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Search Results for " DOR "

ターゲット

80

阻害剤

20

天然化合物

9

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
TP2036L DPDPE TFA (88373-73-3 free base) DPDPE TFA Opioid Receptor
DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
T2134 Dorzolamide hydrochloride MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl Carbonic Anhydrase
Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water ...
T7830 Windorphen Wnt/beta-catenin
Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.
T62839 Dalzanemdor SAGE-718 NMDAR , iGluR
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction.
T72166 Xanthine oxidoreductase-IN-5 Xanthine Oxidase
Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50 : 55 nM).Xanthine oxidoreductase-IN-5 may be used in studies of acute hyperuricemia.
T67888L Samidorphan HCl Samidorphan HCl(852626-89-2 free base) Opioid Receptor
Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors. Samidorphan HCl is a novel μ-opioid receptor antagonist, a partial agonis...
T1037 Doripenem monohydrate S 4661 monohydrate,Doripenem Hydrate,S-4661 Antibacterial , Antibiotic
Doripenem monohydrate (S 4661 monohydrate) is a broad-spectrum injectable antibiotic, used for Gram-positive, Gram-negative and anaerobic pathogens.
T3632 Doravirine MK-1439 HIV Protease , Reverse Transcriptase
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
T30098 Aplindore Fumarate Aplindore,DAB-452 Fumarate,DAB-452 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H...
T6277 Doramapimod BIRB 796 Raf , p38 MAPK , Autophagy
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
T21511L Alpha-Endorphin acetate alpha-Endorphin acetate (59004-96-5 Free base) Others
alpha-Endorphin acetate is related peptides of the pro-opiomelanocortin family with characteristic biological activities, were purified to homogeneity from single human pituitary.
TP2322L Beta-Neoendorphin acetate(77739-21-0 free base) Opioid Receptor
beta-Neoendorphin acetate is an agonist of κ-opioid receptor
TP1508L N-Acetyl-α-Endorphin acetate(88264-63-5 free base) Others
N-Acetyl-α-Endorphin acetate is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.
T72165 Xanthine oxidoreductase-IN-3 Xanthine Oxidase
Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50: 26.3 nM).Xanthine oxidoreductase-IN-3 can be used in acute hyperuricemia studies.
T67782 Daridorexant hydrochloride Nemorexant hydrochloride,Quviviq OX Receptor
Daridorexant hydrochloride (Nemorexant hydrochloride) is a New Dual Orexin Receptor Antagonist. Daridorexant hydrochloride can be used for Insomnia research.
T22314 Doripenem Antibacterial , Antibiotic
Doripenem is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.
T70047 Bedoradrine Bedoradrine free base Adrenergic Receptor
Bedoradrine free base is a novel, highly selective β2-adrenoceptor agonist for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
T72078 Xanthine oxidoreductase-IN-4 Xanthine Oxidase
Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor that inhibits XOR with an IC50 value of 29.3 nM.Xanthine oxidoreductase-IN-4 can be used to study hyperuricemia.
T38193L β-Endorphin (1-27) (human) acetate β-Endorphin (1-27) (human) acetate(76622-84-9 Free base) Opioid Receptor
β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity. β-Endorphin (1-27) (human) acetate is an agonist of opioid receptor, showing preferred affinity ...
T69146 Suksdorfin PPAR
Suksdorfin has hypoglycemic effects, promotes adipocyte differentiation and enhances lipocalin production, activates peroxisome proliferator-activated receptor gamma (PPARγ), promotes insulin-dependent glucose uptake by ...
T15159 Dorzagliatin HMS5552 Glucokinase
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
T15756 Lidorestat IDD-676 Reductase
Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces the formation of cataracts. Lidorestat can be used to treat...
T5015 Gonadorelin Acetate (33515-09-2 free base) Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate Reductase
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T5500 DORA-22 OX Receptor
DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory
T26760 Bedoradrine sulfate KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246 Adrenergic Receptor
Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease.
T1977 Dorsomorphin Compound C,BML-275 AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...
T5015L2 Gonadorelin HCl Factrel,AY-24,031,AY24,031,AY 24,031,LH-RH hydrochloride,Gonadorelin hydrochloride
Gonadorelin HCl, as a decapeptide, can stimulate the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE, and FOLLICLE STIMULATING HORMONE.
T22527 6'-Iodoresiniferatoxin Others
TRPV1 (VR1) vanilloid receptor partial agonist
T14153 Aladorian ARM036 Others
Aladorian (ARM036) is a benzothiazepine derivative and it has anti-arrhythmia effect. Aladorian is used for the research of heart failure and catecholaminergic polymorphic ventricular tachycardia[1][2].
T75592 Odonthobuthus Doriae Venom
Odonthobuthus Doriae Venom, extracted from the scorpion Odonthobuthus Doriae, exhibits neurotoxicity through the modulation of ion channels.
T76285 β-Endorphin (6-31), human β-EP (6-31), human Opioid Receptor
β-Endorphin is an endogenous opioid neuropeptide and opioid receptor agonist that preferentially binds to μ-opioid receptors. Produced by specific neurons within the central and peripheral nervous system, it is one of th...
T126476 Moellendorffilin
Moellendorffilin is a useful organic compound for research related to life sciences and the catalog number is T126476.
T68929 Lidorestat monohydrate
Lidorestat monohydrate is an aldose reductase inhibitor potentially for the treatment of diabetic neuropathy and diabetic complications.
T124568 Doronine
Doronine is a useful organic compound for research related to life sciences and the catalog number is T124568.
T22515 5'-Iodoresiniferatoxin Others
TRPV1 (VR1) receptor antagonist
T22743 Dorzolamide Others
Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
T61165 Indoramin
Indoramin, an orally active antihypertensive agent, exhibits selectivity for the α 1A -adrenoceptor [1].
T123854 Daphnodorin B
Daphnodorin B is a useful organic compound for research related to life sciences and the catalog number is T123854.
T70964 Olanzapine/Samidorphan
Olanzapine/Samidorphan is a combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment...
T67888 Iso-Samidorphan (9ξ,13ξ,14ξ)-17-(Cyclopropylmethyl)-4,14-dihydroxy-6-oxomorphinan-3-carboxamide Others
Iso-Samidorphan is a biochemical reagent that can be used in biological experiments.
T31566 Doranidazole PR-350,PR350,PR-000350,RP-343,PR000350
Dornidazole (PR-000350, PR-350, RP-343, PR-69) is an effective radiosensitizer for hypoxic cells with the potential for the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer.
T124290 Doronenine
Doronenine is a useful organic compound for research related to life sciences and the catalog number is T124290.
T35733 Doramectin aglycone
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysi...
T82532 Dorlimomab aritox 4197X-RA,MDX-RA (ricin A chain) immunotoxin
Dorlimomab aritox (4197X-RA; MDX-RA [ricin A chain] immunotoxin) is a monoclonal antibody of mouse origin that is conjugated to the A chain of ricin [1].
T29818 Aladorian sodium
Aladorian sodium is used for Treatment of Cardiovascular Diseases.
T70072 Aplindore
Aplindore is a dopamine receptor agonist used in the therapeutic treatment of Parkinson's Disease.
T76913 Avdoralimab
Avdoralimab (IPH 5401), a fully human IgGκ monoclonal antibody, specifically inhibits the complement C5a receptor 1 (C5aR1) by preventing its interaction with C5a. This compound is utilized in research concerning complem...
TP1514 α-Neoendorphin (1-8) α-Neoendorphin 1-8
α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin. α-Neoendorphin is an endogenous opioid peptide and is a part for the neoendorphins which are a group of endogenous opioid pept...
T80515 β-Endorphin (1-27) (human) Opioid Receptor
β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17, and 39.82 nM, respectively. It inhibits analgesia induced by b...

Compounds

DPDPE TFA (88373-73-3 free base)
TP2036L
Synonym: DPDPE TFA
Target: Opioid Receptor
Dorzolamide hydrochloride
T2134
Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl
Target: Carbonic Anhydrase
Windorphen
T7830
Synonym:
Target: Wnt/beta-catenin
Dalzanemdor
T62839
Synonym: SAGE-718
Target: NMDAR, iGluR
Xanthine oxidoreductase-IN-5
T72166
Synonym:
Target: Xanthine Oxidase
Samidorphan HCl
T67888L
Synonym: Samidorphan HCl(852626-89-2 free base)
Target: Opioid Receptor
Doripenem monohydrate
T1037
Synonym: S 4661 monohydrate,Doripenem Hydrate,S-4661
Target: Antibacterial, Antibiotic
Doravirine
T3632
Synonym: MK-1439
Target: HIV Protease, Reverse Transcriptase
Aplindore Fumarate
T30098
Synonym: Aplindore,DAB-452 Fumarate,DAB-452
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Doramapimod
T6277
Synonym: BIRB 796
Target: Raf, p38 MAPK, Autophagy
alpha-Endorphin acetate
T21511L
Synonym: alpha-Endorphin acetate (59004-96-5 Free base)
Target: Others
beta-Neoendorphin acetate(77739-21-0 free base)
TP2322L
Synonym:
Target: Opioid Receptor
N-Acetyl-α-Endorphin acetate(88264-63-5 free base)
TP1508L
Synonym:
Target: Others
Xanthine oxidoreductase-IN-3
T72165
Synonym:
Target: Xanthine Oxidase
Daridorexant hydrochloride
T67782
Synonym: Nemorexant hydrochloride,Quviviq
Target: OX Receptor
Doripenem
T22314
Synonym:
Target: Antibacterial, Antibiotic
Bedoradrine
T70047
Synonym: Bedoradrine free base
Target: Adrenergic Receptor
Xanthine oxidoreductase-IN-4
T72078
Synonym:
Target: Xanthine Oxidase
β-Endorphin (1-27) (human) acetate
T38193L
Synonym: β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)
Target: Opioid Receptor
Suksdorfin
T69146
Synonym:
Target: PPAR
Dorzagliatin
T15159
Synonym: HMS5552
Target: Glucokinase
Lidorestat
T15756
Synonym: IDD-676
Target: Reductase
Gonadorelin Acetate (33515-09-2 free base)
T5015
Synonym: Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate
Target: Reductase
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
DORA-22
T5500
Synonym:
Target: OX Receptor
Bedoradrine sulfate
T26760
Synonym: KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246
Target: Adrenergic Receptor
Dorsomorphin
T1977
Synonym: Compound C,BML-275
Target: AMPK, Autophagy, TGF-beta/Smad
Gonadorelin HCl
T5015L2
Synonym: Factrel,AY-24,031,AY24,031,AY 24,031,LH-RH hydrochloride,Gonadorelin hydrochloride
Target:
6'-Iodoresiniferatoxin
T22527
Synonym:
Target: Others
Aladorian
T14153
Synonym: ARM036
Target: Others
Odonthobuthus Doriae Venom
T75592
Synonym:
Target:
β-Endorphin (6-31), human
T76285
Synonym: β-EP (6-31), human
Target: Opioid Receptor
Moellendorffilin
T126476
Synonym:
Target:
Lidorestat monohydrate
T68929
Synonym:
Target:
Doronine
T124568
Synonym:
Target:
5'-Iodoresiniferatoxin
T22515
Synonym:
Target: Others
Dorzolamide
T22743
Synonym:
Target: Others
Indoramin
T61165
Synonym:
Target:
Daphnodorin B
T123854
Synonym:
Target:
Olanzapine/Samidorphan
T70964
Synonym:
Target:
Iso-Samidorphan
T67888
Synonym: (9ξ,13ξ,14ξ)-17-(Cyclopropylmethyl)-4,14-dihydroxy-6-oxomorphinan-3-carboxamide
Target: Others
Doranidazole
T31566
Synonym: PR-350,PR350,PR-000350,RP-343,PR000350
Target:
Doronenine
T124290
Synonym:
Target:
Doramectin aglycone
T35733
Synonym:
Target:
Dorlimomab aritox
T82532
Synonym: 4197X-RA,MDX-RA (ricin A chain) immunotoxin
Target:
Aladorian sodium
T29818
Synonym:
Target:
Aplindore
T70072
Synonym:
Target:
Avdoralimab
T76913
Synonym:
Target:
α-Neoendorphin (1-8)
TP1514
Synonym: α-Neoendorphin 1-8
Target:
β-Endorphin (1-27) (human)
T80515
Synonym:
Target: Opioid Receptor
1 2
カタログ番号 製品名 別名 ターゲット
T0969 Doramectin Dectomax,Cyclohexylavermectin B1 Others , Antibiotic , Parasite
Doramectin (Dectomax) is an antiparasitic agent.
TN5234 Vindorosine Calcium Channel , Sodium Channel
Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.
TN2005 Odoratisol A Others
Odoratisol A is a natural product from Myristica fragrans Houtt.
TN4694 Odoratone Others
Odoratone shows insecticidal activities, it shows mortality on fourth instar larvae of mosquitoes (Anopheles stephensi) with LC(50) values of 154 ppm. Odoratone exhibits strong antifeedant activity against Pieris brassic...
TN4696 Odorinol Antifection
Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease virus (RVD) in chick embryo.
TN3159 6-Deoxy-9alpha-hydroxycedrodorin Others
6-Deoxy-9alpha-hydroxycedrodorin shows potential value in the selection of insect-resistant clones for timber plantations.
TN3888 Dorsmanin A Others
Dorsmanin A is a natural product from Psoralea corylifolia.
TN3835 Desacetyldoronine Others
Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.
TN3284 8-Hydroxyodoroside A Others
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine an...
TN4285 Isodorsmanin A Others
Isodorsmanin A is a natural product for research related to life sciences. The catalog number is TN4285 and the CAS number is 118266-99-2.
T75669 Odoroside A
Odoroside A, extracted from the leaves of Nerium oleander Linn., exhibits anti-cancer properties by inducing apoptosis and cell cycle arrest via the ROS/p53 signaling pathway, resulting in tumor cell death [1].
T76027 β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3] [4].
T81621 Odoratisol B
Odoratisol B, a natural product, is isolated from Machilus odoratissima NEES [1].
TN6351 Dorsmanin I
Dorsmanin I is a natural product for research related to life sciences. The catalog number is TN6351 and the CAS number is 329703-46-0.
TN4695 Odorine Others
Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. It was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing t...
TN4697 Odoroside H ATPase , Potassium Channel , Sodium Channel
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN2006 Odoriflavene Others
Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in...
T13433 β-Endorphin, human Others
β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus,and is an agonist of opioid receptor.
TN5589 6α-Hydroxynidorellol
6alpha-Hydroxynidorellol is a natural product from Callicarpa macrophylla.
T83913 Mitraciliatine
Mitraciliatine, an alkaloid discovered in M. speciosa (Kratom in Thai), acts as a partial agonist for the μ-opioid receptor (MOR) and an agonist for the κ-opioid receptor (KOR), demonstrating selectivity for these recept...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00290 Odorant-binding Protein, Bovine, Recombinant Bovine E. coli
This protein binds a wide variety of chemical odorants. Odorant-binding Protein, Bovine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.5 kDa and the accession number is P0743...
TMPH-00211 OmpA Protein, Borrelia burgdorferi, Recombinant (His) Borrelia burgdorferi P. pastoris (Yeast)
OmpA Protein, Borrelia burgdorferi, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P0A3N6.
TMPH-03070 TAP Protein, Ornithodoros moubata, Recombinant (His) Ornithodoros moubata P. pastoris (Yeast)
TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
TMPH-03071 TAP Protein, Ornithodoros moubata, Recombinant (His & Myc & SUMO) Ornithodoros moubata E. coli
TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
TMPH-00212 OmpA Protein, Borrelia burgdorferi, Recombinant (His & Myc) Borrelia burgdorferi E. coli
OmpA Protein, Borrelia burgdorferi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.9 kDa and the accession number is P0A3N6.
TMPH-00210 Flagellin Protein, Borrelia burgdorferi, Recombinant (His & SUMO) Borrelia burgdorferi E. coli
Component of the core of the flagella. Flagellin Protein, Borrelia burgdorferi, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.8 kDa and the...
TMPH-00209 CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc) Borrelia burgdorferi E. coli
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-02390 Odorant receptor Protein, Larimichthys crocea, Recombinant (His) Larimichthys crocea E. coli
Odorant receptor Protein, Larimichthys crocea, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is F2XEX3.
TMPH-00291 Odorant-binding Protein, Bovine, Recombinant (His & SUMOstar) Bovine P. pastoris (Yeast)
This protein binds a wide variety of chemical odorants. Odorant-binding Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 34.5 kDa and the ac...