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Search Results for " lineage "

ターゲット

ROCK MLK VEGFR SGK DNA Alkylation Trk receptor c-Met/HGFR LRRK2 MEK IGF-1R Syk Bcr-Abl CDK Src Aurora Kinase Autophagy

阻害剤

天然化合物

136

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T6057	URMC-099		ROCK , MLK , VEGFR , SGK , DNA Alkylation , Trk receptor , c-Met/HGFR , LRRK2 , MEK , IGF-1R , Syk , Bcr-Abl , CDK , Src , Aurora Kinase , Autophagy
	URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
T6904	Necrosulfonamide	(E)-Necrosulfonamide	MLK
	(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec...		MLK
T11520	GW806742X		MLK , VEGFR
	GW806742X is an inhibitor of Mixed Lineage Kinase Domain-Like protein (MLKL) which binds the MLKL pseudokinase domain (Kd: 9.3 μM) with anti-necroptosis activity. GW806742X has activity against VEGFR2.		MLK , VEGFR
T9399	Menin-MLL inhibitor 20		Epigenetic Reader Domain , Histone Methyltransferase
	Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.		Epigenetic Reader Domain , Histone Methyltransferase
T1725	Y-27632 dihydrochloride	Y-27632 2HCl	ROCK , Apoptosis
	Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.		ROCK , Apoptosis
T3082	SGC0946		Histone Methyltransferase
	SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.		Histone Methyltransferase
T11925	M‑89		Epigenetic Reader Domain , Histone Methyltransferase
	M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia...		Epigenetic Reader Domain , Histone Methyltransferase
T77245	Mannan		Endogenous Metabolite
	Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live...		Endogenous Metabolite
T6825	Eltrombopag Olamine	Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR	Thrombin
	Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...		Thrombin
T8768	MM-102 TFA	HMTase Inhibitor IX TFA	Histone Methyltransferase
	MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM. MM-102 compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WD...		Histone Methyltransferase
T36944	Ara-G		Nucleoside Antimetabolite/Analog
	Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...		Nucleoside Antimetabolite/Analog
T24471	MIV-6
	MIV-6 is an inhibitor of the menin-mixed lineage leukemia interaction.
T17010	TC13172		Others
	TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2 nM for HT-29 cells).		Others
T12091	MM-589		JAK
	MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.		JAK
T78151	Bleximenib oxalate	Menin-MLL inhibitor 24 oxalate	Epigenetic Reader Domain
	Menin-MLL Inhibitor 24 (compound A) oxalate, a menin-mixed-lineage leukemia 1 (menin-MLL) inhibitor, is utilized in cancer research [1].		Epigenetic Reader Domain
T71620	IBAP-II
	iBAP-II represses neuroendocrine lineage-specific ASCL1/MYCL/E2F signaling in SCLC cell lines, and dramatically inhibits SCLC cell viability and tumor growth in vivo.
T12091L	MM-589 TFA		JAK
	MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.		JAK
T26887	BOP
	BOP is anantagonist of alpha4beta1/alpha9beta1 integrins. BOP rapidly mobilizes long-term multi-lineage reconstituting hematopoietic stem cells (HSC).
T12002	Menin-MLL inhibitor 4		Others
	Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .		Others
T39102	MLK-IN-1
	MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3.
T34604	Selenodicysteine
	Selenodicysteine is the 21st proteinogenic amino acid. Selenocysteine exists naturally in all three domains of life, but not in every lineage.
T79731	MLKL-IN-6		Necroptosis
	MLKL-IN-6 (compound P28) is a mixed lineage kinase inhibitor that specifically targets the Mixed Lineage Kinase domain-like (MLKL) protein. It effectively prevents MLKL phosphorylation and oligomerization, which are crit...		Necroptosis
T70677	PLS-123
	PLS-123 is a novel covalent irreversible Btk inhibitor with potential anti-proliferative activity. PLS-123 exhibited more potent anti-proliferative effects than ibrutinib in multiple cellular and in vivo preclinical mode...
T79899	Cbl-b-IN-12		E1/E2/E3 Enzyme
	Cbl-b-IN-12 (Example 10) is an inhibitor of casitas B-lineage lymphoma-b (CBL-B), demonstrating a half-maximal inhibitory concentration (IC50) of less than 100 nM [1].		E1/E2/E3 Enzyme
T79895	Cbl-b-IN-8		E1/E2/E3 Enzyme
	Cbl-b-IN-8 (Compound 293) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].		E1/E2/E3 Enzyme
T79894	Cbl-b-IN-7		E1/E2/E3 Enzyme
	Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].		E1/E2/E3 Enzyme
T79897	Cbl-b-IN-10		E1/E2/E3 Enzyme
	Cbl-b-IN-10 (Compound 463) is a potent inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.0 nM and 3.5 nM, respectively [1].		E1/E2/E3 Enzyme
T79898	Cbl-b-IN-11		E1/E2/E3 Enzyme
	Cbl-b-IN-11 (Compound 466) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.4 nM and 6.1 nM, respectively [1].		E1/E2/E3 Enzyme
T79893	Cbl-b-IN-6		E1/E2/E3 Enzyme
	Cbl-b-IN-6 (Compound 246) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM for Cbl-b and 5.2 nM for c-Cbl, respectivel...		E1/E2/E3 Enzyme
T70593	GW-841819X
	GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X displayed activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia. Br...
T79896	Cbl-b-IN-9		E1/E2/E3 Enzyme
	Cbl-b-IN-9 (Compound 300) is an inhibitor targeting casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting potent inhibitory activity with half-maximal inhibitory concentrations (IC50s) of 5.6 nM and 4.7 nM, respecti...		E1/E2/E3 Enzyme
T28630	RX-37	RX37
	RX-37 is a potent BET inhibitor with Ki values of 3.2-24.7 nM for BRD2, BRD3 and BRD4. RX-37 demonstrates high selectivity over other non-BET bromodomain-containing proteins. RX-37 potently and selectively inhibits cell ...
T69624	TC-5115
	TC-5115 is a potent inhibitor of MLL methyltransferase with IC50 value of 16 nM. TC-5115 may lead to the development of a new therapy for the treatment of human MLL leukemia. The mixed-lineage leukemia (MLL) protein, al...
T78904	Anticancer agent 110		Apoptosis
	Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations. It induces DNA damage and subseq...		Apoptosis
T76052	ELA-32(human) TFA
	ELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, ...
T69014	Sekikaic Acid
	Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µ...
T69629	M‑89 MLL inhibitor
	M‑89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein−Protein Interaction (Kd = 1.4 nM; IC50 = 25nM). M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular men...
T82763	CD33 splicing modulator 1 hydrochloride
	CD33 Splicing Modulator 1 Hydrochloride (Compound 1) is a myeloid lineage cell surface receptor CD33/Siglec 3 modulator involved in regulating microglia activity. This compound promotes exon 2 skipping in cellular mRNA p...
T74681	NecroIr2
	NecroIr2, an iridium(III) complex, functions as a necroptosis inducer in cisplatin-resistant lung cancer cells (A549R). It preferentially accumulates in mitochondria, causing oxidative stress and a reduction in mitochond...
T74680	NecroIr1
	NecroIr1, an iridium(III) complex, acts as a necroptosis inducer in Cisplatin-resistant lung cancer cells (A549R). It selectively targets mitochondria, causing oxidative stress and reducing mitochondrial membrane potenti...
T82598	DDO-2213
	DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5. It selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase ...
TP2097	ELA-32(human)	ELA-32 (human)
	Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein ...
T64072	Cbl-b-IN-2
	Cbl-b-IN-2 is an orally active biological compound that inhibits the E3 enzyme Casitas b lineage lymphoma proto-oncogene b (Cbl-b) in the ubiquitin proteasome pathway and can be used in the study of diseases that modulat...
T36574	GW841819X	GW841819X
	GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X was a single enantiomer but of undefined chirality at the 4-position of the benzodiazepine ring3. GW841819X and JQ1 were recently d...

Compounds

URMC-099

T6057

Synonym:

Target: ROCK, MLK, VEGFR, SGK, DNA Alkylation, Trk receptor, c-Met/HGFR, LRRK2, MEK, IGF-1R, Syk, Bcr-Abl, CDK, Src, Aurora Kinase, Autophagy

Necrosulfonamide

T6904

Synonym: (E)-Necrosulfonamide

Menin-MLL inhibitor 20

T9399

Synonym:

Target: Epigenetic Reader Domain, Histone Methyltransferase

Y-27632 dihydrochloride

T1725

Synonym: Y-27632 2HCl

Target: ROCK, Apoptosis

SGC0946

T3082

Synonym:

Target: Histone Methyltransferase

M‑89

T11925

Synonym:

Target: Epigenetic Reader Domain, Histone Methyltransferase

Mannan

T77245

Synonym:

Target: Endogenous Metabolite

Eltrombopag Olamine

T6825

Synonym: Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR

Target: Thrombin

MM-102 TFA

T8768

Synonym: HMTase Inhibitor IX TFA

Target: Histone Methyltransferase

Ara-G

T36944

Synonym:

Target: Nucleoside Antimetabolite/Analog

Synonym: Menin-MLL inhibitor 24 oxalate

Target: Epigenetic Reader Domain

Menin-MLL inhibitor 4

Target: E1/E2/E3 Enzyme

Cbl-b-IN-8

T79895

Synonym:

Target: E1/E2/E3 Enzyme

Cbl-b-IN-7

T79894

Synonym:

Target: E1/E2/E3 Enzyme

Cbl-b-IN-10

T79897

Synonym:

Target: E1/E2/E3 Enzyme

Cbl-b-IN-11

T79898

Synonym:

Target: E1/E2/E3 Enzyme

Cbl-b-IN-6

T79893

Synonym:

Target: E1/E2/E3 Enzyme

Target: E1/E2/E3 Enzyme

CD33 splicing modulator 1 hydrochloride

Synonym: ELA-32 (human)

カタログ番号	製品名	別名	ターゲット
T75661	Thymopentin acetate
	Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...

天然物製品

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01393	PGCP Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides w...
TMPY-04735	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His)	WNV	HEK293
	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 42.1 kDa. Accession number: YP_001527881.1
TMPJ-00515	HCLS1 Protein, Human, Recombinant (His)	Human	Human Cells
	Hematopoietic lineage cell-specific protein (HCLS1) is a protein that in humans is encoded by the HCLS1 gene. It is expressed only in tissues and cells of hematopoietic origin. It is substrate of the antigen receptor-cou...
TMPY-04299	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His)	WNV	Yeast
	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His) is expressed in Yeast with His tag. The predicted molecular weight is 12.9 kDa. Accession number: ABA62343.1
TMPY-04787	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His)	WNV	Yeast
	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His) is expressed in Yeast with His tag. The predicted molecular weight is 12.9 kDa. Accession number: AED99787.1
TMPY-06467	SARS-CoV-2 (B.1.1.529 sublineage BA.2) Spike S1 Protein (His)	SARS-CoV-2	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-06335	SARS-CoV-2 B.1.1.529 sublineage BA.2 (Omicron) Spike RBD Protein (His)	SARS-CoV-2	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-06473	SARS-CoV-2 (B.1.1.529 sublineage BA.2) Nucleocapsid Protein (His)	SARS-CoV-2	E. coli
	Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi...
TMPJ-00235	TPO Protein, Human, Recombinant (His)	Human	Human Cells
	Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPY-00464	M-CSF/CSF1 Protein, Mouse, Recombinant	Mouse	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-01883	EPOR Protein, Human, Recombinant (His)	Human	HEK293
	Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific ...
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His)	Human	HEK293
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPY-03947	CD48 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPY-01302	CD200R Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02268	CD93/C1qR1 Protein, Human, Recombinant (His)	Human	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06844	CD93/C1qR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06027	CD93/C1qR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-04951	CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated	Human	Baculovirus-Insect Cells
	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a typ...
TMPY-00716	CD89 Protein, Human, Recombinant (His)	Human	HEK293
	FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This recep...
TMPY-03401	CD27/TNFRSF7 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a typ...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPH-00081	CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	Yeast
	Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear numbe...
TMPH-01824	PAX5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineag...
TMPY-01299	GMF gamma/GMFG Protein, Human, Recombinant (His)	Human	E. coli
	The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality...
TMPJ-01365	SLAMF8 Protein, Human, Recombinant (His)	Human	Human Cells
	SLAM family member 8 (SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type domain. SLAMF8 is a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These protei...
TMPK-00590	IL-3 Protein, Human, Recombinant（E. coli）	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00049	IL-3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00655	IL-3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00031	IL-3 Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00033	IL-3 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00032	IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00622	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-01305	CD43 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events...
TMPK-00624	CD200R1/CRTR2 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-00832	CD43 Protein, Human, Recombinant (His)	Human	HEK293
	CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events...
TMPK-00700	KIR2DL5 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ance...
TMPK-00701	KIR2DL5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ance...
TMPY-01664	FcRH1/FCRL1 Protein, Human, Recombinant (His)	Human	HEK293
	Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which ...
TMPK-00623	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-01262	CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPY-03075	FcRH1/FCRL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which ...
TMPY-02810	Ninjurin-1 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia c...
TMPK-00827	CD43 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing, activation of Foxp3 Treg, and T cell apoptosis. ...
TMPH-02190	Tescalcin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at...
TMPJ-00364	LRRC32 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency a...
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-04229	M-CSF/CSF1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
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