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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T83671 | CCP-biotin Peptide (non-cyclized) | Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized) | |
CCP-biotin peptide (non-cyclized) is a linear, biotin-labeled derivative of the circular citrullinated peptide (CCP), mirroring the human filaggrin sequence from amino acids 447 to 467 with specific substitutions (Q447H,... | |||
T3474 | RO 46-8443 | Endothelin Receptor | |
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition. | |||
T2561 | Macitentan | ACT-064992 | Apoptosis , Endothelin Receptor |
Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH). | |||
TP1253 | Argireline | Acetyl hexapeptide-3 | Others |
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argirelin... | |||
T12895 | SHA 68 | Neuropeptide Y Receptor | |
TP2204L | CCK Octapeptide, non-sulfated acetate | CCK Octapeptide, non-sulfated acetate(25679-24-7 Free base) | cholecystokinin |
CCK Octapeptide, non-sulfated acetate is a synthetic desulfated peptide of cholecystokinin. | |||
T35085 | VUF-11222 | VUF 11222 | |
VUF-11222 is an agonist of high affinity non-peptide CXCR3 agonist (pKi = 7.2). | |||
T26645 | Aptiganel | CNS 1102,CNS-1102,CNS1102 | NMDAR |
Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke. | |||
T4355 | Fuscoside | OPC 21268 | Vasopressin Receptor |
Fuscoside (OPC 21268) is a non-peptide Arginine vasopressin(AVP) Receptor V antagonist. | |||
T2537 | Tirofiban hydrochloride monohydrate | Tirofiban Hydrochloride,MK-383 Hydrochloride | ATPase , Integrin |
Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist. | |||
T12293L | Olcegepant | BIBN-4096,BIBN 4096BS | CGRP Receptor |
Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP). | |||
T2375 | BX471 | BX 471,BX-471,ZK-811752 | CCR |
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist. | |||
T68068L | (R)-CJ 11974 | Neurokinin receptor | |
(R)-CJ 11974 is a novel non-peptide neurokinin NK1 substance P receptor antagonist with potential analgesic activity that can be used to study chemotherapy-induced vomiting. | |||
T35233 | Y-29794 Tosylate | Y 29794,Y29794 tosylate,Y29794,Y-29794 | Prolyl Endopeptidase (PREP) |
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor. | |||
T4540 | ML-18 | Bombesin Receptor | |
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM. | |||
T6658 | SB-408124 | OX Receptor | |
SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor. | |||
T8559 | Galnon TFA(475115-35-6(free base)) | Neuropeptide Y Receptor | |
Galnon is a novel non-peptide galanin receptor agonist (GAL1 and GAL2 with Ki of 11.7 and 34.1 μM respectively). | |||
T7112 | Ibutamoren Mesylate | MK-0677,MK-677 | GHSR |
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. | |||
T5048 | SSR240612 | Bradykinin Receptor | |
SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively). | |||
T69140 | Burapitant | SSR 240600 | Neurokinin receptor |
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity. | |||
T16854 | SB-674042 | SB674042 | OX Receptor |
SB-674042 is a potent and selective dual antagonist of the non-peptide orexigenic peptides OX1 and OX2 receptors, with IC50s of 3.76 nM and 531 nM, respectively.SB-674042 can be used for the treatment of depression. | |||
TP1887L1 | [Ala107]-MBP (104-118) acetate | [Ala107]-MBP (104-118) acetate(99026-77-4 free base) | PKC |
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM). | |||
T25742 | Linzagolix choline | GNRH Receptor | |
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibroids and endometriosis. | |||
T15387 | GLP-1R Antagonist 1 | Glucagon Receptor | |
GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM). | |||
T3194 | Ro 46-2005 | Endothelin Receptor | |
Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM). | |||
T16430 | Paliroden | SR 57667,SR 57667B | Others |
Paliroden is a non-peptide compound that can be taken orally and is used for supplementing neuro-nutrition. It stimulates the synthesis of endogenous neurotrophic factors and is employed in the research of neurodegenerat... | |||
T2322 | Fimasartan | BR-A-657,Kanarb | Apoptosis , RAAS |
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has show... | |||
T17250 | W-54011 | ROS , Complement System | |
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g... | |||
T12384 | PD 90780 | Others | |
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC1... | |||
T11861 | LM11A-31 dihydrochloride | Others | |
LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni... | |||
T27837 | Linzagolix | GNRH Receptor | |
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,... | |||
T25616 | Lanepitant 2HCl | LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride | Neurokinin receptor |
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam... | |||
T16766 | Ro 08-2750 | ||
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2... | |||
T21871 | MMPSI | Caspase-3/7 Inhibitor I | Apoptosis , Caspase |
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a ... | |||
T8414 | SNC 80 | Snc-80,SNC80,NIH 10815 | Opioid Receptor |
SNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 show... | |||
T67894 | Butyzamide | Thrombopoietin Receptor , JAK | |
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mou... | |||
T3360 | ZK 756326 | ZK756326 2HCl | CCR |
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less ... | |||
TP1565L1 | Foxy-5 Ammonium Salt | Foxy-5 Ammonium Salt(881188-51-8 Free base) | Wnt/beta-catenin |
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in... | |||
T15368L | Galantide acetate | Galantide acetate(138579-66-5 Free base) | Neuropeptide Y Receptor |
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in t... | |||
T3630 | Relugolix | RVT-601,TAK-385 | GNRH Receptor |
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi... | |||
T70521 | CGP-49823 | ||
CGP-49823 is a non-peptide tachykinin NK1 receptor antagonist. | |||
TP2162 | D-JBD19 | Others | |
D-JBD19 is a non-permeable peptide with neuroprotective effects. | |||
T32499 | L-692429 HCl | L692,429,L-692429,L 692429,L-692,429,L692429,L 692,429 | |
L-692,429 is a novel non-peptide growth hormone secretagin. | |||
T71277 | Amiglumide | ||
Amiglumide is a non-peptide cholecystokinin antagonist. | |||
T27666 | JNJ-19567470 | JNJ19567470 | |
JNJ-19567470 is a selective, non-peptide CRF receptor 1 antagonist. | |||
T34784 | TAN67 | SB-205607 dihydrobromide,SB 205607 dihydrobromide,SB205607 dihydrobromide,TAN-67,TAN 67 | |
TAN67 is the first effective selective non-peptide delta1 opioid receptor. | |||
T70101 | EMD-66684 | ||
EMD-66684 is a non-peptide angiotensin II receptor antagonist. | |||
T70416 | PD 154075 | ||
PD 154075 is a a non-peptide tachykinin NK1 receptor antagonist. | |||
T33755 | NSC57971 | ||
NSC57971 is a novel non-peptide interference of the IKKß/NEMO complex. | |||
T24065 | FK-3657 | FK 3657,FK3657,FR-173657,FR 173657,FR173657 | |
FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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TN1849 | Kuwanon H | GPR , Bombesin Receptor | |
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP. | |||
T37526 | 2-Oleoylglycerol | 2-Oleoyl Glycerol,2-OG,2-Monoolein | GPR |
2-Oleoylglycerol is a lipid found in palm kernel, sunflower seed and rice bran.2-Oleoylglycerol acts as a GPR119 agonist with neuroprotective effects and induces secretion of glucagon-like peptide 1 (GLP-1).2-Oleoylglyce... | |||
T5306 | H-Abu-OH | L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid | Others , Endogenous Metabolite |
H-Abu-OH (L-α-amino-n-Butyric acid) , also known as (S)-2-aminobutanoic acid, homoalanine, 2-AABA, ethylglycine, or L-butyrine, is a member of the class of compounds known as L-alpha-amino acids. H-Abu-OH is a non-proteo... | |||
T4788 | L-Norvaline | Others , Endogenous Metabolite | |
L-Norvaline is an arginase inhibitor and a non-proteinogenic branched-chain amino acid. L-Norvaline has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. L-Norvaline and ot... | |||
T62625 | 11-O-Methylpseurotin A | ||
11-O-Methylpseurotin A, a mixed polyketide synthase-non-ribosomal peptide synthase (PKS/NRPS) compound, selectively inhibited Hof1-deficient strains. | |||
T11009 | Destruxin B | Others | |
Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through t... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPJ-00695 | CuTA Protein, Human, Recombinant (His) | Human | E. coli |
Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a bro... | |||
TMPK-00501 | PADI4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti... | |||
TMPK-00502 | PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated | Cynomolgus | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti... | |||
TMPK-01238 | PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti... | |||
TMPJ-00773 | TUBB4A Protein, Human, Recombinant (His) | Human | E. coli |
Tubulin Beta-4A Chain (TUBB4A) is a cytoplasmic peptide containing 444 amino acids. TUBB4A is a member of the Tubulin family. Tubulin is the major constituent of microtubules. Tubulin is a dimer composed of one alpha and... | |||
TMPY-02682 | NELL2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
A brain-enriched secreting signal peptide, NELL2, has been suggested to play multiple roles in the development, survival, and activity of neurons in the mammal. NELL2 is an abundant glycoprotein containing an EGF-like do... | |||
TMPH-01640 | MRGPRX2 Protein, Human, Recombinant (His) | Human | E. coli |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ... | |||
TMPJ-00022 | LGALS7 Protein, Human, Recombinant | Human | E. coli |
The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also poss... | |||
TMPH-00708 | DegP Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo... | |||
TMPJ-01089 | TFF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing... | |||
TMPJ-00812 | HBQ1 Protein, Human, Recombinant (His) | Human | E. coli |
Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is originally found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. Theta-1 i... | |||
TMPJ-00526 | Langerin/CD207 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the e... | |||
TMPJ-00654 | LGALS8 Protein, Human, Recombinant | Human | E. coli |
The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also poss... | |||
TMPH-02173 | TRBC2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe... | |||
TMPH-02168 | TRAC Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p... | |||
TMPH-02169 | TRBC1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe... | |||
TMPH-02275 | Lck Protein, Human, Recombinant (His) | Human | E. coli |
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TC... | |||
TMPK-01505 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... | |||
TMPK-01492 | HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i... | |||
TMPK-01501 | HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i... | |||
TMPK-01491 | HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i... | |||
TMPK-01504 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... | |||
TMPK-01506 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... |