|
T8734 |
Choline
|
|
Others
|
|
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins |
|
T8129 |
Potassium acetate
|
Diuretic salt,Potassium ethanoate |
Antifungal
|
|
Potassium acetate (Diuretic salt) with antibacterial and antifungal properties. |
|
T18888 |
4-Methylumbelliferyl phosphate
|
4-MUP |
Others
|
|
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases. |
|
T60254 |
Calcium glycerophosphate
|
|
Phosphorylase
|
|
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2]. |
|
T0745 |
Disodium monofluorophosphate
|
Sodium Monofluorophosphate,NSC248 |
Phosphatase
,
PKM
,
Phosphorylase
|
|
Disodium monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase. |
|
T24821 |
Spizofurone
|
Espizofurona,AG-629 |
Others
|
|
Spizofurone (Espizofurona) has antiulcer activity, protective effect on the gastric mucosa of rats, and can increase alkaline secretion in isolated bullfrog duodenal mucosa. |
|
T0017 |
Phenolphthalein
|
Euchessina,Phthalimetten,Phthalin |
Others
|
|
Phenolphthalein (Phthalin) is an acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic. |
|
T14280 |
AMPPD
|
Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus |
Others
|
|
AMPPD (Lumi-Phos Plus) is a 1,2-dioxo-cyclohexane derivative and a substrate for hypersensitive alkaline phosphatase. |
|
T6353 |
(-)-p-Bromotetramisole Oxalate
|
L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate |
Phosphatase
,
Phosphorylase
|
|
(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) is a potent and non-specific inhibitor of alkaline phosphatase. |
|
T75349 |
CDP-Star
|
|
|
|
CDP-Star, a chemiluminescent substrate specifically designed for alkaline phosphatase, is effectively utilized in enzyme-linked immunoassays (ELISA) [1]. |
|
T16554 |
PNPP
|
|
Others
|
|
PNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. |
|
T16859 |
SBI-425
|
|
Others
|
|
SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival withou... |
|
T18923 |
BCIP
|
BCIP p-toluidine salt,X-phosphate p-toluidine salt |
Others
|
|
BCIP (BCIP p-toluidine salt) (BCIP p-toluidine salt) is an artificial chromogenic substrate. It is used for the sensitive colorimetric detection of alkaline phosphatase activity. |
|
T8321 |
10-methyl-9-(phenoxycarbonyl) Acridinium
|
|
Others
|
|
10-methyl-9-(phenoxycarbonyl) Acridinium is an acridinium ester that produces fluorescent 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfates, and other oxidants in alkaline conditions |
|
T21969 |
ML-095 hydrochloride
|
CID-25067483 hydrochloride,MLS-0315848 hydrochloride |
Phospholipase
|
|
ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor. It inhibits PLAP, TNAP and IAP with IC50 of 2.1, >100 and 53 μM, respectively. |
|
T20913 |
Light Green SF Yellowish
|
Acid Green 5,C.I. Acid Green 5,C.I. 42095 |
|
|
Light Green SF Yellowish (Acid Green 5) is an alkaline stain used for staining animal tissues and for cytoplasmic and fiber staining in plant histology. |
|
T34093 |
PNNP
|
p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate |
Carbonic Anhydrase
|
|
pNNP (Nitrophenylphosphate) can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori Helicobacter pylori. pNNP is a weakly active, tissue-nonsp... |
|
T67886 |
Girard's Reagent T
|
Trimethylacetohydrazideammonium Chloride |
Others
|
|
Girard's Reagent T (Trimethylacetohydrazideammonium Chloride) is a biochemical reagent. Girard's Reagent T under mild acid or alkaline conditions, reacts with aldehydes and ketones containing α-dicarbonyl functional grou... |
|
T11048L |
DIPQUO hydrochloride
|
DIPQUO hydrochloride(1269365-82-3 Free base) |
Phosphorylase
|
|
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 M... |
|
T19032 |
Nitro blue tetrazolium chloride
|
NBT |
NO Synthase
|
|
Nitro blue tetrazolium chloride (NBT) is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 M). A well-known scavenger of superoxide anions.Nitro blue tetrazolium chloride, a subst... |
|
T0192 |
Levetiracetam
|
UCB L059,SIB-S1 |
DNA Methyltransferase
,
Others
,
Calcium Channel
|
|
Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been linked to rare instances of serum... |
|
T25883 |
N-Retinoylphenylalanine
|
N-Retinoyl-phe |
|
|
N-Retinoylphenylalanine is an inhibitor of alkaline phosphatase isoenzymes. |
|
T20544 |
C.I. 21010
|
C.I.-21010,C.I.21010 |
|
|
C.I. 21010 is an alkaline dye. |
|
T20421 |
Fluorescein diphosphate
|
Fluorescein diphosphate Tetraammonium salt,FDP |
|
|
Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluores... |
|
T25056 |
Alphostatin
|
|
|
|
Alphostatin is an alkaline phosphatase inhibitor isolated from Bacillus megaterium. |
|
T40593 |
5-FAM-Alkyne
|
|
|
|
5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor designed for detecting alkaline phosphatase (ALP). |
|
T37056 |
D-erythro-MAPP
|
|
|
|
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon... |
|
T11048 |
DIPQUO
|
|
Others
|
|
DIPQUO is an activator of bone marker alkaline phosphatase (ALP). DIPQUO promotes the differentiation of mouse and human osteoblasts by activating p38MAPK-β. The EC50 in C2C12 cells was 6.27 μM. |
|
TD0057 |
5-TRITC
|
G isomer [Tetramethylrhodamine-5-isothiocyanate] |
|
|
5-TRITC can bind to various antibody proteins, and the antibody does not lose its specificity of binding to certain antigens, and has a strong yellow-green fluorescence in alkaline solution. |
|
T38337 |
Isochlortetracycline
|
|
|
|
Isochlortetracycline is an inactive alkaline product of the degradation of the broad-spectrum antibiotic chlortetracycline. |
|
TD0058 |
6-TRITC
|
R isomer [Tetramethylrhodamine-6-isothiocyanate] |
|
|
6-TRITC can bind to various antibody proteins, and the antibody does not lose its specificity of binding to certain antigens, and has a strong yellow-green fluorescence in alkaline solution. |
|
T78386 |
4-Methylumbelliferyl oleate
|
|
|
|
4-Methylumbelliferyl oleate serves as a fluorogenic substrate for both acid and alkaline lipases, which cleave the compound to release 4-Methylumbelliferyl (Ex/Em=320/450 nm) [1] [2]. |
|
T75366 |
Naphthol AS-GR phosphate disodium
|
|
|
|
Naphthol AS-GR phosphate disodium, a substrate for both acid and alkaline phosphatases, exhibits intense green fluorescence, making it valuable for histochemical studies [1]. |
|
T11314 |
Fosmanogepix
|
APX001,E1211 |
Others
|
|
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This... |
|
T35969 |
NOC-5
|
|
|
|
NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. [1] The half-life of NOC-5 in PBS (pH 7.4) is... |
|
T69066 |
Forphenicine
|
|
|
|
Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 µg/ml for the chicken intestine enzyme). It inhibits the growth of HL-60 leukemia cells... |
|
T75340 |
4-Methylumbelliferyl phosphate disodium
|
|
|
|
4-Methylumbelliferyl phosphate disodium (4-MUP), an anionic organophosphate, serves as a fluorogenic substrate for acid and alkaline phosphatases. Additionally, this compound acts as a simulant for nerve agents [1] [2] [... |
|
T63568 |
PLAP-IN-1
|
|
|
|
PLAP-IN-1 is a potent and selective PLAP inhibitor with an IC50 value of 32 nM and no significant inhibitory effect on tissue non-specific alkaline phosphatase (TNAP) activity. |
|
T19390 |
L-Ascorbic acid 2-phosphate
|
2-Phospho-L-ascorbic acid |
Others
|
|
L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and... |
|
T37616 |
Leukotriene A4 methyl ester
|
Leukotriene A4 methyl ester |
|
|
Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies. |
|
T20104 |
C.I. 37545
|
NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes |
|
|
C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoaz... |
|
T36410 |
9(E),11(E),13(E)-Octadecatrienoic Acid
|
|
|
|
9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linole... |
|
T78924 |
TPE-1p
|
|
|
|
TPE-1p, a cascade-activated AIEgen-peptide probe, self-assembles in aqueous solution to produce bright fluorescence upon interaction with alkaline phosphatase (ALP) and ChT-L. It facilitates noninvasive evaluation of ChT... |
|
T76660 |
PTH (1-37) (human)
|
|
|
|
pTH (1-37) (human), a fragment of parathyroid hormone (PTH), promotes cAMP formation and enhances alkaline phosphatase activity. Additionally, it fosters growth, elevates bone calcium content, and augments bone mineral d... |
|
T82147 |
Hydroxy naphthol blue disodium
|
|
|
|
Hydroxy naphthol blue disodium, an azo dye functioning as a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions (λmax = 650 nm), exhibits a reddish-pink color in solutions containing calc... |
|
T83137 |
ALP/Carbonic anhydrase-IN-1
|
|
Carbonic Anhydrase
|
|
Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0.... |
|
T35777 |
Nodularin
|
|
|
|
The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatot... |
|
T75377 |
Thymolphthalein monophosphate disodium hydrate
|
|
|
|
Thymolphthalein monophosphate disodium hydrate serves as a chromogenic substrate for the detection of acid phosphatase and alkaline phosphatase. During the enzymatic reaction, thymolphthalein is liberated which elevates ... |
|
T36714 |
Sucrose octasulfate (potassium salt)
|
|
|
|
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium agains... |
|
T83675 |
Thio-NAD
|
Thionicotinamide NAD,Thionicotinamide adenine dinucleotide |
|
|
Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual... |
