D-glucopyranoside	Pinocembrin 7-O-beta-D-glucoside	Others
	Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) is a natual product isolated from Penthorum chinense Pursh.		Others
TN2078	Pinocembrin chalcone	2',4',6'-Trihydroxychalcone,Pinocembrinchalcone	Calcium Channel , Tyrosinase , Antibacterial , Antifection
			Calcium Channel , Tyrosinase , Antibacterial , Antifection
TN2077	(+/-)-Pinocembrin	NSC 43318,(±)-5,7-Dihydroxyflavanone	GPR , Others
	(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.		GPR , Others
T6485	Embelin	NSC 91874,Emberine,Embelic acid	Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
	Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
TN4221	Homoembelin	2,5-dihydroxy-3-nonyl-1,4-benzoquinone	Antibacterial
	Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) is a pigment from E. ribes and C. monocarpus that has antibacterial effects and can be used to study multidrug-resistant bacterial infections.		Antibacterial
T2S1682	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside	Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside	Amylase
	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.		Amylase
TN6319	Embinin
	Embinin is a natural product for research related to life sciences. The catalog number is TN6319 and the CAS number is 52589-13-6.
T83379	2-Hydroxypinocembrin
	2-Hydroxypinocembrin, a member of the 2-hydroxyflavanones, serves as a substrate for flavonoid C-glycosyltransferases [1].
T19772	Mesembrenone	(+)-Mesembrenone	Others
	Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.		Others
T73857	Mesembrine		Others
	Mesembrine ((+)-Mesembrine), a primary alkaloid distinguished by its aryloctahydroindole structure, acts as a potent 5-HT transporter inhibitor with an inhibition constant (K i) of 1.4 nM. Additionally, it demonstrates i...		Others
T35434	β-Cembrenediol		Others
	β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-ac...		Others
T28019	(-)-Mesembrine	Mesembrin,Mesembrine,Mesembranone	Others
	Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).		Others
TN4792	Pinocembrin diacetate		Others
	Pinocembrin diacetate is a natural product for research related to life sciences. The catalog number is TN4792 and the CAS number is 111441-88-4.		Others
TN4791	Pinocembrin 7-acetate		Others
	Pinocembrin 7-acetate has antitumor activity.		Others
TN7406	Tembetarine		Others
	Tembetarine exhibits anti-inflammatory and anti-injury properties and acts as an antifeedant against S. frugiperda.		Others
T77289	5-O-Methylembelin		Others
	5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9 , low-density lipoprotein receptor (IDOL) , and sterol regulatory element binding protein 2 (SREBP2) mRNA expression [1] .		Others
T72742	(-)-Pinocembrin		Others
	(-)-Pinocembrin demonstrates anti-mycobacterial activity against Mycobacterium tuberculosis H37Ra, presenting IC 50 values of 1.11 mg/mL in the dormant phase and 1.21 mg/mL in the active phase. Additionally, this compoun...		Others
TN5509	(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside	(2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside
	(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside is a natural product for research related to life sciences. The catalog number is TN5509 and the CAS number is 773899-29-9.
T72856	(+)-Cembrene A		Others
	(+)-Cembrene A, a nontoxic α-glucosidase inhibitor to human normal hepatocyte (LO2) cells, exhibits an IC50 value of 30.31 μM.		Others

天然物製品

Ethambutol dihydrochloride

T0810

Synonym: Ethambutol 2HCl,Emb dihydrochloride,CL40881

Target: Antibacterial, Antibiotic, Antifungal

5-MethoxyPinocembroside

Synonym: 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone

Target: NF-κB, Reactive Oxygen Species, Antibacterial, Autophagy

Pinocembrin-7-O-β-D-glucopyranoside

T5710

Synonym: Pinocembrin 7-O-beta-D-glucoside

Target: Others

Pinocembrin chalcone

TN2078

Synonym: 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone

Target: Calcium Channel, Tyrosinase, Antibacterial, Antifection

(+/-)-Pinocembrin

TN2077

Synonym: NSC 43318,(±)-5,7-Dihydroxyflavanone

Target: GPR, Others

Embelin

T6485

Synonym: NSC 91874,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

Homoembelin

TN4221

Synonym: 2,5-dihydroxy-3-nonyl-1,4-benzoquinone

Target: Antibacterial

Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside

T2S1682

Synonym: Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside

Synonym: (+)-Mesembrenone

Synonym: Mesembrin,Mesembrine,Mesembranone

Target: Others

Pinocembrin diacetate

TN4792

Synonym:

Target: Others

Pinocembrin 7-acetate

(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside

TN5509

Synonym: (2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02637	Embigin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane. Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervat...
TMPY-04904	Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)	ZIKV	HEK293 Cells
	Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibit...
TMPH-00023	Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc)	Acinetobacter baumannii	E. coli
	Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of ...
TMPH-00022	Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO)	Acinetobacter baumannii	E. coli
	Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as...
TMPH-01138	Human coronavirus 229E Membrane protein (His)	HCoV-229E	E. coli
	Human coronavirus 229E Membrane protein (His) is expressed in E. coli.
TMPH-03640	34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc)	Treponema pallidum	E. coli
	This antigen is a pathogen-specific membrane immunogen. 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted mo...
TMPH-00021	Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)	Acinetobacter baumannii	P. pastoris (Yeast)
	Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as...
TMPH-01151	Human coronavirus NL63 Membrane protein (His)	HCoV-NL63	E. coli
	Human coronavirus NL63 Membrane protein (His) is expressed in in vitro E. coli expression system.
TMPH-00018	29 kDa outer membrane Protein, Acinetobacter baumannii, Recombinant (His & Myc & SUMO)	Acinetobacter baumannii	E. coli
	May be involved in transporting molecules across the outer membrane.