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Search Results for " assembly "

ターゲット

HBV

118

阻害剤

天然化合物

154

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T16366	NVR 3-778		HBV
	NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.		HBV
T1008	Cephalexin	Cefalexin,Cephacillin	Antibacterial , Antibiotic
	Cephalexin (Cephacillin) is a cephalosporin antibiotic.		Antibacterial , Antibiotic
T17011	TCH-165		Proteasome
	TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.		Proteasome
T0204	Protriptyline hydrochloride	Protriptyline HCl	5-HT Receptor , AChE
	Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph...		5-HT Receptor , AChE
T6439	Cetylpyridinium Chloride	Cetamium,Pristacin,Hexadecylpyridinium Chloride	Others , HBV , Antibacterial
	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.		Others , HBV , Antibacterial
T4475	JNJ-632		HBV
	JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.		HBV
T16788	Rosabulin	STA 5312	Others , Microtubule Associated
	v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity.		Others , Microtubule Associated
TP1159L	Boc-Gly-Gly-Phe-Gly-OH acetate	Boc-Gly-Gly-Phe-Gly-OH acetate(187794-49-6 free base),GGFG acetate
	Boc-Gly-Gly-Phe-Gly-OH acetate (GGFG acetate) is a self-assembly of N- and C-protected tetrapeptide.
T6071	Parbendazole	SKF 29044	Microtubule Associated , Parasite
	Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.		Microtubule Associated , Parasite
T78557	HOIPIN-1	JTP0819958	NF-κB
	HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.		NF-κB
TQ0017	AB-423		HBV
	AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).		HBV
T28506	Rbin-2		Phosphatase
	Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study...		Phosphatase
T3628	Madrasin	DDD00107587	DNA/RNA Synthesis
	Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.		DNA/RNA Synthesis
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].		IκB/IKK
T25214	CCR-11	CCR11,CCR 11	Antibiotic
	CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit...		Antibiotic
T11409	GLP-26		HBV
	GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...		HBV
T6267	Lomitapide	AEGR-733,BMS-201038	CETP
	Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring...		CETP
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T60487	DDO-7263		Nrf2
	DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator th...		Nrf2
T15713	Larotaxel	XRP9881	P-gp
	Larotaxel (XRP9881) is a taxane analogue that has anticancer activity, exerts its cytotoxic effects by promoting tubulin assembly and stabilizing microtubules, and ultimately induces cell death through apoptosis. Larotax...		P-gp
T2162	Maribavir	BW1263W94,GW257406X,Benzimidavir,1263W94	Others , HCV Protease
	Maribavir (GW257406X) is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nucle...		Others , HCV Protease
T15576	Indibulin	ZIO 301,D 24851	Apoptosis , Microtubule Associated
	Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...		Apoptosis , Microtubule Associated
T72083	Octadecyl Rhodamine B chloride
	Octadecyl Rhodamine B chloride, also known as RBOE, is a polarity-sensitive dye that is often used as a chromophore with other compounds to stain cell membranes and has applications in the assembly of organic molecules, ...
T2511	Plinabulin	NPI-2358	Microtubule Associated
	Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, the...		Microtubule Associated
T3317	SZL P1-41		Apoptosis , Others , E1/E2/E3 Enzyme
	SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediate...		Apoptosis , Others , E1/E2/E3 Enzyme
T16500	PF-3450074	PF-74	HIV Protease
	PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu...		HIV Protease
T10446	BA-53038B		Others
	BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).		Others
TP2360	A2-Binding peptide
	A2-Binding peptide has involved in the assembly of MHC Class I molecules.
T71584	Microtubule Inhibitor 185322
	Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
T28821	SMR000071098	SMR-000071098,SMR 000071098
	SMR000071098 is an inhibitor of Fe-S cluster-dependent aconitase. SMR000071098 interacts with Suf proteins to inhibit iron-sulfur (Fe-S) cluster assembly.
T71203	JBIR-22
	JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.
T28288	Pacidamycin I	A-68567,A 68567,A68567
	Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.
TP1159	Boc-Gly-Gly-Phe-Gly-OH	GGFG
	Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide.
T14800	Bromo-PEG3-phosphonic acid diethyl ester		Others
	Bromo-PEG3-phosphonic acid diethyl ester is a polyethylene glycol (PEG) derivative commonly employed as a linker for the assembly of proteolysis targeting chimeras (PROTACs)[1].		Others
T29198	Z060228	Z 060228,Z-060228
	Z060228 is an potent anti-HBV inhibitor. The HBV DNA replication was effectively inhibited by Z060228 in the supernatants of the HepG2.2.15 cells. Z060228 exhibited effects on the self-assembly of Cp149. SEC data reveale...
T26756	BCM-599	BCM 599
	BCM-599 is a HBV capsid assembly inhibitor. BCM-599 showed IC50 of 0.88 μM and CC50 of 144 μM in HepG2.2.15 cells.
T79270	TMV-IN-6
	TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat protein (CP) and disrupting the assembly interaction between...
T80243	Gp91 ds-tat
	Gp91phox ds-tat, a biologically active peptide, functions as an inhibitor of NADPH oxidase assembly.
T26076	Rhizoxin	WF1360,WF 1360,WF-1360
	Rhizoxin is an antitumor drug isolated from the fungus Rhizopus chinensis. It is a macrocyclic lactone compound that binds to tubulin and inhibits microtubule assembly.
T62467	HBV-IN-18
	HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).
TP2117	SAHM1
	Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.
TP1643	Alpha 1(I) Collagen (614-639), human
	This is a peptide inhibitor of collagen fibrillar matrix assembly.
T28860	ST-148	ST148
	ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
T76054	SAHM1 TFA
	SAHM1 TFA is a chemical compound that acts as a Notch pathway inhibitor by stabilizing a hydrocarbon-stapled alpha helical peptide. It specifically targets the protein-protein interface, effectively preventing the assemb...
T21321	MK-0731
	MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during...
T16997	Tasidotin hydrochloride	ILX651	Microtubule Associated
	Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and microtubule dynamics.		Microtubule Associated
T9769	Bersacapavir(JNJ-56136379)
	Bersacapavir is a novel Hepatitis B Virus capsid assembly modulator in vitro with a dual mode of action[1].
T60730	BA38017
	BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].
T18325	MC-Val-Cit-PAB-Indibulin		Others
	MC-Val-Cit-PAB-Indibulin is an antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), featuring the orally active tubulin assembly inhibitor, Indibulin, connected through the MC-Val-Cit-PAB ADC linker. This...		Others
T68570	TPI-287
	TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cyc...

Compounds

Synonym: Cefalexin,Cephacillin

Target: Antibacterial, Antibiotic

Protriptyline hydrochloride

T0204

Synonym: Protriptyline HCl

Target: 5-HT Receptor, AChE

Cetylpyridinium Chloride

T6439

Synonym: Cetamium,Pristacin,Hexadecylpyridinium Chloride

Target: Others, HBV, Antibacterial

Target: Others, Microtubule Associated

Boc-Gly-Gly-Phe-Gly-OH acetate

TP1159L

Synonym: Boc-Gly-Gly-Phe-Gly-OH acetate(187794-49-6 free base),GGFG acetate

Target: Microtubule Associated, Parasite

Target: DNA/RNA Synthesis

JTP 0819958 - HOIPIN-1

Synonym: CCR11,CCR 11

Synonym: AEGR-733,BMS-201038

Target: CETP

Carbendazim

T3124

Synonym: Bavistin,Carbendazole,Mercarzole

Synonym: BW1263W94,GW257406X,Benzimidavir,1263W94

Target: Others, HCV Protease

Indibulin

T15576

Synonym: ZIO 301,D 24851

Target: Apoptosis, Microtubule Associated

Octadecyl Rhodamine B chloride

Target: Microtubule Associated

SZL P1-41

T3317

Synonym:

Target: Apoptosis, Others, E1/E2/E3 Enzyme

Microtubule Inhibitor 185322

Synonym: SMR-000071098,SMR 000071098

Synonym: A-68567,A 68567,A68567

Target:

Boc-Gly-Gly-Phe-Gly-OH

TP1159

Synonym: GGFG

Target:

Bromo-PEG3-phosphonic acid diethyl ester

Synonym: Z 060228,Z-060228

Synonym: WF1360,WF 1360,WF-1360

Alpha 1(I) Collagen (614-639), human

Tasidotin hydrochloride

T16997

Synonym: ILX651

Target: Microtubule Associated

Bersacapavir(JNJ-56136379)

MC-Val-Cit-PAB-Indibulin

カタログ番号	製品名	別名	ターゲット
TN7041	(-)-Epipodophyllotoxin		Apoptosis
	(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit...		Apoptosis
T2773	Vindoline		Microtubule Associated
	Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.		Microtubule Associated
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T2937	4'-Demethylepipodophyllotoxin	4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin	Microtubule Associated
	4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.		Microtubule Associated
T36850	Curvulin		Microtubule Associated
	Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.		Microtubule Associated
T16016	Maytansinol	Ansamitocin P-0	Apoptosis , Microtubule Associated
	Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.		Apoptosis , Microtubule Associated
T21351	Maytansine	NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine	Microtubule Associated , Antibiotic
	Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.		Microtubule Associated , Antibiotic
T4S0181	Hinokiflavone		MMP , BCL , E1/E2/E3 Enzyme
	Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO...		MMP , BCL , E1/E2/E3 Enzyme
TN5107	Taxcultine		Others
	Taxcultine can actively promote tubulin assembly.		Others
T10928	Cytochalasin A		HIV Protease
	Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubu...		HIV Protease
T2S1797	Santalol		Antioxidant , Antifungal
	1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal ef...		Antioxidant , Antifungal

天然物製品

(-)-Epipodophyllotoxin

Target: Microtubule Associated

Pseudouridine

T16674

Synonym:

Target: Endogenous Metabolite

4'-Demethylepipodophyllotoxin

T2937

Synonym: 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin

Target: Microtubule Associated

Curvulin

T36850

Synonym:

Target: Microtubule Associated

Maytansinol

T16016

Synonym: Ansamitocin P-0

Target: Apoptosis, Microtubule Associated

Maytansine

T21351

Synonym: NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine

Target: Microtubule Associated, Antibiotic

Hinokiflavone

T4S0181

Synonym:

Target: MMP, BCL, E1/E2/E3 Enzyme

Target: Antioxidant, Antifungal

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00699	BamA Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	BamA Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 30 kDa and the accession number is P0A940.
TMPH-00675	BamA Protein, E. coli O157:H7, Recombinant (His)	E. coli	E. coli
	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. BamA...
TMPH-00700	BamA Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	BamA Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.0 kDa and the accession number is P0A940.
TMPH-00930	Anamorsin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Anamorsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q6FI81.
TMPH-00942	AP1B1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	AP1B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-05822	Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)	HBV-D	E. coli
	Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ...
TMPY-04329	Vimentin Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers ...
TMPH-00527	Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)	Enterobacteria phage T4	E. coli
	Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to th...
TMPH-00650	LptE Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer...
TMPJ-01399	ASF1A Protein, Human, Recombinant (His, T7)	Human	E. coli
	Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chrom...
TMPH-02184	Telethonin Protein, Human, Recombinant (GST)	Human	E. coli
	Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk. Telethonin Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST t...
TMPH-01673	Human metapneumovirus (strain CAN97-83) Matrix protein (His)	HMPV	P. pastoris (Yeast)
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti...
TMPH-01672	Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)	HMPV	E. coli
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti...
TMPH-02382	Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)	MARV	E. coli
	Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 ...
TMPH-01803	NAP1L4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Acts as histone chaperone in nucleosome assembly. NAP1L4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.1 kDa and the a...
TMPH-02548	Biglycan Protein, Mouse, Recombinant (His)	Mouse	E. coli
	May be involved in collagen fiber assembly. Biglycan Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P...
TMPH-02381	SlpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc)	Lactobacillus acidophilus	E. coli
	The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
TMPH-00529	UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His)	Enterobacteria phage T4	E. coli
	Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA.
TMPH-01253	DCTN3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Together with dynein may be involved in spindle assembly and cytokinesis. DCTN3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is ...
TMPH-01790	NUP210 Protein, Human, Recombinant (His)	Human	E. coli
	Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. NUP210 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The ...
TMPH-00530	SSB Protein, Enterobacteria phage T4, Recombinant (His & Myc)	Enterobacteria phage T4	E. coli
	Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair (Probable). Coats the lagging-strand ssDNA as the replication fork advances. Stimulates the activities of viral DN...
TMPJ-00972	CDKN1B Protein, Human, Recombinant (His)	Human	E. coli
	Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele...
TMPH-00648	LapB Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote...
TMPY-04073	MRPL44 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPH-02687	Granzyme A/GZMA Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or ...
TMPH-02966	UPK2 Protein, Mouse, Recombinant (GST & His)	Mouse	E. coli
	Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. UPK2 Protein, ...
TMPH-01100	CLINT1 Protein, Human, Recombinant (His)	Human	E. coli
	Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. CLI...
TMPH-02519	API5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently supp...
TMPH-00516	StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)	Enterobacteria phage 933W	E. coli
	The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the cata...
TMPH-00649	LptA Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interact...
TMPH-02709	SAP130 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. SAP130 Protei...
TMPJ-01302	ACAT2 Protein, Human, Recombinant (His)	Human	E. coli
	ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi...
TMPH-01823	PERP Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway....
TMPY-03749	LC3B Protein, Human, Recombinant (His)	Human	E. coli
	MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 beta, also known as LC3B) is a Protein Coding gene. The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are in...
TMPH-02177	Tapasin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). Tapasin Protein, Human, Recombinant (His & Myc) is e...
TMPH-00325	S-layer Protein, Campylobacter fetus, Recombinant (His & Myc)	Campylobacter fetus	E. coli
	The S-layer is a paracrystalline mono-layered assembly of proteins which coats the surface of bacteria. This protein is critical for virulence. S-layer Protein, Campylobacter fetus, Recombinant (His & Myc) is expressed i...
TMPY-03751	C1orf33/MRTO4 Protein, Human, Recombinant (His)	Human	E. coli
	MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence si...
TMPH-01691	TOMM40 Protein, Human, Recombinant (GST)	Human	E. coli
	Channel-forming protein essential for import of protein precursors into mitochondria. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with ...
TMPK-00657	SPARC Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM40) is one of the most abundant non-collagenous protein expressed in mineralized tissues.The capacity of SPARC to influence pathways involved in extracell...
TMPH-00659	FlgM Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar ...
TMPH-01379	GSN Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into fila...
TMPH-02111	SRP72 Protein, Human, Recombinant (GST)	Human	E. coli
	Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might intera...
TMPH-00249	Bovine coronavirus (strain Quebec) Nucleoprotein/NP Protein (His)	BCoV	E. coli
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
TMPH-00250	Bovine coronavirus (strain F15) Nucleoprotein/NP Protein (His)	BCoV	HEK293 Cells
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
TMPH-03226	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)	RABV	E. coli
	Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates...
TMPH-00194	Bat coronavirus HKU3 Nucleoprotein/NP Protein (His)	BtCoV	Baculovirus Insect Cells
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
TMPH-00666	FtsZ Protein, E. coli O157:H7, Recombinant (His & Myc)	E. coli	E. coli
	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun...
TMPH-00248	Bovine coronavirus (strain Mebus) Nucleoprotein/NP Protein (His)	BCoV	E. coli
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
TMPH-00138	IBV (strain KB8523) Nucleoprotein/NP Protein (His)	IBV	HEK293 Cells
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
TMPH-00141	IBV (strain D1466) Nucleoprotein/NP Protein (His)	IBV	E. coli
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an impo...
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