|
T3058 |
(Z)-SMI-4a
|
TCS PIM-1 4a,SMI-4a |
Pim
|
|
(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM. |
|
T3989 |
SMI-16a
|
PIM1/2 Kinase Inhibitor VI |
Pim
|
|
SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against... |
|
T6974 |
Saccharin 1-methylimidazole
|
SMI,Saccharin 1-methylimidazole (SMI) |
DNA/RNA Synthesis
|
|
Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis. |
|
T26195 |
SMI481
|
NPPM-6748-481,NPPM 6748-481,NPPM6748481,SMI-481 SMI 481,NPPM 6748481 |
Others
|
|
SMI481 (NPPM6748481) is the first small-molecule Sec14-like phosphatidylinositol transfer proteins (PITPs) inhibitor. |
|
T4215 |
TCS-PIM-1-4a
|
SMI-4a |
Apoptosis
,
Pim
|
|
TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM). |
|
T24808 |
SMI-6860766
|
TRAFSTOP 6860766,TRAF-STOP 6860766,SMI 6860766,TRAFSTOP6860766,SMI6860766 |
|
|
SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice. |
|
T74733 |
OSM-SMI-10B
|
|
|
|
OSM-SMI-10B, a derivative of OSM-SMI-10, effectively inhibits Oncostatin M (OSM)-induced STAT3 phosphorylation in cancer cells when co-incubated with OSM [1]. |
|
T16290 |
NIK SMI1
|
|
NF-κB
|
|
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM). |
|
T16409 |
OSMI-1
|
|
Others
,
Acyltransferase
|
|
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans. |
|
T7165 |
Basmisanil
|
RG1662,RO5186582 |
GABA Receptor
|
|
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndro... |
|
T16901 |
SMIP004
|
|
Apoptosis
,
Others
,
E1/E2/E3 Enzyme
|
|
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells. |
|
T11315 |
Fosmidomycin sodium salt
|
FR-31564 sodium salt |
Antibiotic
,
Parasite
|
|
Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria. |
|
T12328 |
OSMI-4
|
|
Others
|
|
|
|
T4370 |
Resminostat hydrochloride
|
4SC-201 hydrochloride,RAS2410 hydrochloride |
HDAC
|
|
Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM). |
|
T23372 |
SMIFH2
|
|
Others
|
|
SMIFH2 is formin homology 2 (FH2) domains inhibitor. |
|
T83646 |
(S)-OSMI 3
|
Ent-OSMI-3 |
Others
|
|
(S)-OSMI 3 (Ent-OSMI-3) has anti-inflammatory and anti-tumour activity and can be used to study diabetes and neurodegenerative diseases. |
|
T12327 |
OSMI-3
|
|
Others
|
|
|
|
T22746 |
Tesmilifene fumarate
|
DPPE fumarate |
Histamine Receptor
|
|
Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。 |
|
T125271 |
Methyl jasminoside
|
|
|
|
Methyl jasminoside is a useful organic compound for research related to life sciences. The catalog number is T125271 and the CAS number is 229467-41-8. |
|
T34933 |
Trichodesmic acid
|
(+)-Trichodesmic acid |
|
|
Trichodesmic acid is a new bisabolane-type sesquiterpene. |
|
T24582 |
P18SMI-21
|
p18SMI 21 |
|
|
p18SMI-21 is a novel INK4C inhibitor. It also specifically blocking the bioactivity of p18 protein. |
|
T6637 |
Resminostat
|
4SC-201,RAS2410 |
HDAC
|
|
|
|
T38831 |
Endoplasmic reticulum dye 1
|
|
|
|
Endoplasmic reticulum dye 1 is a highly effective live cell imaging agent used for detecting exocytotic events occurring at the plasma membrane. This compound exhibits minimal cytotoxicity and is resistant to photobleach... |
|
T78018 |
Plasminogen
|
|
|
|
Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec... |
|
T28283 |
P18SMI-22
|
p18SMI 22 |
|
|
p18SMI-22 is an INK4C inhibitor. |
|
T126193 |
Diosmin Impurity 5
|
|
|
|
Diosmin Impurity 5 is a useful organic compound for research related to life sciences and the catalog number is T126193. |
|
T32267 |
Jasminine
|
|
|
|
Jasminine is a natural naphthyridine alkaloid. |
|
T32635 |
Orismilast
|
LEO 32731,LEO-32731,LEO32731 |
|
|
LEO-32731 is a bioactive chemical. |
|
T25995 |
Prospasmine
|
Tropiston |
|
|
Prospasmine is an anticholinergic. |
|
T131529 |
Eudesmin (Humbertiol)
|
|
|
|
Eudesmin (Humbertiol) is a useful organic compound for research related to life sciences and the catalog number is T131529. |
|
T30160 |
ASMI
|
|
|
|
ASMI is a cell-permeable cysteine selective, sensitive, and ratiometric fluorescent turn-on probe. |
|
T24583 |
P18SMI-41
|
p18SMI 41 |
|
|
p18SMI-41 is a novel INK4C inhibitor. It also specifically blocking the bioactivity of p18 protein. |
|
T63988 |
(Rac)-OSMI-1
|
|
|
|
(Rac)-OSMI-1 is a racemate of OSMI-1. OSMI-1 is an inhibitor of O-GlcNAc transferase (OGT) (IC50: 2.7 μM). OSMI-1 inhibits protein O-linked N-acetylglucosaminoglycans (O-GlcNAcylation) in mammalian cell lines and does no... |
|
T36540 |
Nodusmicin
|
|
|
|
Nodusmicin is a macrolide antibiotic. It has activity against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250, and 250 μg/ml for UC-76, UC-6685, and UC-6690 strains, respectively. |
|
T29474 |
6-Hydroxymyosmine
|
|
|
|
6-Hydroxymyosmine is a Nornicotine metabolite. |
|
T125116 |
Diosmin Impurity 8
|
|
|
|
Diosmin Impurity 8 is a useful organic compound for research related to life sciences and the catalog number is T125116. |
|
T70623 |
Esmirtazapine HCl
|
|
|
|
Esmirtazapine HCl is the salt form of Esmirtazapine, a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscar... |
|
T25777 |
Marasmic acid
|
CCRIS 1701,NSC-318506,LACHNELLA FUNGUS,NSC 318506,NSC318506 |
|
|
Marasmic acid is a bioactive antifungal. |
|
T12326 |
OSMI-2
|
|
Others
|
|
OSMI-2 is a cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT). |
|
T23759 |
Aspergillomarasmine A
|
Toxin C (Pyrenophora teres) |
|
|
Aspergillomarasmine A is a polyamine acid naturally produced by the mold Aspergillus Versicolor. |
|
T125434 |
Rosmic acid
|
|
|
|
Rosmic acid is a useful organic compound for research related to life sciences. The catalog number is T125434 and the CAS number is 197799-63-6. |
|
T130814 |
Chamaejasmin
|
|
|
|
Chamaejasmin is a useful organic compound for research related to life sciences and the catalog number is T130814. |
|
T32266 |
Jasmine lactone
|
Jasmolactone, delta-,EINECS 247-074-2,FEMA No. 3745 |
|
|
Jasmine lactone is a lactone and aroma compound. Its chemical formula is C10H16O2. It exists in some natural product in jasmine oil, tuberose, gardenia, mimosa, honeysuckle, lily, tea, peach, and ginger. It can be main... |
|
T15774 |
Losmiprofen
|
|
Others
|
|
Losmiprofen is a nonsteroidal compound of antiinflammatory. |
|
T126179 |
Jasminoside N
|
|
|
|
Jasminoside N is a useful organic compound for research related to life sciences. The catalog number is T126179 and the CAS number is 1231710-13-6. |
|
T33024 |
Lycomarasmine
|
|
|
|
Lycomarasmine is a bioactive chemical. |
|
T34830 |
Tetrofosmin
|
P 53,P53 |
|
|
Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. |
|
T28773 |
SI-2
|
SI2,EPH 116,EPH116,EPH-116 |
Others
|
|
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast can... |
|
T12906 |
SI-2 hydrochloride
|
EPH 116 hydrochloride |
Src
|
|
SI-2 hydrochloride (EPH 116 hydrochloride) is a highly promising inhibitor of SRC-3 SMI: SRC-3 (PPI)(IC50 values of 3-20 nM for breast cancer cell death), with acceptable oral availability. |
