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カタログ番号 | 製品名 | 別名 | ターゲット |
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T12597 | 5-HT2 antagonist 1 | 5-HT Receptor | |
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity. | |||
T36949 | Niaprazine | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff... | |||
T15270 | Fananserin | RP 62203 | Dopamine Receptor , 5-HT Receptor |
Fananserin is an orally bioavailable and selective antagonist of the 5-HT2 receptor (Ki: 0.37 nM for the rat 5-HT2A receptor). It also is an antagonist of dopamine D4 receptor (Ki: 2.93 nM for the human dopamine D4 recep... | |||
T0137 | Mirtazapine | 6-Azamianserin,Org3770 | Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor |
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h... | |||
T14968 | Cinanserin hydrochloride | SQ 10643 | Influenza Virus , 5-HT Receptor |
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. | |||
T79804 | 5-HT2 agonist-1 | 5-HT Receptor | |
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaini... | |||
T4369 | SCH-23390 hydrochloride | R-(+)-SCH23390 hydrochloride | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). | |||
T79805 | 5-HT2 agonist-1 free base | 5-HT Receptor | |
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression... | |||
T1567 | Olanzapine | LY170053 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR |
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. | |||
T22904 | L-745870 trihydrochloride | L-745,870 trihydrochloride | Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor |
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. | |||
T12865 | SCH-23390 maleate | R-(+)-SCH-23390 maleate | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
T5389 | Volinanserin | M 100907,MDL100907 | 5-HT Receptor |
Volinanserin (MDL100907) (MDL 100907) is a potent and selective antagonist of the serotonin receptor 5-HT2 (Ki: 0.36 nM) and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 adrenergic and sigma recepto... | |||
T23382 | Spiroxatrine | R 5188 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2, and dopamine receptors.Spiroxatrine may be used in the stu... | |||
T22029 | AL 34662 | 5-HT Receptor , Adrenergic Receptor | |
AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a low affinity α-1D adrenergic agonist, with an EC50 of 0.4 μM.... | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T16759 | Ritanserin | R 55667 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. | |||
T22959 | M-Chlorophenylbiguanide hydrochloride | 1-(3-Chlorophenyl)biguanidehydrochloride | 5-HT Receptor |
5-HT3 receptor agonist | |||
T2599 | Pirenperone | 5-HT Receptor | |
Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action. | |||
T22871 | Ipsapirone | 5-HT Receptor | |
Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses. | |||
T2190 | Methiothepin mesylate | Ro 8-6837 mesylate,Metitepine mesylate | Dopamine Receptor , 5-HT Receptor |
Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic. | |||
T68142 | Serazapine | 5-HT Receptor | |
Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders. | |||
T22947 | LY266097 hydrochloride | LY 266097 hydrochloride | 5-HT Receptor |
LY266097 hydrochloride (LY 266097 hydrochloride) is an antagonist of 5-HT2 with pKis of 7.7, 9.8, and 7.6 for human 5-HT2A, 5-HT2B, and 5-HT2C and can be used in studies about depression. | |||
T22689 | CP94253 hydrochloride | CP 94253 hydrochloride | Others , 5-HT Receptor |
CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ... | |||
T24885 | Tiospirone | BMY 13859-1 | Dopamine Receptor , 5-HT Receptor |
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia. | |||
T0351 | Risperidone | Risperidal,R 64 766 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , P-gp |
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. | |||
T3497 | Ocaperidone | Ocaperidona,R79598 | Dopamine Receptor , 5-HT Receptor |
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist. | |||
T68080 | Gevotroline | 5-HT Receptor | |
Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders. | |||
T10872L | CP 96021 | 5-HT Receptor | |
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma. | |||
T12632L | (S)-Mirtazapine | (S)-6-Azamianserin,(S)-Org3770 | 5-HT Receptor |
(S)-Mirtazapine ((S)-Org3770) is the S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a selective 5-HT2 receptor antagonist with pro-nociceptive effects and is often used in combination with the R(-)-enantiomer of Mirt... | |||
T21385 | Cinitapride | Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove | 5-HT Receptor |
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag... | |||
T28167 | NGB 2904 | NGB2904 HCl,NGB-2904,NGB2904 | Others , Dopamine Receptor , 5-HT Receptor |
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... | |||
T30098 | Aplindore Fumarate | Aplindore,DAB-452 Fumarate,DAB-452 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H... | |||
T22987 | MK 212 hydrochloride | 5-HT Receptor | |
MK 212 hydrochloride is a 5-HT2C receptor agonist | |||
T0225 | Pizotifen Malate | Pizotyline (malate),BC-105 (malate),BC-105 | 5-HT Receptor |
Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane. | |||
T1735 | Lurasidone hydrochloride | Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 | Dopamine Receptor , 5-HT Receptor , Norepinephrine |
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag... | |||
T0074L | Chlorprothixene hydrochloride | NSC 78193,Minithixen,Truxal hydrochloride,NSC 56379,NSC 169899,Minithixen hydrochloride | Dopamine Receptor , 5-HT Receptor , Antibacterial , AChR , Histamine Receptor |
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical an... | |||
T4978 | Sarpogrelate hydrochloride | MCI-9042 | 5-HT Receptor |
Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ... | |||
T0162 | Quetiapine | ICI204636,Quetiapin | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor |
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago... | |||
T1539 | Iloperidone | HP 873 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. | |||
T2546 | Pimozide | R6238 | Potassium Channel , Dopamine Receptor , Adrenergic Receptor , STAT |
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby... | |||
T1081 | Naftidrofuryl oxalate | Nafronyl oxalate,Nafronyl oxalate salt | 5-HT Receptor |
Naftidrofuryl oxalate (Nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. It may also be an ant... | |||
T1442 | Pizotifen | Pizotyline,BC-105 | 5-HT Receptor |
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydroch... | |||
T11799 | L-745870 hydrochloride | Dopamine Receptor | |
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 recept... | |||
T6814 | Cyproheptadine hydrochloride | Periactin hydrochloride,Anarexol,Cyproheptadine HCl,Nuran | 5-HT Receptor |
Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist. | |||
T11217 | Eplivanserin | SR-46349 | 5-HT Receptor |
T0174 | Cyproheptadine hydrochloride sesquihydrate | Peritol,Periactin hydrochloride,Cyproheptadine hydrochloride | 5-HT Receptor , Histone Methyltransferase , Histamine Receptor |
Cyproheptadine hydrochloride sesquihydrate (Peritol), an antihistamine, is an antagonist of serotonin and histamine2. | |||
T1412 | Loxapine succinate | Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt | Dopamine Receptor , 5-HT Receptor |
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia. | |||
T23112 | Org37684 | Org 37684 | Others |
5-HT2 receptors agonist | |||
T23246 | Ro 60-0175 fumarate | Others | |
5-HT2 receptor agonist | |||
T23219 | R-96544 hydrochloride | Others | |
5-HT2 receptor antagonist |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T21855 | AMI-193 | Espiramida,Spiramide | Dopamine Receptor , 5-HT Receptor |
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic ... | |||
T6S0659 | Rhynchophylline | Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin | Calcium Channel , NF-κB |
1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in c... | |||
TN1790 | Isopteropodine | Uncarine E | 5-HT Receptor , Antibacterial , AChR |
Isopteropodine (Uncarine E) is an isoyohimbine-type octindole alkaloid isolated from Hamelia patens micropropagated and has antimicrobial activity and stimulates the immune system. Isopteropodine has antimicrobial activi... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-05308 | CD45 Protein, Human, Recombinant (aa 1-529, His) | Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPJ-00854 | ETS1 Protein, Human, Recombinant (His) | Human | E. coli |
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ... | |||
TMPY-05498 | SR-BI/SCARB1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5. | |||
TMPY-05387 | SLAMF7 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-05547 | SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-04318 | GRIK2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar... | |||
TMPK-01363 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01357 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... |