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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1148 | Isopsoralenoside | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Antibacterial | |
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects. | |||
T5751 | Tigogenin | Others | |
Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis. | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T13589 | Caesappanin C | Others | |
Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. | |||
T5S2129 | Sciadopitysin | TNF , NF-κB | |
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o... | |||
T7190 | Actein | Apoptosis , Akt , JNK , Autophagy | |
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in... | |||
TN3754 | Dalbergiphenol | Others | |
Dalbergiphenol shows antiosteoporotic activity, dalbergiphenol treatment can effectively prevent OVX-induced increase in bone loss and decrease in bone strength possibly by increasing osteoblastic activities and by decre... | |||
TN3753 | Dalbergioidin | Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad | |
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator or... | |||
TN2533 | 1-Hydroxy-2,3,4,7-tetramethoxyxanthone | 5-HT Receptor | |
1-Hydroxy-2,3,4,7-tetramethoxy-xanthone has vasodilatory action, it can cause vasodilation in the coronary artery pre-contracted with 1uM 5-hydroxytryptamine (5-HT), with the EC 50 value of 6.6±1.4 uM. 1-Hydroxy-2,3,4,7-... | |||
TN4094 | Gallocatechin gallate | IL Receptor , NF-κB , ROS , MAPK , PPAR , Fatty Acid Synthase | |
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabeti... | |||
TN2534 | 1-Hydroxy-2,3,5-trimethoxyxanthone | IκB/IKK , Calcium Channel , NOS , 5-HT Receptor , COX | |
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type vo... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPH-02434 | PTH Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | E. coli |
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Cynomolgus,... | |||
TMPH-03348 | PTH Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Rat, Recomb... | |||
TMPJ-01042 | Osteocrin Protein, Human, Recombinant (His) | Human | E. coli |
Osteocrin is a secreted protein which is primarily expressed in bone and muscle. It is synthesized as a proprotein that undergoes proteolytic processing to generate a mature 50 amino acid C-terminal active peptide.Human ... | |||
TMPJ-00437 | Fetuin A Protein, Macaca mulatta, Recombinant (His) | Macaca mulatta | HEK293 Cells |
Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocyt... |