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カタログ番号 | 製品名 | 別名 | ターゲット |
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T40857 | Calcium ionophore II | Calcium ionophore II,N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide | Others |
Calcium ionophore II (N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide) is a lipophilic ionophore that can be used in preparing calcium ion-selective electrode. | |||
T3956 | Sodium ionophore III | ETH2120 | Sodium Channel |
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood. | |||
T21663 | Calcium Ionophore I | ||
T6170 | Elesclomol | STA-4783 | Apoptosis , HSP , Reactive Oxygen Species |
Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-medi... | |||
T82727 | Chromoionophore XIII | SNARF-DE | |
Chromoionophore XIII (SNARF-DE), functioning as a pH sensor, is excitable with red light. Its unique properties impart lipophilicity and prevent the lactonization of the dye in apolar environments, ensuring the molecule'... | |||
T12593 | Pyrithione | 1-hydroxyl-1H-pyridine-2-thione | Others |
Pyrithione (1-hydroxyl-1H-pyridine-2-thione) is a transition metal complex, a zinc ionophore, that causes elevated zinc levels in mammalian cells. Pyrithione has potent bactericidal and antifungal activity. | |||
T22946 | LY255283 | LY 255283 | Leukotriene Receptor |
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A2318... | |||
T31638 | Enniatin C | ||
Enniatin C is an ionophore that can bind ammonium. | |||
T34992 | UK 58852 | UK58852 | |
UK 58852 is a polyether ionophore. | |||
T30147 | AS 701 | AS-701,AS701 | |
AS-701 is a Li+ selective ionophore in the therapy of manic-depressive illness. | |||
T26474 | A28086B | A 28086B,A-28086B | |
A28086B is an ionophore antibiotic. | |||
T32538 | Laidlomycin butyrate | ||
Laidlomycin butyrate is a ionophore with enhanced intraruminal activity. | |||
T27504 | GV-196771 | ||
GV-196771 selectively antagonize the glycine-binding site of the NMDA ionophore. | |||
T10137 | 4-Bromo A23187 | 4-Bromo A23187 | Others |
4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells. | |||
T26421 | A 55453 | A55453,A-55453 | |
A 55453 is a radiated ionophore used as a reversibl, high-affinity alpha 1-adrenergic receptor probe. | |||
T34492 | Salinazid | Nilazid,Salicylaldehyde isonicotinoyl hydrazone,Salizid,Salizide,Nupasal,SIH1 | Others |
Salinazid (Salicylaldehyde isonicotinoyl hydrazone) is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to clioquinol. | |||
T16323 | Nigericin | Others | |
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin can be an NLRP3 activator that causes the release of I... | |||
T37284 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE | ||
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore... | |||
T37124 | 1,3-Dipalmitoleoyl-rac-glycerol | ||
1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC50s = 4.45 and 9,326.5 μM, respectivel... | |||
T37650 | 5(S),15(S)-DiHETE | ||
5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophi... | |||
T21681 | AACOCF3 | Arachidonyl trifluoromethyl ketone,Arachidonyltrifluoromethane | Phospholipase |
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid. It is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By... | |||
T37649 | 5(S),12(S)-DiHETE | ||
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be prod... | |||
T35731 | Deethylindanomycin | ||
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of... | |||
T75656 | Calcimycin hemimagnesium | ||
Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium l... | |||
T35541 | Lipoxygenin | ||
Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-de... | |||
T37492 | 11-trans Leukotriene C4 | 11-trans Leukotriene C4 | |
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative... | |||
T37606 | Resolvin D5 | 7(S),17(S)-diHDHA | |
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory respons... | |||
T35509 | (±)14-HDHA | ||
(±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. DHA is metabolized to 14(S)-HDHA by human platelet... | |||
T37052 | Tetranactin | ||
Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold g... | |||
T37331 | Pyrrophenone | ||
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of pros... | |||
T14205 | AM679 | Others | |
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition ... | |||
T83773 | Prostaglandin E2 Inhibitor 3 | PGE2 Inhibitor 3 | |
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 µM), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T15717 | Lasalocid | Lasalocid-A,Antibiotic X-537A,Ionophore X-537A | Antibacterial |
Lasalocid (Lasalocid-A) is an ion carrier antibiotic produced by Streptomyces, which has antimicrobial and parasitic properties and is often added to feed. | |||
T15716 | Lasalocid sodium | Ionophore X-537A sodium,Antibiotic X-537A sodium,Lasalocid-A sodium | Antibacterial , Antibiotic , Autophagy |
Lasalocid sodium (Lasalocid-A sodium) is a cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. Lasalocid sodium is used as a co... | |||
T11665 | Ionomycin calcium | SQ23377 calcium | Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC |
T10662L | Calcimycin | Antibiotic A-23187,A-23187 | Apoptosis , Antibacterial , Antibiotic , Autophagy , Antifungal |
T0906 | Salinomycin | Procoxacin | Wnt/beta-catenin , Antibacterial |
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria. It acts as a potent inhibitor of Wnt/β-catenin signaling, blocking Wnt-induced LRP6 phosph... | |||
T7285 | Ionomycin | Calcium Channel | |
Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as ... | |||
T34611 | Semduramicin | UK 61,689,Aviax,UK-61,689,UK61,689 | |
Semduramicin is a carboxylic acid ionophore for management of chicken coccidiosis. | |||
T10662 | Calcimycin hemicalcium salt | Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt | Others |
Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration. | |||
T34611L | Semduramicin sodium | UK-61,689-2,UK 61,689-2,UK 61689-2,UK-61689-2,UK61689-2 | |
Semduramicin sodium is a carboxylic acid ionophore for management of chicken coccidiosis. | |||
TN5939 | Glutinone | 5-Glutinen-3-one | |
Glutinone (IC50=24 microM) shows a significant effect on thromboxane B2 (TXB2)-release induced by calcium ionophore in human platelets. | |||
TQ0215 | Salinomycin sodium salt | Sodium salinomycin,Salinomycin sodium | Apoptosis , Wnt/beta-catenin , Antibacterial , Antibiotic , Autophagy |
TN4584 | Morolic acid | IL Receptor , COX , HIV Protease | |
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediat... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-04672 | Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... | |||
TMPY-00086 | Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His) | Rat | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... | |||
TMPY-03181 | Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His) | Human | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... |