vasorelaxant | TargetMol

カタログ番号	製品名	別名	ターゲット
T9133	Caroverine hydrochloride	Caroverine HCL	GluR , NMDAR , iGluR
	Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, an...		GluR , NMDAR , iGluR
T13341	Win 58237		Others
			Others
T72001	CB096
	CB096 is a novel inhibitor of RAN translation. specifically binds to a repeating 1 × 1 GG internal loop structure, 5'CGG/3'GGC, that is formed when r(G4C2)exp folds, also acting as a potent vasorelaxant agent, showing an...
T76386	ANP (1-30), frog
	ANP (1-30), frog, a peptide fragment sourced from atrial natriuretic peptide of frog origin, exhibits natriuretic, diuretic, and vasorelaxant properties.
T74579	Ferulic acid 4-O-sulfate
	Ferulic Acid 4-O-Sulfate (Ferulic Acid 4-Sulfate), a metabolite of Ferulic Acid, demonstrates vasorelaxant properties and reduces blood pressure in mice [1].
T72804	Isograndifoliol
	Isograndifoliol is a chemical compound that acts as a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 0.9 μM and exhibits moderate inhibition of acetylcholinesterase (AChE) with an IC50 value of...

Compounds

Caroverine hydrochloride

T9133

Synonym: Caroverine HCL

Target: GluR, NMDAR, iGluR

Ferulic acid 4-O-sulfate

カタログ番号	製品名	別名	ターゲット
TMS2171	(±)-Naringenin	Salipurpol,Naringenine,Naringenin	Potassium Channel
	(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.		Potassium Channel
TN2290	Uvaol		Endogenous Metabolite , JNK , PPAR
			Endogenous Metabolite , JNK , PPAR
TN1121	Evocarpine		Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial
	Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
TN1416	Ayanin		IL Receptor , P450 , PARP , PDE
	Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...		IL Receptor , P450 , PARP , PDE
TN1624	Ethyl cinnamate		Calcium Channel , ROS , NO Synthase
	Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl...		Calcium Channel , ROS , NO Synthase
T4001	Euxanthone	1,7-Dihydroxyxanthone	Autophagy
	Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stres...		Autophagy
TN1724	Harmalol hydrochloride	Harmidol hydrochloride	P450 , Antioxidant
	Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits ...		P450 , Antioxidant
TN6519	Saucerneol
	Saucerneol has significant cardiovascular effects such as vasorelaxant and negative inotropic actions.
T83596	(+)-Osbeckic acid
	(+)-Osbeckic acid, extracted from Tartary Buckwheat, acts as a vasorelaxant and demonstrates a significant vasorelaxant effect in Sprague-Dawley rat thoracic aorta rings, with an EC50 value of 887 μM [1].
T80867	Villocarine A
	Villocarine A, an indole alkaloid with natural vasorelaxant properties [1], is a chemical compound known for its ability to relax blood vessels.
TN1503	Cistanoside F		NADPH-oxidase
	Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide ani...		NADPH-oxidase
TN2918	3-Acetoxy-8(17),13E-labdadien-15-oic acid		cAMP , Potassium Channel , Calcium Channel
	ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane involve the activation of the endothelial NO-cGMP pathway, the ...		cAMP , Potassium Channel , Calcium Channel
T27436	GS 389	GS-389,GS389
	GS 389 is a novel tetrahydroisoquinoline analog with vasorelaxant properties. GS-389 significantly inhibited cGMP phosphodiesterase from the rabbit brain and increased cGMP levels in the rat aorta.
TN5147	Tilifodiolide		IL Receptor , TNF , GABA Receptor
	Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effe...		IL Receptor , TNF , GABA Receptor
T74193	(R)-IDHP
	(R)-IDHP, an isomer of IDHP and a metabolite of salvia, exhibits vasorelaxant properties by inhibiting calcium (Ca 2+) release and inward flow through both voltage-dependent and receptor-operated calcium channels in vasc...
TN5463	Leachianone G
	Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, it also shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. Le...