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T8354 |
Triazavirin
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|
Nucleoside Antimetabolite/Analog
,
Influenza Virus
,
DNA/RNA Synthesis
|
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Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. |
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T23513 |
VU10010
|
VU 10010 |
AChR
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VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors. |
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T1234 |
5,5-Dimethyloxazolidine-2,4-dione
|
Dimethadion,Dimethadione,Dimethyloxazolidinedione |
Calcium Channel
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5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE. |
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T9988 |
Wnt/β-catenin agonist 3
|
|
Wnt/beta-catenin
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Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist. |
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TP1559L |
Ziconotide Acetate (107452-89-1 free base)
|
Prialt,Ziconotide Acetate |
Calcium Channel
|
|
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (107452-89-1 free base) acts by binding to N-type calcium chan... |
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T3280 |
Clodronate disodium tetrahydrate
|
clodronic acid disodium tetrahydrate,Disodium clodronate tetrahydrate,Clastoban,Clodronate disodium |
IL Receptor
,
TNF
|
|
Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification. |
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TP1868 |
Proctolin
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Others
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|
Proctolin is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods. |
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T27400L |
Ganaplacide phosphate
|
Ganaplacide phosphate (1261113-96-5 Free base) |
Others
|
|
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models. |
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T0924 |
Benzocaine
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|
Others
,
MRP
,
Sodium Channel
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Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
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T7115 |
Pymetrozine
|
CGA 215944 |
Antibacterial
|
|
Pymetrozine (CGA 215944) is a Homoptera feeding inhibitor that effectively prevents transmission of the cauliflower mosaic caulimovirus by the aphid species Myzus persicae. |
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T16697 |
Pyronaridine tetraphosphate
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|
Topoisomerase
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|
Pyronaridine tetraphosphate is an orally active, mannitol-containing inhibitor of DNA topoisomerase 2 and erythrocyte cytokine with antimalarial and antitumour activity.Pyronaridine tetraphosphate treats P. falciparum an... |
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T22963 |
McN-A 343
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|
AChR
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McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ... |
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T0166 |
Pancuronium dibromide
|
Pancuronium bromide,Pavulon |
AChR
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|
Pancuronium dibromide (Pavulon), a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide(Pancuronium bromide) blocking neuromuscular transmission is achieved by competing ... |
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T67765 |
MenA-IN-2
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|
Others
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|
MenA-IN-2 is a potent 1, 4-dihydroxy-2-naphthoate isopentadiene transferase (MenA) inhibitor with an IC50 value of 22 µM for MenA and 10 µM for Mycobacterium tuberculosis (Mtb). The continuous transmission of MenA-IN-2 M... |
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T13102 |
TCMDC-135051
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|
Others
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TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transitio... |
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T1065 |
Baclofen
|
Lioresal |
GABA Receptor
|
|
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... |
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T25616 |
Lanepitant 2HCl
|
LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride |
Neurokinin receptor
|
|
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam... |
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T8630 |
Baclofen hydrochloride
|
4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride |
GABA Receptor
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|
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe... |
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T50008 |
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide
|
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide |
Others
|
|
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide (5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide) is a compound of the phenoxy family. It has been shown to have stimulatory effects on the nervous system, including increased neur... |
|
T1092 |
Zolmitriptan
|
311C90,BW-311C90 |
5-HT Receptor
|
|
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and... |
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TP2505L |
LAH4 acetate
|
KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base) |
Antibacterial
|
|
LAH4 acetate is the α-helical structure of the designed amphoteric peptide antibiotic, which is capable of complexing DNA, associating with the cell surface membrane and wrapped in the endosome, which is destroyed with t... |
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T71952 |
DDD01035881
|
|
|
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DDD01035881 is a novel transmission blocker of antimalarials, targeting male gametes. |
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T24450 |
Mephenoxalone
|
Lenetran Lenetran,TAB Lenetranat |
|
|
Mephenoxalone is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission and relaxing skeletal muscles by inhibiting the reflex arc. |
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T69043 |
GJH-166
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|
|
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GJH-166 is an analog of dopamine that has been shown to inhibit adrenergic transmission in canines. |
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T69964 |
Bornaprine
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|
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Bornaprine is an anticholinergic drug used to treat Parkinson's disease due to inhibition of muscarinic or nicotinic transmission. |
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T69165 |
Methiothepin methanesulfonate
|
|
|
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Methiothepin methanesulfonate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein. |
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T31903 |
Galphimine B
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|
|
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Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect. |
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T26230 |
Stilbamidine dihydrochloride
|
NSC 35605,NCI 174 |
|
|
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection. |
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T34458 |
Ryanodol
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Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission. |
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T71531 |
Metamizil hydrochloride
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|
|
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Metamizil hydrochloride is a cholinolytic agent -- an agent that blocks the transmission of excitation from cholinergic nerve fibers -- and an antagonist of the mediator acetylcholine. |
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T6782 |
Benzocaine hydrochloride
|
Benzocaine HCl,Ethyl p-aminobenzoate hydrochloride,Ethyl 4-aminobenzoate hydrochloride |
Sodium Channel
|
|
Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
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T24839 |
Stampidine
|
HI-113,HI 113,HI113 |
|
|
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical... |
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T69439 |
Nicotine tartrate
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|
|
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Nicotine tartrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also importa... |
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TP1471 |
Ziconotide TFA (107452-89-1 free base)
|
Ziconotide TFA |
|
|
Ziconotide TEA acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects. |
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T69804 |
Nicotine monomethiodide
|
|
|
|
Nicotine monomethiodide is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also i... |
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T68289 |
Nicotine hemicitrate
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|
|
|
Nicotine hemicitrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also impo... |
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T68439 |
Nicotine dicitrate
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|
|
|
Nicotine dicitrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also import... |
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TD0005 |
SYBR GREEN II
|
SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade) |
|
|
1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-... |
|
T62410 |
Hydroxyethylamine
|
|
|
|
Hydroxyethylamine (Compd VII) is a SARS-CoV-2 3CLpro inhibitor with an IC50 of ~10 μM in a transmission assay. hydroxyethylamine exhibits significant antiviral effects. |
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T76568 |
Aminopeptidase N Ligand (CD13) NGR peptide
|
|
|
|
Aminopeptidase N Ligand (CD13) NGR peptide, a polypeptide that targets CD13, functions as a carrier for mediating intracellular transmission and is commonly utilized in cancer research [1] [2]. |
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TP2077 |
α-Bungarotoxin
|
|
|
|
Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β... |
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T60950 |
Pirepemat fumarate
|
|
|
|
Pirepemat (IRL752) fumarate can be used in Parkinson's disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2]. |
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TP1032 |
Transdermal Peptide TFA (918629-48-8 free base)
|
Transdermal Peptide TFA,TD 1 (peptide) (TFA) |
|
|
Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+/K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmissi... |
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T69627 |
Dapivirine HCl
|
|
|
|
Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promi... |
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T69012 |
Cinnarizine clofibrate
|
|
|
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Cinnarizine clofibrate is a calcium channel protein inhibitor as well as an antihistamine channel blocker. The compound is a drug derivative of piperazine. Cinnarizine is used for the control of vomiting due to motion si... |
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T68811 |
Trimetaphan camsilate
|
|
|
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Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathe... |
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T68836 |
ADS-J1
|
|
|
|
ADS-J1 is an HIV-1 entry inhibitor that potently inhibits seminal amyloid fibrillization and block fibril-mediated enhancement of viral infection. Semen-derived amyloid fibrils, comprising SEVI (semen-derived enhancer of... |
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T70075 |
KDS2010 mesylate
|
|
|
|
KDS2010 is a potent, highly selective, and reversible MAO-B inhibitor which shows 12,500-fold selectivity over MAO-A. KDS2010 overcomes the disadvantages of the irreversible MAO-B inhibitor and significantly attenuates i... |
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T81511 |
Peptide F, bovine
|
|
|
|
Peptide F (bovine) is a bovine-derived proenkephalin peptide F identified in the brain and adrenal medulla. It is implicated in the enkephalinergic system's role in pain transmission [1]. |
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T75710 |
Ziconotide TFA
|
|
|
|
Ziconotide TFA (SNX-111 TFA), a peptide-based, potent, and selective N-type calcium channels antagonist, effectively reduces synaptic transmission and is utilized in chronic pain research [1]. |
