|
T11465 |
Lenacapavir
|
GS-6207 |
Others
,
HIV Protease
|
|
|
|
T2578 |
Didanosine
|
ddI,2',3'-Dideoxyinosine |
HIV Protease
,
Reverse Transcriptase
|
|
Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM). |
|
T6098 |
Cabotegravir
|
GSK744,GSK-1265744,S/GSK1265744 |
HIV Protease
|
|
Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM). |
|
T19963 |
Alizarin Complexone
|
Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid |
Reverse Transcriptase
|
|
Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies... |
|
T4326 |
AG 555
|
Tyrphostin B46,Tyrphostin AG 555 |
EGFR
,
Reverse Transcriptase
|
|
AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor. |
|
T1404 |
Stavudine
|
d4T,Sanilvudine,BMY-27857,NSC 163661 |
Apoptosis
,
Nucleoside Antimetabolite/Analog
,
HIV Protease
,
NOD-like Receptor (NLR)
,
Reverse Transcriptase
,
Autophagy
|
|
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV. |
|
T27154 |
Dexelvucitabine
|
D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC |
Reverse Transcriptase
|
|
Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. |
|
T8238 |
Fosamprenavir Calcium Salt
|
Diallyl Trisulfide,GW433908G |
HIV Protease
|
|
Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection. |
|
T30047 |
Ancriviroc
|
Schering C,SCH-351125,[3H]ancriviroc,CHEMBL336672,AC1NUILE |
HIV Protease
|
|
Ancriviroc(CHEMBL336672), an imidoxime with strong antiretroviral activity, is a potent CCR5 inhibitor that can be used to study HIV. |
|
T7903 |
Saquinavir
|
Ro 31-8959 |
SARS-CoV
,
HIV Protease
|
|
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. |
|
T14313 |
Apricitabine
|
AVX754,SPD754 |
HIV Protease
,
DNA/RNA Synthesis
|
|
Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a... |
|
T5949 |
Dideoxyadenosine
|
|
|
|
2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1]. |
|
T2409 |
Tenofovir alafenamide
|
GS-7340 |
HIV Protease
,
Reverse Transcriptase
|
|
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir. |
|
T7779 |
Nelfinavir
|
AG1341 |
HIV Protease
|
|
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent. |
|
T1595 |
Nevirapine
|
NSC 641530,BI-RG 587,NVP |
HIV Protease
,
Reverse Transcriptase
|
|
Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preve... |
|
T11538 |
Hck-IN-1
|
|
HIV Protease
,
Src
,
Hck
|
|
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w... |
|
T80644 |
DNA polymerase-IN-1
|
|
Antiviral
,
DNA/RNA Synthesis
|
|
DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I... |
|
T28946 |
Tenofovir exalidex
|
Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157 |
Antiviral
|
|
Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleosi... |
|
T68666 |
Benfluron Hydrochloride
|
|
|
|
Benfluron Hydrochloride is an inhibitor of HIV-1 Rev function which also acts as a cytostatic agent with substantial antiretroviral activity. |
|
T24839 |
Stampidine
|
HI-113,HI 113,HI113 |
|
|
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical... |
|
T5863L |
Indinavir
|
MK-639,L 735 524,Crixivan |
|
|
Indinavir (IDV) is an inhibitor of protease that is used as part of highly active antiretroviral therapy for the treatment of HIV/AIDS. |
|
T68376 |
Indinavir lactone
|
|
|
|
Indinavir lactone is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS. |
|
T8156 |
Saquinavir mesylate
|
Ro 31-8959/003 |
HIV Protease
,
Autophagy
|
|
Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy |
|
T25535 |
Indinavir, threo-
|
Threo-indinavir,Indinavir sulfate specified impurity C |
|
|
Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS. |
|
TP1332 |
Enfuvirtide
|
|
|
|
Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. |
|
T71518 |
Zidovudine diphosphate
|
|
|
|
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas... |
|
T79837 |
Bavtavirine
|
|
|
|
Bavtavirine, a potent non-nucleoside reverse transcriptase inhibitor (NNRTI), forms an integral component of the highly active antiretroviral therapy (HAART) regimen for HIV disease research [1]. |
|
T7212L |
Delavirdine
|
Rescriptor,DLV,U 90152,BHAP-U 90152 |
|
|
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine is part of Highly Active Antiretroviral Therapy (HAART), which can be used to treat human immunodeficiency virus (HIV) type 1. |
|
T82536 |
DNA polymerase-IN-4
|
|
|
|
DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1]. |
|
T71983 |
Zidovudine glucuronide
|
|
|
|
Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas... |
|
T26726 |
AzddMeC
|
CS-92,Azidodideoxymethylcytidine,Az-Dcme |
HIV Protease
|
|
AzddMeC (Az-Dcme) is an orally active, potent and selective inhibitor of HIV-1 reverse transcriptase and HIV-1 replication with antiretroviral activity.AzddMeC may be used in the study of HIV-1 infections. |
|
T70596 |
Emtricitabine triphosphate
|
(-)-Emtricitabine triphosphate |
|
|
Emtricitabine triphosphate ((-)-Emtricitabine triphosphate), the phosphorylated anabolite of Emtricitabine, serves as a nucleoside reverse transcriptase inhibitor and antiretroviral agent against HIV and HBV [1] [2]. |
|
T62328 |
Cabotegravir sodium
|
|
|
|
Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less li... |
|
T4555 |
Fosamprenavir
|
GW 433908,Amprenavir phosphate |
|
|
Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility over the parent molecule[1]. It has anti- HIV infection effect [1]... |
|
T80621 |
Semzuvolimab
|
UB421 |
|
|
Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4). It has demonstrated capabilities to neutralize HIV infection and may inhibit HIV in patients on stable highly active antiretro... |
|
T76292 |
Tifuvirtide
|
|
|
|
Tifuvirtide (T-1249) is a synthetically designed peptide and a fusion inhibitor targeting human immunodeficiency virus type-1 (HIV-1), exhibiting antiretroviral activity. This hybrid retroviral envelope polypeptide is ut... |
|
T61311 |
HIV-1 inhibitor-30
|
|
|
|
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM.... |
|
T73837 |
AZT triphosphate tetraammonium
|
|
|
|
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replicati... |
|
T36490 |
AZT triphosphate TEA
|
|
|
|
AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT tr... |
|
T83732 |
Tat-CBD3A6K TFA
|
|
|
|
Tat-CBD3A6K, a peptide derivative of the N-type voltage-gated calcium channel Cav2.2 and collapsin response mediator protein 2 (CRMP2) interaction inhibitor Tat-CBD3, has demonstrated efficacy in a rat model of antiretro... |
