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Search Results for " CCL2 "

ターゲット

Others Histone Methyltransferase Parasite

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T8381	Amodiaquine		Others , Histone Methyltransferase , Parasite
	Amodiaquine is a synthetic aminoquinoline, used to treat malaria.		Others , Histone Methyltransferase , Parasite
T8494	NS-3-008 hydrochloride	NS-3-008 HCl	Others
	NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).		Others
T0381	Amodiaquine dihydrochloride dihydrate	Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate	Histone Methyltransferase , Parasite , Histamine Receptor
	Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.		Histone Methyltransferase , Parasite , Histamine Receptor
T2386	Pirfenidone	S-7701,AMR-69,S-7701,AMR69	CCR , TGF-beta/Smad
	Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...		CCR , TGF-beta/Smad
T12485	Pirfenidone-d5	AMR69 D5,Pirfenidone D5	Others
	Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.		Others
T19854	Evoxine
	Evoxine is a selective inhibitor of CO2-induced immune suppression. It inhibits hypercapnic suppression of interleukin-6 and the chemokine CCL2 expression in human THP-1 macrophages.
T64256	Emapticap pegol
	Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human ...
T76740	Carlumab
	Carlumab (CNTO 888), a humanized antibody with high affinity for CCL2 (chemokine ligand 2), is employed in cancer research, notably in the study of prostate cancer [1].
T62321	ST247
	ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/...
T72970	Rosolic Acid
	Rosolic Acid serves as an Nrf2 activator and influences its downstream targets, enhancing angiogenic factor levels while reducing inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). This compound not ...
T71306	Gemfibrozil-d6
	Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil redu...
T83698	Cathelicidin-2 (128-153) (chicken) TFA	Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
	Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide derived from amino acids 128-153 of chicken CATH-2, demonstrating activity against pathogens such as E. coli, S. aureus, S. enteritidis, and B. globi...
T35463	(±)14(15)-EET	(±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
	(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T37289	Resolvin D2 n-3 DPA	Resolvin D2 n-3 DPA
	Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).1It is formed from docosapentaenoic acid , an intermediate in the conversion of eicosapentaenoic acid to docosahexaenoic acid , in human le...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...

Compounds

Amodiaquine

T8381

Synonym:

Target: Others, Histone Methyltransferase, Parasite

NS-3-008 hydrochloride

T8494

Synonym: NS-3-008 HCl

Target: Others

Amodiaquine dihydrochloride dihydrate

T0381

Synonym: Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate

Target: Histone Methyltransferase, Parasite, Histamine Receptor

Pirfenidone

T2386

Synonym: S-7701,AMR-69,S-7701,AMR69

Target: CCR, TGF-beta/Smad

Pirfenidone-d5

T12485

Synonym: AMR69 D5,Pirfenidone D5

Cathelicidin-2 (128-153) (chicken) TFA

T83698

Synonym: Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)

Target:

(±)14(15)-EET

T35463

Synonym: (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET

Target:

β-Defensin-4 (human) (trifluoroacetate salt)

T35453

Synonym:

Target:

β-Defensin-3 (human) (trifluoroacetate salt)

Synonym: Resolvin D2 n-3 DPA

Target:

β-Defensin-2 (human) (trifluoroacetate salt)

T35451

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T6413	Bindarit	AF2838	CCR
	Bindarit (AF2838) displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.		CCR
TN3614	Cearoin		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of...		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase

天然物製品

Target: ERK, BCL, PARP, IκB/IKK, TNF, NF-κB, ROS, Caspase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00118	MCP-1/CCL2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.
TMPJ-00028	CCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ...
TMPJ-00852	CCL2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the...
TMPK-00916	MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the accession number is P61274.
TMPJ-00009	CCL2 Protein, Human, Recombinant	Human	E. coli
	The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for mono...
TMPK-00011	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPK-00010	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPY-00606	MCP-1/CCL2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPY-05653	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPY-02244	CCL21 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.
TMPY-02828	CCL21 Protein, Rhesus, Recombinant	Rhesus	Baculovirus Insect Cells
	CCL21 Protein, Rhesus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12 kDa and the accession number is Q8HYP5.
TMPY-03935	CCL20 Protein, Human, Recombinant (His)	Human	E. coli
	CCL20 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P78556-1.
TMPY-05089	CCL21a Protein, Mouse, Recombinant	Mouse	Baculovirus Insect Cells
	CCL21a Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.1 kDa and the accession number is P84444.
TMPJ-01341	CCL24 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Cc...
TMPK-01265	CCL24 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPY-03886	MPIF-1/CCL23 Protein, Human, Recombinant	Human	E. coli
	MPIF-1/CCL23 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.4 kDa and the accession number is P55773-1.
TMPY-05472	CCL21a Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	CCL21a Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.5 kDa and the accession number is P84444.
TMPY-02770	CCL20 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	CCL20 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 9.3 kDa and the accession number is O89093-1.
TMPY-03728	CCL28 Protein, Human, Recombinant (His)	Human	E. coli
	CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal su...
TMPJ-01409	CCL27 Protein, Human, Recombinant	Human	E. coli
	Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotact...
TMPY-00168	MPIF-1/CCL23 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3.
TMPK-00704	CCL24 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPK-01195	CCL24 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPY-05353	CCL26 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),...
TMPJ-00019	CCL28 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and i...
TMPK-01196	CCL24 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPY-03779	CCL27 Protein, Human, Recombinant (His)	Human	E. coli
	CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc...
TMPY-04889	CCL20 Protein, Mouse, Recombinant	Mouse	E. coli
	CCL20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.1 kDa and the accession number is O89093-1.
TMPK-00879	CCR2b Protein-VLP, Human, Recombinant	Human	HEK293 Cells
	The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammator...