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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7869 | N-(Hydroxymethyl)nicotinamide | Nicoform,N-hydroxymethylnicotinamide,Bilamid,Nikomethamide,N-(Hytroxymethy)micotinamide | Anti-infection , Antibacterial |
N-(Hydroxymethyl)nicotinamide (Bilamid) is an antimicrobial agent. | |||
T33663 | Nicotinamide Riboside Triflate | SRT 647 Triflate,SRT 647,Nicotinamide Riboside,Nicotinamide Ribose,SRT-647,SRT647,SRT647 Triflate,SRT-647 Triflate | Sirtuin |
Nicotinamide Riboside Triflate (SRT647 Triflate) is a natural NAD precursor that increases NAD levels, enhances oxidative metabolism and prevents obesity induced by a high-fat diet+, and can be used in studies of muscle ... | |||
T20713 | Flonicamid | UNII-9500W2Z53J,N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide | Others |
Flonicamid (N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide), a pyridinecarboxamide insecticide, inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in ... | |||
T69395 | Nicotinamide-d4 | ||
Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized i... | |||
T40060 | Nicotinamide riboside malate | ||
Nicotinamide riboside malate is an orally active NAD+ precursor that elevates NAD+ levels and stimulates the activity of SIRT1 and SIRT3. Functioning as a vitamin B3 (niacin) source, it augments oxidative metabolism and ... | |||
T33662 | Nicotinamide ascorbate | NSC13130,NSC 13130,Nicastubine,NSC-13130 | |
Nicotinamide ascorbate is a bioactive chemical. | |||
T40059 | Nicotinamide riboside tartrate | ||
Nicotinamide riboside tartrate (NRT) is an oral NAD+ precursor that raises NAD+ levels, activates SIRT1 and SIRT3, and serves as a vitamin B3 (niacin) source. NRT also improves oxidative metabolism and protects against m... | |||
T72188 | Nicotinamide Hydrochloride | Niacinamide Hydrochloride,Nicotinic acid amide Hydrochloride,Niacinamide Hydrochloride ; Nicotinic acid amide Hydrochloride | |
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin that inhibits sirtuin 2 ( SIRT2 ) activity in vitro , with an EC 50 of 2 μM. Nicotinamide Hydrochloride inhibits up to 90% melanoma cell number and increases c... | |||
T78408 | Nicotinamide 1,N6-ethenoadenine dinucleotide | ε-NAD | |
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD), a fluorescent NAD analogue, functions as a substrate in bacterial toxin-catalyzed G-ADP ribosylation of G-proteins involved in signal transduction. It is also applica... | |||
T33666 | Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride | ||
Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical. | |||
T33664 | Nicotinamide, N-(2-pyridyl)- | AI315755,AI3-15755,AI3 15755 | |
Nicotinamide, N-(2-pyridyl)- is a biochemical. | |||
T33665 | Nicotinamide, N-(5-(p-aminophenoxy)pentyl)- | ||
Nicotinamide, N-(5-(p-aminophenoxy)pentyl)- is a bioactive chemical. | |||
T65332 | N-(2-Hydroxyethyl)nicotinamide | ||
N-(2-Hydroxyethyl)nicotinamide is a useful organic compound for research related to life sciences. The catalog number is T65332 and the CAS number is 6265-73-2. | |||
T77253 | β-Nicotinamide adenine dinucleotide reduced dipotassium | ||
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active, reduced coenzyme that functions as a donor of ADP-ribose units in ADP-ribosylation reactions, and as a precursor of cyclic ADP-ribose. It also ... | |||
T12854 | SBI-797812 | NAMPT | |
SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM). | |||
T83800 | 6-Biotin-17-NAD+ sodium | 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide | |
6-Biotin-17-NAD+, a biotinylated derivative of the signaling molecule and enzyme cofactor NAD+, is utilized in high-throughput screening (HTS) assays to measure the activity of mitochondrial complex I, also referred to a... | |||
T83799 | 6-alkyne NAD+ sodium | β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD | |
6-alkyne NAD+, a clickable variant of the signaling molecule and enzyme cofactor NAD+, facilitates the fluorescent tagging for the detection of poly(ADP-ribose) polymerase (PARP) protein substrates. | |||
T83798 | 8-bromo NAD+ sodium | 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+ | |
8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in in... | |||
T7545 | 6-Aminonicotinamide | Others | |
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme. | |||
T31261 | Deaminocozymase | Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN | |
Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical. | |||
T83845 | 8-(4-azidophenacylthio) NAD+ sodium | Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide | |
8-(4-Azidophenacylthio) NAD+ is a clickable variant of the essential signaling molecule and enzyme cofactor, NAD+. | |||
T83844 | 8-(2-azidobenzylthio) NAD+ sodium | 8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+ | |
8-(2-azidobenzylthio) NAD+ is a derivatized version of NAD+, a signaling molecule and enzyme cofactor, featuring an azido group (azidobenzylthio) that enables click chemistry applications. | |||
T4335 | GNE-617 | GNE617 | NAMPT |
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer. | |||
T12171 | Nampt-IN-5 | P450 , NAMPT | |
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) . | |||
T6682 | STF-118804 | STF 118804,STF118804 | Apoptosis , NAMPT |
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM. | |||
T4376 | Nampt-IN-1 | LSN3154567 | c-Fms , NAMPT , CSF-1R |
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. | |||
T1998 | CHS-828 | CHS 828,GMX1778 | Apoptosis , NAMPT |
CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM). | |||
T2644 | (E)-Daporinad | Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866 | NAMPT , Transferase , Autophagy |
(E)-Daporinad (FK866) is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities. | |||
T39195 | YM-244769 dihydrochloride | Calcium Channel | |
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys. | |||
T9888 | YM-244769 | 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- | Calcium Channel |
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec... | |||
T1365 | Thioisonicotinamide | Pyridine-4-carbothioamide,Isothionicotinamide,4-Pyridylthiocarboxamide | Antibiotic |
Thioisonicotinamide (Isothionicotinamide) is a chemical based on the nicotinamide structure, but in which the amide is in the 4-position and not the 3-position. | |||
T0552 | Isonicotinamide | Others | |
Isonicotinamide is used as pharmaceutical intermediate to synthesis Cefalonium, etc. | |||
T9735 | 6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide | Others | |
6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide can be used in the synthesis of befetupitant and netupitant. | |||
T37046 | 1-Methyl-1,4-dihydronicotinamide | ||
1-Methyl-1,4-dihydronicotinamide is a nicotinamide derivative. Its product number is T37046 and CAS number is 17750-23-1. | |||
T32222 | Isonicotinamide, N-(3-difluoromethoxyphenyl)-, hydrochloride | ||
Isonicotinamide, N-(3-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical. | |||
T32223 | Isonicotinamide, N-(5-(p-aminophenoxy)pentyl)- | ||
Isonicotinamide, N-(5-(p-aminophenoxy)pentyl)- is a bioactive chemical. | |||
T124246 | 1,4-Dihydro-1-methyl-4-oxonicotinamide | ||
1,4-Dihydro-1-methyl-4-oxonicotinamide is a useful organic compound for research related to life sciences. The catalog number is T124246 and the CAS number is 769-49-3. | |||
TP2083L | Ac9-25 acetate | Ac9-25 acetate(284040-76-2 free base) | Others |
Ac9-25 acetate is an annexin AI peptide and activates the neutrophil reduced nicotinamide adenine dinucleotide phosphate oxidase through FPR but not through FPRL1. | |||
T20466 | Keto-pantoyllactone | Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione | Others |
Keto-pantoyllactone (Dihydro-4,4-dimethyl-2,3-furandione) is assayed by the ketopantoyl lactone-dependent oxidation of nicotinamide adenine dinucleotide phosphate. | |||
T1833 | NSI189 | NSI-189,NSI 189 | Others |
NSI189 (NSI-189) is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine. | |||
T1880 | P7C3 | Others | |
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be... | |||
T8106 | JBSNF-000088 | JBSNF000088 | Others |
JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders. | |||
T80799 | WAY-620147 | MAO | |
WAY-620147 is a derivative of N-(2-morpholinoethyl)nicotinamide, which is able to inhibit Monoamine Oxidase.WAY-620147 has an IC50 value of 26 μM for MAO-A and 55 μM for MAO-B, and can be used for the study of neurologic... | |||
T11143 | EB-47 | PARP | |
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC... | |||
T33565 | NAAD sodium salt | NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD | |
NAAD sodium salt (NAAD Na salt) is a substrate of nicotinamide adenine dinucleotide synthase and can be used in studies about the specificity and kinetics of the substrate. | |||
T8760 | NNMTi | 5-Amino-1-methylquinolinium | Others |
NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adip... | |||
T10247 | Adenosine 5'-diphosphoribose sodium | Adenosine 5'-diphosphoribose sodium,ADP ribose sodium | Endogenous Metabolite , TRP/TRPV Channel , Autophagy |
T7092 | NADPH tetrasodium salt | Others , Ferroptosis , Endogenous Metabolite | |
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an end... | |||
T72947 | JBSNF-000028 | JBSNF-000028 free base | Others |
JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, a... | |||
T12781 | RV01 | Others | |
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T0617 | Nicotinamide N-oxide | Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide | c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite |
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n... | |||
T4721 | β-Nicotinamide mononucleotide | β-NM | Others , Endogenous Metabolite |
β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD... | |||
T13795 | Nicotinamide riboside | Sirtuin | |
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. | |||
T6220 | Nicotinamide riboside chloride | Sirtuin , Endogenous Metabolite | |
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. | |||
T1609 | NAD+ | Cozymase,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD | NADPH , Endogenous Metabolite |
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous... | |||
T4853 | TRIA-662 | 3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate | Others , Endogenous Metabolite |
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system. | |||
T8150 | Nudifloramide | 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide | PARP , Endogenous Metabolite |
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD). | |||
T5233 | N-Methylnicotinamide | N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide | Others , Endogenous Metabolite |
N-Methylnicotinamide (Nicotinic Acid Methylamide) is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-Methylnicotinamide (Nicotinic Acid Methylam... | |||
T66582 | 6-Methylnicotinamide | Endogenous Metabolite | |
6-Methylnicotinamide is a derivative of nicotinamide, an endogenous metabolite. 6-Methylnicotinamide is used to make co-crystals/salts. In the acute phase of cerebral hemorrhage (ICH), a sudden increase in 6-Methylnicoti... | |||
T22446 | NADP disodium salt | Disodium NADP,Triphosphopyridine nucleotide disodium salt | Others |
NADP disodium salt (Disodium NADP) is a nicotinamide adenine dinucleotide. NADP disodium salt is a key redox cofactor for electron transfer in the metabolism, serves as an electron carrier in a number of reactions, being... | |||
T5283 | NADH disodium salt | Disodium NADH,NADH, disodium salt hydrate | Others , Endogenous Metabolite |
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid... | |||
T0879 | Niacin | Vitamin B3,Nicotinic acid | Endogenous Metabolite , Autophagy |
Niacin (Nicotinic acid) is a water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, w... | |||
T1165 | Ethionamide | Bayer 5312,2-ethylthioisonicotinamide,Ethinamide | Dehydrogenase , CAT , Antibacterial , Antibiotic |
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthes... | |||
TN4488 | Mallorepine | Others | |
Mallorepine may propably be an intermediate on the biosynthetic pathway from nicotinamide (II) to ricinine (III). | |||
TN2725 | 2',5,6',7-Tetrahydroxyflavanone | Others | |
(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03406 | NMNAT1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to pro... | |||
TMPY-02577 | NAMPT Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferas... | |||
TMPJ-00968 | NAMPT Protein, Human, Recombinant (His) | Human | E. coli |
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular e... | |||
TMPH-03449 | Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibito... | |||
TMPH-02811 | NRK1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). | |||
TMPH-03450 | Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant | Saccharomyces cerevisiae | E. coli |
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibito... | |||
TMPH-00673 | NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph... | |||
TMPY-02519 | BLVRB Protein, Human, Recombinant (His) | Human | E. coli |
Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann... | |||
TMPH-00207 | PTX S1 Protein, Bordetella pertussis, Recombinant (His) | Bordetella pertussis | P. pastoris (Yeast) |
S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the a... | |||
TMPJ-00462 | NADK Protein, Human, Recombinant (His) | Human | E. coli |
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through... | |||
TMPJ-00836 | G6PD Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by ... | |||
TMPJ-00848 | NCF1 Protein, Human, Recombinant (His) | Human | E. coli |
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem... | |||
TMPJ-00473 | QPRTase Protein, Human, Recombinant (His) | Human | E. coli |
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ... |