検索結果

Search Results for " adiponectin "

ターゲット

Adiponectin receptor Adiponectin receptor

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T2257	AdipoRon	SC-396658	Adiponectin receptor
	AdipoRon (SC-396658) is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).		Adiponectin receptor
T27228	E-3030 free acid	E-3030,E3030,E 3030
	E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Trigly...
T61417	PPARγ agonist 7
	PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It specifically stimulates adiponectin production in human bone marrow mesenchymal s...
T78633	MeOSuc-AAPV-CMK	Elastase Inhibitor III
	MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated cleavage of adiponectin [1].

Compounds

AdipoRon

T2257

Synonym: SC-396658

Target: Adiponectin receptor

E-3030 free acid

T27228

Synonym: E-3030,E3030,E 3030

Synonym: Elastase Inhibitor III

Target:

カタログ番号	製品名	別名	ターゲット
T6519	Gramine	NSC 16892,Donaxine	Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor
	Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als...
T1079	Metronidazole	Flagyl,Metronidazol,Anagiardil	Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection
	Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
TN2121	3,5,7,3′,4′-Pentamethoxyflavone	Quercetin 3,5,7,3,4-pentamethyl ether	Others
	3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation.		Others
T2755	Rhoifolin	Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
	Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
TQ0171	Isoastragaloside I		Others
	Isoastragaloside I is a natural product,has the enhancement adiponectin quantity activity.		Others
T4S0295	Apigenin 7-glucoside	Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin	Reactive Oxygen Species , HIV Protease
	1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 tr...		Reactive Oxygen Species , HIV Protease
T2766	Arctiin	Arctigenin-4-glucoside,Arctii,NSC 315527	Adiponectin receptor
	Arctiin (Arctigenin-4-glucoside) acts on an agonists of the adiponectin receptor 1 with anti-cancer effects.		Adiponectin receptor
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
TN5137	Tetramethylkaempferol		transporter , PPAR
	Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempfero...		transporter , PPAR
T2S2173	(E)-Naringenin chalcone	Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone	Others
	Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha...		Others
T5S1172	Tiliroside	Tribuloside	Antioxidant
	1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati...		Antioxidant
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T20232	Kazinol B		Akt , NO Synthase , AMPK
	Kazinol B is an inhibitor of nitric oxide (NO) production, an isopentenylated flavan with a dimethylpyran ring.Kazinol B improves insulin sensitivity by activating the insulin-Akt signalling pathway and AMPK, which enhan...		Akt , NO Synthase , AMPK

天然物製品

Gramine

T6519

Synonym: NSC 16892,Donaxine

Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor

Metronidazole

T1079

Synonym: Flagyl,Metronidazol,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

3,5,7,3′,4′-Pentamethoxyflavone

TN2121

Synonym: Quercetin 3,5,7,3,4-pentamethyl ether

Target: Others

Rhoifolin

T2755

Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

Synonym: Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin

Target: Reactive Oxygen Species, HIV Protease

Arctiin

T2766

Synonym: Arctigenin-4-glucoside,Arctii,NSC 315527

Target: Adiponectin receptor

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

Tetramethylkaempferol

TN5137

Synonym:

Target: transporter, PPAR

(E)-Naringenin chalcone

T2S2173

Synonym: Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone

Target: ERK, Dehydrogenase, NF-κB

Kazinol B

T20232

Synonym:

Target: Akt, NO Synthase, AMPK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02848	Adiponectin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848.
TMPY-05556	Adiponectin Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Adiponectin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A8K660.
TMPK-00139	Adiponectin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Adiponectin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.3 kDa and the accession number is Q60994.
TMPY-01681	Adiponectin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Adiponectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is Q60994.
TMPK-00554	Adiponectin Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Adiponectin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.76 kDa and the accession number is A0A2K5X7X6.
TMPH-00350	Adiponectin Protein, Feline, Recombinant	Feline	E. coli
	Adiponectin Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 24.9 kDa and the accession number is A4PB30.
TMPH-00219	Adiponectin Protein, Bovine, Recombinant (His)	Bovine	P. pastoris (Yeast)
	Adiponectin Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q3Y5Z3.
TMPH-00905	ADIPOR1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	ADIPOR1 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in in vitro E. coli expression system.
TMPJ-01304	C1QTNF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-termin...