|
T0343 |
Nimodipine
|
BAY-e 9736 |
Glucocorticoid Receptor
,
AhR
,
Calcium Channel
,
Autophagy
|
|
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. |
|
T15047 |
Dacisteine
|
N,S-Diacetyl-L-cysteine |
Others
|
|
Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM). |
|
T0005 |
Aspirin
|
Acetylsalicylate,Acetylsalicylic Acid,ASA |
Mitophagy
,
Virus Protease
,
COX
,
Autophagy
|
|
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel... |
|
T0368 |
Cinepazide maleate
|
MD-67350,Vasodistal,Brendil |
Calcium Channel
|
|
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator. |
|
T72501 |
CYP4A11/CYP4F2-IN-1
|
|
P450
|
|
CYP4A11/CYP4F2-IN-1 is a cytochrome P450 (CYP) 4A11 and CYP4F2 inhibitor. CYP4A11/CYP4F2-IN-1 can be used to study kidney diseases and cardiovascular and cerebrovascular diseases. |
|
T6236 |
Ozagrel
|
OKY-046,Domenan |
Thrombin
,
Prostaglandin Receptor
|
|
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch... |
|
T16897 |
SM-6586
|
|
Na+/Ca2+ Exchanger
,
Sodium Channel
|
|
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases. |
|
T6625 |
Ozagrel hydrochloride
|
Ozagrel HCl,OKY-046 HCl |
Thrombin
,
Prostaglandin Receptor
|
|
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. |
|
T0183 |
Pramiracetam
|
CI-879 |
Others
|
|
Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t... |
|
T21389 |
Enprofylline
|
Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum |
Others
|
|
Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick... |
|
T0182L2 |
(±) Clopidogrel hydrogen sulfate
|
Plavix,Clopidogrel hydrogen sulfate,Iscover |
P2Y Receptor
|
|
(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph... |
|
T28778 |
Silperisone HCl
|
RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336 |
|
|
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi... |
|
T11043 |
Dihydroergocristine mesylate
|
DHEC (mesylate) |
Beta Amyloid
|
|
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebro... |
|
T70682 |
AJ-3941
|
|
|
|
AJ-3941 is a cerebrovascular-selective Ca2+ channel antagonist with anti-lipid peroxidative action. AJ-3941 may be useful in the treatment of cerebrovascular disorders. |
|
T6236L |
Ozagrel Sodium
|
KCT 0809,KCT-0809,Xanbo,KCT0809,Cataclot |
|
|
Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases. |
|
T0368L |
Cinepazide
|
Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562 |
|
|
Cinepazide is a vasodilator used for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases. Cinepazide acts as a potentiator of adenosine A2 receptors. |
|
T11448 |
GOAT-IN-1
|
|
Others
|
|
|
|
T36092 |
Fenobucarb
|
|
|
|
Fenobucarb, a widely employed carbamate insecticide, poses potential risks to the cardiovascular and cerebrovascular systems in animals[1][2]. It triggers developmental neurotoxicity in zebrafish by engaging pathways rel... |
|
T38149 |
β-Amyloid (1-43)(human)
|
|
|
|
The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor ... |
|
T62351 |
Lotrafiban
|
|
|
|
Lotrafiban is an orally active platelet membrane glycoprotein IIb/IIIa blocker that can be used in the treatment of coronary heart disease and cerebrovascular disease. |
|
T17231 |
Vicagrel
|
|
Others
|
|
Vicagrel is an effective, orally active antiplatelet compound that enhances the inhibitory effect of aspirin on platelet aggregation and thrombosis in rodents by irreversibly inhibiting P2Y12 receptors and reducing metab... |
|
T72040 |
C-Myc inhibitor 7
|
|
|
|
C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research i... |
