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Search Results for " proton "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T23079	NPE-caged-proton		Others
	Generates rapid acidifications down to pH 2		Others
T17030	Tegoprazan		ATPase , Proton pump
	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...		ATPase , Proton pump
T4701	Diclofop-methyl		Others
	Diclofop-methyl is used as the active ingredient in many herbicides that are used to control weed growth in plants such as wheat and wild oats.		Others
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
T22391	Omeprazole Sodium		P450 , Proton pump , Antibacterial , Autophagy
	Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive...		P450 , Proton pump , Antibacterial , Autophagy
T11191	EN6		Proton pump , Autophagy
	EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP-43 aggregates, a causative ...		Proton pump , Autophagy
T2188	Thonzonium Bromide		Proton pump , Antibacterial , Autophagy
	Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteocl...		Proton pump , Antibacterial , Autophagy
T10435	Linaprazan	AZD0865	Potassium Channel
			Potassium Channel
T16682	Pumaprazole	BY-841	Proton pump
	Pumaprazole (BY-841) is an antagonist of a reversible proton pump.		Proton pump
T8388	Vonoprazan	TAK-438 (free base)	Proton pump
	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis		Proton pump
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T9230	KM 91104		ATPase
	KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.		ATPase
T0502	Zinc pyrithione	OM-1563	Proton pump , Antibacterial , Antifungal
	Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.		Proton pump , Antibacterial , Antifungal
T1651	Rabeprazole sodium	Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium	Apoptosis , Proton pump
	Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch...		Apoptosis , Proton pump
T6700	Tenatoprazole	TU-199	Proton pump
	Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).		Proton pump
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T1734	Rabeprazole Sulfide	Rabeprazole Related Compound E	Proton pump , Antibacterial
	Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.		Proton pump , Antibacterial
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T0757	Omeprazole	Losec,Prilosec,H 16868,Antra	Proton pump , Phospholipase , Antibacterial , Autophagy
	Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).		Proton pump , Phospholipase , Antibacterial , Autophagy
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T1021	(R)-Lansoprazole	Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole	Proton pump
	(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutra...		Proton pump
T0674	Lansoprazole	A-65006,AG-1749	Proton pump , Phospholipase , Antibacterial
	Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...		Proton pump , Phospholipase , Antibacterial
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T71812	Protonstatin-1
	Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
T6379	AMG 517	AMG517,AMG-517	TRP/TRPV Channel
	AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.		TRP/TRPV Channel
T29164	WY-47766	WY47766
	WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.
T5449	Bamaquimast	L 0042,F 10126	Proton pump
	Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.		Proton pump
T28665	Saviprazole	Hoe731,Hoe 731,Hoe-731	Proton pump
	Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.		Proton pump
T2687	Omeprazole sulfide	Omeprazole metabolite Omeprazole sulfide,Ufiprazole	Proton pump , Drug Metabolite
	Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.		Proton pump , Drug Metabolite
T12309	Omeprazole metabolite Omeprazole sulfone	Omeprazole sulphone,Omeprazole sulfone	Others
	Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.		Others
T23667	AGN-201904	AGN201904,AGN 201904	ATPase
	AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers.		ATPase
T20110	Ethylene thiourea	ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372	Others
	Ethylene thiourea (NCIC03372) is a pesticide used in fruit and vegetable production. Ethylene thiourea is also used as a novel contrast agent for MRI studies based on proton chemical exchange-dependent saturation transfe...		Others
T6834	FCCP	Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone	ATPase , Mitochondrial Metabolism
	FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is often used as an apoptosis inducer.		ATPase , Mitochondrial Metabolism
T0961	Trometamol	Tromethamine	COX
	Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostagland...		COX
T18957	D-Ala-Lys-AMCA hydrochloride		Others
	D-Ala-Lys-AMCA hydrochloride is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into Caco-2 cells and liver cancer cell...		Others
T21023	Bedaquiline fumarate	TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323	Antibacterial , Antibiotic
	Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ...		Antibacterial , Antibiotic
T10138	4-Desmethoxy Omeprazole		Drug Metabolite
	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).		Drug Metabolite
T7081	CCCP	Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone	Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial
	CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ...
T9146	Ms48107	Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-	Others
	MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch...		Others
T7587	Tenapanor	RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722	Sodium Channel
	Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinica...		Sodium Channel
T20714	Levolansoprazole	(S)-Lansoprazole,(-)-Lansoprazole	Proton pump
	Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhibits acid formation in isolated canine parietal cells (IC50:...		Proton pump
T10221	Abeprazan hydrochloride	DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump
	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...		Proton pump
T28794	SKF-97574 HCl	SKF97574,SKF-97574,B-9937-051,BY 574,SKF 97574,SK&F-97574
	SKF-97574 is proton pump inhibitor.
T28787	SK&F-95601	SK&F 95601,SKF95601,SKF 95601,SKF-95601
	F-95601 is a proton pump inhibitor.
T11817	Lansoprazole Sulfide D4		Proton pump
	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.La...		Proton pump

Compounds

Target: ATPase, Proton pump

Target: Proton pump, Cysteine Protease

Omeprazole Sodium

T22391

Synonym:

Target: P450, Proton pump, Antibacterial, Autophagy

EN6

T11191

Synonym:

Target: Proton pump, Autophagy

Thonzonium Bromide

T2188

Synonym:

Target: Proton pump, Antibacterial, Autophagy

Linaprazan

T10435

Synonym: AZD0865

Target: Potassium Channel

Pumaprazole

T16682

Synonym: BY-841

Target: Proton pump

Vonoprazan

T8388

Synonym: TAK-438 (free base)

Target: Proton pump

Vonoprazan Fumarate

T21254

Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438

Target: Proton pump

Target: Proton pump, Antibacterial, Antifungal

Rabeprazole sodium

T1651

Synonym: Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium

Target: Apoptosis, Proton pump

Tenatoprazole

T6700

Synonym: TU-199

Target: Proton pump

Esomeprazole Sodium

T2686L

Synonym: (S)-Omeprazole sodium

Target: ATPase, Proton pump

Ilaprazole

T1756L

Synonym: IY81149,IY 81149,IY-81149

Target: Proton pump, TOPK

Rabeprazole Sulfide

T1734

Synonym: Rabeprazole Related Compound E

Target: Proton pump, Antibacterial

Ilaprazole sodium

T1756

Synonym: IY-81149 sodium

Target: Proton pump, TOPK

Omeprazole

T0757

Synonym: Losec,Prilosec,H 16868,Antra

Target: Proton pump, Phospholipase, Antibacterial, Autophagy

Esomeprazole Magnesium

T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

(R)-Lansoprazole

T1021

Synonym: Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole

Target: Proton pump

Lansoprazole

T0674

Synonym: A-65006,AG-1749

Target: Proton pump, Phospholipase, Antibacterial

Pantoprazole

T6928

Synonym: SKF96022,BY1023

Target: Apoptosis, Proton pump, Autophagy

Esomeprazole Magnesium trihydrate

T8386

Synonym: (S)-Omeprazole magnesium trihydrate

Target: Proton pump

Pantoprazole Sodium Hydrate

T0161

Synonym: SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)

Target: Apoptosis, Potassium Channel, Proton pump, Autophagy

Pantoprazole sodium

T6929

Synonym: Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc

Target: Apoptosis, Others, Proton pump, HIF, Autophagy

Amantadine hydrochloride

T1406

Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Synonym: AMG517,AMG-517

Target: TRP/TRPV Channel

Synonym: L 0042,F 10126

Target: Proton pump

Saviprazole

T28665

Synonym: Hoe731,Hoe 731,Hoe-731

Target: Proton pump

Omeprazole sulfide

T2687

Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole

Target: Proton pump, Drug Metabolite

Omeprazole metabolite Omeprazole sulfone

T12309

Synonym: Omeprazole sulphone,Omeprazole sulfone

Target: Others

AGN-201904

T23667

Synonym: AGN201904,AGN 201904

Target: ATPase

Ethylene thiourea

T20110

Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372

Target: Others

FCCP

T6834

Synonym: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone

Target: ATPase, Mitochondrial Metabolism

Trometamol

T0961

Synonym: Tromethamine

Target: COX

D-Ala-Lys-AMCA hydrochloride

Synonym: TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323

Target: Antibacterial, Antibiotic

4-Desmethoxy Omeprazole

T10138

Synonym:

Target: Drug Metabolite

CCCP

T7081

Synonym: Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone

Target: Apoptosis, IκB/IKK, COX, Mitochondrial Metabolism, STING, IFNAR, Antibacterial

ms48107

T9146

Synonym: Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-

Target: Others

Tenapanor

T7587

Synonym: RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722

Target: Sodium Channel

Levolansoprazole

T20714

Synonym: (S)-Lansoprazole,(-)-Lansoprazole

Target: Proton pump

Abeprazan hydrochloride

T10221

Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride

Target: Proton pump

SKF-97574 HCl

T28794

Synonym: SKF97574,SKF-97574,B-9937-051,BY 574,SKF 97574,SK&F-97574

Target:

SK&F-95601

T28787

Synonym: SK&F 95601,SKF95601,SKF 95601,SKF-95601

Target:

Lansoprazole Sulfide D4

T11817

Synonym:

Target: Proton pump

カタログ番号	製品名	別名	ターゲット
TQ0184	Chebulinic acid		ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
T6740	Bafilomycin A1		Apoptosis , Proton pump , Antibacterial , Antibiotic , Autophagy
	Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autopha...
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
T75677	Protoneogracillin
	Protoneogracillin, a furostanol glycoside, demonstrates anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and exhibits cytotoxic activity against K562 cancer cells (IC 50 =6.6 μM) [1] [2].
T21651	Lansoprazole sodium	Lansoprazole (sodium), AG-1749 sodium	Proton pump , Phospholipase , Antibacterial
	Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease.		Proton pump , Phospholipase , Antibacterial
T10023	1-Naphthol	NSC 9586,Nako TRB,Furro ER	Endogenous Metabolite
	1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media.		Endogenous Metabolite
T4927	4-Guanidinobutanoic acid	4-GBA,4-Guanidinobutyric acid	Endogenous Metabolite
	4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid transporters hPAT1.		Endogenous Metabolite
T2910	Flavonol	3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone	Others , Endogenous Metabolite
	Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone...		Others , Endogenous Metabolite
T12313	Ophiobolin B		Others
	Ophiobolin B is a sesterterpene Helminthosporium oryzae metabolite, inhibits proton extrusion from maize coleoptiles.		Others
TN3135	5-O-Methylnaringenin		Others
	5-O-Methylnaringenin is a marker, reduced MS detection of 5-O-methylnaringenin indicated that nifedipine may preferably remove a proton from the 5-position OH group in the A ring of the flavonoid skeleton.		Others

天然物製品

Chebulinic acid

TQ0184

Synonym:

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Diphyllin

TN1103

Synonym:

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Bafilomycin A1

T6740

Synonym:

Target: Apoptosis, Proton pump, Antibacterial, Antibiotic, Autophagy

Abscisic Acid

T6368

Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）

Target: Others, Proton pump, Endogenous Metabolite

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Synonym: Lansoprazole (sodium), AG-1749 sodium

Target: Proton pump, Phospholipase, Antibacterial

1-Naphthol

T10023

Synonym: NSC 9586,Nako TRB,Furro ER

Target: Endogenous Metabolite

4-Guanidinobutanoic acid

T4927

Synonym: 4-GBA,4-Guanidinobutyric acid

Target: Endogenous Metabolite

Flavonol

T2910

Synonym: 3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01892	ATP4A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is P20648.
TMPH-02310	ATP6V0D1 Protein, Human, Recombinant (GST)	Human	E. coli
	ATP6V0D1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 67.3 kDa and the accession number is P61421.
TMPH-01893	ATP4B Protein, Human, Recombinant (GST)	Human	E. coli
	ATP4B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 53.6 kDa and the accession number is P51164.
TMPH-01894	ATP4B Protein, Human, Recombinant	Human	E. coli
	ATP4B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.6 kDa and the accession number is P51164.
TMPH-00964	ATP5PB Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00785	Bacteriorhodopsin Protein, Halobacterium halobium, Recombinant (His & Myc & SUMO)	Halobacterium halobium	E. coli
	Light-driven proton pump.
TMPH-02530	ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator...
TMPY-03609	ATP5D Protein, Human, Recombinant (His)	Human	E. coli
	ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth...
TMPY-03511	COX5B Protein, Human, Recombinant (His)	Human	E. coli
	Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contribut...
TMPH-01696	SLC16A4 Protein, Human, Recombinant (His)	Human	E. coli
	Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine...
TMPH-03259	Carbonic Anhydrase 2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide abso...
TMPH-03751	CYBB Protein, Human, Recombinant (His)	Human	E. coli
	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr...
TMPH-00645	Lactose permease Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D-galactopyranoside (TM...
TMPH-00627	GAD-alpha Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions...
TMPH-01744	NOX1 Protein, Human, Recombinant (His)	Human	E. coli
	NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-d...
TMPJ-01106	NAD(P) transhydrogenase/NNT Protein, Human, Recombinant (His)	Human	E. coli
	NAD(P)+transhydrogenase (NNT) is located in the inner mitochondrial membrane and catalyzes a reversible hydride transfer between NAD(H) and NADP(H) that is coupled to proton translocation between the intermembrane space ...
TMPH-02347	Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th...
TMPH-02348	Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th...
TMPY-01761	Carbonic Anhydrase 3 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including re...