|
T30873 |
Chelator 1a
|
Chelator1a,Chelator-1a |
Antifungal
|
|
Chelator 1a has antifungal activity, inhibiting Aspergillus and Candida, and can be used to study fungal infections and cancer. |
|
T8500 |
VLX600
|
|
OXPHOS
,
Mitochondrial Metabolism
,
Autophagy
|
|
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells. |
|
T7098 |
BAPTA
|
|
Reactive Oxygen Species
|
|
BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator. |
|
T4585 |
EGTA
|
Ethylenebis(oxyethylenenitrilo)tetraacet |
Others
|
|
Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively. |
|
T39477 |
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
|
Ca-DTPA trisodium salt hydrate |
Others
|
|
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Ca-DTPA tris... |
|
T1457 |
Deferasirox
|
ICL 670,CGP-72670 |
Others
,
Ferroptosis
,
Antibacterial
|
|
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload. |
|
T14667 |
BLT-1
|
|
Others
,
HCV Protease
|
|
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor. |
|
T19692 |
Deferitrin
|
GT 56252,GT 56 252,GT-56252,GT-56-252 |
Others
|
|
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload. |
|
T31362 |
Deferitazole
|
SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602 |
Others
|
|
Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator. |
|
T2229 |
Tetraethylenepentamine Pentahydrochloride
|
|
Others
|
|
Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator. |
|
T9956 |
VK-28
|
|
Mitochondrial Metabolism
,
Lipid
|
|
VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation. |
|
T22373 |
ADA
|
ADA buffer,N-(2-Acetamido)-2-Iminodiacetic acid |
Others
|
|
ADA (N-(2-Acetamido)-2-Iminodiacetic acid) is a biological buffer which can serve as a chelator[1][2]. |
|
T73718 |
MDCG sodium
|
NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium |
Endogenous Metabolite
|
|
MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) is a metal chelator that promotes biliary excretion of Cd. |
|
T1565 |
Deferiprone
|
Deferidone,CP20 |
Others
,
HCV Protease
,
Ferroptosis
,
UGT
|
|
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity. |
|
T32046 |
HBED
|
CHELII,CHEL II,CHEL-II |
Others
|
|
HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning. |
|
T34956 |
Triplin
|
|
Others
|
|
Triplin is a chelator of copper ion. Triplin affects the transport of copper ions from ATX1 to RAN1. |
|
T5314 |
Pyridoxal isonicotinoyl hydrazone
|
PIH |
Others
|
|
pyridoxal isonicotinoyl hydrazone (PIH) is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo. |
|
T6821 |
Dp44mT
|
|
Apoptosis
,
Others
,
Ferroptosis
|
|
Dp44mT, a effective iron chelator, has selective antitumor activity. |
|
T5344 |
SP-420
|
SP 420 |
Others
|
|
SP-420 is a novel orally active iron chelator. |
|
T3952 |
TPEN
|
TPEDA |
Apoptosis
,
Reactive Oxygen Species
,
Autophagy
|
|
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. |
|
T15213 |
Emeramide
|
BDTH2 |
Reactive Oxygen Species
|
|
Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator. |
|
T2552 |
Succimer
|
DMSA,Dimercaptosuccinic acid,meso-2,3-dimercaptosuccinic acid |
Others
|
|
Succimer (Dimercaptosuccinic acid) is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity. |
|
T22305 |
Dexrazoxane
|
ICRF-187 |
Others
|
|
Dexrazoxane (ICRF-187) is an anticancer drug used to block mitosis and arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity. |
|
T13639 |
Deferasirox (Fe3+ chelate)
|
|
Apoptosis
|
|
Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload. |
|
T38681 |
P-SCN-Bn-DOTA
|
|
Others
|
|
p-SCN-Bn-DOTA is a chelator that simultaneously chelates radionuclides and connects monoclonal antibodies. It can be used as a tracer for radio-guided surgery and can be used for radio-immunoassay studies of tumors. |
|
T65636 |
BIS-TRIS propane
|
BTP |
Others
|
|
BIS-TRIS propane (BTP), a novel multidentate ligand of nickel- and cobalt-based spin clusters, is a metal chelator. BIS-TRIS propane is often used as a zwitterionic buffer for PCR and protein crystallization studies. |
|
T5983 |
O-Phenanthroline
|
1,10-Phenanthroline |
MMP
,
Others
|
|
o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m... |
|
T65167 |
EDTA copper(II) disodium salt
|
|
Antibiotic
|
|
EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory and antioxidant activity, slows down damage caused by metal ions, maintains osmotic pressure during protein purification, and can be... |
|
T1637 |
Deferoxamine Mesylate
|
desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM |
Mitophagy
,
Beta Amyloid
,
Others
,
Ferroptosis
,
HIF/HIF Prolyl-Hydroxylase
,
Autophagy
|
|
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i... |
|
T6245 |
BAPTA-AM
|
BAPTA/AM |
Potassium Channel
|
|
BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM). BAPTA-AM has a 105-fold higher affinity for Ca2+ than for Mg2+, and can be used for... |
|
T38034 |
MAO-IN-M30 dihydrochloride
|
M 30 dihydrochloride |
Monoamine Oxidase
|
|
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant... |
|
T66155 |
EDTA, Disodium Salt, Dihydrate
|
Ethylenediaminetetraacetic acid disodium dihydrate |
Protease
|
|
EDTA, Disodium Salt, Dihydrate (Ethylenediaminetetraacetic acid disodium dihydrate) is a metal ion chelator used as a protease inhibitor.EDTA, Disodium Salt, Dihydrate is a molecule that is ineffective against cellulase ... |
|
T124358 |
Deferoxamine
|
Deferoxamine B,Desferrioxamine B |
Apoptosis
,
Antioxidant
,
HIF
,
Autophagy
|
|
Deferoxamine（Desferrioxamine B） is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may imp... |
|
TD0097 |
BAPTA, tetrapotassium salt
|
BAPTA-AM |
|
|
BAPTA, tetrapotassium salt is a Ca2+ chelator. |
|
T68766 |
Dp2mT
|
|
|
|
Dp2mT is an iron chelator which inhibits HIV-1 transcription. |
|
T13607 |
CGP 65015
|
|
Others
|
|
|
|
T31552 |
DMNP-EDTA
|
DMNPEDTA,DM-Nitrophen,DM Nitrophen,DMNP EDTA |
|
|
DMNP-EDTA is a caged Ca2+ chelator which photouncages Cu2+ ions for light-controlled gene expression in yeast. |
|
T40337 |
Salpyran
|
|
|
|
Salpyran is a Cu(II) selective chelator with therapeutic potential. |
|
T28464 |
P-SCN-Bn-TCMC HCl
|
p-SCN-Bn-TCMC |
|
|
p-SCN-Bn-TCMC is a bifunctional chelator, it contains a powerful chelator TCMC and reactive tioisocyante linker. TCMC is a powerful chelator with capability to strongly bind radio-isotopic heavy metal ion, which are wide... |
|
T19050 |
Quin-2AM
|
Quin-2 acetoxymethyl ester |
Others
|
|
Quin-2AM is a fluorescent Ca2+ chelator with a high affinity for calcium. |
|
T30852 |
CGP-75254A
|
CGP 75254A,UNII-94KC20I6YX,CGP75254A |
|
|
CGP-75254A is a novel oral iron chelator. |
|
T32807 |
LK-614
|
LK614 |
|
|
LK-614 is a newly developed iron chelator. |
|
T31387 |
Desferrithiocin
|
DFT |
|
|
Desferrithiocin is a more active iron chelator than desferrioxamine. |
|
T30852L |
CGP-75254A Free Acid
|
CGP-75254A |
|
|
CGP-75254A Free Acid is a novel oral iron chelator. |
|
T31363 |
Deferitazole magnesium
|
FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base |
|
|
Deferitazole magnesium is a potential chelator for iron overload treatment. |
|
T81223 |
Salpyran hydrochloride
|
|
|
|
Salpyran is a selective chelator for Cu(II) ions, exhibiting potential therapeutic applications [1]. |
|
T13673 |
EGTA-AM
|
EGTA Acetoxymethyl ester |
Others
|
|
EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia. |
|
T39366 |
Corixetan
|
|
|
|
Corixetan is a potent thorium chelator that effectively forms stable complexes with Th-227 in vivo. |
|
T34665 |
SN-1
|
SN1 |
|
|
SN-1 is a zinc chelator which increases steady-state expression level of A3G in the presence of Vif. |
|
T68438 |
APO-6619
|
|
|
|
APO-6619 is an iron chelator which was shown to inhibit growth of the following bacterial strains: Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli. AP... |
