|
T21944L |
BIM 23056 Acetate
|
BIM 23056 Acetate (150155-61-6 Free base) |
Others
|
|
BIM 23056 Acetate is a potent and surmountable human recombinant sst5 receptor antagonist. |
|
T21661L |
BIM 23042 Acetate
|
BIM 23042 Acetate (111857-96-6 Free base) |
Others
|
|
BIM 23042 Acetate [D-Nal-Cys-Tyr- D-Trp-Lys-Val-Cys-Nal-NH2] is a selective antagonist of neuromedin B. |
|
T39262L |
BIM-23190 aceate
|
|
Somatostatin
|
|
BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies. |
|
T16519L |
BIM-46187 4HCl
|
PH-064 4HCl |
Others
|
|
BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor. |
|
T34281 |
Relamorelin
|
BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 |
GHSR
|
|
Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ... |
|
T26817 |
Bim-BLK-A
|
Bim Blocker A,Compound A,Bim BLK A,BimBLKA |
|
|
Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of t... |
|
T25154 |
Bim 21009
|
LHRH-Ncpapa,Bim-21009,Bim21009,LHRHNcpapa,LHRH Ncpapa |
|
|
Bim 21009 is an inhibitor of gonadorelin. |
|
T39262 |
BIM-23190
|
|
|
|
BIM-23190 is a somatostatin analog that acts as a selective agonist for SSTR2 and SSTR5 receptors. It displays potency with K i values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 finds utility in ... |
|
T69993 |
BIM-46068
|
|
|
|
BIM-46068 is a potent and specific inhibitor of human farnesyltransferase. In regard to a panel of cell lines, using the Compare analysis to determine the Pearson coefficient correlation, the anti-proliferative spectrum ... |
|
T8359 |
Lanreotide acetate
|
Lanreotide acetate (108736-35-2 free base),BIM 23014 (acetate),BIM 23014 acetate |
Others
|
|
Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome |
|
T70039 |
BIM-46174
|
|
|
|
BIM-46174 is a New Inhibitor of the Heterotrimeric Gα/Gβγ Protein Complex. BIM-46174 acts as a selective inhibitor of heterotrimeric G-protein complex. BIM-46174 prevents the heterotrimeric G-protein signaling linked to... |
|
T37109 |
BIM-23190 hydrochloride
|
|
|
|
BIM-23190 hydrochloride, a selective agonist for somatostatin receptors SSTR2 and SSTR5 with Ki values of 0.34 nM and 11.1 nM respectively, is a somatostatin analog utilized in research on cancer and acromegaly[1][3]. |
|
TP2224 |
BIM, Biotinylated
|
|
Others
|
|
BIM, Biotinylated is a Bim peptide fragment (residues 81-106) with a biotin moiety attached. |
|
T10550 |
Bisindolylmaleimide X hydrochloride
|
BIM-X hydrochloride,Ro31-8425 hydrochloride |
CDK
,
PKC
|
|
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM). |
|
TP1718 |
Bim BH3, Peptide IV TFA (721885-31-0 free base)
|
Bim BH3, Peptide IV TFA |
|
|
Bim BH3, Peptide IV TFA is a 26-site residue of BH3 protein Bim, belonging to the pro-apoptotic group of bcl-2 protein family. |
|
TP1611 |
Bim BH3, Peptide IV
|
|
|
|
This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins. |
|
T12882L |
Setmelanotide Acetate(920014-72-8 free base)
|
RM-493 Acetate,IRC-022493 Acetate,BIM-22493 Acetate |
Melanocortin Receptor
|
|
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively). |
|
TP1215 |
Abaloparatide TFA
|
BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA |
Others
|
|
Abaloparatide TFA (BIM 44058 TFA) is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis like the related drug teriparatide. |
|
T21410 |
Triptorelin acetate(57773-63-4 free base)
|
Wy 42422,Triptorelin Acetate,CL 118532,AY 25650,CL 118,532,Wy 42462,BIM 21003 |
GNRH Receptor
|
|
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stim... |
|
T82883 |
BIM-23027
|
|
|
|
BIM-23027 is a selective sst 2 receptor agonist (EC 50 = 0.32 nM) with effects analogous to the cyclic tetradecapeptide somatostatin (SRIF). It promotes dopamine release through a Glu-dependent mechanism [1] [2]. |
|
T75707 |
BIM-26226
|
|
|
|
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is ut... |
|
T80038 |
Bim BH3
|
|
|
|
Bim BH3 is a bioactive peptide that belongs to the pro-apoptotic Bcl-2 family of proteins. |
|
T69994 |
BIM-46050
|
|
|
|
BIM-46050 is a potent and specific inhibitor of human farnesyltransferase. BIM-46050 is free acidic form of BIM-46068. The IC50 values for in vitro inhibition of human brain FTase indicate that BIM-46050 and the ester fo... |
|
T75844 |
BIM-23056 TFA
|
|
|
|
BIM 23056 TFA, a potent linear octapeptide antagonist of sst3 and sst5 somatostatin receptors, exhibits inhibition constants (K_i) of 10.8 for sst3 and 5.7 for sst5, according to reference [1]. |
|
T62157 |
Bim-IN-1
|
|
|
|
Bim-IN-1 is a potent inhibitor of Bim expression with low toxicity, Bim-IN-1 reduces Bim expression levels with little inhibition of protein kinase A. |
|
T16519 |
PH-064
|
BIM-46187 |
Others
|
|
PH-064 (BIM-46187) is a heterotrimeric G-protein complex inhibitor. |
|
T83114 |
Angiopep-Bim BH3 hydrochloride
|
|
|
|
Angiopep-Bim BH3 hydrochloride, a peptode that penetrates the blood-brain barrier (BBB), may serve as a tool to study the permeability of central nervous system (CNS) therapeutics [1]. |
|
T76030 |
Bim BH3, Peptide IV TFA
|
|
|
|
Bim BH3, Peptide IV TFA, is a 26-residue peptide derived from the BH3-only protein Bim, a member of the pro-apoptotic Bcl-2 protein family [1] [2]. |
|
T40886 |
Onzigolide
|
BIM-23A760,TBR-760,Onzigolide |
|
|
Onzigolide (BIM-23A760), a chimeric compound combining properties of both dopamine and somatostatin, exhibits strong agonistic activity towards the D2 subtype of dopamine receptors (D2R) as well as type 2 somatostatin re... |
|
T70038 |
MJN68390
|
|
Caspase
|
|
MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10. |
|
T81949 |
Lanreotide diTFA
|
BIM 23014 diTFA |
|
|
Lanreotide (BIM 23014) diTFA, a somatostatin analogue, exhibits antineoplastic activity and may be utilized in carcinoid syndrome research [1] [2]. |
|
T12882 |
Setmelanotide
|
BIM-22493,IRC-022493,RM-493 |
Melanocortin Receptor
|
|
Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively). |
|
T20534 |
Lanreotide
|
BIM 23014,Somatulin,Lanreotide Autogel,Somatuline,Ipstyl |
|
|
Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours. |
|
T39236 |
Relamorelin acetate
|
Relamorelin acetate,RM-131 acetate,BIM-28131acetate |
|
|
Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki v... |
|
T25087 |
Angiopeptin
|
D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2,Bim 23014 C |
|
|
Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries. |
|
T69992 |
Glutathione sodium
|
|
|
|
Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. |
|
T7790 |
Bisindolylmaleimide V
|
|
PKC
,
S6 Kinase
|
|
Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor. |
|
T5104 |
BTSA1
|
|
Apoptosis
,
BCL
|
|
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. |
|
T2099 |
ABT-737
|
|
Mitophagy
,
BCL
,
Autophagy
|
|
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM). |
|
T13091 |
Taspoglutide
|
R1583,BIM51077,ITM077 |
Others
|
|
|
|
T3485 |
Probimane
|
AT-2153,MM-159 |
Others
|
|
Probimane (AT-2153) had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16. |
|
T8649 |
TMBIM6 antagonist-1
|
BAX-inhibitor-1,BIA |
mTOR
|
|
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor |
|
T0952 |
Carbimazole
|
Athyromazole,Carbimazol,Neomercazole |
Thyroid hormone receptor(THR)
|
|
Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease. |
|
T2265 |
Bimiralisib
|
5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2 |
Others
,
PI3K
,
S6 Kinase
,
mTOR
|
|
Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to ... |
|
T19028 |
Monochlorobimane
|
mBBr,Chlorobimane |
|
|
Monochlorobimane (mBBr) is a fluorescent dye with a λex value of 380 nm and a λem value of 470 nm.Monochlorobimane can be used to measure glutathione (GSH) in cells. |
|
T18929 |
Bromobimane
|
Monobromobimane |
Autophagy
|
|
Bromobimane (Monobromobimane) is a non-fluorescent substance, but reacts with thiols to produce a fluorescent product.Bromobimane is used as a probe, often in clinical medicine, to test for sulfide levels in blood. |
|
T3481 |
Bimolane
|
|
Topoisomerase
|
|
Bimolane is a topoisomerase II inhibitor. |
|
T21946 |
BIMU 8
|
|
5-HT Receptor
|
|
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4. |
|
T2538 |
Bimatoprost
|
AGN 192024 |
Prostaglandin Receptor
|
|
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension. |
|
T3623 |
Cobimetinib
|
RG7420,XL518,GDC-0973 |
Apoptosis
,
MEK
|
|
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e... |
