lignan | TargetMol

カタログ番号	製品名	ターゲット
T13863	(rel)-Myrislignan	Others
	(rel)-Myrislignan, a lignan compound with a relative configuration, has been isolated from Myristica fragrans Houtt.
T125753	Saurulignan A
	Saurulignan A is a useful organic compound for research related to life sciences. The catalog number is T125753 and the CAS number is 1532522-50-1.
T125684	Maceneolignan B
	Maceneolignan B is a useful organic compound for research related to life sciences and the catalog number is T125684.
T126289	Dimethylwulignan A1
	Dimethylwulignan A1 is a useful organic compound for research related to life sciences and the catalog number is T126289.
T125420	Rehmaneolignan A
	Rehmaneolignan A is a useful organic compound for research related to life sciences. The catalog number is T125420 and the CAS number is 2001061-00-1.
T124524	Brassilignan
	Brassilignan is a useful organic compound for research related to life sciences. The catalog number is T124524 and the CAS number is 62624-76-4.
T125318	Curlignan
	Curlignan is a useful organic compound for research related to life sciences and the catalog number is T125318.
T125512	Ceplignan
	Ceplignan is a useful organic compound for research related to life sciences and the catalog number is T125512.
T8772	Sumaresinolic Acid	Others
	Sumaresinolic Acid is a natural lignan found in a variety of plants such as flaxseed, sesame and wheat bran and is a secondary metabolite of plants. It has been widely studied for its potential health benefits, including...
T34258	Ramontoside
	Ramontoside belongs to the class of organic compounds known as lignan glycosides.

カタログ番号	製品名	別名	ターゲット
TN2508	1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan		Others
	1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan is a natural product for research related to life sciences. The catalog number is TN2508 and the CAS number is 67920-48-3.		Others
T25562	Justicidin D	Neojusticin A,Neojusticin,Lignan J1
	Justicidin D is a lignan that has antiviral activities.
TN1610	Epimagnolin A		Parasite
	Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.		Parasite
T3866	Macelignan	Anwuligan,(+)-Anwulignan	Others , COX
	Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.		Others , COX
TN2071	Picropodophyllone	(-)-Picropodophyllone,Picropodopyllotoxone	Others
	Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.		Others
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
TN1390	Angeloylgomisin Q		Others
	Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL.		Others
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
TN2062	Phyllanthin		NF-κB
	Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.		NF-κB
T5S1923	Schisandrin C	Schizandrin-C,Wuweizisu-C	Apoptosis , Others , Virus Protease
	Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.		Apoptosis , Others , Virus Protease
T2950	Schisandrin	Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol	Autophagy
	Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.		Autophagy
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T4S1540	Myrislignan		Apoptosis , NF-κB
	Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...		Apoptosis , NF-κB
T81997	Kadsulignan C
	Kadsulignan C is a spirobenzofuranoid dibenzocyclooctadiene lignan isolated from Kadsura oblongifolia [1].
T79952	Kadsuralignan A
	Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an effective concentration (EC50) of 2.23 μg/mL [1].
T79954	Kadsulignan H		NO Synthase
	Kadsulignan H (compound 13), a lignan, exhibits inhibitory activity on nitric oxide (NO) production, presenting an IC50 value of 14.1 μM in BV-2 cells [1].		NO Synthase
T75499	Maceneolignan H
	Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1].
T79977	Maceneolignan A
	Maceneolignan A, a natural product isolated from the aril of Myristica fragrans (Myristicaceae), inhibits β-hexosaminidase release in RBL-2H3 cells, exhibiting an IC50 of 48.4 μM. Additionally, it suppresses TNF-α releas...
TN3822	Demethylcarolignan E		Others
	Demethylcarolignan E is a natural product from Hibiscus taiwanensis.		Others
TN6302	Illiciumlignan D
	Illiciumlignan D is a natural product for research related to life sciences. The catalog number is TN6302 and the CAS number is 2237239-36-8.
TN4363	Kadsulignan N		Others
	Kadsulignan N is a natural product of Kadsura, Schisandraceae. The catalog number is TN4363 and the CAS number is 163564-58-7. Kadsulignan N can be used as a reference standard.		Others
TN3007	4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan		Others
	4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan shows cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).		Others
TN6353	Ananolignan L
	Ananolignan L is a natural product for research related to life sciences. The catalog number is TN6353 and the CAS number is 1280213-70-8.
T72236	Erythro-Austrobailignan-6
	Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.
TN5420	3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
	3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan is a natural product for research related to life sciences. The catalog number is TN5420 and the CAS number is 873867-94-8.
TN1904	Magnolignan C		Others
	Magnolignan C is a natural product from Magnolia officinalis.		Others
TN1903	Magnolignan A		Others
	Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively.		Others
TN1165	(Rac)-Myrislignan	1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol,rac-myrislignan	Others
	1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the min...		Others
TN3018	4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan		Others
	4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan is a natural product for research related to life sciences. The catalog number is TN3018 and the CAS number is 144881-21-0.		Others
TN6406	Sphenanlignan
	Sphenanlignan is a natural product of Schisandra, Schisandraceae. The catalog number is TN6406 and the CAS number is 866347-36-6. Sphenanlignan can be used as a reference standard.
TN5430	Pomegralignan
	Pomegralignan is a natural product for research related to life sciences. The catalog number is TN5430 and the CAS number is 1562492-32-3.
TN5194	Tupichilignan A		Others
	Tupichilignan A is a natural product for research related to life sciences. The catalog number is TN5194 and the CAS number is 69586-96-5.		Others
TN5411	4,9,9'-Trihydroxy-3,3'-dimethoxy-8,4'-oxyneolignan
	4,9,9'-Trihydroxy-3,3'-dimethoxy-8,4'-oxyneolignan is a natural product for research related to life sciences. The catalog number is TN5411 and the CAS number is 53505-68-3.
TN2311	Wulignan A1		Antifection
	Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.		Antifection
T32745	Liconeolignan
	Liconeolignan is extracted from the root of Glycyrrhiza uralensis.
TN1815	Kadsulignan L		HBV , PAFR
	Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.		HBV , PAFR
TN4673	(+)-Nortrachelogenin	Wikstromol	Apoptosis , HIV Protease , PI3K , Antifection
	(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.		Apoptosis , HIV Protease , PI3K , Antifection
T2919	Sesamin	Fagarol,Fsesamin	Others
	Sesamin (Fsesamin) is a lignan extracted from Sesamum indicum L.		Others
TN1355	Acanthoside B		Immunology/Inflammation related
	Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.		Immunology/Inflammation related
T5691	Paulownin		Anti-infection
	Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.		Anti-infection
TN1116	Schisandrone	Arisantetralone C	Beta Amyloid , NOS , NF-κB
	Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.		Beta Amyloid , NOS , NF-κB
T83321	4-Demethyldeoxypodophyllotoxin		Chk
	4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.		Chk
T2S0531	Pinoresinol dimethyl ether	(+)-Eudesmin	Others , PKC
	Pinoresinol dimethyl ether, a non-phenolic furan lignan isolated from the bark of Magnolia kobus, exhibits neuroactivity. It stimulates upstream MAPK, PKC, and PKA pathways, inducing neurite outgrowth in PC12 cells.		Others , PKC
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside	(+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others
	(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia. It exhibits antioxidative, antihypertensive activities, and acts as an inhibitor of cyclic adenosine monophosp...		Others
T2913	Schisantherin A	Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K	NF-κB
	Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.		NF-κB
TN4674	Nortrachelogenin-8'-O-beta-glucoside		Others
	Nortrachelogenin-8'-O-beta-glucoside is a lignan with a diarylhydroxybutyrolactone skeleton which isolated from the leaves and stems of Trachelospermum jasminoides (Lindl.) Lem.		Others
T5S0483	(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside	(-)-Syringaresnol-4-O-beta-D-apiofuranos	Others
	(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycosides from the bark of Albizzia myriophylla.		Others
T2957	Arctigenin	(-)-Arctigenin	Apoptosis , MMP , Influenza Virus , Autophagy
	(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plan...		Apoptosis , MMP , Influenza Virus , Autophagy
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
TN4171	Grossamide		NO Synthase
	Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) i...		NO Synthase
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