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ターゲット

Apoptosis BCL

123

阻害剤

天然化合物

184

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T5210	BAI1		Apoptosis , BCL
	BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).		Apoptosis , BCL
T2199	Myclobutanil	Systhane	Antifungal
	Myclobutanil (Systhane) is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes.		Antifungal
T7459	Abametapir	HA-44,BRN 0123183	MMP , Others , Parasite
	Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.		MMP , Others , Parasite
T24212	XX-650-23	XX65023,XX 650 23	Apoptosis , Epigenetic Reader Domain
	XX-650-23 is a small molecule CREB inhibitor that blocks the critical interaction between CREB and its required coactivator, CBP (CREB-binding protein), inducing apoptosis and cell cycle arrest in AML cells, and can be u...		Apoptosis , Epigenetic Reader Domain
T3940	CID5721353	BCL6 inhibitor	Apoptosis , BCL
	CID5721353 (BCL6 inhibitor) is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove.		Apoptosis , BCL
T4647	M2I-1	M2I 1	Others
	M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri...		Others
T6386	Ampicillin sodium	Domicillin,D-(-)-α-Aminobenzylpenicillin sodium salt,Penialmen,Citteral	Antibacterial , Antibiotic
	Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium (Domicillin) inhibits bacterial cell wall synthesis by binding to penicillin bindin...		Antibacterial , Antibiotic
T73616	Glutamate dehydrogenase (NAD(P))
	Glutamate dehydrogenase NAD(P) (GLDH), a mitochondrial enzyme located in hepatocytes, renal tissue, brain, muscle, and intestinal cells, catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-K...
T6904	Necrosulfonamide	(E)-Necrosulfonamide	MLK
	(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec...		MLK
T1433	Ritodrine hydrochloride	DU21220,Ritodrine HCl,NSC 291565	Adrenergic Receptor
	Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NS...		Adrenergic Receptor
T9574	PF-07304814	Lufotrelvir
	Lufotrelvir (PF-07304814) is a phosphate prodrug of PF-00835231 which acts as a potent 3CL pro protease ( M pro ) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CL pro activity w...
T2170	SKF-96365 hydrochloride	SKF96365	Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
	SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
T4013	SGC2085 HCl		Histone Methyltransferase
	SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulat...		Histone Methyltransferase
T14134	Afabicin	AFN-1720,Debio 1450	Antibacterial
	Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.		Antibacterial
T28807	SLUPP-225	SLUPP 225
	SLUPP-225 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T10046	16,16-Dimethyl prostaglandin E2	16,16-dimethyl PGE2	Prostaglandin Receptor
	16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.		Prostaglandin Receptor
T34458	Ryanodol
	Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission.
T28808	SLUPP-417	SLUPP417
	SLUPP-417 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T74122	Deoxythymidine-5'-triphosphate sodium hydrate
	Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate, a critical nucleoside triphosphate among four, serves as a trisodium salt in DNA synthesis [1].
T38614	TLR7 agonist 3
	TLR7 agonist 3 (Compound 2), a potent activator of toll-like receptor 7 (TLR7), plays a critical role in initiating immune responses, positioning it as a promising target for immunomodulator development.
T40456	8-Bromoadenosine 5'-triphosphate tetrasodium	8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium
	8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vi...
T27068	CPI098	CPI-098,CPI 098
	CPI098 is a potent and selective inhibitors for the bromodomains of CREBBP/EP300. CREBBP/EP300 bromodomains play a critical role in regulatory T cell biology. T cell recruitment to tumors is a major mechanism of immune e...
T40781	Geranylgeranyl pyrophosphate
	Geranylgeranyl pyrophosphate, a key metabolite in protein geranylgeranylation, serves as the universal precursor for diterpenoids, such as Paclitaxel. Its role in cancer research stems from this critical function.
T82589	Delpacibart
	Delpacibart is a humanized mouse IgG1κ antibody that targets TFRC, a critical membrane protein regulating intracellular iron transport [1].
T73107	RAD51-IN-4
	RAD51-IN-4 is a potent RAD51 inhibitor, targeting a eukaryote gene critical for studies on conditions associated with mitochondrial defects.
T16592	Propargyl-PEG1-SS-PEG1-propargyl		Others
	Propargyl-PEG1-SS-PEG1-propargyl refers to a cleavable di-functional polyethylene glycol (PEG) linker composed of two units. This specific linker is employed in the synthesis of antibody-drug conjugates (ADCs), where it ...		Others
T18630	Tos-PEG3-NH-Boc	PROTAC Linker 9	Others
	Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based linker utilized for the synthesis of PROTACs. It plays a critical role in facilitating the connection between a target protein and an E3 ubiquitin ligase, ultimately leadi...		Others
T18268	Mal-PEG1-Val-Cit-PABC-OH		Others
	Mal-PEG1-Val-Cit-PABC-OH is a 1 unit polyethylene glycol (PEG) ADC linker that possesses cleavable properties. This linker, commonly utilized in the synthesis of antibody-drug conjugates (ADCs), serves as a critical comp...		Others
T68291	APSR-IN-8
	APSR-IN-8 is a first-in-class inhibitor of APS reductase (APSR), which is a critical enzyme in the assimilation of sulfate for the biosynthesis of cysteine and other essential sulfur-containing molecules.
T80055	Beta-glucuronidase (bovine liver)
	Beta-glucuronidase, a critical lysosomal enzyme, is implicated in the breakdown of glucuronate-containing glycosaminoglycans [1].
T25749	L-NIL dihydrochloride	L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride
	L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical r...
T18618	Bis-NH2-C1-PEG3	PROTAC Linker 24	Others
	Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs. This compound serves as a critical component in constructing PROTAC molecules, facilitating th...		Others
T75410	Ganglioside sialidase (AuSialidase S)
	Ganglioside sialidase (AuSialidase S), an endogenous metabolite, plays a critical role in neuronal differentiation, specifically in neurite outgrowth [1].
T60363	Nitrefazole
	Nitrefazole, a 4-nitroimidazole derivative, exhibits potent and prolonged inhibition of aldehyde dehydrogenase (ALDH), an enzyme critical for alcohol metabolism.
T80397	Darobactin		Antibiotic
	Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].		Antibiotic
T36365	KAPA (hydrochloride)	KAPA (hydrochloride),7-keto-8-Aminopelargomic Acid
	Biotin is a growth factor that plays an important role in numerous reactions that are critical to microorganisms, plants, and animals. Biotin has a strong affinity for the protein avidin, a trait that has been utilized f...
T69830	GSK2239633
	GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2...
TD0052	Fluo-3, pentasodium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c...
T78356	Fructosyl amino acid oxidase
	Fructosyl amino acid oxidase is utilized for the quantification of glycosylated proteins, particularly glycosylated hemoglobin A1c, which serves as a critical biomarker for assessing diabetes treatment efficacy [1].
T61554	CSF1R-IN-13
	CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell...
T74318	18:0 EPC chloride
	18:0 EPC chloride, a synthetic cationic phospholipid, significantly enhances eugenol's inactivation effect on Escherichia coli [1] when used at critical synergistic concentrations ranging from 2.34 to 2.93 μM.
T82403	Fibronectin Type III Connecting Segment Fragment 1-25
	Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide implicated in melanoma cell adhesion and critical for the development of the chicken peripheral nervous system [1] [2].
T75971	γ-1-Melanocyte Stimulating Hormone (MSH), amide
	γ-1-Melanocyte Stimulating Hormone (MSH), amide, a peptide consisting of 11 amino acids, plays a critical role in regulating sodium (Na+) balance and blood pressure by activating melanocortin receptor 3 (MC3-R).
T68755	NZ-28
	NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcript...
TD0053	Fluo-3, pentapotassium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c...
TD0054	Fluo-3, pentaammonium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c...
T74435	Alicaforsen sodium
	Alicaforsen sodium is a 20-base antisense oligonucleotide that targets and inhibits the production of ICAM-1, a critical adhesion molecule responsible for mediating leukocyte migration and trafficking toward inflammation...
T71340	Mizagliflozin sebacate
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from...
T78004	Neuromedin U, rat TFA	Rat neuromedin U-23 TFA,Neuromedin U (rat) (TFA)
	Neuromedin U (rat TFA), a 23-amino acid brain-gut peptide, operates via its specific receptor NMUR2 in the central nervous system to modulate critical physiological processes such as energy homeostasis, stress response, ...
T37715	Galactosylcerebrosides (bovine)
	Galactosylcerebrosides (SGal-CB) are expressed by Schwann cells (SCs) in the peripheral nervous system (PNS) during the early stages of myelination, and their persistence in the sheath is critical for long-term maintenan...

Compounds

BAI1

T5210

Synonym:

Target: Apoptosis, BCL

Synonym: HA-44,BRN 0123183

Target: MMP, Others, Parasite

XX-650-23

T24212

Synonym: XX65023,XX 650 23

Target: Apoptosis, Epigenetic Reader Domain

CID5721353

T3940

Synonym: BCL6 inhibitor

Target: Apoptosis, BCL

Synonym: Domicillin,D-(-)-α-Aminobenzylpenicillin sodium salt,Penialmen,Citteral

Target: Antibacterial, Antibiotic

Glutamate dehydrogenase (NAD(P))

Synonym: (E)-Necrosulfonamide

Target: MLK

Ritodrine hydrochloride

T1433

Synonym: DU21220,Ritodrine HCl,NSC 291565

Target: Adrenergic Receptor

SKF-96365 hydrochloride

T2170

Synonym: SKF96365

Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy

SGC2085 HCl

T4013

Synonym:

Target: Histone Methyltransferase

Afabicin

T14134

Synonym: AFN-1720,Debio 1450

Target: Antibacterial

16,16-Dimethyl prostaglandin E2

T10046

Synonym: 16,16-dimethyl PGE2

Target: Prostaglandin Receptor

Deoxythymidine-5'-triphosphate sodium hydrate

8-Bromoadenosine 5'-triphosphate tetrasodium

T40456

Synonym: 8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium

Target:

CPI098

T27068

Synonym: CPI-098,CPI 098

Target:

Geranylgeranyl pyrophosphate

Propargyl-PEG1-SS-PEG1-propargyl

Synonym: PROTAC Linker 9

Target: Others

Mal-PEG1-Val-Cit-PABC-OH

Beta-glucuronidase (bovine liver)

T80055

Synonym:

Target:

L-NIL dihydrochloride

T25749

Synonym: L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride

Target:

Bis-NH2-C1-PEG3

T18618

Synonym: PROTAC Linker 24

Target: Others

Ganglioside sialidase (AuSialidase S)

Synonym: KAPA (hydrochloride),7-keto-8-Aminopelargomic Acid

Fluo-3, pentasodium salt

TD0052

Synonym:

Target:

Fructosyl amino acid oxidase

Fibronectin Type III Connecting Segment Fragment 1-25

T82403

Synonym:

Target:

γ-1-Melanocyte Stimulating Hormone (MSH), amide

Fluo-3, pentapotassium salt

TD0053

Synonym:

Target:

Fluo-3, pentaammonium salt

Mizagliflozin sebacate

T71340

Synonym:

Target:

Neuromedin U, rat TFA

T78004

Synonym: Rat neuromedin U-23 TFA,Neuromedin U (rat) (TFA)

Target:

Galactosylcerebrosides (bovine)

T37715

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T3909	Pulsatilla saponin D	Hederacolchiside A,SB365	Apoptosis , Others
	Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apopt...		Apoptosis , Others
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
T5S0527	Rhodojaponin III		Others
	1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja...		Others
T19316	Ethyl oleate		Others
	Ethyl oleate, a fatty acid ester produced through the condensation of oleic acid and ethanol, serves as the liquid lipid component in nanostructured lipid carriers (NLCs). These NLCs represent a pioneering approach for t...		Others
T36585	Isodeoxycholic Acid	isoDCA	Chloride channel , Antibacterial
	Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less...		Chloride channel , Antibacterial
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
TN2655	17alpha-Neriifolin		Others
	17alpha-Neriifolin and 17alpha-Deacetyltanghinin have little anti-proliferative activity, indicating that the 17beta configuration is critical for the anti-proliferative activity of these compounds.		Others
T82636	Cyclosporin U
	Cyclosporin U (SMP0V32C6L) is a cytostatic agent critical for the prevention of organ transplant rejection [1].
T80020	UDP-3-O-acyl-GlcNAc diammonium	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite
	UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1].		Endogenous Metabolite
T74191	Tanshinol borneol ester
	Tanshinol borneol ester, an angiogenesis stimulator, enhances several critical phases of angiogenesis via the Akt and MAPK signaling pathways. This compound also exhibits anti-ischemic and anti-atherosclerosis properties...
T73812	Phosphatidylinositol 4,5-bisphosphate
	Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), serving as a critical phospholipid in cell membranes, functions as a substrate for both phospholipase C (PLC) and phosphoinositide 3-...
T73073	PTP1B-IN-21
	PTP1B-IN-21 is a compound that functions as a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 μM), demonstrating a marked preference over the structurally similar T-cell protein tyrosine phosphat...

天然物製品

Pulsatilla saponin D

T3909

Synonym: Hederacolchiside A,SB365

Target: Apoptosis, Others

Jatrorrhizine chloride

T4912

Synonym: Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Target: Chloride channel, Antibacterial

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

Pentagalloylglucose

T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose

Target: Influenza Virus

UDP-3-O-acyl-GlcNAc diammonium

T80020

Synonym: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium

Target: Endogenous Metabolite

Tanshinol borneol ester

T74191

Synonym:

Target:

Phosphatidylinositol 4,5-bisphosphate

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate comp...
TMPH-00007	HMGCR Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol ...
TMPY-05822	Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)	HBV-D	E. coli
	Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPH-02837	PLXDC1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Plays a critical role in endothelial cell capillary morphogenesis.
TMPH-02836	PLXDC1 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.3 kDa ...
TMPK-00509	E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelia...
TMPY-00611	UBE2B Protein, Mouse, Recombinant	Mouse	E. coli
	The ubiquitin-conjugating enzyme E2B (Ube2b) is a critical target gene of androgen receptor (AR), mediating the function of AR in spermatogenesis by promoting H2A ubiquitylation. Moreover, UBE2B plays an important role i...
TMPH-00722	PykF Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis.
TMPK-00698	AGR2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progressi...
TMPH-03017	CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	Baculovirus Insect Cells
	Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethy...
TMPK-01468	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPH-01653	MLANA Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ...
TMPH-03447	ERG11 Protein, S. cerevisiae, Recombinant (GST)	Saccharomyces cerevisiae	E. coli
	Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. ERG11 Protein, S. cerevisiae, Recombinant (GST) is e...
TMPY-05160	PFKP Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPK-01469	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-00895	Tubby Protein, Human, Recombinant (His)	Human	E. coli
	Tubby is the founding member of the tubby-like family of proteins. Tubby-like proteins (TLPs) possess a highly conserved closed β barrel tubby domain at C-terminal and N-terminal F-box.Tubby plays a critical role in traf...
TMPH-00665	RecG Protein, E. coli O157:H7, Recombinant (His & SUMO)	E. coli	E. coli
	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to ...
TMPH-01652	MLANA Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ...
TMPH-02313	RPGR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integ...
TMPH-00325	S-layer Protein, Campylobacter fetus, Recombinant (His & Myc)	Campylobacter fetus	E. coli
	The S-layer is a paracrystalline mono-layered assembly of proteins which coats the surface of bacteria. This protein is critical for virulence. S-layer Protein, Campylobacter fetus, Recombinant (His & Myc) is expressed i...
TMPY-04764	PCK2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol...
TMPH-02476	HMGCR Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol ...
TMPK-00480	IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL...
TMPK-00661	IL-22 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPH-03751	CYBB Protein, Human, Recombinant (His)	Human	E. coli
	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr...
TMPK-00417	MERTK/Mer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mu...
TMPH-01895	POU5F1 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, F...
TMPJ-01132	NEDD8 Protein, Human, Recombinant	Human	E. coli
	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recrui...
TMPK-00520	PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system...
TMPJ-01146	LGALSL Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LG...
TMPK-01201	BPIFA1/LUNX Protein, Human, Recombinant	Human	E. coli
	Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submu...
TMPK-00820	AREG Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic ca...
TMPK-01202	CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated	Human	HEK293 Cells
	CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperrespons...
TMPH-00867	ADAMTS4 Protein, Human, Recombinant (GST)	Human	E. coli
	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neu...
TMPK-01194	IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	E. coli
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPH-01536	ITGB4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG...
TMPK-00418	MERTK/Mer Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mu...
TMPK-00768	ANXA1 Protein, Human, Recombinant (His)	Human	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-00948	CDH17 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00952	CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01224	CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPH-02134	U2AF1 Protein, Human, Recombinant (GST)	Human	E. coli
	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the b...
TMPK-00045	SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated	Human	HEK293 Cells
	The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal f...
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Cap8A Protein, S. aureus, Recombinant (His)

TMPH-03526

Species: Staphylococcus aureus

Expression System: E. coli

HMGCR Protein, Human, Recombinant (His)

TMPH-00007

Species: Human

Expression System: E. coli

Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)

TMPY-05822

Species: HBV-D

Expression System: E. coli

Fas Ligand Protein, Human, Recombinant (His)

TMPY-03956

Species: Human

Expression System: P. pastoris (Yeast)

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus Insect Cells

IL-7 Protein, Mouse, Recombinant (His)

TMPJ-00038

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

MMP-12 Protein, Human, Recombinant (catalytic domain)

TMPY-02869

Species: Human

Expression System: E. coli

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293 Cells

PLXDC1 Protein, Mouse, Recombinant (His)

TMPH-02837

Species: Mouse

Expression System: P. pastoris (Yeast)

PLXDC1 Protein, Mouse, Recombinant (E. coli, His)

TMPH-02836

Species: Mouse

Expression System: E. coli

E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)

TMPK-00509

Species: Cynomolgus

Expression System: HEK293 Cells

UBE2B Protein, Mouse, Recombinant

TMPY-00611

Species: Mouse

Expression System: E. coli

PykF Protein, E. coli, Recombinant (His)

TMPH-00722

Species: E. coli

Expression System: E. coli

AGR2 Protein, Mouse, Recombinant (His)

TMPK-00698

Species: Mouse

Expression System: E. coli

CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

TMPH-03017

Species: Mycobacterium tuberculosis

Expression System: Baculovirus Insect Cells

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01468

Species: Human

Expression System: HEK293 Cells

MLANA Protein, Human, Recombinant (His)

TMPH-01653

Species: Human

Expression System: P. pastoris (Yeast)

ERG11 Protein, S. cerevisiae, Recombinant (GST)

TMPH-03447

Species: Saccharomyces cerevisiae

Expression System: E. coli

PFKP Protein, Human, Recombinant (His & GST)

TMPY-05160

Species: Human

Expression System: Baculovirus Insect Cells

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01469

Species: Human

Expression System: HEK293 Cells

Tubby Protein, Human, Recombinant (His)

TMPK-00895

Species: Human

Expression System: E. coli

RecG Protein, E. coli O157:H7, Recombinant (His & SUMO)

TMPH-00665

Species: E. coli

Expression System: E. coli

MLANA Protein, Human, Recombinant (B2M & His)

TMPH-01652

Species: Human

Expression System: E. coli

RPGR Protein, Human, Recombinant (hFc)

TMPH-02313

Species: Human

Expression System: HEK293 Cells

S-layer Protein, Campylobacter fetus, Recombinant (His & Myc)

TMPH-00325

Species: Campylobacter fetus

Expression System: E. coli

PCK2 Protein, Human, Recombinant (His & GST)

TMPY-04764

Species: Human

Expression System: Baculovirus Insect Cells

HMGCR Protein, Mouse, Recombinant (His)

TMPH-02476

Species: Mouse

Expression System: E. coli

IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

TMPK-00480

Species: Cynomolgus

Expression System: HEK293 Cells

IL-22 Protein, Cynomolgus, Recombinant (His)

TMPK-00661

Species: Cynomolgus

Expression System: HEK293 Cells

CYBB Protein, Human, Recombinant (His)

TMPH-03751

Species: Human

Expression System: E. coli

MERTK/Mer Protein, Human, Recombinant (His)

TMPK-00417

Species: Human

Expression System: HEK293 Cells

POU5F1 Protein, Human, Recombinant (B2M & His)

TMPH-01895

Species: Human

Expression System: E. coli

NEDD8 Protein, Human, Recombinant

TMPJ-01132

Species: Human

Expression System: E. coli

PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)

TMPK-00520

Species: Cynomolgus

Expression System: HEK293 Cells

LGALSL Protein, Human, Recombinant (His)

TMPJ-01146

Species: Human

Expression System: E. coli

BPIFA1/LUNX Protein, Human, Recombinant

TMPK-01201

Species: Human

Expression System: E. coli

AREG Protein, Human, Recombinant (hFc)

TMPK-00820

Species: Human

Expression System: HEK293 Cells

CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated

TMPK-01202

Species: Human

Expression System: HEK293 Cells

ADAMTS4 Protein, Human, Recombinant (GST)

TMPH-00867

Species: Human

Expression System: E. coli

IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-01194

Species: Mouse

Expression System: E. coli

ITGB4 Protein, Human, Recombinant (His & Myc)

TMPH-01536

Species: Human

Expression System: E. coli

MERTK/Mer Protein, Human, Recombinant (mFc)

TMPK-00418

Species: Human

Expression System: HEK293 Cells

ANXA1 Protein, Human, Recombinant (His)

TMPK-00768

Species: Human

Expression System: E. coli

CDH17 Protein, Human, Recombinant (hFc)

TMPK-00948

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)

TMPK-00952

Species: Human

Expression System: HEK293 Cells

CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

TMPK-01224

Species: Mouse

Expression System: HEK293 Cells

U2AF1 Protein, Human, Recombinant (GST)

TMPH-02134

Species: Human

Expression System: E. coli

SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated

TMPK-00045

Species: Human

Expression System: HEK293 Cells

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カタログ番号	製品名
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L4520	Anti-Bacterial Compound Library	904 compounds
	A unique collection of 904 antibacterial bioactive compounds, a powerful tool for antibacterial drug development;
L2400	Endocrinology-Hormone Compound Library	784 compounds
	A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L5900	CNS-Penetrant Compound Library	509 compounds
	A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);
L2600	Neuronal Signaling Compound Library	2540 compounds
	A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L7900	Osteogenesis Compound Library	317 compounds
	A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;
L4300	Wnt/Hedgehog/Notch Compound Library	237 compounds
	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L2540	Gut Microbial Metabolite Library	614 compounds
	A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS;
L2510	Lipid Metabolism Compound Library	492 compounds
	A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L2630	Neuronal Differentiation Compound Library	672 compounds