| T5S1895 |
Norisoboldine
|
Laurelliptine,(+)-Laurelliptine |
MAPK
,
Adenosine Receptor
|
|
1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo... |
| T4587 |
Mirificin
|
BCP10902,Puerarin Apioside |
Tyrosinase
|
|
Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant. |
| T3848 |
7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside
|
Isomucronulatol 7-O-glucoside,7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside |
Others
|
|
7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside (Isomucronulatol 7-O-glucoside) is a natural product from Astragalus membranaceus |
| TCS2170 |
2,5-Dihydroxyacetophenone
|
Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP |
ERK
,
NF-κB
,
Tyrosinase
|
|
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... |
| TN3273 |
8-Deacetylyunaconitine
|
|
Others
|
|
8-Deacetylyunaconitine is a a diterpenoid alkaloid derived from Aconitum Vilmorinian Radix. |
| TN7027 |
Benzoylalbiflorin
|
Paeonivayin |
Others
|
|
Benzoylalbiflorin (Paeonivayin) is a monoterpenoid isolated from Radix Paeoniae Alba. |
| T2986 |
Jatrorrhizine hydrochloride
|
|
Others
|
|
Jatrorrhizine hydrochloride is extracted from berberidis, radix. |
| TN1927 |
Methyl Kakuol
|
1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one |
TRP/TRPV Channel
|
|
Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 µM and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix. |
| T3773 |
Oxypaeoniflorin
|
Oxypaeoniflora |
Others
|
|
Oxypaeoniflorin (Oxypaeoniflora) is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba. |
| T4961 |
9''-Methyl salvianolate B
|
9'-Methyl lithospermate B |
Others
|
|
9'-Methyl lithospermate B is a phenolic compound extracted from Radix Salvia miltiorrhizae. |
| T3S1896 |
Lindenenol
|
Linderene,Lindeneol |
Others
,
Antibacterial
|
|
Lindenenol (Linderene) is isolated from Radix linderae and has antioxidant and antibacterial effects. |
| TN7243 |
Fallaxsaponin A
|
|
|
|
Fallaxsaponin A is isolated from the alkaline hydrolysis products of total saponins in Radix Palygalae. |
| TN7111 |
Hydroxyisogermafurenolide
|
|
Others
|
|
Hydroxyisogermafurenolide is a natural prodrct from Curcumae Radix. |
| T2S0473 |
Rehmannioside C
|
|
Others
|
|
Rehmannioside C is an iridoid glucoside. Rehmannioside C has been isolated from Radix Rehmanniae Praeparata[1]. |
| TN1782 |
(+)-Isolariciresinol
|
(+)-Cyclolariciresinol,Isolariciresinol |
Immunology/Inflammation related
|
|
(+)-Isolariciresinol ((+)-Cyclolariciresinol) is extracted from Radix Isatidis and shows antioxidant and anti-inflammatory activities and can be used in studies about rheumatism. |
| T3387 |
Phytolaccagenin
|
|
Others
,
Antibacterial
|
|
Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae which are widely used in East Asian countries for the treatment of inflammation-related diseases. |
| T6S1880 |
Benzoylaconine
|
Pikraconitin,Isaconitine,Benzoylaconitine |
Others
|
|
Benzoylaconine (Isaconitine) is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi). Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabol... |
| T0036 |
18β-Glycyrrhetinic acid
|
Enoxolone,Glycyrrhetin |
Dehydrogenase
,
Endogenous Metabolite
|
|
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. |
| T2983 |
3,4,5-Trimethoxycinnamic acid
|
3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid |
GABA Receptor
,
Endogenous Metabolite
|
|
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex. |
| T3S0012 |
Coniferyl ferulate
|
|
P-gp
,
GST
|
|
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental GST (IC50: 0.3 μM). It also reverses multidrug resistance ... |
| T3860 |
Isoliquiritin apioside
|
|
MMP
,
p38 MAPK
,
NF-κB
|
|
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse... |
| T10383 |
Asatone
|
|
NF-κB
|
|
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways. |
| T3018 |
Protocatechualdehyde
|
Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde |
Reactive Oxygen Species
,
Antibacterial
|
|
Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an anti... |
| T5S2204 |
Sibiricose A6
|
|
Antioxidant
|
|
1. Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression. 2. Sibiricose A6 shows potent antioxidant activity. |
| T5S2195 |
Sibiricose A5
|
|
Dehydrogenase
|
|
Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia. |
| TN1683 |
Gentisin
|
|
DNA/RNA Synthesis
|
|
Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity. |
| T6S1653 |
Albiflorin
|
Alibiflorin |
Reactive Oxygen Species
|
|
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ... |
| T3019 |
Physcion
|
Physcione,Parietin,Rheochrysidin |
Dehydrogenase
,
Antibacterial
|
|
Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM... |
| T3891 |
Oroxylin A-7-O-glucuronide
|
Oroxylin A Glucoronide,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide |
Others
|
|
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM)... |
| T7090 |
Jionoside A1
|
|
Others
|
|
Jionoside A1 is isolated and purified from the roots of Rehmannia glutinosa. It displays dose-dependent immune-enhancement activity and possesses moderate neuroprotective activities on H2O2-treated SH-SY5Y cells. |
| T3903 |
Angoroside C
|
|
Prostaglandin Receptor
|
|
Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidative activity in reducing the oxidized OH adducts of dAMP and ... |
| TN1440 |
Beta-Hydroxyisovalerylshikonin
|
|
EGFR
,
Tyrosine Kinases
,
Prostaglandin Receptor
,
Src
,
AMPK
,
Fatty Acid Synthase
|
|
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de... |
| T5702 |
Tenuifoliside B
|
|
Dehydrogenase
|
|
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi... |
| T38524 |
Paeoniflorin sulfite
|
|
|
|
During the sulfur-fumigation process of Paeoniae Radix Alba, Paeoniflorin, which serves as a principal constituent, can be converted into Paeoniflorin sulfite. |
| T83593 |
(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone
|
|
|
|
(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone, an angular-type pyranocoumarin, is a natural product isolated from Peucedani Radix. [1] [2]. |
| T83365 |
3′-O-Angeloylhamaudol
|
|
|
|
3′-O-Angeloylhamaudol, a coumarin derivative, is isolated from Radix Saposhnikoviae [1]. |
| TN1447 |
L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
|
FT-0775891,Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside |
Others
|
|
Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis. |
| T81020 |
Tenaxin I
|
|
|
|
Tenaxin I, an extract from Radix Scutellariae, exhibits neuraminidase inhibitory activity [1]. |
| TN5094 |
Tangshenoside I
|
|
Glucokinase
|
|
Tangshenoside I might be a potential bioactive marker related to the hematopoietic and immunologic functions of Codonopsis Radix, which could be recommended as the index compound. It has α-glucosidase inhibition activity... |
| T75433 |
Norisoboldine hydrochloride
|
|
|
|
Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ... |
