検索結果

Search Results for " variants "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T6797	Telaglenastat	CB 839,CB839,CB-839	transporter , Glutaminase , Autophagy
	Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.		transporter , Glutaminase , Autophagy
T22324	Ensartinib hydrochloride	Ensartinib dihydrochloride,X-396 dihydrochloride	Others , Trk receptor , c-Met/HGFR , ALK
	Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both...		Others , Trk receptor , c-Met/HGFR , ALK
T16813	RX-3117	fluorocyclopentenylcytosine,TV-1360	Nucleoside Antimetabolite/Analog
	RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.		Nucleoside Antimetabolite/Analog
T4618	BGG463	K 0859	Bcr-Abl , CDK
	BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.		Bcr-Abl , CDK
TP1344	Luciferase		Others
	Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac...		Others
T4547	Grazoprevir	MK-5172	HCV Protease , SARS-CoV
	Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ...		HCV Protease , SARS-CoV
T15573	Inarigivir soproxil	SB9200	HCV Protease
	Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ...		HCV Protease
T7502	PF 05089771 tosylate		Sodium Channel
	PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8...		Sodium Channel
T3550	X-376	Ensartinib,X-396	c-Met/HGFR , ALK
	X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inh...		c-Met/HGFR , ALK
T12065	Grazoprevir sodium salt	MK-5172 (sodium salt)	Others
	Grazoprevir sodium salt is a selective Hepatitis C virus NS3/4a protease inhibitor with broad activity across genotypes and resistant variants.		Others
T39650	Tadnersen	IONIS-C9Rx,BIIB078
	Tadnersen (BIIB078) is an antisense oligonucleotide (ASO) designed for the selective targeting of C9ORF72 transcript variants 1 and 3, specifically those carrying the expansion.
T10141	4'-Ethynyl-2'-deoxyadenosine		Others
	4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a nucleoside reverse transcriptase (RT) inhibitor. It is potent against drug-resistant HIV variants (EC50: 98 nM in MT-4 cells for anti-HIV-1 activity).		Others
T27201	DPC-082	DPC 082
	DPC-082 is a reverse transcriptase inhibitor. DPC-082 exhibits low-nanomolar potency toward wild-type virus, L100I and K103N single-mutation variants, and multiplies amino acid-substituted HIV type 1 mutants.
T21456	Grazoprevir hydrate	Grazoprevir,MK5172,MK 5172,MK-5172
	Grazoprevir, a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets, has good activity against a range of hepatitis C virus genotype variants, including some that are resistant to ...
T79612	Tyrosine kinase-IN-6		c-Met/HGFR
	Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic effects [1].		c-Met/HGFR
T62068	Chitin synthase inhibitor 1
	Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with IC50 of 0.12 mM. Chitin synthase inhibitor 1 potently inhibits drug-resistant fungi variants.
T26574	AG-7404	AG 7404
	AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 μM. AG-7404 was fully active against V-073-resistant variants with E...
T69536	MMT5-14
	MMT5-14 is a SARS-CoV-2 inhibitor. MMT5-14 showed 2- to 7-fold higher antiviral activity in four variants of SARS-CoV-2. By reducing premature hydrolysis in hamsters, MMT5-14 increased the prodrug concentration by 200- t...
T39983	SPR206 acetate
	SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetat...
T72265	Eltrombopag methyl ester
	Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
T74762	Influenza A virus-IN-8
	Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and functions as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability. It has IC50 values of 6.7 nM for ...
T79344	CDD-1819		SARS-CoV
	CDD-1819, a non-covalent and non-peptide compound, serves as a potent SARS-CoV-2 Mpro inhibitor, exhibiting a K i value of 5 nM. It also effectively inhibits the Mpro variants ΔP168, A173V, and ΔP168/A173V [1].		SARS-CoV
T76900	Adintrevimab
	Adintrevimab (ADG 20), a human IgG1 monoclonal antibody, targets SARS-CoV (SARS-CoV) and demonstrates inhibition against SARS-CoV-2 variants as well as other SARS-like coronaviruses with pandemic potential [1].
T78252	Bebtelovimab	LY-3853113,LY-COV1404	SARS-CoV
	Bebtelovimab is a humanized IgG1-λ2 antibody specifically targeting SARS-CoV-2 and has demonstrated potent neutralization against its variants, exhibiting mild-to-moderate efficacy in inhibiting COVID-19 [1] [2].		SARS-CoV
T74617	HDAC6-IN-8		HDAC
	Compound 12C, modified by altering cap groups, exhibits broad-spectrum enzyme inhibitory activity, as demonstrated in enzyme inhibition assays. Conversely, compounds 9m and 9q display a predilection towards HDAC6 inhibit...		HDAC
T77137	Rafivirumab
	Rafivirumab (CR57) is a monoclonal antibody designed for rabies prophylaxis, exhibiting neutralizing efficacy against a wide range of rabies virus (RABV) variants. It is also utilized in cocktail research studies [1] [2]...
T76846	Casirivimab
	Casirivimab (REGN10933), a human monoclonal antibody targeting the SARS-CoV-2 virus responsible for COVID-19, demonstrates reduced efficacy against emerging variants. When combined with Imdevimab, it significantly lowers...
T79345	CDD-1733		SARS-CoV
	CDD-1733 is a potent, non-covalent, and non-peptide inhibitor of the SARS-CoV-2 main protease (Mpro) with an inhibition constant (K i) of 12 nM. It effectively inhibits Mpro variants including ΔP168, A173V, and the combi...		SARS-CoV
T76904	Amubarvimab
	Amubarvimab (BRII-196), a human IgG1 monoclonal antibody (mAb), targets non-competing epitopes on the receptor binding domain (RBD) of the spike protein, exhibiting a dissociation constant (K D) of 5.88 nM. It has demons...
T73846	PF-06456384 trihydrochloride
	PF-06447475 trihydrochloride is a potent, selective LRRK2 kinase inhibitor that demonstrates excellent brain penetration, exhibiting IC50 values of 3 nM for wild-type LRRK2 and 11 nM for G2019S LRRK2 variants. It holds p...
T77121	Pozelimab
	Pozelimab (REGN3918), a fully human IgG4 monoclonal antibody, is designed to target and bind with high affinity to both C5 and its variants, effectively inhibiting complement-mediated hemolysis. It holds potential for re...
T78713	SARS-CoV-2-IN-40		SARS-CoV
	SARS-CoV-2-IN-40 (Compound 19), a SARS-CoV-2 inhibitor, effectively suppresses the infection of Calu3 lung cells by the BA.1 and BA.5 variants, exhibiting half-maximal inhibitory concentrations (IC50s) of 100 nM and 160 ...		SARS-CoV
T79346	CDD-1845		SARS-CoV
	CDD-1845, a non-covalent, non-peptide inhibitor, exhibits potent inhibition of SARS-CoV-2 M^pro with a K_i value of 3 nM. Additionally, CDD-1845 is effective against M^pro variants ΔP168, A173V, and the combined ΔP168/A1...		SARS-CoV
T71113	Minnelide free acid
	Minnelide is an effective therapy against pancreatic cancer. Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variant...
T26581	AIC-292
	AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained ...
T40097	RET-IN-4
	RET-IN-4 is a highly effective and specific RET inhibitor that can be administered orally. It demonstrates remarkable potency, with IC50 values of 1.29 nM, 1.97 nM, and 0.99 nM for inhibiting RET variants including RET (...
T39309	Telaglenastat hydrochloride	CB-839 hydrochloride
	Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) a...
T76847	Imdevimab
	Imdevimab (REGN10987), a human monoclonal antibody designed to neutralize the SARS-CoV-2 virus responsible for COVID-19, demonstrates reduced efficacy against emerging COVID-19 variants. When combined with Casirivimab, i...
T78867	WU-04		SARS-CoV
	WU-04 is a non-covalent inhibitor targeting the 3CLpro protein of SARS-CoV-2, demonstrating high inhibitory effects on 3CLpro from six SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda, and Omicron) as well as two o...		SARS-CoV
T72718	SARS-CoV-2-IN-36
	SARS-CoV-2-IN-36 is a potent inhibitor of SARS-CoV-2 Mpro (SARS-CoV), demonstrating an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. This compound exhibits antiviral activity against SARS-CoV-2 variants UC-107...
T72911	11β-HSD1-IN-9
	11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively. It exhibits competitive interaction with rat 11β-HSD1. This compound holds potent...
T79313	BI 7446		STING
	BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants in cells, thus inducing tumor-specific immune-mediated tumor ...		STING
T72289	Type II TRK inhibitor 1		Trk receptor
	Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) fusion protein variants as well as the wild type. It demonstrates notable antiproliferative effects on Ba/F3 cells expres...		Trk receptor
T63077	Chitin synthase inhibitor 12
	Chitin synthase inhibitor 12, a Chitin synthase (CHS) inhibitor, showed excellent CHS inhibition (IC50: 0.16 mM). Chitin synthase inhibitor 12 is also a broad-spectrum antifungal agent resistant to resistant fungal varia...
T63811	EPI-7170
	EPI-7170 is a ralaniten analogue and a potent antagonist of the androgen receptor N-terminal structural domain, blocking the transcriptional activity of the full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170...
T78765	SARS-CoV-2-IN-51		SARS-CoV
	SARS-CoV-2-IN-51 (S-10), a lead compound for Omicron fusion inhibition, demonstrates potent activity against Omicron and other SARS-CoV-2 variants, with EC50 values ranging from 0.82-5.45 μM. It functions by directly int...		SARS-CoV
T79420	FLT3-IN-22
	FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. This compound displays significant antiproliferative effects against MV4-11 ...
T76849	Bamlanivimab
	Bamlanivimab, an Anti-Human SARS-CoV-2 monoclonal antibody (mAb), was the first of its kind to receive Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) in November 2020 for COVID-19 trea...
T75090	STING agonist-22
	STING Agonist-22 (CF501) is a potent non-nucleotide STING agonist that functions as an adjuvant by activating STING to induce the type I interferon (IFN-I) response and the production of proinflammatory cytokines. It enh...
T74326	αGalCer-RBD
	αGalCer-RBD, a conjugate of the potent invariant natural killer T cell (iNKT) agonist α-Galactosylceramide (αGalCer) and the receptor-binding domain (RBD), serves as a self-adjuvanting lipoprotein that exhibits strong po...

Compounds

Telaglenastat

T6797

Synonym: CB 839,CB839,CB-839

Target: transporter, Glutaminase, Autophagy

Ensartinib hydrochloride

T22324

Synonym: Ensartinib dihydrochloride,X-396 dihydrochloride

Target: Others, Trk receptor, c-Met/HGFR, ALK

RX-3117

T16813

Synonym: fluorocyclopentenylcytosine,TV-1360

Target: Nucleoside Antimetabolite/Analog

Target: HCV Protease, SARS-CoV

Target: Sodium Channel

X-376

T3550

Synonym: Ensartinib,X-396

Target: c-Met/HGFR, ALK

Grazoprevir sodium salt

T12065

Synonym: MK-5172 (sodium salt)

Target: Others

Tadnersen

T39650

Synonym: IONIS-C9Rx,BIIB078

Target:

4'-Ethynyl-2'-deoxyadenosine

Synonym: Grazoprevir,MK5172,MK 5172,MK-5172

Chitin synthase inhibitor 1

Eltrombopag methyl ester

T72265

Synonym:

Target:

Influenza A virus-IN-8

Synonym: LY-3853113,LY-COV1404

PF-06456384 trihydrochloride

Telaglenastat hydrochloride

T39309

Synonym: CB-839 hydrochloride

Type II TRK inhibitor 1

T72289

Synonym:

Target: Trk receptor

Chitin synthase inhibitor 12

カタログ番号	製品名	別名	ターゲット
TQ0209	Ailanthone	Δ13-Dehydrochaparrinone	Androgen Receptor
	Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR splice variants (IC50: 309 nM).		Androgen Receptor
TN3809	Dehydrojuncusol		HCV Protease
	Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patie...		HCV Protease

天然物製品

Ailanthone

TQ0209

Synonym: Δ13-Dehydrochaparrinone

Target: Androgen Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00745	IFN-alpha 2a/IFNA2 Protein, Human, Recombinant	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ...
TMPJ-00746	IFN-alpha 2b/IFNA2 Protein, Human, Recombinant	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ...
TMPY-02580	Histone H1 Protein, Human, Recombinant (His)	Human	E. coli
	H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His)	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ...
TMPY-03407	NQO1 Protein, Human, Recombinant (His)	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-02700	BCL2 Protein, Human, Recombinant (His)	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-06623	CB2/CNR2 Protein, Human, Recombinant	Human	HEK293 Cells
	Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the...
TMPY-03448	AARSD1 Protein, Human, Recombinant (His)	Human	E. coli
	AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcri...
TMPJ-00747	IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant	Mouse	E. coli
	At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a c...
TMPY-03049	GALNT10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 g...
TMPY-05321	CYP3A4 Protein, Human, Recombinant (His)	Human	E. coli
	CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-dr...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His)	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPJ-00697	NOL3 Protein, Human, Recombinant (GST)	Human	E. coli
	Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPY-02581	STAT4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f...
TMPJ-00695	CuTA Protein, Human, Recombinant (His)	Human	E. coli
	Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a bro...
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA...
TMPK-00705	MASP2 Protein, Human, Recombinant (His)	Human	E. coli
	The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As...
TMPJ-00119	IL-22RA2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. I...
TMPJ-01352	THSD1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thrombospondin Type-1 Domain-Containing Protein 1 (THSD1) is a single-pass type I membrane protein. THSD1 contains a signal peptide and one TSP type-1 domain that is found in thrombospondin. THSD1 is a good novel candida...
TMPY-01122	CGB5 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiati...
TMPK-01146	LGMN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in th...
TMPJ-00900	TGM2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monom...
TMPK-00519	LILRA6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic...
TMPY-03982	CGB5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiati...
TMPY-03598	EPDR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EPDR1 is a member of the ependymin family. EPDR1 is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. It may play a role in calcium-dependent c...
TMPY-03842	PRNP/Prion Protein Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamen...
TMPK-00775	PRNP/Prion Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of b...
TMPJ-00525	LGALS14 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Galectin-14 is a member of the Galectin family of carbohydrate binding proteins. The members of Galectin family contain one or two carbohydrate recognition domains, which can bind β-Galactoside. LGALS14 is expressed intr...
TMPK-00928	VLDLR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, stra...
TMPJ-00017	GNRH2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-...
TMPK-01046	LILRA6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic...
TMPK-01047	LILRA6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic...
TMPK-00976	AMHRII Protein, Human, Recombinant	Human	HEK293 Cells
	The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women under...
TMPY-03506	VILIP1 Protein, Human, Recombinant	Human	E. coli
	VILIP-1, also known as VSNL1, is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervou...
TMPK-00737	EVA-1/MPZL2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli...
TMPK-00738	EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli...
TMPY-03504	CBFB Protein, Human, Recombinant (His)	Human	E. coli
	CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os...
TMPY-03412	GGCT Protein, Human, Recombinant (His)	Human	E. coli
	GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in ...
TMPY-03510	Cbl-c Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C...
TMPJ-00030	IL-1F10 Protein, Human, Recombinant	Human	E. coli
	Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate immune responses. IL-1F10 was expressed in fetal skin, spleen ...
TMPY-03502	PAX8 Protein, Human, Recombinant (His)	Human	E. coli
	PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 i...
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPK-00977	AMHRII Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women under...
TMPY-03400	DCBLD1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-termina...
TMPY-03497	AKR1C2 Protein, Human, Recombinant (His)	Human	E. coli
	AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using ...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPY-03496	EBAG9 Protein, Human, Recombinant (His)	Human	E. coli
	RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen ...
TMPY-03434	BMF Protein, Human, Recombinant (His)	Human	E. coli
	BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF...
------------------------ More ------------------------

IFN-alpha 2a/IFNA2 Protein, Human, Recombinant

TMPJ-00745

Species: Human

Expression System: E. coli

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

TMPJ-00746

Species: Human

Expression System: E. coli

Histone H1 Protein, Human, Recombinant (His)

TMPY-02580

Species: Human

Expression System: E. coli

PRSS3 Protein, Human, Recombinant (His)

TMPY-01897

Species: Human

Expression System: HEK293 Cells

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

NQO1 Protein, Human, Recombinant (His)

TMPY-03407

Species: Human

Expression System: E. coli

VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: HEK293 Cells

BCL2 Protein, Human, Recombinant (His)

TMPY-02700

Species: Human

Expression System: E. coli

CB2/CNR2 Protein, Human, Recombinant

TMPY-06623

Species: Human

Expression System: HEK293 Cells

AARSD1 Protein, Human, Recombinant (His)

TMPY-03448

Species: Human

Expression System: E. coli

IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant

TMPJ-00747

Species: Mouse

Expression System: E. coli

GALNT10 Protein, Human, Recombinant (His)

TMPY-03049

Species: Human

Expression System: HEK293 Cells

CYP3A4 Protein, Human, Recombinant (His)

TMPY-05321

Species: Human

Expression System: E. coli

Serpin A1 Protein, Human, Recombinant (aa 25-418, His)

TMPJ-00505

Species: Human

Expression System: HEK293 Cells

NOL3 Protein, Human, Recombinant (GST)

TMPJ-00697

Species: Human

Expression System: E. coli

STAT4 Protein, Human, Recombinant (His)

TMPY-02581

Species: Human

Expression System: Baculovirus Insect Cells

CuTA Protein, Human, Recombinant (His)

TMPJ-00695

Species: Human

Expression System: E. coli

IL-17Rc Protein, Human, Recombinant (hFc)

TMPK-00703

Species: Human

Expression System: HEK293 Cells

MASP2 Protein, Human, Recombinant (His)

TMPK-00705

Species: Human

Expression System: E. coli

IL-22RA2 Protein, Human, Recombinant (hFc)

TMPJ-00119

Species: Human

Expression System: HEK293 Cells

THSD1 Protein, Human, Recombinant (His)

TMPJ-01352

Species: Human

Expression System: HEK293 Cells

CGB5 Protein, Human, Recombinant (mFc)

TMPY-01122

Species: Human

Expression System: HEK293 Cells

LGMN Protein, Human, Recombinant (His)

TMPK-01146

Species: Human

Expression System: HEK293 Cells

TGM2 Protein, Mouse, Recombinant (His)

TMPJ-00900

Species: Mouse

Expression System: HEK293 Cells

LILRA6 Protein, Cynomolgus, Recombinant (His)

TMPK-00519

Species: Cynomolgus

Expression System: HEK293 Cells

CGB5 Protein, Human, Recombinant (His)

TMPY-03982

Species: Human

Expression System: HEK293 Cells

EPDR1 Protein, Human, Recombinant (His)

TMPY-03598

Species: Human

Expression System: HEK293 Cells

PRNP/Prion Protein Protein, Human, Recombinant (hFc)

TMPY-03842

Species: Human

Expression System: HEK293 Cells

PRNP/Prion Protein, Mouse, Recombinant (hFc)

TMPK-00775

Species: Mouse

Expression System: HEK293 Cells

LGALS14 Protein, Human, Recombinant (His)

TMPJ-00525

Species: Human

Expression System: HEK293 Cells

VLDLR Protein, Mouse, Recombinant (His)

TMPK-00928

Species: Mouse

Expression System: HEK293 Cells

GNRH2 Protein, Human, Recombinant (His)

TMPJ-00017

Species: Human

Expression System: HEK293 Cells

LILRA6 Protein, Human, Recombinant (His & Avi)

TMPK-01046

Species: Human

Expression System: HEK293 Cells

LILRA6 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01047

Species: Human

Expression System: HEK293 Cells

AMHRII Protein, Human, Recombinant

TMPK-00976

Species: Human

Expression System: HEK293 Cells

VILIP1 Protein, Human, Recombinant

TMPY-03506

Species: Human

Expression System: E. coli

EVA-1/MPZL2 Protein, Human, Recombinant (hFc)

TMPK-00737

Species: Human

Expression System: HEK293 Cells

EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc)

TMPK-00738

Species: Mouse

Expression System: HEK293 Cells

CBFB Protein, Human, Recombinant (His)

TMPY-03504

Species: Human

Expression System: E. coli

GGCT Protein, Human, Recombinant (His)

TMPY-03412

Species: Human

Expression System: E. coli

Cbl-c Protein, Human, Recombinant (His & GST)

TMPY-03510

Species: Human

Expression System: Baculovirus Insect Cells

IL-1F10 Protein, Human, Recombinant

TMPJ-00030

Species: Human

Expression System: E. coli

PAX8 Protein, Human, Recombinant (His)

TMPY-03502

Species: Human

Expression System: E. coli

Serpin A1e Protein, Mouse, Recombinant (His)

TMPJ-01069

Species: Mouse

Expression System: HEK293 Cells

AMHRII Protein, Human, Recombinant (hFc)

TMPK-00977

Species: Human

Expression System: HEK293 Cells

DCBLD1 Protein, Human, Recombinant (His)

TMPY-03400

Species: Human

Expression System: HEK293 Cells

AKR1C2 Protein, Human, Recombinant (His)

TMPY-03497

Species: Human

Expression System: E. coli

EMMPRIN/CD147 Protein, Human, Recombinant (His)

TMPJ-00160

Species: Human

Expression System: HEK293 Cells

EBAG9 Protein, Human, Recombinant (His)

TMPY-03496

Species: Human

Expression System: E. coli

BMF Protein, Human, Recombinant (His)

TMPY-03434

Species: Human

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L6610	Anti-infective Natural Product Library		1060 compounds
	A unique collection of 1060 species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-infective Natural Product Library

L6610

Compounds: 1060