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カタログ番号 | 製品名 | 別名 | ターゲット |
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T2567 | Etonogestrel | 3-Oxodesogestrel,3-keto-Desogestrel,Nexplanon,Implanon | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives. | |||
T10803 | CHMFL-KIT-033 | c-Kit | |
CHMFL-KIT-033 is an effective and selective c-KIT inhibitor with an IC50 value of 45 nM for c-KIT T670I mutant in gastrointestinal stromal tumors. | |||
T5409 | AZD3229 | c-Kit | |
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel. | |||
T4605 | NT157 | IGF-1R , STAT | |
NT157 is a small molecule tyrphostin targeting IRS protein and has the potential to inhibit IGF-1R and STAT3 signaling pathways in TME cancer cells and stromal cells, resulting in decreased cancer cell survival. | |||
T1776 | Plerixafor | JM3100,AMD 3100,AMD-3329 | Virus Protease , HIV Protease , CXCR |
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | |||
T8402 | Regorafenib Hydrochloride | BAY73-4506 hydrochloride | Raf , VEGFR , c-RET , PDGFR , Autophagy |
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity | |||
T17208 | USL311 | CXCR | |
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing... | |||
T1776L | Plerixafor octahydrochloride | JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl | Virus Protease , HIV Protease , CXCR |
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow a... | |||
T16686 | Pyr10 | TRP/TRPV Channel | |
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits... | |||
T16104 | ML-9 | Myosin , Akt | |
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction ... | |||
T77697 | BML-278 | BML278,BML 278 | Sirtuin , Histone Methyltransferase |
BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 ind... | |||
T70062 | Osteoprotegerin | ||
Osteoprotegerin is a soluble secreted member of the tumor necrosis factor receptor superfamily, inhibiting osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, leading... | |||
T71894 | AZD3229 Tosylate | ||
AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal stromal tumors (GISTs). | |||
T22859 | Imatinib hydrochloride | Others | |
Imatinib is a multi-target inhibitor of v-Abl, c-Kit, and PDGFR (IC50: 0.6 μM, 0.1 μM, and 0.1 μM, respectively). Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs), and... | |||
T40908 | KLD-12 | ||
KLD-12, a 12-residue self-assembling peptide, displays properties that promote chondrogenic differentiation of bone marrow stromal cells (BMSCs). Moreover, KLD-12 hydrogel can effectively fill full-thickness osteochondra... | |||
T16103 | ML-9 Free Base | Others | |
ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal ... | |||
T82851 | BMP2-derived peptide | ||
BMP2-derived peptide, encompassing amino acids 73 to 92 of BMP-2, induces osteogenic differentiation in bone marrow stromal cells (BMSCs) and augments bone regeneration [1]. | |||
T82507 | Ecleralimab | CSJ-117,NVP-CSJ117 | |
Ecleralimab (CSJ-117; NVP-CSJ117), a Fab-IgG1-λ2 monoclonal antibody, selectively targets thymic stromal lymphopoietin (TSLP). It is typically produced using a Chinese Hamster Ovary (CHO) cell expression system [1]. | |||
T76327 | CTCE-0214 | ||
CTCE-0214, a chemokine CXC receptor 4 (CXCR4) agonist and SDF-1α (stromal cell-derived factor-1α) peptide analog, exhibits anti-inflammatory properties. It is applicable in the research of inflammation, sepsis, and syste... | |||
T68861 | MS-0022 | ||
MS-0022 is a SMO antagonist. MS-0022 showed effective Hh signaling pathway inhibition at the level of SMO in the low nM range, and Hh pathway inhibition downstream of Suppressor of fused (SUFU) in the low µM range. MS-00... | |||
T69081 | KRH-1636 | ||
KRH-1636 is an orally active, selective and extremely potent CXC chemokine receptor 4 antagonist. KRH-1636 exhibits a potent and selective anti-HIV-1 activity. KRH-1636 efficiently blocked replication of various T cell ... | |||
T69288 | CEP-7055 | ||
CEP-18770 is an orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome, with potential antineoplastic activity. Proteasome inhibitor CEP 18770 represses the ... | |||
T37265 | 15(R)-Lipoxin A4 | 15(R)-Lipoxin A4,AT-Lipoxin A4 | |
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspiri... | |||
T68306 | INCB16562 | ||
INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 markedly selective over JAK3. Treatment of myeloma cells with INCB16562 potently inhibited interleukin-6 (IL-6)-induced p... | |||
T83880 | C18 Ceramide-1-phosphate (d18:1/18:0) ammonium | Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate | |
C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (H... | |||
T68321 | AS1940477 | ||
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blo... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T5751 | Tigogenin | Others | |
Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis. | |||
T2820 | Glycitin | Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside | Others , Influenza Virus , Antibacterial |
Glycitin (Glycitein 7-O-β-glucoside), a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. | |||
T3674 | Hydroxysafflor yellow A | HSYA,Safflomin A | TGF-beta/Smad |
Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit... | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-05453 | TSLP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
TSLP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.5 kDa and the accession number is A0A7N9CAT7. | |||
TMPY-05220 | TSLP Protein, Human, Recombinant (R127A & R130S, His) | Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-02428 | TSLP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TSLP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9JIE6. | |||
TMPY-03235 | BST2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
BST2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q10589. | |||
TMPY-05756 | TSLP Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPY-06505 | TSLP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.50 kDa and the accession number is NP_149024.1. | |||
TMPK-00482 | TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated | Cynomolgus | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ... | |||
TMPK-00038 | TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) | Human | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ... | |||
TMPK-00037 | TSLP Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ... | |||
TMPK-00040 | TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated | Human | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ... | |||
TMPK-00039 | TSLP Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ... | |||
TMPY-01001 | SDF-2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SDF-2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is Q6IBU4. | |||
TMPY-03037 | CD157 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
CD157 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q63072. | |||
TMPY-03038 | CD157 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CD157 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is Q63072. | |||
TMPY-02274 | SDF-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
SDF-2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is Q9DCT5. | |||
TMPY-00968 | CD157 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD157 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is Q10588-1. | |||
TMPJ-01338 | TSLP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen pre... | |||
TMPY-03193 | BST2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
BST2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q10589. | |||
TMPY-01605 | STIM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human ... | |||
TMPJ-00530 | TSLPR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1. | |||
TMPJ-00265 | Serpin F1 Protein, Mouse, Recombinant | Mouse | E. coli |
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and ... | |||
TMPY-01178 | CD157 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD157 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is A0A0R4J190. | |||
TMPY-04742 | BST2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
BST2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is Q8R2Q8. | |||
TMPY-02674 | BST2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
BST2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is Q8R2Q8. | |||
TMPJ-00531 | TSLPR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1. | |||
TMPJ-00202 | CD157 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow str... | |||
TMPJ-00952 | CXCL12 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, an... | |||
TMPJ-01466 | Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) | Human | HEK293 Cells |
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ... | |||
TMPJ-00038 | IL-7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a... | |||
TMPJ-00832 | Granzyme D/GZMD Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b... | |||
TMPK-01331 | TSLPR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of t... | |||
TMPK-00280 | B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expr... | |||
TMPK-01298 | BST2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res... | |||
TMPK-00446 | VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ... | |||
TMPK-00445 | VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ... | |||
TMPY-01890 | CLIC4 Protein, Human, Recombinant (His) | Human | E. coli |
Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem... | |||
TMPJ-01037 | CXCR4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor ... | |||
TMPJ-00509 | DLK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Protein Delta Homolog 1 (DLK-1) is a transmembrane protein which contains a signal peptide, an extracellular domain with six tandem epidermai growth factor (EGF)-like domains, a single pass transmembrane domain, and a sh... | |||
TMPJ-00006 | CXCL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal ... | |||
TMPJ-00852 | CCL2 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the... | |||
TMPJ-00993 | CCL5 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory s... | |||
TMPJ-00055 | Podoplanin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmem... | |||
TMPY-00886 | MMP-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the ma... | |||
TMPY-04391 | Lyn Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L8000 | Stem Cell Differentiation Compound Library | 1197 compounds | |
A unique collection of 1197 stem cell differentiation signaling targeted compounds for high throughput and high content screening; |