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T6713 |
Ulipristal
|
|
Estrogen/progestogen Receptor
,
Progesterone Receptor
|
|
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. |
|
T2527 |
Ulipristal acetate
|
Ulipristal,CDB-2914 |
Estrogen/progestogen Receptor
,
Progesterone Receptor
,
Autophagy
|
|
Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereb... |
|
T21404 |
Fluticasone furoate
|
Veramyst,Allermist,Avamys,Fluticasone furoate |
Glucocorticoid Receptor
|
|
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... |
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T1531 |
Mometasone furoate
|
Sch32088 |
Glucocorticoid Receptor
|
|
Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski... |
|
T6503 |
Fluorometholone Acetate
|
NSC 47438,Flarex,Eflone,Oxylone acetate |
Glucocorticoid Receptor
,
Carbonic Anhydrase
|
|
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye. |
|
T0188 |
Fluticasone (propionate)
|
CCI-187881,Fluticasone propionate |
Glucocorticoid Receptor
,
Virus Protease
,
Estrogen/progestogen Receptor
,
Phospholipase
,
Endogenous Metabolite
|
|
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. |
|
T4602 |
Hydrocortisone hemisuccinate
|
Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate |
Glucocorticoid Receptor
,
Others
,
Interleukin
|
|
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent. |
|
T15102 |
Dexamethasone palmitate
|
DXP |
Glucocorticoid Receptor
|
|
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... |
|
T0208 |
Prednisolone disodium phosphate
|
Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium |
Glucocorticoid Receptor
|
|
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties. |
|
T0977 |
Medrysone
|
Gimeracil,6α-Methyl-11β-hydroxyprogesterone |
Glucocorticoid Receptor
,
Others
|
|
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular ... |
|
T22367 |
Methylprednisolone succinate
|
Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate |
Glucocorticoid Receptor
|
|
Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent. |
|
T9047 |
Fluprednisolone
|
NSC-47439,NSC 47439,NSC47439 |
Others
|
|
Fluprednisolone (NSC-47439) is a synthetic glucocorticoid that has anti-inflammatory properties. |
|
T6502 |
Fluocinonide
|
Lidex,Metosyn,Topsyn |
Glucocorticoid Receptor
|
|
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent. |
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T21361 |
Alclometasone dipropionate
|
Vaderm,Sch 22219,Aclovate,Delonal |
Others
|
|
Alclometasone dipropionate （Sch 22219） is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the stu... |
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T8396 |
Prednisone acetate
|
Prednisone 21-acetate |
Glucocorticoid Receptor
|
|
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory. |
|
T1559 |
Betamethasone dipropionate
|
Diprolene AF,SCH 11460,Betamethasone 17,21-dipropionate,Diprolene,Diprosone |
Glucocorticoid Receptor
|
|
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to sp... |
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T15451 |
GW-870086
|
|
Glucocorticoid Receptor
|
|
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB). |
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T0337 |
Prednisolone acetate
|
Omnipred,Prednisolone-21-acetate |
Glucocorticoid Receptor
|
|
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. |
|
T1124 |
Flumethasone
|
Flumetasone,RS-2177,NSC-54702 |
Glucocorticoid Receptor
|
|
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties. |
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T2548 |
Diflorasone
|
|
Glucocorticoid Receptor
|
|
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti... |
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T14981 |
Clobetasone butyrate
|
|
Glucocorticoid Receptor
|
|
Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tis... |
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T6465 |
Dexamethasone Sodium Phosphate
|
Dexadreson,Dexagro,Dalalone |
IL Receptor
,
COX
|
|
Dexamethasone Sodium Phosphate (Dexadreson) , an interleukin receptor modulator, has anti-inflammatory and immunosuppressant effects. It belongs to a potent glucocorticoid class of steroid synthetic drugs. |
|
T1561 |
Clobetasol propionate
|
Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,CCl 4725 |
Glucocorticoid Receptor
,
P450
|
|
Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain a... |
|
T1163 |
Betamethasone valerate
|
Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq |
Glucocorticoid Receptor
|
|
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. |
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T1076 |
Dexamethasone
|
MK 125,Prednisolone F,NSC 34521,Hexadecadrol |
Glucocorticoid Receptor
,
Mitophagy
,
IL Receptor
,
SARS-CoV
,
Antibacterial
,
Antibiotic
,
Autophagy
,
Complement System
|
|
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced... |
|
T1666 |
Fludrocortisone acetate
|
9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,9α-fluorocortisol acetate |
Glucocorticoid Receptor
,
Autophagy
|
|
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-respon... |
|
T1127 |
Beclometasone dipropionate
|
Beclovent,Beclomethasone dipropionate,Beconase,Vancenase |
Glucocorticoid Receptor
|
|
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone... |
|
T0820 |
Triamcinolone acetonide
|
Aristogel,Azmacort,Aristoderm |
Glucocorticoid Receptor
|
|
Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the ... |
|
T0272 |
Nilutamide
|
RU23908 |
Androgen Receptor
|
|
Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto... |
|
T41303 |
Isoflupredone
|
Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone |
Others
|
|
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio... |
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T27152 |
Dexamethasone Beloxil
|
|
|
|
Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent. |
|
T25264 |
Cloprednol
|
Novacort,Cloradryn,RS-4691,RS 4691,Syntestan |
|
|
Cloprednol is a synthetic glucocorticoid. It has an anti-inflammatory potency twice that of prednisone. |
|
T31060 |
CP-472555
|
UNII-6T0KV7024R,CP 472555,CP472555 |
|
|
CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models. |
|
T21192 |
Diflorasone Diacetate
|
Apexicon E,Psorcon,Maxiflor,Florone E |
|
|
Diflorasone Diacetate, a topical glucocorticoid, has immunosuppressive and anti-inflammatory properties. |
|
T13200 |
Triamcinolone Benetonide
|
|
Others
|
|
Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid exhibiting potent anti-inflammatory properties. |
|
T40697 |
Glucocorticoids receptor agonist 2
|
|
|
|
Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflamma... |
|
T32113 |
Hydrocortamate Hydrochloride
|
UNII-9QM8U7R83W,Ulcort,Hydrocortamate HCl,Magnacort,Ethamicort |
|
|
Hydrocortamate Hydrochloride is a synthetic glucocorticoid that has anti-inflammatory and immunosuppressive properties. It is used topically to treat inflammation caused by corticosteroid-responsive skin diseases. |
|
T71346 |
MS4
|
|
|
|
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets. |
|
T16404 |
ORIC-101
|
|
|
|
ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity. |
|
T1018 |
Prednisone
|
Dehydrocortisone |
Apoptosis
,
Glucocorticoid Receptor
,
MRP
|
|
Prednisone (Dehydrocortisone) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. |
|
T63551 |
Glucocorticoid receptor-IN-1
|
|
|
|
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:... |
|
T63539 |
Glucocorticoid receptor-IN-2
|
|
|
|
Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 n... |
|
T33883 |
Paramethasone Acetate
|
NCGC00185748-01,Monocortin,CHEBI:31963,8X50N88ZDP,UNII-8X50N88ZDP |
Others
|
|
Paramethasone Acetate is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive effects that can be used in the treatment of systemic lupus erythematosus. |
|
T75016 |
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal
|
|
|
|
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring... |
|
T17291 |
ZK 216348
|
(+)-ZK 216348 |
Others
|
|
ZK 216348 also binds to Progesterone and mineralocorticoid receptors (IC50s: 20.4 nM and 79.9 nM, respectively). ZK 216348 is a nonsteroidal selective glucocorticoid receptor agonist (IC50: 20.3 nM). ZK 216348 has an an... |
|
T68877 |
Tetrahydrocorticosterone
|
|
|
|
Tetrahydrocorticosterone (THB) is a glucocorticoid (GC) that has anti-inflammatory functions. For instance, 5α THB inhibits inflammatory actions by binding to GC receptor. HPLC studies in rat brains have reported that te... |
|
T40808 |
Glucocorticoids receptor agonist 1
|
|
|
|
Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining i... |
|
T74697 |
Glucocorticoid receptor agonist-2
|
|
|
|
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of an... |
|
T77869 |
Glucocorticoid receptor agonist-2 Ala-Ala-Mal
|
|
|
|
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1]. |
|
T75130 |
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
|
|
|
|
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1]. |
