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Search Results for " pyrimidine "

ターゲット

397

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T1696	2-(1-Piperazinyl)pyrimidine		Adrenergic Receptor
	2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug.		Adrenergic Receptor
T2075	Pyrazolo[1,5-a]pyrimidine 4h		Others
	Pyrazolo[1,5-a]pyrimidine 4h is a morpholine derivative that is a selective antagonist of the adenosine A2A receptor. It has been shown to be neuroprotective in animal models of Parkinson's disease and Huntington's chore...		Others
T50078	2-(pentylsulfanyl)pyrimidine-4,6-diol		GPR
	2-(pentylsulfanyl)pyrimidine-4,6-diol is a novel GRP84 agonist.		GPR
T7256	4-Chlorothieno[3,2-d]pyrimidine
	4-Chlorothieno[3,2-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T7256 and the CAS number is 16269-66-2.
T7451	2-Cyanopyrimidine	2-cyano-Pyrimidine	Cysteine Protease
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)		Cysteine Protease
T9366	Pyrazoloadenine	4-Aminopyrazolo[3,4-d]pyrimidine	ROS
	Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.		ROS
T8621	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE		Others
	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.		Others
T8613	1-Ethyl-6-aminouracil	6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE	Adenosine Receptor
	1-Ethyl-6-aminouracil (6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE) is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenosine A2B receptors.		Adenosine Receptor
T50079	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine		Others
	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine can be used in the development of new deoxycytidine kinase (dCK) inhibitors.		Others
T9945	MNK8	3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].		STAT
T24639	PIH	pyrimidine-indole hybrid
	PIH is a ciliogenesis inhibitor by microtubule destabilization that acts by antagonizing Hh signaling by repressing cilia biogenesis and disassembly of alpha-tubulin in its stabilized form.
T16922	SPOP-IN-6b	2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide	Others
	SPOP-IN-6b is an effective inhibitor of speckle-type POZ protein (SPOP) with an IC50 of 3.58 μM and can be used in stuides about the treatment of renal cancer.		Others
T2476	INCB032304	4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine	Others
	INCB032304 is an important pharmaceutical intermediate. It can be used in the preparation of Ruxolitinib phosphate (I008849), a janus kinase inhibitor, and in the preparation of Barretinib.		Others
T13017	STL127705	Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	DNA-PK , Others
	STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.		DNA-PK , Others
T67762	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid		Others
	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid belonging to the pyrimidine family, which has been shown to have anti-inflammatory, anticonvulsant and antitumor properties.		Others
T67877	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid		Others
	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid is commonly used to synthesize compounds with anticancer and antitumor properties.		Others
T9048	Ecamsule		Others
	Ecamsule is a benzylidene camphor derivative, many of which are known for their excellent photostability. It can be added to many sunscreens to filter out UVA rays.		Others
T2161	Cardiogenol C		Wnt/beta-catenin
	Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.		Wnt/beta-catenin
T4348	Syk Inhibitor II		5-HT Receptor , Syk
	Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).		5-HT Receptor , Syk
T36870	5,6-dihydro-5-Fluorouracil	5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione	Others
	5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.		Others
T66446	2-(Propylthio)pyrimidine-4,6-diol
	2-(Propylthio)pyrimidine-4,6-diol is a useful organic compound for research related to life sciences. The catalog number is T66446 and the CAS number is 145783-12-6.
T64428	4,6-Dichloro-2-(propylthio)pyrimidine
	4,6-Dichloro-2-(propylthio)pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T64428 and the CAS number is 1401318-10-2.
T16911	Sorivudine	BV-araU	DNA/RNA Synthesis
	Sorivudine (BV-araU) has antiviral activity against several viruses including varicella zoster virus, herpes simplex type 1 virus, and Epstein-Barr virus by interfering with viral DNA synthesis.		DNA/RNA Synthesis
T66608	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T66608 and the CAS number is 90213-66-4.
TNU1019	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
T66488	6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione
	6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66488 and the CAS number is 18592-13-7.
TNU0659	4-Chloro-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound-purine, intermediate and building block-electrophile, nucleoside base
TNU1018	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine
	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
T66602	4-Chloro-5H-pyrrolo[3,2-d] pyrimidine
	4-Chloro-5H-pyrrolo[3,2-d] pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T66602 and the CAS number is 84905-80-6.
T66222	4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine
	4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T66222 and the CAS number is 145783-14-8.
T5168	EGFR-IN-12	EGFR Inhibitor	Apoptosis , EGFR
	EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.		Apoptosis , EGFR
T64959	Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
	Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T64959 and the CAS number is 5909-24-0.
T64808	5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine
	5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine is a useful organic compound for research related to life sciences. The catalog number is T64808 and the CAS number is 16285-82-8.
T64531	2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine
	2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T64531 and the CAS number is 84746-24-7.
T66943	5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione
	5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66943 and the CAS number is 73742-45-7.
T65517	4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
	4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T65517 and the CAS number is 479633-63-1.
TNU0611	4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound –purines, intermediate and building block; Used for modified nucleosides and nucleic acids
T65530	4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
	4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T65530 and the CAS number is 16372-08-0.
TNU0717	4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
	Heterocyclic compound - purine; Intermediate and building blocks– electrophile and nucleophile; Nucleoside base
T66583	Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
	Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66583 and the CAS number is 211230-35-2.
TNU1478	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid
	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid is a PNA-related Derivative; Heterocyclic Compound - Fused polyheterocycle.
TNU1020	6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
	6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0323	4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 7-deaza-8-aza purine nucleoside.
TNU1015	4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine
	4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1032	7-(2-Deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
	Nucleoside Derivatives - 7-Deaza-purine nucleosides; 6-De-aminopurine nucleosides
TNU0280	4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside; 2-Modified purine nucleoside
T66523	4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
	4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T66523.
T66433	Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
	Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66433 and the CAS number is 330785-81-4.
T9309	MTOR inhibitor 11
	mTOR inhibitor 11 is a useful organic compound for research related to life sciences. The catalog number is T9309 and the CAS number is 1195785-35-3.
TNU1477	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester
	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester is a useful organic compound for research related to life sciences and the catalog number is TNU1477.

Compounds

2-(1-Piperazinyl)pyrimidine

T1696

Synonym:

Target: Adrenergic Receptor

Pyrazolo[1,5-a]pyrimidine 4h

T2075

Synonym:

Target: Others

2-(pentylsulfanyl)pyrimidine-4,6-diol

T50078

Synonym:

Target: GPR

4-Chlorothieno[3,2-d]pyrimidine

Synonym: 2-cyano-Pyrimidine

Target: Cysteine Protease

Pyrazoloadenine

T9366

Synonym: 4-Aminopyrazolo[3,4-d]pyrimidine

Target: ROS

ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE

T8621

Synonym:

Target: Others

1-Ethyl-6-aminouracil

T8613

Synonym: 6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE

Target: Adenosine Receptor

2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine

Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

Target: STAT

PIH

T24639

Synonym: pyrimidine-indole hybrid

Target:

SPOP-IN-6b

T16922

Synonym: 2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

Target: Others

INCB032304

T2476

Synonym: 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine

Target: Others

STL127705

T13017

Synonym: Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione

Target: DNA-PK, Others

2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid

T67762

Synonym:

Target: Others

2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid

Target: Wnt/beta-catenin

Syk Inhibitor II

T4348

Synonym:

Target: 5-HT Receptor, Syk

5,6-dihydro-5-Fluorouracil

T36870

Synonym: 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione

Target: Others

2-(Propylthio)pyrimidine-4,6-diol

T66446

Synonym:

Target:

4,6-Dichloro-2-(propylthio)pyrimidine

Target: DNA/RNA Synthesis

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

T66608

Synonym:

Target:

6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine

TNU1019

Synonym:

Target:

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione

T66488

Synonym:

Target:

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine

TNU0659

Synonym:

Target:

6-Amino-4-chloropyrazolo[3,4-d]pyrimidine

TNU1018

Synonym:

Target:

4-Chloro-5H-pyrrolo[3,2-d] pyrimidine

T66602

Synonym:

Target:

4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine

Synonym: EGFR Inhibitor

Target: Apoptosis, EGFR

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

T64959

Synonym:

Target:

5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine

T64808

Synonym:

Target:

2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine

T64531

Synonym:

Target:

5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione

T66943

Synonym:

Target:

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

T65517

Synonym:

Target:

4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

TNU0611

Synonym:

Target:

4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

T65530

Synonym:

Target:

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine

TNU0717

Synonym:

Target:

Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

T66583

Synonym:

Target:

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid

TNU1478

Synonym:

Target:

6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

TNU1020

Synonym:

Target:

4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

TNU0323

Synonym:

Target:

4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine

TNU1015

Synonym:

Target:

7-(2-Deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

TNU1032

Synonym:

Target:

4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

TNU0280

Synonym:

Target:

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid

T66523

Synonym:

Target:

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester

TNU1477

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T4809	Pyrimidine	Metadiazine	Others , Endogenous Metabolite
	Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...		Others , Endogenous Metabolite
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite
TN7191	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine	5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Others
	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) is a marine derived natural products found in Echinodictyum sp.		Others
T5078	Orotic acid monohydrate	2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate	Others , Endogenous Metabolite
	Orotic acid monohydrate is an intermediate product in pyrimidine metabolism.		Others , Endogenous Metabolite
T7520	Deoxycytidine triphosphate		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
	Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T0746	Orotic acid	Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite
	Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T3271	Orotic acid zinc	Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
T4711	2,4-Dihydroxypyrimidine-5-carboxylic acid	Isoorotic acid,Uracil-5-carboxylic acid	Others , Endogenous Metabolite
	2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. 2,4-Dihydroxypyrimidine-5-carboxylic acid has been used to synthesize N1-al...		Others , Endogenous Metabolite
T0986	Flucytosine	5-Fluorocytosine,Ro 2-9915,Fluorocytosine,NSC 103805	DNA/RNA Synthesis , Antibiotic , Antifungal
	Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.		DNA/RNA Synthesis , Antibiotic , Antifungal
T5284	N-Carbamoyl-DL-aspartic acid	N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid	Others , Endogenous Metabolite
	N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is an intermediary product in pyrimidine biosynthesis.		Others , Endogenous Metabolite
T4887	3-Amino-2-methylpropanoic acid	DL-3-AMINOISOBUTYRIC ACID,α-Methyl-β-alanine	Endogenous Metabolite
	3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 3.5.1.6), the last step in pyrimidine degradation. Be...		Endogenous Metabolite
TWO2759	Thymine	5-methyluracil	Others , Endogenous Metabolite
	One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine (5-methyluracil) is a pyrimidine nucleo...		Others , Endogenous Metabolite
T4831	α,α-Dimethylglycine	2-Aminoisobutyric acid,α-Aminoisobutanoic acid	Others , Endogenous Metabolite
	NSC-16590 (2-Aminoisobutyric acid) is a nonprotein amino acid (is an end product of pyrimidine Metabolism) excreted in the urine of about 5% of healthy individuals, and high excretion is an autosomal recessive phenotype.		Others , Endogenous Metabolite
T7457	5-Methyl-2'-deoxycytidine	5-Methyldeoxycytidine,5MedCyd	DNA Methyltransferase , Endogenous Metabolite
	5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.		DNA Methyltransferase , Endogenous Metabolite
T1591L	Cytidine	Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN...		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
TMA2440	Uridine 5'-monophosphate disodium salt	Disodium UMP,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucle...		Others
T5288	Cytidine-5'-triphosphate disodium	CTP,Cytidine 5'-triphosphate (disodium salt)	Others , Endogenous Metabolite
	Cytidine-5'-triphosphate disodium (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. Cytidine-5'-triphosphate disodium is used in the synthesis of RNA by RNA polymerases...		Others , Endogenous Metabolite
T4832	Cytosine	6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine	Endogenous Metabolite
	Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le...		Endogenous Metabolite
T0069	Uracil		Others , Endogenous Metabolite
	Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt...		Others , Endogenous Metabolite
T4919	Ureidopropionic acid	Carbamoyl-b-alanine,3-Ureidopropionic acid	Endogenous Metabolite
	Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further de...		Endogenous Metabolite
T4758	2'-Deoxycytidine	Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine	Endogenous Metabolite
	2'-Deoxycytidine (Deoxyribose cytidine) is one of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phos...		Endogenous Metabolite
T4880	L-Dihydroorotic acid		Others , Endogenous Metabolite
	L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell, L-dihydroorotic acid is primarily lo...		Others , Endogenous Metabolite
T39626	Orotidine 5′-monophosphate	Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate
	Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E. coli, and mouse processes. It serves as an intermediate in uridine monophosphate (UMP) biosynthesis and is utili...
T82682	Convicine
	Convicine, a pyrimidine glycoside found in faba beans [1] [2], serves as the precursor for the aglycones Divicine and Isouramil, alongside Vicine. It is a principal factor in favism, a genetic disorder that causes severe...
T75676	Orotidine 5′-monophosphate trisodium
	Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M. tuberculosis, S. cerevisiae, S. typhimurium, and P. falcipar...

天然物製品

Pyrimidine

T4809

Synonym: Metadiazine

Target: Others, Endogenous Metabolite

Purine

T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine

Target: Others, Endogenous Metabolite

4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine

TN7191

Synonym: 5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Target: Others

Orotic acid monohydrate

T5078

Synonym: 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate

Target: Others, Endogenous Metabolite

Deoxycytidine triphosphate

T7520

Synonym:

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Orotic acid

T0746

Synonym: Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Orotic acid zinc

T3271

Synonym: Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

2,4-Dihydroxypyrimidine-5-carboxylic acid

T4711

Synonym: Isoorotic acid,Uracil-5-carboxylic acid

Target: Others, Endogenous Metabolite

Flucytosine

T0986

Synonym: 5-Fluorocytosine,Ro 2-9915,Fluorocytosine,NSC 103805

Target: DNA/RNA Synthesis, Antibiotic, Antifungal

N-Carbamoyl-DL-aspartic acid

T5284

Synonym: N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid

Target: Others, Endogenous Metabolite

3-Amino-2-methylpropanoic acid

T4887

Synonym: DL-3-AMINOISOBUTYRIC ACID,α-Methyl-β-alanine

Target: Endogenous Metabolite

Thymine

TWO2759

Synonym: 5-methyluracil

Target: Others, Endogenous Metabolite

α,α-Dimethylglycine

T4831

Synonym: 2-Aminoisobutyric acid,α-Aminoisobutanoic acid

Target: Others, Endogenous Metabolite

5-Methyl-2'-deoxycytidine

T7457

Synonym: 5-Methyldeoxycytidine,5MedCyd

Target: DNA Methyltransferase, Endogenous Metabolite

Cytidine

T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Uridine 5'-monophosphate disodium salt

TMA2440

Synonym: Disodium UMP,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Target: Others

Cytidine-5'-triphosphate disodium

T5288

Synonym: CTP,Cytidine 5'-triphosphate (disodium salt)

Target: Others, Endogenous Metabolite

Cytosine

T4832

Synonym: 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine

Target: Endogenous Metabolite

Uracil

T0069

Synonym:

Target: Others, Endogenous Metabolite

Ureidopropionic acid

T4919

Synonym: Carbamoyl-b-alanine,3-Ureidopropionic acid

Target: Endogenous Metabolite

2'-Deoxycytidine

T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine

Target: Endogenous Metabolite

L-Dihydroorotic acid

T4880

Synonym:

Target: Others, Endogenous Metabolite

Orotidine 5′-monophosphate

T39626

Synonym: Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate

Orotidine 5′-monophosphate trisodium

T75676

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03855	DNase I Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos...
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re...
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. A...
TMPJ-01374	UPB1 Protein, Human, Recombinant (His)	Human	E. coli
	β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-U...
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPH-01779	RNASE2 Protein, Human, Recombinant (His)	Human	E. coli
	This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological...
TMPH-03614	DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO)	Synechococcus	E. coli
	Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the ...
TMPJ-01262	UPRT Protein, Human, Recombinant (His)	Human	E. coli
	UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o...
TMPJ-01207	UPP1 Protein, Human, Recombinant (His)	Human	E. coli
	Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in h...
TMPJ-00905	DTYMK Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis...
TMPY-03332	PRTFDC1 Protein, Human, Recombinant (His)	Human	E. coli
	PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ...
TMPY-03180	Ribonuclease A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RNase A, also known as ribonuclease A and RNASE1, belongs to ribonuclease A superfamily. It is a pancreatic-type of secretory ribonuclease. RNase A is a basic protein and its many positive charges are consistent with its...
TMPY-03457	ERH Protein, Human, Recombinant (His)	Human	E. coli
	ERH(enhancer of rudimentary homolog) belongs to the E(R) family. It is expressed in all tissues examined. The monomeric structure of ERH comprises a single domain consisting of three α-helices and four β-strands, which...
TMPH-01239	XPC Protein, Human, Recombinant (His)	Human	E. coli
	Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B an...