| S00015 |
Tea polyphenol
|
|
Apoptosis
,
Others
,
Autophagy
|
|
Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing c... |
| T3921 |
Punicalagin
|
|
SARS-CoV
,
HBV
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Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula... |
| T2S2108 |
Coixol
|
6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA |
Others
,
Antibacterial
|
|
1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo... |
| TN7104 |
(+)-Epicatechin
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Dexepicatechin |
Others
|
|
(+)-Epicatechin (Dexepicatechin) is a natural product and an antioxidant agent. |
| T2807 |
Caffeic Acid
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Lipoxygenase
,
Endogenous Metabolite
,
TRP/TRPV Channel
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Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities. |
| T6427 |
Butein
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2’,3,4,4’-tetrahydroxy Chalcone |
Apoptosis
,
EGFR
,
Others
,
PDE
,
Autophagy
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Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR. |
| T7792 |
Hispidin
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Endogenous Metabolite
,
PKC
|
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Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties |
| T2999 |
Gastrodin
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Gastrodine |
Others
|
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Gastrodin (Gastrodine), an anti-inflammatory polyphenol, is extracted from Chinese natural herbal Gastrodia elata Blume. and benefits neurodegenerative diseases. |
| T19408 |
M-Coumaric acid
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Endogenous Metabolite
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m-Coumaric acid, a polyphenol metabolite derived from caffeic acid, is produced by gut microflora. Its presence in human biofluids varies with diet. |
| T67709 |
Hispolon
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Others
|
|
Hispolon is a polyphenol. Hispolon can be isolated from Phellinus linteus. Hispolon exhibits anticancer, antidiabetic, antiviral, hepatoprotective, antioxidant, and anti-inflammatory activities. |
| T0122 |
Bergenin
|
Cuscutin,Bengenin |
Apoptosis
,
IL Receptor
,
Virus Protease
,
TNF
,
NF-κB
,
Antibacterial
,
NOD
,
Autophagy
,
Antifungal
|
|
Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action. |
| T3807 |
(-)-Gallocatechin gallate
|
(-)-gallocatechin-3-O-gallate,(-)-Gallocatechol gallate,Gallocatechin gallate |
Others
|
|
(-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM. |
| T6917 |
Oleuropein
|
|
Apoptosis
,
Aromatase
,
ROS
,
PPAR
|
|
Oleuropein is an antioxidant polyphenol isolated from olive leaf. |
| T3018 |
Protocatechualdehyde
|
Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde |
Reactive Oxygen Species
,
Antibacterial
|
|
Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an anti... |
| T4S0999 |
(2S)-Isoxanthohumol
|
Isoxanthohumol |
Virus Protease
,
HSV
|
|
1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic ... |
| T13808 |
P-Coumaric Acid Ethyl Ester
|
Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate |
Others
,
Drug Metabolite
|
|
p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato... |
| T5429 |
Theaflavin 3,3'-digallate
|
8-Gingerol,TFDG |
Virus Protease
,
Antioxidant
,
HIV Protease
,
HSV
|
|
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... |
| T2988 |
(-)-Epigallocatechin Gallate
|
Epigallocatechol Gallate,EGCG |
Ferroptosis
,
Reactive Oxygen Species
,
HIV Protease
,
Mitochondrial Metabolism
,
Endogenous Metabolite
,
Autophagy
|
|
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor... |
| TN1722 |
Hamamelitannin
|
|
Antifection
|
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Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig... |
| TN1969 |
N-(p-Coumaroyl) serotonin
|
|
PDGFR
|
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N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving... |
| T35972 |
4-Hydroxy-hippuric acid
|
4-Hydroxy-hippuric acid,p-Hydroxyhippuric Acid,para-Hydroxyhippuric Acid |
|
|
Polyphenol metabolite. |
| T12543 |
Proanthocyanidin A4
|
|
Others
|
|
Proanthocyanidin A4 is a polyphenol isolated from the root of E. sinica, with anti-inflammatory effects. |
| T83417 |
2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
|
|
|
|
Compound 29, 2-(3-Hydroxy-2-oxoindolin-3-yl)acetic acid, is a natural polyphenol found in hop bract [1]. |
| TN1909 |
Malvidin-3-glucoside chloride
|
Malvidin-3-O-glucoside chloride,Oenin chloride |
Others
|
|
Malvidin-3-glucoside chloride (Oenin chloride) has antioxidant activity, alone is not oxidized in the presence of grape polyphenol oxidase. Malvidin-3-O-glucoside chloride's color stabilization at a higher pH can be expl... |
