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Search Results for " VHL "

177

阻害剤

5

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T83649 VHL 15a
T13958 VHL Ligand 8 Others
VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. It efficiently facilitates the degradation of AR protein in AR-positive p...
T7752 (S,R,S)-AHPC-Me VHL ligand 2,E3 ligase Ligand 1A Ligand for E3 Ligase
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a...
T35479 CRBN-6-5-5-VHL
Potent and selective cereblon degrader (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable. ...
T4207 (S,R,S)-AHPC hydrochloride VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride Others , Ligand for E3 Ligase
(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
T8412 (S,R,S)-AHPC VH032-NH2,MDK7526,VHL ligand 1 Others , Ligand for E3 Ligase
(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor.
T17927 (S,R,S)-AHPC TFA VH032-NH2 TFA,VHL ligand 1 TFA Others , Ligand for E3 Ligase
(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to crea...
T13671 (S,R,S)-AHPC-Me hydrochloride VHL ligand 2 hydrochloride,E3 ligase Ligand 1 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cell...
T17922 (S,R,S)-AHPC-PEG3-NH2 hydrochloride VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl Others , E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker.
T18873 VHL Ligand-Linker Conjugates 17 Others
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, ...
T17877 VH032-cyclopropane-F VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101 Others , Ligand for E3 Ligase
VH032-cyclopropane-F (Phenolic VH101) is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
T17908 VHL Ligand-Linker Conjugates 15 E3 Ligase Ligand-Linker Conjugates 56 Others
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1].
T82928 Azido-PEG2-VHL PROTACs
Azido-PEG2-VHL is a multikinase degrader utilized in PROTACs (PROteolysis TArgeting Chimeras) synthesis [1].
T17921 (S,R,S)-AHPC-PEG4-N3 VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 Others , PROTAC Linker
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both c...
T17924 (S,R,S)-AHPC-PEG2-NH2 hydrochloride VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6 Others , E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit...
T17909 (S,R,S)-AHPC-PEG3-N3 VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12 Others , E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase
(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC tec...
T79720 VHL-IN-1 HIF/HIF Prolyl-Hydroxylase
VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1α and enhances its transcriptional activity. It shows promise for appli...
T18640 (S,R,S)-AHPC-C4-NH2 hydrochloride VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
T17920 (S,R,S)-AHPC-PEG1-N3 VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG1-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC tec...
T15190L (S,R,S)-AHPC-PEG4-NH2 VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
T18600 VH032 thiol VHL ligand 6 Others
VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
T17925 (S,R,S)-AHPC-PEG2-NH2 VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base Others , E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis ...
T2363 STF-31 transporter , Autophagy
STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.
T13876 (S,R,S)-AHPC-propargyl VHL ligand 7,VH032-propargyl Others
(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs.
T18602 VH032-thiol-C6-NH2 VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29 Others
VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonl...
T6683 STF-62247 STF 62247 Estrogen/progestogen Receptor , Autophagy
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
T17911 (S,R,S)-AHPC-C6-PEG3-C4-Cl VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8 Others
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in ce...
T17912 (S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11 Others
(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-Ha...
T18872 (S,R,S)-AHPC-PEG5-COOH VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16 Others
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1].
T17905 (S,R,S)-AHPC-PEG1-OTs VH032-PEG1-OTs,VHL Ligand-Linker Conjugates 2,E3 ligase Ligand-Linker Conjugates 51 Others
(S,R,S)-AHPC-PEG1-OTs is a chemically synthesized conjugate, functioning as an ligase ligand-linker for E3 ligase. It incorporates the VHL ligand derived from (S,R,S)-AHPC and a 1-unit PEG linker. This synthesized compou...
T17913 (S,R,S)-AHPC-PEG2-N3 VHL Ligand-Linker Conjugates 6,VH032-PEG2-N3,E3 ligase Ligand-Linker Conjugates 13 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.
T17926 (S,R,S)-AHPC-PEG6-C4-Cl VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl Others
(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas...
T17910 (S,R,S)-AHPC-PEG2-C4-Cl E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl Others
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas...
T12186 Navitoclax-piperazine ABT-263-piperazine BCL , Ligands for Target Protein for PROTAC
Navitoclax-piperazine (ABT-263-piperazine) is an inhibitor of B-cell lymphoma extra large (BCL-XL).
T13671L (S,R,S)-AHPC-Me dihydrochloride VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base) Others
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demon...
T17923 (S,R,S)-AHPC-PEG3-NH2 E3 ligase Ligand-Linker Conjugates 5 Free Base,VH032-PEG3-NH2,VHL Ligand-Linker Conjugates 1 Others
(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology.
T15190 (S,R,S)-AHPC-PEG4-NH2 hydrochloride E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride Others
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically ...
T17881 (S,R,S)-AHPC-C10-NH2 VH032-C10-NH2 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
T18661 (S,R,S)-AHPC-C10-NH2 dihydrochloride VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine Others , Ligand for E3 Ligase
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
T13722 Homo-PROTAC pVHL30 degrader 1 Others , Ligand for E3 Ligase
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
T36275 XStAx-VHLL
Selective peptide-based β-catenin Degrader. Comprises a β-catenin-targeted stapled peptide, xStAx, linked to a VHL-binding peptide. Reduces β-catenin levels in HEK293T cells and colorectal cancer cell lines. Selectively ...
TQ0121 VH-298 Others , HIF , Ligand for E3 Ligase
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by P...
T40028 (S,R,S)-AHPC Ligand for E3 Ligase
(S,R,S)-AHPC is a VHL ligand that used in the recruitment of the VHL protein.
T29106 VH032 VH-032,VH 032 Ligand for E3 Ligase
VH032 commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component.VH032 is a VHL/HIF-1α interaction inhibitor with a KdPROTACs, which can recruit von Hippel-Lindau (VHL) proteins as a l...
T13877 (S,S,S)-AHPC hydrochloride (S,S,S)-VH032-NH2 hydrochloride Ligand for E3 Ligase
(S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the recruitment of the VHL pro...
T18669L (S,R,S)-AHPC-Me-C10-NH2 hydrochloride Ligand for E3 Ligase
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating a VHL ligand and a linker.
T5334 VL285 Others , Ligand for E3 Ligase
VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
T18787 TD-165 Others , Ligand for E3 Ligase
TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, and a von Hippel-Landau (VHL) binding group[1].
T18675 (S,R,S)-AHPC-PEG2-NH2 dihydrochloride VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1].
T10359 AR antagonist 1 Androgen Receptor , Ligand for E3 Ligase , Ligands for Target Protein for PROTAC
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.

Compounds

VHL 15a
T83649
Synonym:
Target:
VHL Ligand 8
T13958
Synonym:
Target: Others
(S,R,S)-AHPC-Me
T7752
Synonym: VHL ligand 2,E3 ligase Ligand 1A
Target: Ligand for E3 Ligase
CRBN-6-5-5-VHL
T35479
Synonym:
Target:
(S,R,S)-AHPC hydrochloride
T4207
Synonym: VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC
T8412
Synonym: VH032-NH2,MDK7526,VHL ligand 1
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC TFA
T17927
Synonym: VH032-NH2 TFA,VHL ligand 1 TFA
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-Me hydrochloride
T13671
Synonym: VHL ligand 2 hydrochloride,E3 ligase Ligand 1
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
T17922
Synonym: VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl
Target: Others, E3 Ligase Ligand-Linker Conjugate
VHL Ligand-Linker Conjugates 17
T18873
Synonym:
Target: Others
VH032-cyclopropane-F
T17877
Synonym: VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101
Target: Others, Ligand for E3 Ligase
VHL Ligand-Linker Conjugates 15
T17908
Synonym: E3 Ligase Ligand-Linker Conjugates 56
Target: Others
Azido-PEG2-VHL
T82928
Synonym:
Target: PROTACs
(S,R,S)-AHPC-PEG4-N3
T17921
Synonym: VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4
Target: Others, PROTAC Linker
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
T17924
Synonym: VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6
Target: Others, E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-PEG3-N3
T17909
Synonym: VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12
Target: Others, E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase
VHL-IN-1
T79720
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
(S,R,S)-AHPC-C4-NH2 hydrochloride
T18640
Synonym: VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-PEG1-N3
T17920
Synonym: VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-PEG4-NH2
T15190L
Synonym: VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2
Target: Others, Ligand for E3 Ligase
VH032 thiol
T18600
Synonym: VHL ligand 6
Target: Others
(S,R,S)-AHPC-PEG2-NH2
T17925
Synonym: VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base
Target: Others, E3 Ligase Ligand-Linker Conjugate
STF-31
T2363
Synonym:
Target: transporter, Autophagy
(S,R,S)-AHPC-propargyl
T13876
Synonym: VHL ligand 7,VH032-propargyl
Target: Others
VH032-thiol-C6-NH2
T18602
Synonym: VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29
Target: Others
STF-62247
T6683
Synonym: STF 62247
Target: Estrogen/progestogen Receptor, Autophagy
(S,R,S)-AHPC-C6-PEG3-C4-Cl
T17911
Synonym: VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8
Target: Others
(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl
T17912
Synonym: VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11
Target: Others
(S,R,S)-AHPC-PEG5-COOH
T18872
Synonym: VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16
Target: Others
(S,R,S)-AHPC-PEG1-OTs
T17905
Synonym: VH032-PEG1-OTs,VHL Ligand-Linker Conjugates 2,E3 ligase Ligand-Linker Conjugates 51
Target: Others
(S,R,S)-AHPC-PEG2-N3
T17913
Synonym: VHL Ligand-Linker Conjugates 6,VH032-PEG2-N3,E3 ligase Ligand-Linker Conjugates 13
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-PEG6-C4-Cl
T17926
Synonym: VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl
Target: Others
(S,R,S)-AHPC-PEG2-C4-Cl
T17910
Synonym: E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl
Target: Others
Navitoclax-piperazine
T12186
Synonym: ABT-263-piperazine
Target: BCL, Ligands for Target Protein for PROTAC
(S,R,S)-AHPC-Me dihydrochloride
T13671L
Synonym: VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base)
Target: Others
(S,R,S)-AHPC-PEG3-NH2
T17923
Synonym: E3 ligase Ligand-Linker Conjugates 5 Free Base,VH032-PEG3-NH2,VHL Ligand-Linker Conjugates 1
Target: Others
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
T15190
Synonym: E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride
Target: Others
(S,R,S)-AHPC-C10-NH2
T17881
Synonym: VH032-C10-NH2
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-C10-NH2 dihydrochloride
T18661
Synonym: VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine
Target: Others, Ligand for E3 Ligase
Homo-PROTAC pVHL30 degrader 1
T13722
Synonym:
Target: Others, Ligand for E3 Ligase
xStAx-VHLL
T36275
Synonym:
Target:
VH-298
TQ0121
Synonym:
Target: Others, HIF, Ligand for E3 Ligase
(S,R,S)-AHPC
T40028
Synonym:
Target: Ligand for E3 Ligase
VH032
T29106
Synonym: VH-032,VH 032
Target: Ligand for E3 Ligase
(S,S,S)-AHPC hydrochloride
T13877
Synonym: (S,S,S)-VH032-NH2 hydrochloride
Target: Ligand for E3 Ligase
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride
T18669L
Synonym:
Target: Ligand for E3 Ligase
VL285
T5334
Synonym:
Target: Others, Ligand for E3 Ligase
TD-165
T18787
Synonym:
Target: Others, Ligand for E3 Ligase
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride
T18675
Synonym: VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12
Target: Others, Ligand for E3 Ligase
AR antagonist 1
T10359
Synonym:
Target: Androgen Receptor, Ligand for E3 Ligase, Ligands for Target Protein for PROTAC
1 2 3 4

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-06026 VHL Protein, Human, Recombinant (His & Avi) Human E. coli
VHL Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with His and Avi tag. The predicted molecular weight is 27.5 kDa and the accession number is A0A024R2F2.
TMPJ-01138 UBE2S Protein, Human, Recombinant (GST) Human E. coli
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activat...
TMPY-03398 FHIT Protein, Human, Recombinant (His) Human E. coli
Fragile histidine triad, also known as FHIT, may play a key role in differentiating humans from apes. Fragile histidine triad gene belongs to the histidine triad gene family. It has been shown that fragile histidine tria...
TMPH-01288 Elongin-B Protein, Human, Recombinant (GST) Human E. coli
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its...
TMPH-01512 HIF1AN Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coa...