|
T17115 |
Tolycaine
|
|
|
|
Tolycaine is a compound of local anesthetic. |
|
T19644 |
Benzonatate
|
|
Sodium Channel
|
|
Benzonatate is an antagonist of sodium channel protein. |
|
T23070 |
Nisoxetine hydrochloride
|
|
Sodium Channel
,
Monoamine Transporter
,
Norepinephrine
|
|
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor |
|
T6443 |
Chloroprocaine hydrochloride
|
Chloroprocaine HCl |
ATPase
,
Others
|
|
Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures. |
|
T0222 |
Proparacaine hydrochloride
|
Proparacaine HCl,Proxymetacaine Hydrochloride |
Apoptosis
,
Sodium Channel
|
|
Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride (Proparacaine HCl) stabilizes the neuronal membrane by bindi... |
|
T0946 |
Mepivacaine hydrochloride
|
Mepivacaine HCl |
Sodium Channel
|
|
Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties. |
|
T0072 |
Adiphenine hydrochloride
|
Adiphenine HCl,Spasnil,Patrovina,Sentiv |
AChR
|
|
Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug. |
|
T0314 |
Hexylresorcinol
|
4-Hexylresorcinol |
Apoptosis
,
Tyrosinase
,
Antibacterial
,
Parasite
|
|
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. |
|
T1389 |
Dyclonine hydrochloride
|
Dyclocaine hydrochloride,Dyclonine HCl |
Sodium Channel
,
Antibacterial
,
Antifungal
|
|
Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect . |
|
T2568 |
Felypressin
|
Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2 |
Vasopressin Receptor
|
|
Felypressin (Octapressin) is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity. |
|
T0703 |
Flavoxate hydrochloride
|
Flavoxate HCl,NSC-114649,DW61,Rec-7-0040 |
AChR
|
|
Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic. |
|
T2568L |
Felypressin acetate
|
2-(L-Phenylalanine)-8-L-lysinevasopressin,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2 |
Vasopressin Receptor
|
|
Felypressin acetate (PLV-2) is an agonist of vasopressin 1 and acts on all arginine vasopressin receptors 1AS. Felypressin acetate can be used in dental procedures. |
|
T0325 |
Diperodon hydrochloride
|
Diothane hydrochloride,Proctodon,Diperocaine |
Others
|
|
Diperodon hydrochloride (Diperocaine) is a local anesthetic that can be broken down by serolytic enzymes to produce local anesthetic effects. |
|
T31716 |
Etidocaine Hydrochloride
|
W-19053,Duranest,W19053,W 19053 |
Sodium Channel
|
|
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel. |
|
T24451 |
Mepyramine
|
NSC-13136,NSC13136,NSC 13136 |
|
|
Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally. |
|
T16558 |
Polidocanol
|
Polyoxyethylene lauryl ether,Polyoxyethyleneglycol Dodecyl Ether |
Others
|
|
Polidocanol (Polyoxyethylene lauryl ether) is an alkyl polyethylene glycol ether of lauryl alcohol, which is a derivative of natural fatty or alkyl alcohols in natural mineral oil and is a hardener. Polidocanol can be us... |
|
T9397 |
Parethoxycaine hydrochloride
|
2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride,Diethoxin |
Others
|
|
Parethoxycaine hydrochloride (2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride) is an anesthetic[1]. |
|
T2131 |
Articaine hydrochloride
|
Ultracaine,Articaine HCl,Hoe-045 |
Sodium Channel
|
|
Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE. |
|
T0364 |
Dibucaine
|
Cinchocaine |
CaMK
,
Sodium Channel
,
AChR
|
|
Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia. |
|
T34146 |
Propanidid
|
FBA 1420,Epontol,Sombrevin,Fabontal,Fabantol |
GABA Receptor
|
|
Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and a fast-acting intravenous anesthetic that lowers arterial blood pressure. |
|
T0916 |
Butamben
|
Butyl 4-aminobenzoate |
Potassium Channel
,
Calcium Channel
,
Sodium Channel
|
|
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain. |
|
T31716L |
Etidocaine
|
|
Others
|
|
Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties. |
|
T28829 |
Soquinolol
|
Soquinolol mucate |
Adrenergic Receptor
|
|
Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a long duration of action. |
|
T0924 |
Benzocaine
|
|
Others
,
MRP
,
Sodium Channel
|
|
Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
|
T34154 |
Propoxate
|
R 7464,R7464,R-7464 |
Others
|
|
Propoxate (R7464) is a potent anesthetic that can be used to anesthesiate cold-blooded vertebrates. |
|
T19897 |
Anavenol
|
2-(naphthalen-2-yloxy)ethanol |
Others
|
|
Anavenol (2-(naphthalen-2-yloxy)ethanol) is an equine anesthetic. |
|
T0044 |
Oxethazaine
|
Oxetacaine |
HBV
,
Sodium Channel
|
|
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain. |
|
T15653 |
Ketocaine
|
Rec 7-0518 |
Others
|
|
Ketocaine（Rec 7-0518） is a local anesthetic commonly used in animal experiments with potential antitumor activity for pain relief. |
|
T1144L |
Lidocaine Hydrochloride hydrate
|
|
EGFR
,
Sodium Channel
|
|
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property. |
|
T21483 |
Tricaine methanesulfonate
|
MS-222 |
Others
|
|
Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures. |
|
T0460 |
Pramocaine hydrochloride
|
Pramoxine hydrochloride,Pramoxine HCl |
Sodium Channel
|
|
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic. |
|
T19651 |
Isoflurane
|
HSDB-8057,Forane,HSDB 8057,HSDB8057,Terrell |
Others
|
|
Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation. |
|
T0386 |
Ropivacaine hydrochloride
|
Ropivacaine monohydrochloride |
Potassium Channel
,
Sodium Channel
|
|
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. |
|
T7118 |
Dimethocaine
|
Larocaine |
Others
,
Dopamine Receptor
|
|
Dimethocaine (Larocaine) is a local anesthetic which also effects on the central nervous system acting as dopamine-reuptake-inhibitor. |
|
T68165 |
Trapencaine
|
|
|
|
Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes. |
|
T0378 |
Oxybuprocaine hydrochloride
|
Risedronic Acid,Oxybuprocaine HCl |
Sodium Channel
|
|
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology. |
|
T6566 |
Levobupivacaine hydrochloride
|
Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride |
Sodium Channel
|
|
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic... |
|
T0796 |
Prilocaine hydrochloride
|
Prilocaine HCl,Propitocaine hydrochloride,Xylonest |
ATPase
,
Sodium Channel
|
|
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. |
|
T0029 |
Procaine
|
Duracaine,Spinocaine,Novocaine,Vitamin H3 |
Histone Demethylase
,
DNA/RNA Synthesis
,
Sodium Channel
|
|
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. |
|
T0954 |
Halothane
|
Narcotane,Anestan |
Potassium Channel
,
Chloride channel
,
GABA Receptor
,
NMDAR
|
|
Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly.... |
|
T6953 |
Prilocaine
|
Citanest,Propitocaine,NSC 40027 |
ATPase
,
Sodium Channel
|
|
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures. |
|
T1098 |
Denatonium benzoate
|
THS-839 |
Others
|
|
Denatonium benzoate (THS-839) , a quaternary ammonium cation, is a compound of a salt with an inert anion like saccharide or benzoate. Its structure is involved in the local anesthetic lidocaine which difference only is ... |
|
T1232 |
Mepyramine maleate
|
Pyrilamine maleate |
Histamine Receptor
|
|
Mepyramine maleate (Pyrilamine maleate) is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. I... |
|
T1144 |
Lidocaine hydrochloride
|
Lidocaine HCL,Lignocaine hydrochloride,Xyloneural,Lidothesin |
Apoptosis
,
ERK
,
NF-κB
,
MEK
,
Sodium Channel
|
|
Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its ... |
|
T22371 |
Mivacurium dichloride
|
Mivacurium chloride |
AChR
|
|
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg... |
|
T0030 |
Bupivacaine hydrochloride
|
Vivacaine,Bupivacaine HCl |
Sodium Channel
|
|
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol... |
|
T0802 |
Procaine hydrochloride
|
Novocaine HCl,Procaine HCl |
Histone Demethylase
,
5-HT Receptor
,
DNA/RNA Synthesis
,
Sodium Channel
,
NMDAR
,
AChR
|
|
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... |
|
T0468 |
Lidocaine
|
Lignocaine,Alphacaine,Xylocaine |
Apoptosis
,
ERK
,
NF-κB
,
MEK
,
Sodium Channel
,
Histamine Receptor
|
|
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammat... |
|
T1320 |
Disopyramide
|
Triombrin,Hypaque sodium,amidotrizoate sodium |
Potassium Channel
,
Sodium Channel
,
AChR
|
|
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the h... |
|
T30109 |
Aptocaine
|
|
|
|
Aptocaine is a local anesthetic. |
