|
T9865 |
Almonertinib mesylate
|
|
EGFR
|
|
Almonertinib mesylate is an irreversible inhibitor of EGFR tyrosine kinase with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate can be used in the non-small cell lung cancer st... |
|
T60076 |
Oritinib
|
SH-1028 |
EGFR
|
|
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ... |
|
T1223 |
Ceftriaxone sodium hydrate
|
Ceftriaxone Sodium Trihydrate,Ceftriaxone disodium hemiheptahydrate,Ceftriaxone sodium |
Others
,
Antibacterial
,
Antibiotic
|
|
Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. |
|
T3061 |
Lorlatinib
|
PF-6463922,PF-06463922,Loratinib |
Apoptosis
,
Tyrosine Kinases
,
ROS
,
ALK
,
ROS Kinase
|
|
Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. |
|
T1599 |
Ibandronic acid
|
Bonviva,Bondronat,Boniva |
Others
,
HBV
|
|
Ibandronic acid (Bonviva) is a third-generation amino-bisphosphonate with anti-resorptive and anti-hypercalcemic activities. |
|
T0138 |
Cefpiramide acid
|
Cefpiramidum,Cefpiramido |
Antibacterial
|
|
Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic. |
|
T7120 |
Cefetamet pivoxil hydrochloride
|
Ro 15-8075 |
Antibacterial
,
Antibiotic
|
|
Cefetamet pivoxil hydrochloride (Ro 15-8075) is a third generation cephalosporin antibiotic with oral activity. |
|
T0198 |
Ceftiofur sodium
|
Naxcel,Sodium ceftiofur |
Antibacterial
,
Antibiotic
|
|
Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine. |
|
T7839 |
Lasofoxifene Tartrate
|
CP-336156 |
Estrogen Receptor/ERR
|
|
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator. |
|
T0127 |
Glimepiride
|
Glimperide,HOE-490 |
Potassium Channel
|
|
Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity. |
|
T0911 |
Cefotaxime sodium
|
Cefotaxim sodium salt,Cefotaxime sodium salt,Cefotaxim (sodium salt),HR-756 (sodium salt) |
Antibacterial
,
Antibiotic
|
|
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to b... |
|
T9073 |
SRS16-86
|
|
Ferroptosis
|
|
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis. |
|
T1405 |
Cefditoren pivoxil
|
ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl |
Antibacterial
,
Antibiotic
|
|
Cefditoren pivoxil (ME 1207) is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. |
|
T5024 |
Cefotiam Hexetil Hydrochloride
|
|
Antibacterial
,
Antibiotic
|
|
Cefotiam Hexetil Hydrochloride is a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. |
|
T6268 |
Ceftiofur hydrochloride
|
Ceftiofur HCl,U-67279A,Excenel hydrochloride |
Antibacterial
,
Antibiotic
|
|
Ceftiofur hydrochloride (U-67279A) is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. |
|
T4405 |
Ceftibuten dihydrate
|
Sch-39720 dihydrate |
Antibacterial
,
Antibiotic
|
|
Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity. |
|
T4990 |
Cefcapene pivoxil hydrochloride hydrate
|
Cefcapene Pivoxil Hydrochloride |
Antibacterial
,
Antibiotic
|
|
Cefcapene pivoxil hydrochloride hydrate is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil, the es... |
|
T2490 |
Osimertinib
|
AZD-9291,Mereletinib |
EGFR
|
|
Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi... |
|
T16398 |
Opicapone
|
BIA 9-1067 |
Transferase
|
|
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. |
|
T4998L |
Cefpodoxime (free acid)
|
|
Others
|
|
Cefpodoxime (free acid) is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. |
|
T22354 |
Levocetirizine Dihydrochloride
|
Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride |
Histamine Receptor
|
|
Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydro... |
|
T0932 |
Cefixime
|
FK-027,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635 |
Antibacterial
,
Antibiotic
|
|
Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lact... |
|
T15771 |
Lobaplatin
|
D-19466 |
DNA Alkylation
|
|
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a ... |
|
T1451 |
Levofloxacin hydrate
|
Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate |
DNA gyrase
,
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial c... |
|
T0133 |
Cefdinir
|
FK-482,CI-983,PD 134393 |
Glutathione Peroxidase
,
Antibacterial
,
Antibiotic
|
|
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of the ear, sinus, throat and skin. |
|
T4998 |
Cefpodoxime proxetil
|
|
Antibacterial
,
Antibiotic
|
|
Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxi... |
|
T1616 |
Cefotiam hydrochloride
|
Pansporin,SCE-963 hydrochloride,Pansporine,Cefotiam dihydrochloride,Halospor |
Antibacterial
,
Antibiotic
|
|
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicilli... |
|
T21395 |
Finerenone
|
BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862 |
Glucocorticoid Receptor
|
|
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862... |
|
T8747 |
Levofloxacin hydrochloride
|
|
DNA gyrase
,
Topoisomerase
|
|
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh... |
|
T10753 |
Ceftibuten
|
Sch 39720 |
Others
|
|
Ceftibuten is a third-generation cephalosporin antibiotic. |
|
T34348 |
Ro 14-1761
|
Ro-14-1761 |
|
|
Ro 14-1761 is a new third-generation cephalosporin. |
|
T34239 |
R 8605
|
R-8605,R8605 |
|
|
R 8605 is a third-generation retinoid. |
|
T34240 |
R 8923
|
R-8923,R8923 |
|
|
R 8923 is a third-generation retinoid. |
|
T31590 |
E 4441
|
E-4441,E4441 |
|
|
E 4441 is a third-generation difluoroquinolone, which has good activity against G(+) aerobic bacteria and anaerobic bacteria in vitro and in vivo. |
|
T23871 |
Cefuzonam sodium
|
CZON,L-105,Cosmosin,CL 251931 sodium salt,L 105 |
|
|
Cefuzonam sodium is a second-generation cephalosporin antibiotic. It may be effective against Staphylococcus aureus against which third-generation cephalosporins are largely ineffective. |
|
T26238 |
Sumarotene
|
Ro14-9706,Ro-14-9706,Ro 14-9706 |
|
|
Sumarotene, a third-generation retinoid, is used as a topical dermatologic agent for the repair of antikeratinization, photodamage, and antiproliferation. |
|
T4998L2 |
Cefpodoxime sodium
|
R3746,R 3763,R 3746,R-3746,R-3763 |
|
|
Cefpodoxime sodium is a third generation cephalosporin antibiotic agent. It targets gram-positive and gram-negative bacteria, especially those responsible for otitis media and pharyngitis. |
|
T23810 |
BMX-001
|
MnTnBuOE-3-PyP 5+,manganese butoxyethyl pyridyl porphyrin,BMX001,manganese (III) ortho N-butoxyethylpyridylporphyrin |
|
|
BMX-001 is a third-generation, cationic, lipophilic, manganese (Mn), and porphyrin-based mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD). It also has antioxidant and potential chemoprotective ac... |
|
T14030 |
3-Desacetyl Cefotaxime lactone
|
|
Others
|
|
3-Desacetyl Cefotaxime lactone, the active metabolite of Cefotaxime, is derived from its sodium salt form, which is recognized as a third-generation cephalosporin antibiotic. |
|
T38643 |
Cefixime trihydrate
|
CL-284635trihydrate,FR-17027 trihydrate,FK-027trihydrate |
|
|
Cefixime trihydrate (FR-17027 trihydrate) is a potent antibiotic belonging to the third generation of cephalosporins. Its efficacy lies in the treatment of various bacterial infections. |
|
T21386 |
Ceftizoxime Sodium
|
Epocelin,Eposerin,Monosodium Salt, Ceftizoxime,Cefizox,Ceftizoxime sodium salt,Ceftizoxim-natrium |
|
|
Ceftizoxime, a third-generation cephalosporin effective against Gram-negative and Gram-positive bacteria, binds penicillin-binding proteins (PBPs) to inhibit the bacterial cell wall synthesis. It rather resembles cefotax... |
|
T81412 |
Pradofloxacin
|
|
|
|
Pradofloxacin is a third-generation fluoroquinolone antibacterial agent. |
|
T61764 |
Zoledronic acid disodium tetrahydrate
|
|
|
|
Zoledronic Acid (Zoledronate) disodium tetrahydrate is a potent third-generation bisphosphonate (BP), exhibiting strong anti-resorptive activity. It effectively inhibits osteoclast differentiation and apoptosis, while al... |
|
T68570 |
TPI-287
|
|
|
|
TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cyc... |
|
T41106 |
Cefpodoxime proxetil impurity B
|
|
|
|
Cefpodoxime proxetil impurity B is a constituent found in Cefpodoxime proxetil, which is a third-generation cephalosporin. This compound, known as Cefpodoxime Proxetil, is a highly effective oral antibiotic with a broad ... |
|
T38783 |
DOTA-tri(t-butyl ester)
|
|
|
|
DOTA-tri(t-butyl ester) is a versatile compound employed for the synthesis of third-generation (G3) nanoglobular magnetic resonance imaging (MRI) contrast agents. These contrast agents find application in the fields of M... |
|
T67809 |
Simotaxel
|
|
|
|
Simotaxel is a semi-synthetic, orally bioavailable, third-generation taxane derivative and microtubule-stabilizing agent, with potential antineoplastic activity. |
|
T36644 |
Rezivertinib
|
|
|
|
Rezivertinib (BPI-7711) is an orally active, highly selective and irreversible third-generation EGFR tyrosine kinase inhibitor (TKI) with potent activity against both common activation EGFR and resistance T790M mutations... |
|
T38448 |
(Rac)-Finerenone
|
(Rac)-Finerenone,(Rac)-BAY 94-8862 |
|
|
Rac-Finerenone, also known as (Rac)-BAY 94-8862, is the racemate derivative of Finerenone, a selective third-generation nonsteroidal mineralocorticoid receptor antagonist (MR) that is taken orally. With an IC50 value of ... |
|
TP2288 |
Rapalink-1
|
|
Others
|
|
RapaLink-1 is the third-generation mTOR inhibitor exploiting the unique juxtaposition of two drugs (first- and second-generation mTOR kinase inhibitors) -binding pockets to create a bivalent interaction that allows inhib... |
