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Search Results for " sesquiterpene "

阻害剤

天然化合物

カタログ番号	製品名	別名
T71553	Ainsliadimer A
	Ainsliadimer A, a sesquiterpene lactone dimer from Ainsliaea macrocephala, has antitumour activity and induces cell death in various cancer cells.
T32576	Laserolide
	Laserolide is a sesquiterpene lactone.
T34933	Trichodesmic acid	(+)-Trichodesmic acid
	Trichodesmic acid is a new bisabolane-type sesquiterpene.
T31788	Fezelol	Feselol,Moschatol
	Fezelol is a sesquiterpene coumarin isolated from the fruits of Ferula badrakema.
T32256	Janerin
	Janerin is a sesquiterpene lactone.
T26546	Acantholide	NSC 277282,NSC-277282,NSC277282
	Acantholide is a Sesquiterpene lactone isolated from Acanthospermum glabratum.
T32646	Leptocarpin
	Leptocarpin is a sesquiterpene lactone extracted from Leptocarpha rivularis.
T32766	Linifolin A	NSC 153859,NSC-153859,NSC153859,PF 57,PF-57
	Linifolin A is a sesquiterpene lactone extracted from Helenium aromaticum.
T32661	Leucanthanolide
	Leucanthanolide is a sesquiterpene lactone from Montanoa leucantha.
T34932	Trichodermol	Roridin C
	Trichodermol is a fungal sesquiterpene derived from the farnesyl diphosphate pathway.
T33860	Pacifenol
	Pacifenol is a sesquiterpene isolated from sea weeds and marine alga Laurencia claviformis.
T34288	Repin
	Repin, a plant responsible for Parkinson-like disease in horses, is the principal sesquiterpene lactone extracted from Russian knapweed.
T31575	Drimane
	Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activity.
T33166	Majucin
	Majucin is a sesquiterpene derived from Illicium sp. that possess complex caged chemical architecture and remarkable neurotrophic activities with potential activity against neurodegenerative diseases.
T70240	Caparratriene
	Caparratriene is a new sesquiterpene hydrocarbon isolated from Ocotea caparrapi with potential for significant growth inhibitory activityagainst CEM leukemia cells
T36817	Quadrone
	Quadrone is a sesquiterpene originally isolated from A. terreus. It is cytotoxic to human carcinoma KB cells in vitro (EC50 = 1.3 μg/ml).
T69173	Ambrosin
	Ambrosin is a sesquiterpene lactone and a potent NF-κβ inhibitor. It is currently being studied as a potential lead drug for Alzheimer disease therapeutics.
T36906	Nanangenine G
	Nanangenine G is a drimane sesquiterpene that has been found inAspergillus.1It is cytotoxic to NS-1 mouse myeloma cells (IC50= 47 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquit...
T36904	Nanangenine B
	Nanangenine B is a drimane sesquiterpene that has been found inAspergillus.1It is active againstB. subtilis(IC50= 62 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50= 38 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Cr...
T36905	Nanangenine F
	Nanangenine F is a drimane sesquiterpene fungal metabolite that has been found inA. nanangensis.1It is active againstB. subtilis(IC50= 78 μg/ml) and cytotoxic to NS-1, DU145, and MCF-7 cancer and NFF non-cancerous cells ...
T71925	Isonanangenine B
	Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B ...
T34180	Psilostachyin C	NSC 106392
	Psilostachyin c is a member of the class of compounds known as ambrosanolides and secoambrosanolides. Ambrosanolides and secoambrosanolides are sesquiterpene lactones from the Ambrosia family, with a backbone derivative ...
T36330	Terrecyclic Acid
	Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Ter...

Compounds

Synonym: (+)-Trichodesmic acid

Target:

Fezelol

T31788

Synonym: Feselol,Moschatol

Synonym: NSC 277282,NSC-277282,NSC277282

Synonym: NSC 153859,NSC-153859,NSC153859,PF 57,PF-57

カタログ番号	製品名	別名	ターゲット
T5709	Cyperotundone		Others
	Cyperotundone is a natural product from Cyperus rotundus		Others
T9144	Telekin		Others
	Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells		Others
T8249	Hexahydrofarnesyl acetone	Phytone	Others , Antibacterial
	Hexahydrofarnesyl acetone (Phytone) enhanced both the sticky materials production and cell growth, plays some role in the increase of sticky materials and cell growth.		Others , Antibacterial
T23172	Polygodial	Tadeonal	Antifungal
	Polygodial (Tadeonal) is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.		Antifungal
T8898	Granilin	Graniline	Others , Antibacterial , Antifungal
	Granilin (Graniline)e is a natural product.		Others , Antibacterial , Antifungal
T11685	Isolongifolene	(-)-Isolongifolene	Apoptosis , Others
	Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative ...		Apoptosis , Others
T8292	(-)-Cedrene	Alpha-Cedrene	Others , Antibacterial
	(-)-Cedrene (Alpha-Cedrene) is a sesquiterpene from cedar oil that has anti-leukemia, antibacterial and anti-obesity properties.		Others , Antibacterial
T5712	Zerumbone		Antioxidant , HSV
	Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a...		Antioxidant , HSV
T2808	Bilobalide	(-)-Bilobalide	Apoptosis , Endogenous Metabolite , Autophagy
	Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.		Apoptosis , Endogenous Metabolite , Autophagy
T8516	Levomenol	(-)-α-BISABOLOL	Others
	Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.		Others
TQ0096	Scabertopin		Others
	Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities.		Others
TQ0234	Epoxymicheliolide	1β,10β-Epoxymicheliolide	Others
	Epoxymicheliolide (1β,10β-Epoxymicheliolide) is a novel guaiane-type sesquiterpene lactone isolated from Inula helenium L.		Others
T22857	Illudin S		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
	Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
T5688	Micheliolide		NOS , NF-κB , COX
	Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.		NOS , NF-κB , COX
T3865	Beta-Eudesmol	Beta-Selinenol	TRP/TRPV Channel , AChR
	beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a variety of plants, including Cannabis, and has diverse biologica...		TRP/TRPV Channel , AChR
TN7254	(E,E)-Farnesol	(2E,6E)-Farnesol	Others
	(E,E)-Farnesol ((2E,6E)-Farnesol) is a sesquiterpene acyclic alcohol produced by bacteria, protozoa, fungi, plants, and animals. (E,E)-Farnesol promotes vasodilation.		Others
T5793	Britannin		Apoptosis , AMPK , Autophagy
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.		Apoptosis , AMPK , Autophagy
T2896	Alantolactone	helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor	Apoptosis , STAT , TGF-beta/Smad
	Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...		Apoptosis , STAT , TGF-beta/Smad
T2904	Sclareolide	Norambreinolide	Others , Antibacterial
	Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antif...		Others , Antibacterial
TN1159	(1(10)E,2R,4R)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one	[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one	Others
	(1(10)E,2R,4R)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one ([(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one) is a sesquiterpene from turmeric.		Others
T2916	Patchouli alcohol	Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol	Antibacterial , Antifungal
	Patchouli alcohol (Patchoulol) is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions. Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in v...		Antibacterial , Antifungal
T13686	Ergolide		NF-κB
	Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating...		NF-κB
T6S1049	Wilforine		ATPase
	Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...		ATPase
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
T36528	Illudin M		Apoptosis , DNA Alkylator/Crosslinker
	Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It has a cytotoxicity of 6-100 nM against HL-60 human leukemia cells.Illudin M has anticancer activity and is a pre-drug for the synt...		Apoptosis , DNA Alkylator/Crosslinker
TN6835	(E)-β-Farnesene	(6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene	Antifungal
	(E)-β-Farnesene (trans-β-Farnesene) is a sesquiterpene hydrocarbon present in Phlomis aurea Decne and is the main component of many aphid alarm pheromones that interrupt aphid feeding. (E)-β-Farnesene impairs development...		Antifungal
T36473	Trans-Nerolidol
	trans-Nerolidol is a sesquiterpene that has been found in various plants, includingC. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties.1,2,3,4In...
T9279	Nerolidol acetate		Others
	Nerolidol acetate is a natural sesquiterpene with anti-cancer, anti-inflammatory, antibacterial and anti-insect activities. Nerolidol acetate can inhibit parasite activity and inhibit schistosomiasis, nematodes, malaria,...		Others
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T4672	Brevilin A		Apoptosis , Anti-infection , JAK , STAT , Autophagy
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...		Apoptosis , Anti-infection , JAK , STAT , Autophagy
T32860	Longiborneol
	Longiborneol is a sesquiterpene alcohol.
T32622	Ledol	(+)-Ledol
	Ledol is a sesquiterpene alcohol from Renealmia chrysotrycha.
T34504	Samarcandin
	Samarcandin is a natural sesquiterpene-coumarin that is isolated from F. assa-foetida.
T40204	Wilfordinine D
	Wilfordinine D is a natural sesquiterpene alkaloid.
T34513	Santalene
	Santalene is a fragrance sesquiterpene that is responsible for the fragrance of sandalwood oil.
T40582	α-Farnesene
	α-Farnesene, a sesquiterpene, is a herbivore-induced plant volatile (HIPV) that plays a significant role in insect resistance across various plant species.
TN3780	Deacetyleupaserrin		Others
	Deacetyleupaserrin is an antileukemic sesquiterpene lactone.		Others
T83160	Agarsenone
	Agarsenone, a juniperine sesquiterpene, is derived from the resin of Commiphora erythraea.
T40578	β-Bisabolene
	β-Bisabolene, a sesquiterpene extracted from Opoponax (Commiphora guidotti), serves as an anticancer agent with potential applications in breast cancer research.
T81166	Shizukaol G
	Shizukaol G, a dimeric sesquiterpene, can be isolated from the roots of Chloranthus japonicus [1].
T82969	Aristolan-1(10)-en-9-ol
	Aristolan-1(10)-en-9-ol, a sesquiterpene, is derivable from the Laurencia similis species [1].
T75543	Angulatin G
	Angulatin G (Celangulatin E), an insecticidal sesquiterpene polyol ester featuring a β-dihydroagarofuran sesquiterpene skeleton, is derived from the root bark of Celastrus angulatus. It demonstrates an LD50 of 1656.4 μg/...
T11274	Ferulenol		Others
			Others
T80845	Wallichoside
	Wallichoside, a sesquiterpene isolated from Pteris wallichiana [1], is a chemical compound with specified properties.
T82002	Juniper camphor
	Juniper camphor, a sesquiterpene compound, is isolated from the high-boiling fraction of camphor blue oil [1].
T81884	Madolin U
	Madolin U, a germacrane sesquiterpene, has been isolated from the herb Viola yedoensis [1].
T80688	β-Patchoulene
	β-Patchoulene, a tricyclic sesquiterpene extracted from Pogostemon cablin (patchouli oil), has potential therapeutic applications in the treatment of inflammatory diseases [1].
T81981	Kissoone A
	Kissoone A (compound 1), a sesquiterpene featuring a three-membered ring structure, has been isolated from valerian root [1].
T3S0541	Curzerene		Apoptosis , GST
	Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutat...		Apoptosis , GST
T78469	α-Copaene
	Alpha-Copaene (α-Copaene), a sesquiterpene hydrocarbon and volatile compound found in fruit, acts as an oviposition promoter for Bactrocera oleae [1].
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